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VP5

Euk-Vir

Lebombo_virus

VP5__YP_009507710__Lebombo_virus__40057

Identity

Accession:
YP_009507710 ↗
Protein ID:
VP5
Kingdom:
euk

Quality

71.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 351-501
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00901.25 best Orbi_VP5 216.7 7.50e-64 100.0% 29.8%
D2 medium residues 103-181_236-275_307-348
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00901.25 best Orbi_VP5 44.0 1.60e-11 49.1% 14.8%
PF00901.25 Orbi_VP5 49.3 4.00e-13 27.3% 8.1%
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2v5cA03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.73 37.0 4.17e-01 78.9% 61.5%
3terA00 1.10.287.3550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 37.0 4.29e-01 70.2% 73.1%
7eq1R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.67 43.0 3.56e-01 90.1% 37.5%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.61 40.0 4.33e-01 99.4% 77.4%
4yonA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.59 32.0 2.88e-01 71.4% 38.0%
3ajwA00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 34.0 3.72e-01 73.9% 68.7%
3c1yA02 1.20.1260.110 Mainly Alpha › Up-down Bundle › Ferritin › DNA integrity scanning linker region 0.59 45.0 4.66e-01 87.0% 87.2%
4iu9B02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.58 48.0 4.42e-01 87.6% 86.7%
3ucaA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.57 47.0 3.89e-01 85.7% 63.1%
4gc0A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.56 50.0 4.32e-01 95.7% 87.1%
2fji101 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.56 40.0 3.73e-01 73.9% 69.9%
7utzR02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.55 41.0 3.43e-01 76.4% 89.4%
8ex5A02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.55 48.0 4.33e-01 93.8% 76.6%
3o7pA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.55 48.0 4.36e-01 94.4% 86.2%
7dl9B02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.54 45.0 4.21e-01 88.2% 86.7%
2pfdA03 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.54 39.0 3.61e-01 72.7% 88.2%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.54 40.0 3.28e-01 75.8% 70.1%
4fp4A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.53 47.0 4.04e-01 93.8% 65.4%
4kk2B00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.53 48.0 3.78e-01 98.8% 55.4%
7qoaA01 1.10.4160.10 Mainly Alpha › Orthogonal Bundle › Hydantoin permease › Hydantoin permease 0.53 46.0 3.47e-01 93.2% 88.5%
1he1A00 1.20.120.260 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Virulence factor YopE uncharacterised domain 0.53 37.0 4.03e-01 71.4% 91.9%
8sbeA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.53 47.0 4.39e-01 96.3% 78.6%
1qu7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.52 36.0 3.18e-01 70.2% 85.9%
5ermB00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.52 39.0 3.15e-01 88.2% 40.1%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.52 38.0 3.31e-01 75.8% 72.7%
1k74D00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.52 41.0 3.48e-01 84.5% 84.2%
3vkgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.51 32.0 3.36e-01 96.9% 68.0%
1v4eA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.50 44.0 3.66e-01 94.4% 57.9%
1tj7A02 1.20.200.10 Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) 0.50 46.0 3.84e-01 99.4% 72.8%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.50 36.0 3.22e-01 73.9% 95.8%
6kd7A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.50 44.0 3.51e-01 95.7% 52.6%
5nx5B00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.50 40.0 3.22e-01 88.8% 45.2%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1721532 3733.1.1.1 a+b complex topology › Orbivirus outer capsid protein VP5 › Orbivirus outer capsid protein VP5 › Orbivirus outer capsid protein VP5 › Orbi_VP5 0.90 87.0 5.80e-01 100.0% 48.7%
4015782 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.63 48.0 4.60e-01 83.9% 68.6%
5070376 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.62 54.0 5.00e-01 93.2% 79.0%
4955340 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.61 37.0 4.33e-01 90.7% 84.3%
3263522 5050.1.1.11 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UNC-93 0.60 52.0 4.79e-01 91.9% 82.0%
3921752 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.60 55.0 4.82e-01 98.8% 71.5%
3887929 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.60 30.0 3.50e-01 75.8% 65.0%
