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adenylosuccinate_synthetase

Euk-Vir

Pithovirus_sibericum

adenylosuccinate_synthetase__YP_009000992__Pithovirus_sibericum__1450746

Identity

Accession:
YP_009000992 ↗
Protein ID:
adenylosuccinate_synthetase
Kingdom:
euk

Quality

70.2 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Pithoviridae› Alphapithovirus› Pithovirus_sibericum

TaxID: 1450746

Cluster

View cluster (7 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-109_198-265
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00709.28 best Adenylsucc_synt 104.4 8.70e-30 61.9% 24.0%
PF00709.28 Adenylsucc_synt 67.6 1.30e-18 39.3% 15.6%
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1adeA01 3.40.440.10 Alpha Beta › 3-Layer(aba) Sandwich › Adenylosuccinate Synthetase; Chain A, domain 1 › Adenylosuccinate Synthetase, subunit A, domain 1 0.84 76.0 7.81e-01 99.4% 98.8%
3cwqA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.71 40.0 3.83e-01 100.0% 47.3%
5l3qA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.67 46.0 4.32e-01 100.0% 57.8%
1zu4A02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 47.0 4.33e-01 100.0% 59.2%
4c12A03 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.63 48.0 5.02e-01 96.0% 87.3%
2bdtA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 38.0 3.87e-01 100.0% 62.0%
1cqxA03 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.60 44.0 4.74e-01 100.0% 90.8%
1fpzC00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.59 44.0 4.43e-01 97.7% 74.7%
2esbA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.59 39.0 4.03e-01 98.8% 70.4%
2g6zA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.58 38.0 4.15e-01 99.4% 77.6%
3e2dA01 3.40.720.10 Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A 0.58 53.0 4.12e-01 100.0% 81.6%
2zpaA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 40.0 4.49e-01 100.0% 89.7%
4d3pA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.58 38.0 4.14e-01 100.0% 78.2%
1xjcA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 32.0 3.49e-01 100.0% 63.9%
3nwpA00 3.40.50.1360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 51.0 4.61e-01 97.7% 96.1%
6x6aA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 40.0 3.40e-01 72.3% 78.6%
1nijA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 39.0 3.78e-01 100.0% 62.2%
3euaF01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.55 35.0 3.66e-01 71.7% 68.6%
3io3A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 48.0 4.35e-01 93.1% 81.3%
4bgvA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 44.0 4.75e-01 85.5% 100.0%
2om6A01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.53 41.0 4.36e-01 100.0% 91.5%
2amlA02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.53 36.0 3.86e-01 96.0% 80.3%
4ii2A04 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 43.0 4.00e-01 87.9% 85.8%
2bpoA04 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.53 45.0 4.68e-01 92.5% 98.8%
5dn8A02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 35.0 3.61e-01 71.7% 70.6%
1k2wA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 43.0 3.76e-01 87.3% 96.1%
3e3mA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 39.0 4.19e-01 95.4% 91.7%
3bxpB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.52 37.0 3.25e-01 72.3% 85.5%
4kq9A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 39.0 3.71e-01 95.4% 67.0%
4w7sA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 45.0 4.38e-01 100.0% 86.0%
1bwpA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.52 41.0 3.84e-01 93.6% 67.9%
1aukA01 3.40.720.10 Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A 0.51 46.0 3.62e-01 100.0% 74.7%
2p4dA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.51 38.0 3.89e-01 96.5% 80.4%
1tzbA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.51 34.0 3.58e-01 96.0% 72.2%
2cvhA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 44.0 4.15e-01 93.6% 88.3%
2ebfX04 3.40.50.11550 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 44.0 3.89e-01 100.0% 63.6%
3aawC01 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.51 42.0 3.90e-01 100.0% 68.3%
