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XRN1_5-3_exonuclease

Euk-Vir

Marseillevirus_marseillevirus

XRN1_5-3_exonuclease__YP_003407051__Marseillevirus_marseillevirus__694581

Identity

Accession:
YP_003407051 ↗
Protein ID:
XRN1_5-3_exonuclease
Kingdom:
euk

Quality

72.9 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Marseilleviridae› Marseillevirus› Marseillevirus_marseillevirus

TaxID: 694581

Cluster

View cluster (15 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 236-398
PDB
Domain cluster: rep: conserved_XRN1_5-3_exoribonuclease__YP_009094786__Melbournevirus__1560514__D266-396
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF17846.7 best XRN_M 24.2 2.30e-05 61.4% 20.0%
PF17846.7 XRN_M 36.8 3.50e-09 50.3% 13.2%
D2 high residues 414-485
PDB
D3 medium residues 17-37_87-120_138-225
PDB
Domain cluster: rep: Hypothetical_protein_SPPV_50__NP_659626__Sheeppox_virus__10266__D1-82_143-236
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF03159.25 best XRN_N 44.4 1.90e-11 55.9% 27.8%
PF03159.25 XRN_N 31.9 1.30e-07 28.7% 12.9%
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3pieC01 3.40.50.12390 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.78 75.0 5.91e-01 100.0% 63.5%
3zdbA01 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.67 59.0 5.69e-01 91.6% 99.4%
1tfrA01 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.66 57.0 4.97e-01 90.2% 77.2%
1xo1A02 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.66 57.0 5.54e-01 91.6% 83.6%
1mjhB00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.64 52.0 5.25e-01 85.3% 98.6%
2wteA01 3.40.50.11700 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.63 54.0 5.51e-01 90.9% 98.6%
1dnpA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.62 51.0 5.37e-01 87.4% 100.0%
3s3tA00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.61 50.0 5.07e-01 87.4% 97.9%
2gm3A00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.60 49.0 4.80e-01 86.7% 94.8%
2bmuB00 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.59 51.0 4.36e-01 92.3% 100.0%
2jaxA02 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.59 48.0 4.96e-01 86.0% 99.3%
2dumC00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.59 49.0 4.93e-01 89.5% 97.9%
3hdvB00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.59 40.0 4.23e-01 89.5% 78.6%
4wnyA00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.58 48.0 4.95e-01 86.0% 97.7%
3loqA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.58 48.0 4.89e-01 89.5% 97.2%
4gx0B04 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 42.0 4.41e-01 91.6% 83.2%
7lzaA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 38.0 4.14e-01 88.8% 82.2%
3lteD00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 39.0 4.20e-01 89.5% 81.3%
4ru1A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 41.0 4.14e-01 90.9% 73.6%
4zjpA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.56 42.0 4.26e-01 91.6% 77.1%
5ix8A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.56 43.0 4.15e-01 91.6% 71.7%
3fwzA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 42.0 4.32e-01 90.2% 81.4%
7x0hC01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.56 41.0 4.25e-01 90.9% 81.0%
3c85A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 43.0 4.25e-01 90.2% 77.3%
3u80A00 3.40.50.9100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dehydroquinase, class II 0.56 39.0 4.09e-01 82.5% 80.3%
2h3hA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.56 42.0 4.19e-01 79.0% 97.3%
5t3yA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 38.0 4.03e-01 90.9% 80.0%
3d02A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 42.0 4.20e-01 79.7% 98.0%
2funD00 3.40.50.1460 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 47.0 3.97e-01 93.0% 96.3%
3cs3A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 45.0 4.61e-01 90.9% 91.3%
3gbvA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 38.0 3.89e-01 89.5% 72.9%
2ah5A01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.55 46.0 4.67e-01 91.6% 98.6%
2p11A01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.54 45.0 4.57e-01 90.2% 95.9%
4jgiB02 3.40.50.280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain 0.54 38.0 4.05e-01 91.6% 82.5%
4xt6A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.54 49.0 4.14e-01 100.0% 87.3%
4y9tA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.54 43.0 4.03e-01 87.4% 69.3%
3cr8C02 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.53 43.0 3.87e-01 87.4% 68.2%
1u9jA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 45.0 3.74e-01 92.3% 88.5%
3bh0A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 45.0 3.64e-01 95.1% 81.7%