5075089 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.59 52.0 4.78e-01 93.2% 85.4%
3458146 5059.1.1.8 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA 0.59 38.0 4.16e-01 77.6% 77.7%
3186833 5059.1.1.8 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA 0.59 38.0 3.89e-01 73.9% 65.2%
3921512 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.59 53.0 4.53e-01 98.1% 74.6%
3336964 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.58 32.0 2.75e-01 74.5% 33.7%
3532393 5050.1.1.6 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › OATP 0.58 51.0 4.18e-01 93.8% 67.0%
4946068 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.58 52.0 4.55e-01 95.0% 76.5%
3672728 5050.1.1.2 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 0.58 53.0 3.54e-01 97.5% 74.8%
4413986 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 50.0 4.22e-01 94.4% 71.5%
3420900 5050.1.1.33 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_5 0.57 50.0 4.48e-01 93.8% 71.1%
3706598 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 49.0 4.47e-01 92.5% 82.3%
5060545 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.56 45.0 3.61e-01 84.5% 50.3%
3421292 5050.1.1.2 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 0.56 50.0 3.96e-01 95.0% 64.4%
3254302 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 49.0 4.28e-01 93.8% 70.8%
5069593 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 49.0 4.59e-01 95.7% 76.4%
3826342 5050.1.1.2 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 0.56 49.0 3.93e-01 95.0% 56.8%
4946929 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 49.0 4.36e-01 94.4% 77.3%
5014011 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 49.0 4.28e-01 93.8% 68.9%
3738413 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 49.0 4.46e-01 96.9% 83.6%
4933555 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.55 45.0 3.68e-01 87.0% 53.2%
5083711 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.55 38.0 3.23e-01 70.2% 61.7%
3936764 5050.1.1.8 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 0.55 47.0 4.25e-01 92.5% 84.5%
4504137 5050.1.1.10 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 0.54 43.0 3.94e-01 83.9% 73.0%
4926931 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.54 42.0 3.52e-01 83.2% 56.1%
4965007 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 47.0 4.31e-01 93.8% 83.8%
3928215 133.1.1.0 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) 0.53 40.0 3.80e-01 77.6% 93.7%
4401422 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 45.0 3.91e-01 93.2% 65.9%
4967591 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.53 42.0 3.50e-01 85.1% 97.9%
3416072 5050.1.1.6 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › OATP 0.53 46.0 4.13e-01 96.3% 78.7%
1700024 5050.1.1.8 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 0.52 42.0 4.03e-01 84.5% 88.8%
3725505 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.52 48.0 4.25e-01 98.1% 76.4%
3698982 5050.1.1.26 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UVB_sens_prot 0.52 45.0 3.82e-01 93.8% 57.4%
4039745 5050.1.1.53 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MarC 0.52 47.0 4.38e-01 98.8% 81.0%
3406963 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.52 39.0 3.09e-01 76.4% 75.0%
3373319 5059.1.1.8 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA 0.52 39.0 3.76e-01 77.0% 86.1%
5058288 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 42.0 4.15e-01 86.3% 88.0%
5010817 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 38.0 3.71e-01 75.8% 81.7%
4034578 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.51 35.0 3.86e-01 99.4% 85.4%
3686996 5059.1.1.8 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA 0.51 38.0 3.84e-01 76.4% 86.9%
3481351 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 44.0 4.07e-01 91.9% 72.7%
5009721 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.51 44.0 4.00e-01 95.0% 73.6%
3491032 174.1.1.76 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Far-17a_AIG1 0.50 45.0 4.30e-01 98.8% 95.3%
D3 medium residues 182-235_276-306
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00901.25 best Orbi_VP5 61.6 7.80e-17 67.1% 10.7%
CATH (47)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3pjaJ01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.74 52.0 4.52e-01 74.1% 91.6%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.73 51.0 4.61e-01 72.9% 66.4%