1rliD00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.51 39.0 3.95e-01 93.6% 81.5%
2j16A00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.50 33.0 3.66e-01 95.4% 85.0%
ECOD (51)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3495929 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.87 84.0 6.02e-01 100.0% 60.2%
4477211 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.86 83.0 5.99e-01 100.0% 61.9%
4472870 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.86 83.0 5.87e-01 100.0% 61.6%
4942154 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.86 83.0 6.11e-01 100.0% 56.9%
4353609 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.86 83.0 5.89e-01 100.0% 60.0%
1883519 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.85 82.0 5.91e-01 100.0% 61.5%
5056176 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.85 82.0 6.24e-01 100.0% 60.3%
4036208 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.85 81.0 5.85e-01 100.0% 61.4%
3599285 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.85 81.0 5.48e-01 100.0% 47.7%
4624820 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.85 81.0 5.41e-01 100.0% 50.4%
4036504 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.85 82.0 6.33e-01 100.0% 64.5%
4258627 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.85 81.0 5.83e-01 100.0% 60.9%
4933558 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.84 82.0 5.87e-01 100.0% 61.2%
4180893 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.84 82.0 5.81e-01 100.0% 58.9%
4639006 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.84 79.0 6.68e-01 96.5% 98.8%
4203696 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.84 81.0 5.73e-01 100.0% 60.0%
3066560 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.84 81.0 6.09e-01 100.0% 64.2%
4291957 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.84 81.0 5.75e-01 100.0% 57.5%
4158935 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.83 78.0 5.68e-01 98.3% 63.2%
5024558 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.83 80.0 5.71e-01 100.0% 60.7%
4644713 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.82 79.0 5.73e-01 100.0% 62.7%
4259208 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.80 75.0 5.49e-01 97.7% 61.8%
2772441 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.78 75.0 5.75e-01 100.0% 63.4%
5021540 7550.1.1.0 ↗ a/b three-layered sandwiches › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain 0.68 40.0 5.09e-01 100.0% 99.0%
3967449 2004.1.1.88 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › cobW 0.66 48.0 4.23e-01 100.0% 52.7%
3428798 2004.1.1.88 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › cobW 0.65 46.0 4.18e-01 100.0% 54.3%
4015969 7514.1.1.6 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › PF26733 0.64 43.0 5.05e-01 87.9% 100.0%
4961355 7550.1.1.1 ↗ a/b three-layered sandwiches › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › TP_methylase 0.63 42.0 4.97e-01 100.0% 97.5%
4084160 2004.1.1.201 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_26 0.63 49.0 4.52e-01 100.0% 64.7%
3973620 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.60 44.0 3.85e-01 100.0% 51.0%
4366696 3949.1.1.1 ↗ alpha arrays › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › IPPT 0.60 45.0 3.96e-01 100.0% 53.2%
5051721 2007.2.1.3 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › FMN_red 0.57 40.0 3.97e-01 71.7% 81.1%
5009886 3110.1.1.0 ↗ a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.57 43.0 4.70e-01 93.6% 94.5%
3908820 2003.1.5.198 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PCMT, Methyltransf_31, PF31200 0.57 51.0 4.06e-01 97.1% 58.3%
3782622 2003.1.1.42 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_2 0.55 45.0 4.29e-01 86.7% 79.5%
4019024 2003.1.1.148 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short, KR 0.55 48.0 3.65e-01 93.6% 54.1%
5040846 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.55 39.0 4.35e-01 85.5% 95.6%
3696918 2003.1.1.42 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_2 0.55 44.0 4.20e-01 85.5% 93.2%
5025847 2007.1.14.5 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › Peripla_BP_2 0.54 33.0 3.64e-01 89.0% 73.2%
