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VP4

Euk-Vir

Orbivirus_SX-2017a

VP4__YP_009345882__Orbivirus_SX-2017a__1955493

Identity

Accession:
YP_009345882 ↗
Protein ID:
VP4
Kingdom:
euk

Quality

94.5 mean pLDDT

Cluster

View cluster (18 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 7-117
PDB
Domain cluster: rep: VP4__YP_008719907__Mobuck_virus__1408137__D7-110
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05059.21 best Orbi_VP4 149.7 1.30e-43 100.0% 17.4%
D2 high residues 172-390
PDB
Domain cluster: rep: polyA_polymerase_reg_subunit__YP_009001345__Pithovirus_sibericum__1450746__D33-211
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05059.21 best Orbi_VP4 324.2 1.80e-96 100.0% 34.4%
CATH (71)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2jhpA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.99 95.0 8.42e-01 100.0% 73.7%
1ej0A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.77 60.0 6.55e-01 82.2% 96.7%
1eamA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.76 71.0 6.43e-01 98.6% 88.4%
6jp6D01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.72 61.0 6.08e-01 88.1% 93.3%
3ftdA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.71 53.0 5.92e-01 82.6% 95.5%
4m37A01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.70 41.0 4.94e-01 74.4% 85.5%
2bm8B02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 52.0 5.86e-01 82.6% 99.4%
3futA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 53.0 5.55e-01 82.6% 86.4%
4xrpC01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.68 50.0 5.62e-01 75.8% 100.0%
4obxA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.68 51.0 5.01e-01 77.2% 93.2%
4pioA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.68 50.0 5.49e-01 75.8% 93.9%
1jqdA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.67 50.0 4.59e-01 76.7% 92.0%
8k1fC01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.67 51.0 5.37e-01 77.6% 99.5%
3lkdA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.66 61.0 5.61e-01 98.6% 86.9%
1h2bA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.66 42.0 5.17e-01 90.4% 99.3%
1u2zA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.66 48.0 5.25e-01 84.0% 90.6%
4g1vA03 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.64 40.0 5.02e-01 80.4% 100.0%
1g38A01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.64 57.0 5.73e-01 95.9% 93.3%
3re1A02 3.40.50.10090 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.63 36.0 4.58e-01 71.7% 94.5%
3jy6D02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.63 39.0 4.85e-01 74.4% 100.0%
5eccA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.63 39.0 4.54e-01 97.7% 85.4%
5kc8A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.62 45.0 5.06e-01 95.9% 98.1%
4j8lA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.62 42.0 4.11e-01 100.0% 60.8%
3qnmA01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.62 40.0 4.88e-01 92.7% 100.0%
3ed5A01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.62 38.0 4.47e-01 98.2% 88.4%
2hqbA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.62 40.0 4.71e-01 95.0% 93.4%
3vywA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 52.0 5.06e-01 87.7% 86.0%
2wjwA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 44.0 5.01e-01 95.9% 99.4%
6g80B01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 49.0 4.95e-01 84.0% 91.0%
2yy7A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.60 52.0 4.60e-01 91.3% 94.2%
1qfjA02 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.60 37.0 4.68e-01 79.5% 100.0%
7rbpA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.59 48.0 4.99e-01 98.6% 92.0%
2g8lA03 3.40.50.10880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Uncharacterised protein PF01937, DUF89, domain 3 0.59 40.0 4.72e-01 81.3% 98.7%
5yb0J01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.58 41.0 3.98e-01 99.5% 63.8%
3ay3A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 50.0 4.96e-01 91.3% 98.2%
6uh2A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 51.0 4.99e-01 94.5% 96.6%