3zgzA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.70 51.0 3.97e-01 76.5% 57.6%
4i0xG00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.70 52.0 5.73e-01 94.1% 97.1%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.69 58.0 5.26e-01 91.8% 100.0%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.68 54.0 4.82e-01 83.5% 94.1%
2ra1A01 1.20.58.790 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 47.0 4.48e-01 71.8% 78.6%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.67 53.0 5.21e-01 100.0% 78.0%
2xzmO02 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.67 47.0 5.12e-01 72.9% 97.1%
1xeqB00 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.67 49.0 4.99e-01 78.8% 85.9%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.66 41.0 4.37e-01 94.1% 70.7%
1ailA00 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.66 48.0 5.25e-01 76.5% 95.7%
1z0pA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 53.0 5.66e-01 98.8% 98.6%
1m56C02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.66 56.0 4.29e-01 92.9% 71.9%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.65 56.0 4.88e-01 92.9% 83.2%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.65 54.0 4.29e-01 92.9% 79.2%
2oh3A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 51.0 4.16e-01 82.4% 50.0%
4asvA00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.63 44.0 4.56e-01 72.9% 86.1%
4ap2B01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.63 44.0 3.83e-01 74.1% 61.9%
3k7xA00 1.50.10.20 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.63 47.0 3.10e-01 78.8% 66.6%
1tqgA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.63 52.0 4.88e-01 91.8% 100.0%
3zsuA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.62 52.0 4.69e-01 92.9% 96.6%
4abxA02 6.10.140.1090 Special › Helix non-globular › Helix Hairpins › 0.62 47.0 4.67e-01 92.9% 77.0%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.62 51.0 4.55e-01 91.8% 94.4%
3cwzB01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.62 53.0 4.42e-01 94.1% 82.9%
2wzkA01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.62 45.0 3.91e-01 75.3% 66.1%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.62 56.0 4.86e-01 98.8% 100.0%
1yw0A00 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 56.0 3.97e-01 100.0% 82.3%
6jpaE00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.61 51.0 4.05e-01 100.0% 45.6%
7wf6A01 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.61 51.0 4.35e-01 91.8% 72.7%
4gltA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 55.0 4.96e-01 100.0% 93.0%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 54.0 4.94e-01 98.8% 95.6%
1yz5B00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.60 54.0 3.94e-01 98.8% 62.9%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 53.0 4.95e-01 94.1% 81.4%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 49.0 4.77e-01 97.6% 79.6%
4hteA03 1.10.167.30 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › 0.59 47.0 4.88e-01 85.9% 96.2%
3qavA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 52.0 4.44e-01 100.0% 77.9%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 52.0 4.83e-01 97.6% 81.9%
4hz4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 51.0 4.68e-01 97.6% 91.1%
4dloB02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.58 40.0 3.64e-01 85.9% 53.0%
2au5A00 1.20.120.590 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › EF2947-like 0.56 49.0 4.31e-01 97.6% 82.2%
1gqeA01 1.20.58.410 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor 0.56 50.0 4.55e-01 96.5% 76.1%
1nf1A02 1.10.506.10 Mainly Alpha › Orthogonal Bundle › GTPase Activation - p120GAP; domain 1 › GTPase Activation - p120gap; domain 1 0.56 39.0 3.15e-01 74.1% 65.5%
4od4A02 1.20.120.1780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase 0.55 46.0 4.15e-01 91.8% 91.6%
3ubkB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 48.0 4.27e-01 100.0% 83.2%
2kjgA00 1.20.120.970 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.52 41.0 3.92e-01 87.1% 73.7%
3ljbA00 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.52 45.0 3.39e-01 98.8% 99.1%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3939917 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.73 58.0 4.56e-01 84.7% 99.4%
4950709 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.71 49.0 5.52e-01 95.3% 93.8%
