←Back to structures
alkaline_exonuclease
Euk-VirApocheima_cinerarium_nucleopolyhedrovirus
alkaline_exonuclease__YP_006607785__Apocheima_cinerarium_nucleopolyhedrovirus__307461
Identity
- Accession:
- YP_006607785 ↗
- Protein ID:
- alkaline_exonuclease
- Kingdom:
- euk
Quality
82.8
mean pLDDT
Taxonomy
Naldaviricetes›
Lefavirales›
Baculoviridae›
Alphabaculovirus›
Apocheima_cinerarium_nucleopolyhedrovirus
TaxID: 307461
Cluster
View cluster (45 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 251-323
Domain cluster:
rep: alkaline_exonuclease__YP_010086987__Cryptophlebia_peltastica_nucleopolyhedrovirus__2304025__D258-315
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5cqgA04 | 3.30.70.2630 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.50 | 37.0 | 3.37e-01 | 82.2% | 93.4% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3742070 | 381.1.1.1 ↗ | few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR | 0.82 | 71.0 | 6.62e-01 | 93.2% | 93.3% |
| 166845 | 381.1.1.1 ↗ | few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR | 0.77 | 70.0 | 6.19e-01 | 98.6% | 74.8% |
| 4846647 | 381.1.1.1 ↗ | few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR | 0.77 | 70.0 | 6.17e-01 | 100.0% | 75.2% |
| 3167513 | 381.1.1.3 ↗ | few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › zf-C3HC | 0.76 | 61.0 | 5.43e-01 | 87.7% | 89.5% |
| 3931141 | 381.1.1.0 ↗ | few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat | 0.76 | 55.0 | 6.07e-01 | 87.7% | 94.8% |
| 3931217 | 502.1.1.0 ↗ | a+b two layers › Anti-LPS factor/recA domain › Anti-LPS factor/recA domain › Anti-LPS factor/recA domain | 0.73 | 46.0 | 4.82e-01 | 74.0% | 70.8% |
| 3535885 | 386.1.1.226 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › Znf-C2H2_ZNF142 | 0.69 | 35.0 | 4.62e-01 | 84.9% | 100.0% |
| 3621229 | 386.1.1.4 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED | 0.69 | 42.0 | 4.27e-01 | 79.5% | 62.9% |
| 3888040 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.65 | 46.0 | 4.68e-01 | 74.0% | 97.1% |
| 4932374 | 2485.1.1.1 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin | 0.59 | 47.0 | 3.96e-01 | 90.4% | 66.4% |
| 3464575 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.59 | 50.0 | 4.62e-01 | 100.0% | 81.0% |
| 3621574 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.58 | 40.0 | 4.49e-01 | 95.9% | 96.4% |
D2
high
residues 337-400
Domain cluster:
rep: alkaline_exonuclease__YP_009117034__Pseudoplusia_includens_SNPV_IE__1592335__D351-412
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3siqA00 | 1.10.1170.10 | Mainly Alpha › Orthogonal Bundle › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A | 0.79 | 71.0 | 6.02e-01 | 100.0% | 88.3% |
| 2poiA00 | 1.10.1170.10 | Mainly Alpha › Orthogonal Bundle › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A | 0.77 | 68.0 | 6.35e-01 | 98.4% | 98.7% |
| 1i3oF00 | 1.10.1170.10 | Mainly Alpha › Orthogonal Bundle › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A | 0.75 | 68.0 | 5.95e-01 | 100.0% | 72.0% |
| 1rr7A01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.66 | 35.0 | 4.12e-01 | 87.5% | 73.9% |
ECOD (14)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3874336 | 381.1.1.1 ↗ | few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR | 0.83 | 76.0 | 6.89e-01 | 100.0% | 89.4% |
| 166845 | 381.1.1.1 ↗ | few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR | 0.81 | 73.0 | 6.20e-01 | 100.0% | 74.8% |
| 426822 | 381.1.1.1 ↗ | few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR | 0.80 | 72.0 | 5.97e-01 | 98.4% | 83.3% |
| 3171946 | 381.1.1.0 ↗ | few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat | 0.68 | 58.0 | 5.07e-01 | 95.3% | 80.8% |
| 3260511 | 386.1.1.71 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › SURF2 | 0.67 | 47.0 | 5.02e-01 | 75.0% | 96.4% |
| 3260512 | 386.1.1.71 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › SURF2 | 0.66 | 46.0 | 4.87e-01 | 73.4% | 96.4% |
| 3481222 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.61 | 35.0 | 3.16e-01 | 76.6% | 40.0% |
| 3822828 | 376.1.6.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR | 0.59 | 48.0 | 4.78e-01 | 90.6% | 93.8% |
| 3397452 | 386.1.1.4 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED | 0.58 | 39.0 | 4.01e-01 | 70.3% | 80.0% |
| 3328364 | 304.31.1.1 ↗ | a+b two layers › Alpha-beta plaits › HMG-CoA reductase › NAD-binding domain of HMG-CoA reductase › HMG-CoA_red | 0.53 | 37.0 | 2.86e-01 | 71.9% | 72.3% |
| 3190295 | 376.1.6.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain | 0.53 | 34.0 | 3.65e-01 | 90.6% | 78.2% |