1b93B00 3.40.50.1380 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Methylglyoxal synthase-like domain 0.57 35.0 4.16e-01 76.7% 88.1%
3un1C00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 49.0 4.86e-01 92.2% 93.6%
3qp9D00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 53.0 4.11e-01 100.0% 93.4%
7yiyA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.56 46.0 4.46e-01 100.0% 76.6%
6p66D01 3.40.91.30 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.56 29.0 3.93e-01 87.7% 97.2%
6dvsA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.56 41.0 4.25e-01 100.0% 78.1%
3dmyA02 3.40.50.261 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains 0.55 34.0 4.10e-01 73.5% 93.6%
3uw2A01 3.40.120.10 Alpha Beta › 3-Layer(aba) Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 › Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 0.55 32.0 3.69e-01 95.0% 77.4%
4bj1A02 3.40.50.12060 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 36.0 4.29e-01 93.2% 98.0%
1jbwA02 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.55 30.0 3.95e-01 80.8% 100.0%
4r5zA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.54 44.0 4.38e-01 100.0% 81.1%
1cs1A01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.54 44.0 4.25e-01 96.3% 76.7%
6i3mE02 3.40.50.10470 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Translation initiation factor eif-2b; domain 2 0.53 45.0 4.75e-01 89.5% 100.0%
2ihtA02 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.53 37.0 4.12e-01 96.8% 91.5%
1jztA00 3.40.50.10260 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › YjeF N-terminal domain 0.53 48.0 4.65e-01 97.7% 99.6%
2vbfA02 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.53 34.0 3.89e-01 96.3% 85.9%
2panA02 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.52 36.0 4.00e-01 96.8% 89.8%
5tshA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 45.0 4.22e-01 93.6% 89.9%
2hxvA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.52 40.0 4.21e-01 82.6% 88.9%
3b1dA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.52 45.0 4.47e-01 100.0% 88.9%
2zjgA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.52 45.0 4.25e-01 100.0% 78.1%
1uxtA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.52 37.0 3.49e-01 98.2% 59.0%
5vogA00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 38.0 4.17e-01 92.7% 93.2%
5mypA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.51 39.0 3.63e-01 98.2% 61.7%
1cl1A01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.51 44.0 4.21e-01 92.2% 78.3%
5ucdA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.51 38.0 3.72e-01 98.2% 70.7%
2oap202 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 44.0 4.13e-01 99.1% 74.0%
4qgsA01 3.40.50.1970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 36.0 4.08e-01 72.6% 95.3%
4emyA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.51 45.0 4.45e-01 96.3% 95.4%
2iw1A01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.51 41.0 4.38e-01 91.3% 100.0%
4piwA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.51 43.0 4.25e-01 95.9% 83.8%
1zpdA02 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.51 34.0 3.83e-01 97.7% 88.3%
2jisB02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.50 46.0 4.40e-01 97.3% 96.8%
4k2bA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.50 42.0 3.78e-01 96.3% 64.1%
4ritA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.50 45.0 4.47e-01 100.0% 90.7%
ECOD (77)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
185903 2003.1.5.43 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Orbi_VP4 0.99 87.0 9.29e-01 92.2% 100.0%
9332 2003.1.5.11 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PARP_regulatory 0.76 71.0 6.38e-01 98.2% 88.0%
3785963 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.75 62.0 5.97e-01 85.4% 94.2%
3600323 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.74 64.0 5.97e-01 90.0% 94.3%
3940625 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.73 58.0 5.99e-01 82.2% 86.7%