3932021 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.71 58.0 4.03e-01 88.2% 80.4%
4112769 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.70 59.0 5.19e-01 89.4% 96.7%
4181721 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.70 59.0 5.19e-01 91.8% 98.4%
4118417 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.69 58.0 5.06e-01 91.8% 90.8%
3789156 192.29.1.223 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Syntaxin_2 0.69 57.0 4.55e-01 90.6% 92.9%
4994979 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.68 52.0 3.91e-01 96.5% 35.8%
4515233 5059.1.1.18 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UPF0060 0.68 57.0 5.21e-01 91.8% 95.5%
3949247 605.1.1.208 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF6216 0.67 48.0 3.88e-01 96.5% 40.0%
3502048 601.24.1.0 alpha bundles › Four-helical up-and-down bundle › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) 0.67 52.0 5.03e-01 83.5% 97.9%
4247950 4994.1.1.1 alpha duplicates or obligate multimers › EF2458-like › EF2458-like › EF2458-like › DUF1507 0.67 49.0 4.75e-01 77.6% 84.2%
3213478 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.66 53.0 5.34e-01 96.5% 83.5%
5018475 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 58.0 5.15e-01 96.5% 94.2%
3786466 601.1.2.75 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PTPLA 0.65 59.0 4.36e-01 98.8% 91.2%
54592 601.13.1.0 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS 0.65 56.0 4.91e-01 92.9% 84.6%
3974600 601.3.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain 0.65 56.0 4.86e-01 95.3% 84.6%
3715787 603.1.1.98 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 0.64 58.0 4.18e-01 98.8% 86.1%
3706015 603.1.1.6 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.64 58.0 4.26e-01 98.8% 92.1%
4999123 604.12.1.135 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Oxidored_q2 0.64 52.0 4.80e-01 96.5% 69.5%
4018342 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.64 52.0 4.82e-01 89.4% 96.4%
3182496 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.64 49.0 3.13e-01 92.9% 18.4%
143387 601.3.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt 0.63 55.0 5.04e-01 96.5% 94.7%
4022228 109.40.1.2 alpha superhelices › Repetitive alpha hairpins › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › Ctf4_C 0.63 52.0 4.26e-01 97.6% 50.0%
3498232 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.63 56.0 4.24e-01 96.5% 93.2%
5056869 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.63 49.0 3.80e-01 92.9% 40.0%
3707021 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.62 57.0 4.35e-01 100.0% 93.7%
3927737 632.8.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 0.62 51.0 4.91e-01 97.6% 77.9%
3711224 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.62 53.0 4.90e-01 98.8% 74.3%
3667752 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.62 56.0 4.78e-01 97.6% 72.3%
3686422 621.1.1.0 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 0.62 47.0 4.41e-01 81.2% 68.6%
4999454 604.10.1.0 alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac 0.61 55.0 5.12e-01 97.6% 79.8%
4623556 150.3.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine 0.60 43.0 3.51e-01 76.5% 43.6%
3444721 603.1.1.6 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.59 52.0 3.98e-01 97.6% 95.9%
3516461 603.1.1.103 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF29732 0.59 49.0 4.55e-01 91.8% 78.2%
3703129 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 54.0 4.02e-01 100.0% 63.5%
4628639 150.1.1.59 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Coat_F 0.58 48.0 4.65e-01 90.6% 95.8%
3234964 604.7.1.1 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA 0.58 52.0 4.73e-01 96.5% 97.3%
3481122 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 51.0 4.88e-01 96.5% 86.0%
3589591 601.32.1.1 alpha bundles › Four-helical up-and-down bundle › FusB family N-terminal domain › FusB family N-terminal domain › EF-G-binding_N 0.57 45.0 4.62e-01 88.2% 97.5%
4029508 109.4.1.588 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FPL 0.55 48.0 2.97e-01 97.6% 22.4%
3497150 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.54 46.0 3.75e-01 96.5% 62.9%
1268387 604.1.1.6 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_4 0.54 47.0 4.39e-01 98.8% 80.7%
3491182 109.1.1.0 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.52 44.0 3.68e-01 94.1% 68.5%