3944262 2004.1.1.143 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CBP_BcsQ 0.53 42.0 3.71e-01 100.0% 57.2%
5027308 2004.1.1.10 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATP-synt_ab 0.53 48.0 4.42e-01 100.0% 83.0%
2883891 2003.1.9.2 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › UBA_E1_SCCH 0.52 44.0 3.15e-01 89.0% 92.0%
3396047 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.52 44.0 4.04e-01 100.0% 67.8%
4960054 2004.1.1.200 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_25 0.52 44.0 3.86e-01 90.8% 85.7%
5049276 2003.1.5.12 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_N4_Mtase 0.52 48.0 4.18e-01 100.0% 92.9%
3432410 7516.1.1.35 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Branch 0.51 41.0 3.33e-01 85.5% 78.6%
3491240 2488.1.1.19 ↗ a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › PF27710 0.51 41.0 3.89e-01 85.5% 76.7%
3667840 7516.1.1.35 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Branch 0.51 41.0 3.41e-01 86.1% 68.2%
3188220 2004.1.1.88 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › cobW 0.50 42.0 3.70e-01 100.0% 60.0%
3638928 2006.1.1.4 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › NIF 0.50 41.0 3.64e-01 86.1% 84.5%
4025926 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.50 43.0 4.19e-01 100.0% 83.7%
D2 high residues 112-191
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00709.28 best Adenylsucc_synt 57.5 1.40e-15 100.0% 19.2%
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2v40A02 1.10.300.10 Mainly Alpha › Orthogonal Bundle › Adenylosuccinate Synthetase, subunit A; domain 2 › Adenylosuccinate Synthetase, subunit A, domain 2 0.94 84.0 8.09e-01 100.0% 85.2%
1dj2A02 1.10.300.10 Mainly Alpha › Orthogonal Bundle › Adenylosuccinate Synthetase, subunit A; domain 2 › Adenylosuccinate Synthetase, subunit A, domain 2 0.91 85.0 7.85e-01 100.0% 86.9%
1adeA02 1.10.300.10 Mainly Alpha › Orthogonal Bundle › Adenylosuccinate Synthetase, subunit A; domain 2 › Adenylosuccinate Synthetase, subunit A, domain 2 0.90 84.0 7.70e-01 100.0% 87.0%
6zxqA01 1.10.300.10 Mainly Alpha › Orthogonal Bundle › Adenylosuccinate Synthetase, subunit A; domain 2 › Adenylosuccinate Synthetase, subunit A, domain 2 0.84 77.0 7.31e-01 100.0% 89.2%
1af7A01 1.10.155.10 Mainly Alpha › Orthogonal Bundle › Chemotaxis Receptor Methyltransferase Cher; domain 1 › Chemotaxis receptor methyltransferase CheR, N-terminal domain 0.63 42.0 4.21e-01 81.2% 67.5%
1rx0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.62 53.0 4.27e-01 95.0% 69.0%
1r2jA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 52.0 4.31e-01 95.0% 68.1%
1ivhA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 52.0 4.35e-01 95.0% 83.7%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.60 41.0 4.49e-01 81.2% 86.4%
2bnlC00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.60 52.0 4.39e-01 96.2% 91.8%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.59 45.0 4.07e-01 81.2% 83.3%
4rm7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 52.0 4.37e-01 100.0% 79.1%
2clbA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 51.0 4.14e-01 100.0% 81.1%
1iuqA01 1.10.1200.50 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glycerol-3-phosphate acyltransferase, alpha helical bundle, N-terminal 0.58 42.0 4.35e-01 81.2% 81.6%
2hjmA01 1.20.120.460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like 0.57 48.0 4.76e-01 95.0% 93.0%
6i3mE01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.56 46.0 3.90e-01 91.3% 54.0%
1hbgA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.56 49.0 4.05e-01 98.8% 75.5%
3smvA02 1.10.150.750 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.55 45.0 4.62e-01 98.8% 94.8%
1qusA01 1.10.8.350 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Bacterial muramidase 0.55 42.0 3.75e-01 81.2% 65.5%
2c5uA02 1.10.3550.20 Mainly Alpha › Orthogonal Bundle › eoxyguanosinetriphosphate triphosphohydrolase fold › 0.55 38.0 3.26e-01 80.0% 43.5%
1t6jA03 1.10.274.20 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 0.55 47.0 4.39e-01 100.0% 84.5%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.55 42.0 3.83e-01 82.5% 89.6%