4100871 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.73 58.0 6.20e-01 82.6% 95.4%
4235408 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.73 59.0 5.63e-01 83.6% 92.7%
4037133 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.73 58.0 6.07e-01 83.1% 92.2%
3287448 2003.1.5.46 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS 0.72 54.0 5.09e-01 76.7% 79.2%
4941471 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.71 54.0 5.06e-01 78.5% 86.3%
4494949 2003.1.5.25 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GidB 0.71 50.0 5.35e-01 75.8% 81.6%
5080701 2003.1.5.445 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GvpD_bR2 0.71 54.0 5.62e-01 78.5% 100.0%
4635658 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.71 55.0 5.61e-01 80.4% 97.2%
3738575 2003.1.5.71 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_33 0.70 52.0 4.53e-01 75.3% 83.7%
None — 0.70 50.0 5.76e-01 72.6% 97.6%
3727588 2003.1.5.71 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_33 0.70 52.0 4.49e-01 77.2% 77.6%
3607825 2003.1.5.79 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.70 52.0 4.80e-01 77.2% 84.6%
3838658 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.69 47.0 5.58e-01 89.0% 99.3%
4518850 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.68 52.0 3.99e-01 77.6% 79.1%
None — 0.68 62.0 5.71e-01 95.9% 87.3%
4267972 2003.1.5.49 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_30 0.67 51.0 4.89e-01 78.1% 82.8%
3928319 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.67 50.0 4.99e-01 77.2% 81.3%
3632527 2003.1.5.79 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.67 50.0 4.57e-01 76.3% 90.4%
4288608 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.67 53.0 4.37e-01 82.6% 93.9%
4587300 2003.1.5.25 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GidB 0.66 50.0 5.13e-01 77.2% 96.7%
4016342 2003.1.5.67 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12 0.66 52.0 4.83e-01 81.7% 75.3%
4967515 2003.1.5.82 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.66 53.0 5.02e-01 82.6% 93.3%
3815647 2003.1.5.220 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF26055 0.66 55.0 5.15e-01 97.7% 72.1%
4998506 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.65 52.0 5.45e-01 82.2% 91.5%
4072936 2003.1.5.53 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr 0.64 52.0 5.33e-01 83.1% 90.9%
2329746 2003.1.5.67 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12 0.64 51.0 4.79e-01 82.6% 80.4%
3692137 2003.1.5.79 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.64 52.0 4.53e-01 83.6% 85.1%
4967531 2003.1.5.41 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › RMNT_CmcI 0.64 52.0 5.03e-01 84.5% 87.3%
4036368 2003.1.5.71 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_33 0.64 51.0 4.38e-01 83.6% 82.6%
4315670 2006.1.4.17 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › DUF188 0.63 36.0 4.66e-01 91.8% 97.6%
None — 0.63 53.0 5.26e-01 96.3% 84.8%
None — 0.62 54.0 4.34e-01 91.3% 94.3%
153143 2003.1.5.49 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_30 0.61 52.0 4.61e-01 87.7% 67.0%
3838965 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.61 38.0 4.56e-01 77.2% 90.0%
4345229 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.61 52.0 5.12e-01 90.0% 100.0%
4951140 2007.9.1.3 ↗ a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › CAP12-PCTIR_TIR 0.61 35.0 4.35e-01 92.2% 92.3%
None — 0.61 53.0 4.31e-01 91.8% 93.8%
2541848 2003.1.1.69 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2 0.60 51.0 4.86e-01 88.6% 96.9%
4202238 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.60 49.0 4.58e-01 84.0% 85.3%
3944223 2003.1.1.69 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2 0.60 49.0 4.89e-01 85.8% 98.7%
4299161 7512.1.1.23 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_52 0.59 34.0 4.18e-01 89.5% 90.2%
4444241 2003.1.5.364 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › NAD_binding_4, Methyltransf_12 0.59 51.0 3.50e-01 90.9% 50.5%
4955563 7512.1.1.3 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 0.59 39.0 4.28e-01 77.2% 81.1%
