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VP6

Euk-Vir

Rotavirus_I

VP6__YP_009130678__Rotavirus_I__1637496

Identity

Accession:
YP_009130678 ↗
Protein ID:
VP6
Kingdom:
euk

Quality

71.1 mean pLDDT

Taxonomy

Orthornavirae› Duplornaviricota› Resentoviricetes› Reovirales› Sedoreoviridae› Rotavirus› Rotavirus_I

TaxID: 1637496

Cluster

View cluster (4 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-124
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF25657.2 best Rota_VP6 198.1 3.10e-58 100.0% 31.0%
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1qhdA02 1.10.1350.10 Mainly Alpha › Orthogonal Bundle › Viral capsid alpha domain › Viral capsid alpha domain 0.73 66.0 5.41e-01 100.0% 55.9%
2l7nA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.63 48.0 4.36e-01 80.3% 71.4%
3dyjA02 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.62 47.0 4.36e-01 77.9% 80.1%
2xsbA02 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.61 43.0 4.04e-01 73.0% 93.3%
5jc3A02 1.20.1320.30 Mainly Alpha › Up-down Bundle › phosphoenolpyruvate carboxylase, domain 3 › 0.58 30.0 3.03e-01 94.3% 48.4%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.56 43.0 4.16e-01 82.0% 81.7%
3n5fA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.53 37.0 2.79e-01 71.3% 99.3%
4mi7A00 3.90.70.170 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.52 37.0 3.73e-01 96.7% 72.6%
1r3nG01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.52 39.0 2.97e-01 80.3% 96.8%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1503850 617.1.1.2 ↗ alpha bundles › A virus capsid protein alpha-helical domain › A virus capsid protein alpha-helical domain › A virus capsid protein alpha-helical domain › Rota_Capsid_VP6 0.74 67.0 6.29e-01 100.0% 85.8%
5024994 4163.1.1.0 ↗ alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like 0.59 37.0 3.74e-01 90.2% 62.5%
3255243 601.1.2.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.59 45.0 4.56e-01 79.5% 98.3%
4184794 601.1.1.7 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B 0.58 45.0 4.21e-01 81.1% 80.7%
3921484 5001.1.1.3 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 0.58 41.0 3.25e-01 73.0% 82.4%
3930303 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 45.0 3.16e-01 82.8% 33.7%
3522706 109.4.1.1452 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_Maestro, HEAT_Maestro_2 0.55 39.0 3.01e-01 78.7% 31.8%
4191506 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 47.0 3.79e-01 95.1% 90.0%
3929429 5050.1.1.31 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › SLC52_ribofla_tr 0.50 41.0 3.49e-01 88.5% 59.5%
D2 high residues 150-330
PDB
Domain cluster: rep: major_inner_capsid_protein__YP_392512__Rotavirus_C__36427__D161-330
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF25657.2 best Rota_VP6 259.4 7.70e-77 100.0% 45.4%
CATH (47)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1qhdA01 2.60.120.170 Mainly Beta › Sandwich › Jelly Rolls › 0.77 69.0 7.12e-01 93.4% 100.0%
4e2oA02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.70 33.0 4.70e-01 93.9% 93.2%
4dzgA00 2.60.120.380 Mainly Beta › Sandwich › Jelly Rolls › 0.70 43.0 5.38e-01 88.4% 99.1%
4nzfD02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.68 34.0 4.64e-01 95.0% 94.4%
1m1sA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.68 34.0 4.21e-01 97.2% 77.1%
1wzlA04 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.68 32.0 4.59e-01 91.2% 97.6%
3w5mA06 2.60.420.10 Mainly Beta › Sandwich › Maltose phosphorylase, domain 3 › Maltose phosphorylase, domain 3 0.67 33.0 4.32e-01 92.8% 83.0%
1uasA02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.67 33.0 4.57e-01 93.9% 96.6%
1o5uA00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.66 28.0 3.90e-01 78.5% 78.4%
3rnsA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.66 34.0 4.30e-01 84.5% 82.4%
5z0uA03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.66 32.0 4.39e-01 91.2% 92.2%
2vecA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.66 36.0 4.72e-01 92.3% 94.2%
2oyzA00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.66 34.0 4.58e-01 93.4% 95.7%