2fi1A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.54 35.0 3.84e-01 100.0% 84.4%
1ldjA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.54 43.0 3.90e-01 90.0% 93.9%
3ns4A00 1.10.357.110 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Vacuolar protein sorting-associated protein 53, C-terminus 0.53 41.0 3.10e-01 85.0% 49.8%
1kxpD04 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.52 39.0 4.05e-01 81.2% 88.3%
1jt6A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 38.0 3.30e-01 80.0% 78.1%
5u56A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 45.0 4.05e-01 95.0% 76.8%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 41.0 4.28e-01 90.0% 94.5%
3bosA02 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.51 31.0 3.26e-01 78.8% 68.7%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.51 38.0 3.53e-01 82.5% 88.8%
2zueA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.50 43.0 3.82e-01 96.2% 94.1%
7r97A01 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.50 42.0 3.49e-01 95.0% 91.2%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4477211 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.95 91.0 5.52e-01 100.0% 19.8%
4036208 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.93 88.0 5.33e-01 100.0% 19.5%
1883519 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.93 88.0 5.34e-01 100.0% 19.1%
4259208 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.93 87.0 5.34e-01 100.0% 21.3%
4639006 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.90 84.0 5.68e-01 100.0% 33.6%
4180893 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.89 84.0 5.08e-01 100.0% 19.3%
4472870 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.89 84.0 5.05e-01 100.0% 22.9%
4644713 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.88 82.0 5.06e-01 100.0% 20.0%
4203696 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.88 82.0 4.93e-01 100.0% 21.2%
5024558 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.87 81.0 4.95e-01 100.0% 20.2%
4158935 2004.1.1.53 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Adenylsucc_synt 0.87 80.0 4.96e-01 100.0% 21.5%
4994061 601.7.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.67 52.0 4.31e-01 83.7% 66.4%
5029782 601.7.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.66 52.0 4.98e-01 82.5% 85.6%
5078378 601.7.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.63 48.0 4.03e-01 82.5% 64.1%
4979030 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.60 52.0 4.35e-01 98.8% 69.7%
3340051 509.1.1.1 ↗ alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › PAH 0.59 43.0 4.37e-01 98.8% 81.2%
5064674 601.7.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.58 44.0 3.89e-01 83.7% 70.2%
3728304 604.12.1.24 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF6604 0.56 39.0 3.61e-01 100.0% 57.0%
3973396 101.1.17.0 ↗ alpha arrays › HTH › HTH › FF domain 0.56 48.0 4.59e-01 97.5% 81.1%
3570364 509.1.1.1 ↗ alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › PAH 0.55 42.0 4.09e-01 96.2% 74.4%
4029270 6058.1.1.1 ↗ alpha arrays › C-terminal alpha domain in Alpha-Glycerophosphate Oxidase › C-terminal alpha domain in Alpha-Glycerophosphate Oxidase › C-terminal alpha domain in Alpha-Glycerophosphate Oxidase › DAO_C 0.55 41.0 3.36e-01 91.3% 43.4%
1206502 604.5.1.2 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.55 42.0 3.83e-01 82.5% 89.6%
4071221 191.1.1.3 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_5 0.53 39.0 3.52e-01 81.2% 91.5%
3227575 3009.1.1.0 ↗ alpha arrays › Insertion subdomain in DsbA-like › Insertion subdomain in DsbA-like › Insertion subdomain in DsbA-like 0.53 45.0 3.40e-01 100.0% 37.6%
3387070 138.1.1.20 ↗ alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › PF30817 0.52 39.0 3.44e-01 81.2% 73.6%
3405478 633.23.1.22 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.52 46.0 3.90e-01 100.0% 77.8%
None — 0.52 44.0 3.03e-01 100.0% 66.3%
4034544 5067.1.1.6 ↗ alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › YibE_F 0.51 43.0 3.22e-01 100.0% 67.2%
3954159 633.6.1.1 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.51 43.0 3.61e-01 98.8% 80.0%
D3 medium residues 267-286_306-374_408-451
PDB