4254862 7524.1.1.1 ↗ a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › Aldedh 0.58 35.0 3.29e-01 79.5% 48.5%
4094546 2006.1.1.55 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › DUF188 0.58 39.0 4.55e-01 91.8% 96.0%
5030368 7512.1.1.12 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_tran_28_C 0.58 38.0 4.16e-01 76.7% 78.3%
4142829 7512.1.1.82 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › DUF188 0.58 39.0 4.50e-01 91.8% 94.8%
4078373 7512.1.1.16 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Capsule_synth 0.58 39.0 4.35e-01 77.2% 87.1%
3176314 2003.1.1.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.57 51.0 4.53e-01 93.2% 73.4%
3586704 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.57 52.0 4.38e-01 97.7% 90.4%
3404752 7585.1.1.1 ↗ a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Sec1 0.57 35.0 4.25e-01 92.7% 92.4%
3811055 3698.1.1.2 ↗ beta sandwiches › Arginine methyltransferase oligomerization subdomain › Arginine methyltransferase oligomerization subdomain › Arginine methyltransferase oligomerization subdomain › PRMT_C 0.56 49.0 3.42e-01 92.7% 38.2%
4201344 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.56 44.0 4.52e-01 82.2% 88.8%
4990771 2004.1.1.42 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE 0.56 40.0 3.52e-01 99.1% 49.8%
3404159 7512.1.1.1 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT 0.55 43.0 3.25e-01 79.0% 91.4%
3400780 7512.1.1.83 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT, EryCIII-like_C 0.55 43.0 3.32e-01 79.5% 95.6%
4854828 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.54 44.0 4.48e-01 86.3% 98.2%
3213946 2003.1.7.2 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › IF-2B 0.54 45.0 4.74e-01 89.5% 98.5%
4130118 2003.2.1.1 ↗ a/b three-layered sandwiches › Rossmann-like › Formate dehydrogenase/DMSO reductase, domains 2 and 3 › Formate dehydrogenase/DMSO reductase, domains 2 and 3 › Molybdopterin 0.53 41.0 4.26e-01 80.4% 90.0%
5036272 2003.1.1.48 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › YjeF_N 0.53 47.0 4.71e-01 94.1% 97.3%
3933604 2003.1.7.2 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › IF-2B 0.53 44.0 4.61e-01 90.4% 97.9%
5025765 2003.1.4.1 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › TPP_enzyme_M 0.53 34.0 3.90e-01 96.3% 87.5%
3685521 2003.1.4.1 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › TPP_enzyme_M 0.52 35.0 3.87e-01 96.8% 82.3%
4932458 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 40.0 3.70e-01 91.8% 59.3%
3198343 7598.1.1.1 ↗ a/b three-layered sandwiches › Resistance protein Tm-1 first domain › Resistance protein Tm-1 first domain › Resistance protein Tm-1 first domain › UPF0261 0.52 38.0 4.07e-01 98.2% 85.8%
3975723 7512.1.1.30 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.52 38.0 4.34e-01 87.2% 100.0%
4046241 7510.1.1.3 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › FA_synthesis 0.52 32.0 3.68e-01 75.8% 83.9%
3284365 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.51 38.0 4.09e-01 98.2% 87.0%
3496182 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.51 44.0 3.82e-01 91.3% 87.8%
4034308 2488.1.1.1 ↗ a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › SpoU_methylase 0.51 34.0 3.85e-01 92.2% 87.1%
3404623 7512.1.1.83 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT, EryCIII-like_C 0.50 44.0 3.41e-01 92.7% 93.1%
3972669 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.50 40.0 4.34e-01 91.8% 100.0%
D3 medium residues 391-442
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05059.21 best Orbi_VP4 54.4 8.80e-15 100.0% 8.0%
CATH (50)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4hwgA02 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.67 48.0 3.45e-01 76.9% 57.3%
2nx2A00 3.40.50.450 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.64 55.0 3.86e-01 100.0% 61.8%
2afbB00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.64 53.0 3.32e-01 100.0% 57.7%
2vsqA03 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.64 52.0 3.64e-01 98.1% 55.8%
