←Back to structures

VP5

Euk-Vir

Orungo_virus

VP5__YP_009507723__Orungo_virus__40058

Identity

Accession:
YP_009507723 ↗
Protein ID:
VP5
Kingdom:
euk

Quality

70.4 mean pLDDT

Taxonomy

Orthornavirae› Duplornaviricota› Resentoviricetes› Reovirales› Sedoreoviridae› Orbivirus› Orungo_virus

TaxID: 40058

Cluster

View cluster (13 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 351-501
PDB
Domain cluster: rep: VP5__YP_008719914__Mobuck_virus__1408137__D356-507
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00901.25 best Orbi_VP5 213.0 1.00e-62 100.0% 29.6%
D2 medium residues 27-76
PDB
D3 medium residues 103-184_247-274
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00901.25 best Orbi_VP5 55.2 6.70e-15 75.4% 16.0%
CATH (37)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2o8pA00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.68 54.0 4.28e-01 83.6% 52.1%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.67 41.0 4.87e-01 77.3% 90.5%
3u8vA00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.67 37.0 4.25e-01 80.0% 72.3%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.65 48.0 4.75e-01 77.3% 85.5%
5nl6B01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 48.0 4.72e-01 80.0% 82.6%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 50.0 4.20e-01 86.4% 84.7%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 48.0 5.18e-01 80.9% 96.7%
7nmqA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.62 52.0 3.67e-01 91.8% 84.3%
2ap3A00 1.20.120.570 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like 0.62 47.0 3.87e-01 79.1% 56.2%
2a9uA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.62 41.0 3.93e-01 80.9% 58.7%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.61 47.0 4.93e-01 82.7% 94.1%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.61 43.0 4.50e-01 76.4% 79.4%
2l6hA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.60 41.0 3.67e-01 70.0% 80.5%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.59 45.0 4.70e-01 81.8% 86.4%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.59 42.0 4.48e-01 80.0% 86.0%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 45.0 4.35e-01 80.0% 81.1%
1xzpA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.58 45.0 3.94e-01 81.8% 56.0%
1s3qG00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 44.0 3.88e-01 80.0% 79.1%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.57 44.0 4.61e-01 80.9% 87.3%
6nsjA00 1.25.40.600 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › AmiS/UreI transporter 0.57 44.0 3.77e-01 87.3% 50.5%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.56 47.0 4.68e-01 89.1% 100.0%
2q24A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 43.0 3.79e-01 83.6% 85.5%
2wy4A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.56 47.0 4.40e-01 93.6% 92.8%
3chxC00 1.20.1050.50 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Particulate methane monooxygenase subunit c2. Chain: C 0.55 45.0 3.96e-01 88.2% 66.0%
4xpwA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.55 42.0 3.94e-01 80.0% 74.0%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.54 46.0 3.96e-01 94.5% 72.3%
6jpaE00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.54 46.0 4.01e-01 92.7% 87.0%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.54 43.0 4.02e-01 82.7% 69.2%
1cg5B00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 46.0 4.23e-01 92.7% 94.3%
2hjmA01 1.20.120.460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like 0.53 38.0 4.19e-01 85.5% 93.0%
2or0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 40.0 3.37e-01 80.0% 80.6%
4ezbA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.53 38.0 3.79e-01 75.5% 80.3%
8ex5A02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.52 45.0 3.56e-01 96.4% 45.9%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.52 36.0 3.78e-01 84.5% 76.7%
2olpA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 42.0 3.89e-01 93.6% 98.0%
1c02A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.51 43.0 3.78e-01 92.7% 100.0%
3fflA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.50 40.0 3.89e-01 91.8% 75.4%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1721532 3733.1.1.1 ↗ a+b complex topology › Orbivirus outer capsid protein VP5 › Orbivirus outer capsid protein VP5 › Orbivirus outer capsid protein VP5 › Orbi_VP5 0.92 88.0 5.46e-01 100.0% 33.1%
None — 0.71 57.0 4.50e-01 86.4% 72.4%
None — 0.70 54.0 4.09e-01 80.0% 68.6%
3697260 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.68 55.0 4.47e-01 86.4% 85.4%