3hqxA00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.66 35.0 4.48e-01 92.8% 88.6%
2wpgA04 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.65 29.0 4.29e-01 92.3% 97.3%
3a21A02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.65 33.0 4.50e-01 92.3% 94.5%
2wcoA03 2.60.220.10 Mainly Beta › Sandwich › Chondroitinase Ac; Chain A, domain 3 › Polysaccharide lyase family 8-like, C-terminal 0.65 35.0 4.29e-01 94.5% 81.7%
3h7jA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.64 35.0 4.25e-01 93.9% 81.6%
1pmiA03 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.64 38.0 4.60e-01 96.1% 89.1%
3eo6A00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.64 33.0 4.19e-01 92.8% 84.0%
3kl0D01 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.63 36.0 4.57e-01 92.8% 94.3%
1sfpA00 2.60.120.290 Mainly Beta › Sandwich › Jelly Rolls › Spermadhesin, CUB domain 0.62 38.0 4.72e-01 94.5% 99.1%
1j0hA04 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.62 31.0 4.25e-01 93.4% 98.8%
3es4A00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.61 35.0 4.22e-01 95.0% 86.2%
4d6gA03 2.60.220.10 Mainly Beta › Sandwich › Chondroitinase Ac; Chain A, domain 3 › Polysaccharide lyase family 8-like, C-terminal 0.60 39.0 4.59e-01 95.0% 91.5%
2e8yA04 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.60 31.0 4.20e-01 72.4% 98.9%
6l4cA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.60 37.0 3.74e-01 95.0% 60.3%
1sefA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.60 35.0 4.07e-01 95.0% 79.4%
3h8uA00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.59 33.0 3.95e-01 92.8% 79.5%
1vcaA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 31.0 3.83e-01 93.4% 80.9%
2bnmA02 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.58 35.0 4.15e-01 93.4% 88.3%
4p02B01 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.57 41.0 4.64e-01 96.1% 99.2%
1j3qB00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.57 42.0 4.21e-01 93.9% 74.3%
2c4xA02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.56 45.0 4.88e-01 99.4% 99.4%
3isyA00 2.60.40.2360 Mainly Beta › Sandwich › Immunoglobulin-like › Intracellular proteinase inhibitor BsuPI 0.56 34.0 4.00e-01 95.6% 89.7%
4hslA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.56 31.0 3.30e-01 92.8% 58.4%
3a5vA02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.55 32.0 3.97e-01 75.1% 100.0%
2vrsA03 2.60.90.40 Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › 0.54 39.0 4.44e-01 77.9% 100.0%
2a74A05 2.60.40.1930 Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain 0.54 32.0 4.02e-01 82.9% 98.1%
1gxeA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 35.0 4.06e-01 98.9% 90.0%
4es8B01 2.60.120.1240 Mainly Beta › Sandwich › Jelly Rolls › 0.54 50.0 4.87e-01 99.4% 100.0%
1ajwA00 2.70.50.30 Mainly Beta › Distorted Sandwich › Coagulation Factor XIII; Chain A, domain 1 › Coagulation Factor XIII, subunit A, domain 1 0.53 36.0 3.89e-01 96.7% 84.1%
3es1A02 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.53 34.0 3.97e-01 93.9% 92.1%
2f4pA00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.52 34.0 3.82e-01 97.8% 87.3%
3zghA00 2.60.40.3400 Mainly Beta › Sandwich › Immunoglobulin-like › 0.51 42.0 4.27e-01 87.8% 89.3%
2xsgB01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.51 38.0 3.23e-01 75.7% 82.5%
1ju3A02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.51 45.0 4.28e-01 97.2% 100.0%
ECOD (43)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1263 10.5.1.3 ↗ beta sandwiches › jelly-roll › Viral protein domain › Viral protein domain › Rota_Capsid_VP6 0.78 74.0 7.43e-01 100.0% 100.0%
4971702 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.76 39.0 5.46e-01 76.2% 100.0%
5005781 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.73 39.0 4.92e-01 77.9% 87.6%
5009359 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.71 38.0 4.77e-01 78.5% 84.5%
4648192 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.71 39.0 4.75e-01 96.1% 82.6%