2rjoA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 40.0 3.81e-01 90.2% 68.2%
3b48F00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.51 42.0 4.39e-01 88.8% 93.3%
4p98A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 40.0 4.03e-01 83.2% 88.2%
2rjoA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 41.0 4.11e-01 86.0% 97.3%
3hcwA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.50 43.0 4.38e-01 97.2% 93.7%
ECOD (70)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3300817 2006.1.4.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.92 89.0 6.47e-01 100.0% 83.3%
3595159 2006.1.4.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.92 85.0 6.94e-01 96.5% 93.3%
4628515 2006.1.4.5 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XRN_N 0.91 87.0 6.74e-01 98.6% 94.2%
4443696 2006.1.4.5 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XRN_N 0.91 88.0 6.39e-01 100.0% 83.6%
None — 0.91 86.0 6.47e-01 97.9% 94.7%
3400646 2006.1.4.5 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XRN_N 0.91 87.0 6.49e-01 100.0% 93.3%
3276794 2006.1.4.5 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XRN_N 0.90 85.0 6.77e-01 97.9% 93.7%
3294273 2006.1.4.5 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XRN_N 0.90 87.0 6.77e-01 100.0% 91.1%
4027656 2006.1.4.5 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XRN_N 0.90 84.0 6.87e-01 97.9% 93.8%
3716209 2006.1.4.5 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XRN_N 0.88 83.0 5.93e-01 97.9% 70.0%
3251911 2006.1.4.5 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XRN_N 0.87 83.0 7.01e-01 100.0% 92.3%
4031881 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.71 62.0 5.73e-01 91.6% 93.7%
4165496 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.71 62.0 5.66e-01 92.3% 89.7%
4322588 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.71 61.0 5.58e-01 90.2% 90.6%
4238071 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.71 61.0 5.67e-01 90.9% 95.4%
3942272 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.71 61.0 5.77e-01 91.6% 96.5%
4157264 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.70 61.0 5.63e-01 92.3% 94.4%
4031817 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.70 61.0 5.75e-01 92.3% 95.9%
4040391 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.70 62.0 5.69e-01 93.7% 97.2%
3261281 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.69 61.0 5.72e-01 92.3% 95.2%
4136793 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.69 59.0 5.13e-01 90.2% 81.0%
4299585 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.69 60.0 5.47e-01 92.3% 86.5%
3964138 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.68 59.0 5.45e-01 90.9% 87.8%
3808902 2006.1.4.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I 0.68 63.0 5.84e-01 100.0% 91.1%
4125023 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.68 59.0 5.52e-01 90.9% 94.7%
4995752 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.68 59.0 5.60e-01 91.6% 97.0%
4324598 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.68 59.0 5.33e-01 91.6% 84.3%
3969358 2006.1.4.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.67 58.0 5.58e-01 90.2% 97.5%
2074443 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.67 58.0 5.44e-01 90.9% 94.8%
3387660 2006.1.4.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.67 59.0 5.51e-01 92.3% 94.1%
3816414 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.65 55.0 5.72e-01 90.2% 99.3%
3258855 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.64 50.0 5.00e-01 81.1% 99.3%
5000538 2006.1.4.3 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.63 54.0 5.60e-01 92.3% 96.2%
3949665 2006.1.4.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.62 53.0 4.96e-01 89.5% 91.2%
5058649 7514.1.1.1 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › NAD_binding_1 0.61 54.0 5.47e-01 95.8% 96.4%
3837240 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.61 53.0 4.96e-01 92.3% 87.4%
3474702 2006.1.4.11 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PRORP 0.61 51.0 4.66e-01 88.8% 74.7%
3304144 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.61 53.0 4.98e-01 92.3% 94.1%
4955036 7514.1.1.8 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › DHODB_Fe-S_bind 0.61 54.0 4.94e-01 96.5% 83.1%
3261439 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.61 50.0 4.71e-01 86.7% 98.2%
4931387 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.61 49.0 4.91e-01 85.3% 98.6%
3262396 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.61 49.0 4.83e-01 86.0% 95.5%
3331148 2006.1.4.3 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.60 53.0 4.92e-01 93.7% 88.9%