3517342 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.67 51.0 4.24e-01 79.1% 51.9%
3932846 603.1.1.1 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin 0.67 54.0 4.38e-01 86.4% 83.4%
3375742 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.66 53.0 4.63e-01 85.5% 83.6%
4003906 5057.1.1.0 ↗ alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.66 46.0 4.37e-01 81.8% 60.8%
3188597 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.65 47.0 5.13e-01 82.7% 91.1%
3927597 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.65 50.0 4.84e-01 80.0% 83.3%
4024537 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.65 52.0 4.27e-01 86.4% 88.0%
3706812 603.1.1.17 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.64 51.0 3.85e-01 86.4% 71.1%
3372974 3684.1.1.2 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.64 51.0 3.84e-01 83.6% 97.3%
3219394 633.23.1.14 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › Claudin_3 0.64 53.0 4.56e-01 89.1% 90.0%
3727441 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.63 47.0 3.76e-01 77.3% 49.8%
3923182 174.1.1.43 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.62 53.0 4.77e-01 91.8% 84.0%
3587778 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.62 48.0 4.20e-01 81.8% 93.3%
3463576 3684.1.1.2 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.62 53.0 4.23e-01 93.6% 71.4%
3581266 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.62 47.0 4.77e-01 80.0% 81.8%
4026893 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.61 47.0 3.88e-01 81.8% 48.8%
4029302 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.61 49.0 4.11e-01 86.4% 78.9%
3209632 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.61 44.0 4.46e-01 75.5% 79.1%
3211945 633.23.1.14 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › Claudin_3 0.61 52.0 4.46e-01 91.8% 88.2%
3622094 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.60 51.0 4.53e-01 91.8% 78.1%
4950112 604.5.1.1 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.60 51.0 4.16e-01 91.8% 90.2%
3780807 174.1.1.52 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF27925 0.60 51.0 4.80e-01 91.8% 89.2%
3829773 3684.1.1.2 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.60 48.0 3.77e-01 85.5% 86.7%
3304563 150.1.1.164 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › MENTAL 0.60 49.0 4.27e-01 89.1% 79.4%
3486497 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.59 50.0 4.76e-01 91.8% 96.9%
3783886 109.4.1.109 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sel1 0.59 46.0 3.69e-01 82.7% 48.4%
3298600 174.1.1.45 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › MENTAL 0.59 50.0 4.51e-01 91.8% 91.3%
3530376 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 44.0 4.73e-01 80.0% 92.6%
4979111 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.57 44.0 4.57e-01 82.7% 90.0%
54287 633.10.1.0 ↗ alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.57 48.0 4.72e-01 88.2% 94.8%
5050919 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.57 44.0 4.40e-01 80.9% 89.1%
54292 633.10.1.0 ↗ alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.57 47.0 4.68e-01 88.2% 100.0%
4034363 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.56 43.0 4.31e-01 80.0% 86.4%
5050107 159.1.1.1 ↗ alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › MazG 0.55 39.0 4.15e-01 98.2% 84.2%
3987559 1075.1.2.16 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › DUF1430 0.55 45.0 3.34e-01 91.8% 94.0%
5080053 601.14.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.55 44.0 4.14e-01 85.5% 71.1%
5045405 3684.1.1.0 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.54 44.0 3.81e-01 85.5% 70.3%
4931873 1075.1.1.12 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › CcmB 0.54 45.0 3.56e-01 89.1% 53.8%
3385850 1075.5.1.2 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ 0.54 44.0 3.43e-01 88.2% 70.2%
3473869 7015.1.1.0 ↗ alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.54 44.0 4.04e-01 92.7% 86.5%
3839827 1075.5.1.2 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ 0.52 43.0 3.45e-01 90.9% 85.7%
4387290 1075.5.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.52 44.0 3.54e-01 92.7% 95.0%
3480464 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 44.0 3.48e-01 96.4% 49.8%
3317397 603.1.1.17 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.51 40.0 3.29e-01 85.5% 77.1%
3782277 601.1.2.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.50 46.0 3.78e-01 100.0% 56.8%