4m37A01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.63 49.0 3.64e-01 88.5% 39.3%
3tviA01 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.62 42.0 2.68e-01 71.2% 61.1%
1v8oH00 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.62 43.0 3.32e-01 76.9% 45.6%
1xdwA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.61 52.0 3.57e-01 100.0% 64.5%
1gzuA00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.61 48.0 3.27e-01 92.3% 64.3%
3oh8A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.61 49.0 3.28e-01 100.0% 45.4%
7va8A01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.61 46.0 3.00e-01 86.5% 66.8%
5u95B01 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.60 48.0 3.54e-01 100.0% 51.2%
1brmA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.60 48.0 3.66e-01 100.0% 58.3%
3dnfA03 3.40.1010.20 Alpha Beta › 3-Layer(aba) Sandwich › Cobalt-precorrin-4 Transmethylase; domain 1 › 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain 0.60 46.0 3.87e-01 90.4% 56.6%
5jgjA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.60 48.0 3.25e-01 100.0% 72.8%
3ru6B00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.58 45.0 3.14e-01 94.2% 47.7%
4zv9A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 47.0 3.22e-01 100.0% 73.9%
2w4lB00 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.58 42.0 3.20e-01 86.5% 64.3%
1nijA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 46.0 3.27e-01 100.0% 76.1%
4kp1A02 3.30.499.10 Alpha Beta › 2-Layer Sandwich › Aconitase; domain 3 › Aconitase, domain 3 0.57 47.0 3.53e-01 100.0% 60.1%
2fwrA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 46.0 3.23e-01 98.1% 42.2%
1jw9B00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 45.0 3.08e-01 100.0% 36.3%
1zynA00 3.40.30.80 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › 0.56 41.0 2.87e-01 82.7% 30.1%
4cjxA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 47.0 3.55e-01 100.0% 62.1%
2fp4A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 43.0 3.46e-01 92.3% 60.2%
2e7jA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.56 46.0 3.10e-01 100.0% 50.4%
3dnfB01 3.40.1010.20 Alpha Beta › 3-Layer(aba) Sandwich › Cobalt-precorrin-4 Transmethylase; domain 1 › 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain 0.56 43.0 3.61e-01 90.4% 56.0%
3r2uA02 3.40.250.10 Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain 0.55 42.0 3.68e-01 84.6% 59.5%
3lteD00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 47.0 3.64e-01 100.0% 61.8%
1ba3A02 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 40.0 2.85e-01 88.5% 23.8%
4joqA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.54 41.0 3.21e-01 98.1% 60.0%
1zu0A03 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.54 36.0 2.41e-01 71.2% 56.9%
1kamA00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.53 41.0 2.99e-01 92.3% 35.0%
3lkbA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 41.0 3.13e-01 100.0% 62.9%
4evsA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 43.0 3.14e-01 100.0% 66.1%
1utbB01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.53 38.0 2.90e-01 76.9% 80.5%
5uh0A02 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.53 38.0 3.22e-01 88.5% 44.1%
4ab5B01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.53 41.0 3.26e-01 88.5% 87.8%
1p99A01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.53 41.0 3.15e-01 94.2% 94.4%
4b4uB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 41.0 3.29e-01 100.0% 45.9%
2jfzA02 3.40.50.1860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 40.0 3.27e-01 90.4% 71.2%
7vevA01 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.52 41.0 2.82e-01 100.0% 50.8%
1sy7A02 1.20.1370.20 Mainly Alpha › Up-down Bundle › Hemocyanin, N-terminal domain › Catalase, four-helical domain 0.52 39.0 3.68e-01 82.7% 71.9%
3netB02 3.40.50.800 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain 0.52 36.0 3.15e-01 80.8% 68.4%
3kosA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.52 34.0 2.86e-01 71.2% 44.7%