3352482 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.60 51.0 4.90e-01 89.5% 100.0%
3958881 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.60 47.0 4.72e-01 81.8% 97.9%
4931780 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.60 49.0 4.72e-01 87.4% 88.5%
4031886 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.60 46.0 4.76e-01 80.4% 100.0%
3741630 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.60 49.0 4.59e-01 86.0% 100.0%
4034184 2007.1.3.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.60 39.0 4.10e-01 91.6% 72.3%
5000511 2006.1.4.3 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.58 51.0 4.91e-01 93.7% 82.3%
4938376 2003.1.1.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N 0.58 43.0 4.47e-01 90.2% 81.5%
4986482 2003.1.1.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N 0.58 45.0 4.82e-01 90.9% 95.8%
3603404 2003.1.1.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N 0.58 44.0 4.26e-01 90.2% 69.7%
5081666 2003.1.1.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N 0.57 44.0 4.75e-01 90.2% 95.8%
363655 2007.1.3.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.57 37.0 4.02e-01 90.9% 77.0%
5060318 7597.1.1.0 ↗ a/b three-layered sandwiches › Endolysin C-terminal domain › Endolysin C-terminal domain › Endolysin C-terminal domain 0.57 37.0 4.31e-01 88.1% 93.0%
4981516 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.57 50.0 5.00e-01 95.1% 100.0%
4988572 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.57 47.0 4.70e-01 88.1% 100.0%
4961347 2007.1.14.6 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › CbiX 0.57 39.0 4.49e-01 86.7% 99.0%
3672808 2007.1.3.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.57 38.0 4.04e-01 83.9% 77.6%
5019229 2003.1.1.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N 0.56 43.0 4.32e-01 90.9% 79.3%
4932381 2006.1.4.13 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN_9 0.56 45.0 4.77e-01 83.9% 100.0%
4989682 2006.1.4.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.56 45.0 4.67e-01 84.6% 99.2%
4935187 2003.1.1.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N 0.56 42.0 4.27e-01 92.3% 80.0%
4083483 2007.1.14.3 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › Ferrochelatase 0.55 44.0 4.31e-01 86.0% 98.1%
5027900 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.54 47.0 4.63e-01 92.3% 91.3%
4930416 2003.1.1.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N 0.54 38.0 3.99e-01 91.6% 80.0%
3673754 2004.1.1.105 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinase-PPPase 0.53 36.0 3.77e-01 85.3% 74.1%
5033548 2007.1.3.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.51 40.0 3.73e-01 81.8% 81.1%
3266028 7590.1.1.0 ↗ a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs 0.51 39.0 4.23e-01 92.3% 95.8%
D4 medium residues 38-86_121-137
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3i4uA01 1.20.120.1080 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.64 41.0 3.63e-01 86.4% 45.4%
3l8kA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.60 47.0 3.21e-01 83.3% 47.0%
4i9oA00 1.10.246.20 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Coactivator CBP, KIX domain 0.58 41.0 3.87e-01 74.2% 61.5%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.57 41.0 3.77e-01 74.2% 74.7%
2mabA00 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.55 47.0 3.99e-01 95.5% 59.6%
3ppbA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 45.0 3.29e-01 100.0% 53.7%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4541653 4970.1.1.0 ↗ alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.65 45.0 4.08e-01 74.2% 60.0%
3955584 191.1.1.48 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_46 0.63 45.0 3.36e-01 74.2% 31.6%
3519421 2498.1.1.62 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M76 0.63 58.0 4.20e-01 100.0% 38.8%
3912082 2008.1.1.84 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Rab15_effector 0.60 49.0 3.44e-01 90.9% 73.4%
3597723 7579.1.1.0 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.58 51.0 3.35e-01 98.5% 36.6%
3742581 6147.1.1.2 ↗ alpha arrays › C-terminal domain of Dbr1 › C-terminal domain of Dbr1 › C-terminal domain of Dbr1 › DBR1 0.56 40.0 3.56e-01 74.2% 52.6%
3825797 132.1.1.1 ↗ alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding 0.55 37.0 3.34e-01 71.2% 77.0%
3416386 621.1.1.0 ↗ alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 0.55 49.0 4.61e-01 98.5% 86.3%
3392146 7073.1.1.1 ↗ alpha arrays › C-terminal domain of Malic enzyme › C-terminal domain of Malic enzyme › C-terminal domain of Malic enzyme › Malic_M 0.54 37.0 3.17e-01 71.2% 44.8%