1806777 12.1.1.53 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Alpha-amylase_C_2 0.70 32.0 4.62e-01 93.4% 92.9%
3857934 10.32.1.186 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Androglobin_V 0.70 38.0 4.95e-01 97.8% 93.2%
5028186 10.1.2.183 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) › PPC 0.68 40.0 5.14e-01 90.1% 99.0%
5044901 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.68 41.0 5.10e-01 97.8% 93.9%
3268021 12.1.1.35 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Melibiase_C 0.68 35.0 4.71e-01 93.4% 93.7%
2443962 12.6.1.3 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related › Bac_rhamnosid_C 0.67 34.0 4.35e-01 92.8% 82.4%
1412508 12.1.1.35 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Melibiase_C 0.66 34.0 4.61e-01 93.9% 96.7%
1280305 10.12.1.59 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › Pirin_C_2 0.66 36.0 4.86e-01 92.3% 100.0%
3974326 10.12.1.0 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.66 33.0 3.90e-01 97.8% 68.0%
135454 10.12.1.35 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › Ppnp 0.66 35.0 4.48e-01 92.8% 88.6%
3966668 10.12.1.0 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.65 34.0 4.59e-01 94.5% 96.8%
4682208 12.2.1.1 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Hyaluronate lyase-like, C-terminal domain › Hyaluronate lyase-like, C-terminal domain › Lyase_8_C 0.65 35.0 4.29e-01 94.5% 80.0%
4963436 10.12.1.39 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › Cupin_2 0.65 36.0 4.45e-01 94.5% 87.3%
1870637 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.65 34.0 4.48e-01 93.4% 94.7%
4029608 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.64 38.0 4.78e-01 82.3% 96.4%
4038262 10.12.1.35 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › Ppnp 0.64 34.0 4.42e-01 93.9% 92.9%
4437824 10.12.1.35 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › Ppnp 0.63 33.0 4.31e-01 93.4% 90.0%
4996579 10.12.1.39 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › Cupin_2 0.63 33.0 4.15e-01 93.4% 83.3%
5083765 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.63 36.0 4.19e-01 99.4% 78.5%
5068910 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.62 43.0 4.96e-01 93.9% 95.6%
3192481 12.6.1.3 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related › Bac_rhamnosid_C 0.62 32.0 4.10e-01 94.5% 86.4%
5067959 10.12.1.39 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › Cupin_2 0.60 33.0 3.98e-01 81.8% 80.9%
4132858 11.1.1.97 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set 0.60 32.0 4.02e-01 96.7% 85.7%
3891591 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.60 39.0 4.75e-01 92.3% 100.0%
4030176 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.59 45.0 4.83e-01 79.0% 98.1%
2448132 10.12.1.39 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › Cupin_2 0.57 35.0 4.32e-01 100.0% 99.1%
3730887 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.56 45.0 4.85e-01 97.8% 100.0%
4999960 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 33.0 3.97e-01 94.5% 91.8%
3979066 10.12.1.0 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.55 36.0 3.42e-01 95.0% 55.7%
3307787 207.1.1.43 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_3 0.53 34.0 2.47e-01 91.7% 21.2%
3498711 10.32.1.6 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › P_proprotein 0.53 46.0 4.69e-01 100.0% 94.4%
3828450 11.1.1.51 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › LEA_2 0.53 37.0 3.63e-01 99.4% 63.8%
3627122 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 31.0 3.43e-01 90.6% 69.3%
5055269 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 37.0 4.21e-01 98.3% 100.0%
5055872 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.53 43.0 4.60e-01 95.0% 99.4%
3540693 11.1.1.18 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › LTD 0.52 30.0 3.61e-01 93.4% 88.2%
3947237 10.12.1.0 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.52 37.0 3.63e-01 96.7% 67.7%
2048191 10.1.1.54 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Sialidase-like_CBM 0.51 46.0 4.46e-01 98.3% 99.0%
D3 high residues 353-393
PDB