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VP6
Euk-VirOrbivirus_SX-2017a
VP6__YP_009345884__Orbivirus_SX-2017a__1955493
Identity
- Accession:
- YP_009345884 ↗
- Protein ID:
- VP6
- Kingdom:
- euk
Quality
72.8
mean pLDDT
Cluster
View cluster (13 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-10_358-513
Domain cluster:
rep: VP5__YP_008719914__Mobuck_virus__1408137__D356-507
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00901.25 best | Orbi_VP5 | 239.4 | 9.80e-71 | 99.4% | 31.4% |
D2
medium
residues 95-185_237-278_306-357
Domain cluster:
rep: VP5__YP_009507710__Lebombo_virus__40057__D103-181_236-275_307-348
Pfam (3)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00901.25 best | Orbi_VP5 | 60.8 | 1.40e-16 | 49.7% | 17.9% |
| PF00901.25 | Orbi_VP5 | 27.7 | 1.40e-06 | 29.7% | 10.3% |
| PF00901.25 | Orbi_VP5 | 50.6 | 1.70e-13 | 24.3% | 8.5% |
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3ctwB00 | 1.10.8.930 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 | 0.64 | 26.0 | 3.25e-01 | 70.3% | 57.5% |
| 4o6yB00 | 1.20.120.1770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.60 | 42.0 | 4.07e-01 | 71.4% | 77.3% |
| 7d3uC01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 33.0 | 4.21e-01 | 80.5% | 93.5% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.59 | 30.0 | 3.90e-01 | 81.1% | 84.9% |
| 5nl6A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 31.0 | 3.92e-01 | 83.8% | 88.0% |
| 1dvkA00 | 1.20.940.10 | Mainly Alpha › Up-down Bundle › RNA Binding Protein, Prp18; Chain A › Functional domain of the splicing factor Prp18 | 0.57 | 31.0 | 3.39e-01 | 93.5% | 63.1% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.57 | 36.0 | 3.87e-01 | 82.2% | 71.3% |
| 3terA00 | 1.10.287.3550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 28.0 | 3.44e-01 | 73.0% | 80.7% |
| 6m20C01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 46.0 | 3.44e-01 | 97.3% | 87.1% |
| 7dl9B02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.51 | 36.0 | 3.52e-01 | 71.9% | 69.5% |
| 2ptqA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.50 | 38.0 | 3.34e-01 | 77.8% | 83.1% |
| 8ex5A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.50 | 42.0 | 3.97e-01 | 88.1% | 75.7% |
ECOD (42)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1721532 | 3733.1.1.1 ↗ | a+b complex topology › Orbivirus outer capsid protein VP5 › Orbivirus outer capsid protein VP5 › Orbivirus outer capsid protein VP5 › Orbi_VP5 | 0.91 | 88.0 | 6.10e-01 | 100.0% | 50.8% |
| 4368090 | 3565.1.1.1 ↗ | alpha bundles › Na/H pumping membrane integral pyrophosphatase › Na/H pumping membrane integral pyrophosphatase › Na/H pumping membrane integral pyrophosphatase › H_PPase | 0.61 | 48.0 | 3.25e-01 | 82.2% | 96.4% |
| 4637254 | 5050.1.1.25 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TLC | 0.60 | 49.0 | 4.47e-01 | 85.9% | 74.3% |
| 3269680 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.59 | 49.0 | 4.34e-01 | 88.6% | 83.3% |
| 3795092 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.58 | 36.0 | 4.12e-01 | 83.8% | 83.0% |
| 2987615 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.58 | 48.0 | 4.54e-01 | 88.1% | 77.9% |
| 3731715 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.58 | 48.0 | 4.59e-01 | 87.0% | 88.1% |
| 4081382 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.57 | 50.0 | 4.61e-01 | 92.4% | 80.9% |
| 3184682 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 47.0 | 4.29e-01 | 87.6% | 80.9% |
| 3534773 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 49.0 | 4.71e-01 | 94.6% | 85.1% |
| 4282274 | 5050.1.1.25 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TLC | 0.56 | 48.0 | 4.42e-01 | 93.5% | 78.0% |
| 3726701 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 46.0 | 4.19e-01 | 87.6% | 76.4% |
| 3621551 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.56 | 36.0 | 3.87e-01 | 82.7% | 74.4% |
| 3921512 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.55 | 46.0 | 4.14e-01 | 88.6% | 78.5% |
| 3822053 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.55 | 47.0 | 4.14e-01 | 90.3% | 74.0% |
| 3921752 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.55 | 49.0 | 4.50e-01 | 94.6% | 82.1% |
| 3829168 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.55 | 43.0 | 4.07e-01 | 82.2% | 89.8% |
| 3309359 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.54 | 45.0 | 3.71e-01 | 88.1% | 64.8% |
| 3188194 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 46.0 | 4.32e-01 | 90.8% | 76.9% |
| 3855979 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.54 | 46.0 | 4.21e-01 | 91.4% | 80.4% |
| 4551983 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.54 | 45.0 | 3.97e-01 | 89.7% | 76.4% |
| 3802401 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.54 | 46.0 | 4.36e-01 | 90.3% | 88.4% |
| 3537334 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 47.0 | 4.30e-01 | 94.1% | 72.4% |
| 3936764 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.53 | 44.0 | 4.19e-01 | 87.0% | 84.1% |
| 3412831 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.53 | 38.0 | 4.16e-01 | 89.7% | 91.3% |
| 4019453 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 44.0 | 4.03e-01 | 90.8% | 93.6% |
| 2886244 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.52 | 45.0 | 4.15e-01 | 92.4% | 80.2% |
| 4456477 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.52 | 36.0 | 3.75e-01 | 89.7% | 73.7% |
| 3912405 | 109.4.1.219 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TINF2_N | 0.52 | 36.0 | 3.48e-01 | 78.4% | 62.0% |
| 3727507 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 45.0 | 4.15e-01 | 91.9% | 80.9% |
| 3499672 | 1203.1.2.13 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › Ribophorin_II | 0.52 | 34.0 | 3.72e-01 | 86.5% | 79.3% |
| 3788611 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 41.0 | 3.92e-01 | 80.5% | 90.5% |
| 3733327 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 44.0 | 4.07e-01 | 90.3% | 71.5% |
| 3684994 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.52 | 45.0 | 4.15e-01 | 94.6% | 82.9% |
| 3933742 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.52 | 36.0 | 3.89e-01 | 90.3% | 83.1% |
| 4442857 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 41.0 | 4.06e-01 | 91.4% | 79.0% |
| 4262528 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 40.0 | 3.85e-01 | 84.9% | 71.7% |
| 4084468 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.51 | 36.0 | 3.09e-01 | 71.9% | 94.6% |
| 3372974 | 3684.1.1.2 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 | 0.51 | 42.0 | 3.73e-01 | 87.0% | 94.2% |
| 3192658 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.50 | 44.0 | 4.16e-01 | 94.6% | 84.4% |
| 3952344 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.50 | 42.0 | 4.00e-01 | 89.2% | 80.9% |
| 3916865 | 109.4.1.117 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › STAG,SCD | 0.50 | 39.0 | 3.46e-01 | 86.5% | 56.9% |
D3
medium
residues 186-236_279-305