2ohwA00 3.30.1330.30 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Ribosomal protein L30/S12 0.51 41.0 3.29e-01 100.0% 50.8%
4n4rB00 3.30.160.150 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain 0.51 34.0 2.60e-01 71.2% 25.2%
1hyuA04 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.51 38.0 3.33e-01 86.5% 58.5%
3lzdA01 3.40.50.11840 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Diphthamide synthesis DPH1/DPH2 domain 1 0.50 37.0 3.27e-01 88.5% 52.6%
2b3yA03 3.30.499.10 Alpha Beta › 2-Layer Sandwich › Aconitase; domain 3 › Aconitase, domain 3 0.50 36.0 2.52e-01 84.6% 27.7%
ECOD (53)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3960434 323.1.1.0 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.68 58.0 3.78e-01 100.0% 54.9%
3395805 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.67 56.0 3.71e-01 100.0% 43.3%
3849205 207.1.1.22 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_6 0.66 55.0 3.58e-01 100.0% 97.8%
3530704 207.1.1.22 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_6 0.63 53.0 3.20e-01 100.0% 27.2%
4945945 2006.1.4.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.61 45.0 3.17e-01 82.7% 33.0%
4012789 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.61 50.0 3.22e-01 100.0% 52.9%
3188708 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.60 49.0 3.45e-01 100.0% 45.9%
5036375 2007.6.1.5 ↗ a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › bact-PGI_C 0.60 51.0 3.68e-01 100.0% 45.6%
4570718 2003.1.11.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Formate/glycerate dehydrogenase catalytic domain-like 0.60 50.0 3.31e-01 100.0% 51.2%
3692250 7579.1.1.18 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_2 0.60 49.0 3.20e-01 100.0% 80.7%
3958604 2003.1.2.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FMO-like 0.59 48.0 3.31e-01 94.2% 28.1%
3686713 2003.1.1.37 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 2-Hacid_dh_C 0.59 46.0 3.31e-01 100.0% 51.7%
3710515 7585.1.1.1 ↗ a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Sec1 0.58 48.0 3.79e-01 100.0% 62.4%
5049503 7523.1.1.3 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_5 0.58 44.0 2.83e-01 84.6% 58.2%
3593379 7585.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins 0.58 47.0 3.65e-01 100.0% 63.7%
4947957 314.1.1.2 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_2b 0.57 45.0 2.82e-01 90.4% 20.6%
4013371 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.57 45.0 3.54e-01 92.3% 60.0%
4191563 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.57 44.0 3.06e-01 100.0% 43.3%
5060291 7574.1.1.4 ↗ a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › POR_N 0.56 45.0 3.14e-01 100.0% 59.1%
3962488 2003.1.8.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › MurCD/PglD N-terminal domain-like › Epimerase 0.56 39.0 3.74e-01 76.9% 78.5%
4547659 2007.1.16.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 0.56 43.0 3.40e-01 96.2% 36.9%
1655466 7587.1.1.1 ↗ a/b three-layered sandwiches › Rossmann-like domain in carbohydrate phosphatases › Rossmann-like domain in carbohydrate phosphatases › Rossmann-like domain in carbohydrate phosphatases › Inositol_P 0.55 45.0 3.53e-01 100.0% 63.9%
None — 0.55 43.0 2.78e-01 100.0% 39.4%
4524622 7523.1.1.15 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › LysR_substrate 0.55 38.0 3.12e-01 73.1% 43.0%
5060193 2005.1.1.13 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CTP_transf_like 0.55 43.0 3.23e-01 90.4% 35.2%
3300169 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.55 44.0 2.73e-01 100.0% 28.1%
3930621 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.55 43.0 3.16e-01 100.0% 49.2%
3791564 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.54 44.0 3.40e-01 100.0% 60.7%
4100593 7585.1.1.1 ↗ a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Sec1 0.54 44.0 3.51e-01 100.0% 68.0%
3605597 2007.1.2.27 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_A-cyclase 0.54 44.0 3.34e-01 94.2% 56.4%
2499611 2007.1.7.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Rossmann-like domain in dehydroquinate synthase-like enzymes › Fe-ADH 0.54 46.0 3.25e-01 100.0% 37.6%
5054594 2007.1.16.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 0.54 39.0 3.30e-01 88.5% 43.0%
3626458 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.54 42.0 2.87e-01 100.0% 40.8%
3940742 2007.1.16.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 0.53 42.0 3.31e-01 90.4% 58.3%
3788305 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.53 42.0 2.74e-01 100.0% 71.3%
3372759 2004.1.1.135 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PIF1 0.53 42.0 2.82e-01 100.0% 21.9%
3997892 2007.1.16.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 0.53 41.0 3.26e-01 90.4% 59.2%
5033383 2007.1.7.3 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Rossmann-like domain in dehydroquinate synthase-like enzymes › Fe-ADH_2 0.53 44.0 3.22e-01 100.0% 48.8%
5042280 2007.1.16.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn 0.53 40.0 3.26e-01 88.5% 58.2%
3486959 2007.1.16.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 0.52 39.0 3.36e-01 88.5% 53.0%
3741050 2007.1.16.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn 0.52 42.0 3.39e-01 100.0% 58.4%
4429742 7523.1.1.15 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › LysR_substrate 0.52 35.0 2.91e-01 71.2% 46.0%
3942640 7523.1.1.15 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › LysR_substrate 0.52 36.0 3.07e-01 76.9% 42.0%
5022606 3110.1.1.21 ↗ a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › PF29526 0.52 40.0 3.18e-01 94.2% 43.1%
4942299 2007.1.16.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn 0.51 39.0 3.26e-01 94.2% 53.9%
5063561 2007.1.16.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 0.51 40.0 3.35e-01 90.4% 48.0%
4890443 2007.1.7.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Rossmann-like domain in dehydroquinate synthase-like enzymes › Fe-ADH 0.51 41.0 2.96e-01 100.0% 36.9%
4124402 7503.1.1.17 ↗ a/b three-layered sandwiches › TolB, N-terminal domain › TolB, N-terminal domain › TolB, N-terminal domain › PF26521 0.51 35.0 2.71e-01 76.9% 31.7%
4203176 7502.1.1.6 ↗ a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › HisZ_C 0.51 33.0 3.25e-01 73.1% 57.1%
1518874 7523.1.1.8 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_1 0.51 37.0 3.06e-01 84.6% 41.4%
3941580 7523.1.1.15 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › LysR_substrate 0.51 34.0 2.39e-01 73.1% 95.6%
4470829 7502.1.1.0 ↗ a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS 0.50 35.0 3.29e-01 76.9% 91.4%
3952847 320.2.1.0 ↗ a+b two layers › R3H domain-like › Ribosomal protein S8, N-terminal domain › Ribosomal protein S8, N-terminal domain 0.50 38.0 3.60e-01 96.2% 78.7%
D4 medium residues 443-506
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05059.21 best Orbi_VP4 83.1 1.80e-23 100.0% 9.9%
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1fgjA01 1.10.780.10 Mainly Alpha › Orthogonal Bundle › Hydroxylamine Oxidoreductase; Chain A, domain 1 › Hydroxylamine Oxidoreductase; Chain A, domain 1 0.57 41.0 2.84e-01 78.1% 24.2%
1pvwA00 3.90.870.10 Alpha Beta › Alpha-Beta Complex › DHBP synthase › DHBP synthase 0.55 45.0 3.19e-01 95.3% 53.4%
2rb9A02 3.90.650.10 Alpha Beta › Alpha-Beta Complex › Phosphoribosyl-aminoimidazole Synthetase; Chain A, domain 2 › PurM-like C-terminal domain 0.54 44.0 3.36e-01 96.9% 55.6%
4hplA00 3.10.260.40 Alpha Beta › Roll › Mlu1-box Binding Protein; DNA-binding Domain › BCL-6 corepressor, PCGF1 binding domain 0.53 36.0 3.06e-01 70.3% 66.4%
6qdjA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 37.0 3.57e-01 76.6% 90.8%
2fg9A01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.51 35.0 2.80e-01 75.0% 49.1%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3706065 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.53 38.0 3.12e-01 79.7% 42.3%
D5 medium residues 507-643
PDB
Domain cluster: rep: VP4__YP_008719907__Mobuck_virus__1408137__D509-646
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05059.21 best Orbi_VP4 222.2 1.40e-65 96.4% 20.8%