| 3636203 | 376.1.4.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR | 0.53 | 37.0 | 3.96e-01 | 90.6% | 88.7% |
| 3956275 | 101.1.11.0 ↗ | alpha arrays › HTH › HTH › Ribbon-helix-helix | 0.52 | 29.0 | 2.90e-01 | 85.9% | 45.7% |
| 3262965 | 376.1.4.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog | 0.50 | 38.0 | 3.85e-01 | 96.9% | 84.4% |
D3
medium
residues 1-144
Domain cluster:
rep: alkaline_exonuclease__YP_009316046__Anticarsia_gemmatalis_multiple_nucleopolyhedrovirus__268591__D1-83_250-276
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01771.24 best | Viral_alk_exo | 28.0 | 1.30e-06 | 92.4% | 24.5% |
D4
medium
residues 145-250
Domain cluster:
representative
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ic1D00 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.74 | 43.0 | 3.43e-01 | 95.3% | 30.1% |
| 8d3mI01 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.65 | 41.0 | 3.22e-01 | 95.3% | 32.4% |
| 4zxhA01 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.64 | 35.0 | 2.99e-01 | 84.0% | 32.2% |
| 5u89A02 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.62 | 33.0 | 2.83e-01 | 83.0% | 31.3% |
| 4hvmB01 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.61 | 34.0 | 2.86e-01 | 83.0% | 30.3% |
| 3h4rA00 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.61 | 45.0 | 3.53e-01 | 100.0% | 37.4% |
| 4jn3A01 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.60 | 34.0 | 2.70e-01 | 83.0% | 26.9% |
| 5zyuA01 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.59 | 43.0 | 3.41e-01 | 95.3% | 39.8% |
| 1tm0A01 | 3.10.310.10 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 | 0.58 | 44.0 | 3.84e-01 | 80.2% | 66.5% |
| 5t3eB01 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.58 | 33.0 | 2.80e-01 | 83.0% | 32.4% |
| 3d2fA04 | 3.90.640.10 | Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 | 0.56 | 31.0 | 3.39e-01 | 71.7% | 66.7% |
| 1s7jA02 | 3.10.310.10 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 | 0.54 | 41.0 | 3.84e-01 | 81.1% | 68.9% |
| 4dunA01 | 3.10.310.10 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 | 0.50 | 37.0 | 3.59e-01 | 83.0% | 67.7% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4942551 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.76 | 48.0 | 3.68e-01 | 92.5% | 30.5% |
| 222168 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.74 | 43.0 | 3.43e-01 | 95.3% | 30.1% |
| 3274159 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.73 | 40.0 | 3.91e-01 | 83.0% | 48.7% |
| 4955488 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.72 | 44.0 | 4.34e-01 | 91.5% | 58.2% |
| 5058512 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.70 | 46.0 | 3.29e-01 | 95.3% | 24.9% |
| 5075190 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.69 | 40.0 | 3.49e-01 | 93.4% | 38.1% |
| 3693544 | 2008.1.1.147 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF29557 | 0.69 | 44.0 | 3.07e-01 | 100.0% | 20.3% |
| 3725765 | 2008.1.1.147 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF29557 | 0.69 | 45.0 | 3.61e-01 | 100.0% | 34.6% |
| 3414564 | 2008.1.1.29 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Dna2 | 0.68 | 42.0 | 3.02e-01 | 95.3% | 23.2% |
| 3617935 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.68 | 45.0 | 3.84e-01 | 100.0% | 41.4% |
| 5082574 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.68 | 39.0 | 3.41e-01 | 92.5% | 38.1% |
| 5005960 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.67 | 43.0 | 3.50e-01 | 95.3% | 37.0% |
| 5077420 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.66 | 43.0 | 3.32e-01 | 95.3% | 31.1% |
| 3950933 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.66 | 43.0 | 3.17e-01 | 85.8% | 26.0% |
| 5072012 | 2008.1.1.3 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Hjc | 0.66 | 31.0 | 3.34e-01 | 81.1% | 50.0% |
| 3226148 | 2008.1.1.29 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Dna2 | 0.65 | 38.0 | 2.76e-01 | 84.9% | 21.8% |
| 4969306 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.65 | 41.0 | 3.00e-01 | 92.5% | 25.3% |
| 3976411 | 2008.1.1.58 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF3799 | 0.64 | 48.0 | 3.61e-01 | 100.0% | 32.7% |
| 3574786 | 2.1.1.44 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Dna2 | 0.63 | 36.0 | 2.62e-01 | 84.9% | 20.0% |
| 5077680 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.62 | 38.0 | 3.21e-01 | 95.3% | 37.1% |
| 5012280 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.61 | 47.0 | 3.77e-01 | 95.3% | 42.0% |
| 3243571 | 286.1.1.2 ↗ | a+b complex topology › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › PhzC-PhzF | 0.61 | 36.0 | 2.94e-01 | 84.9% | 31.6% |
| 3254723 | 859.1.1.3 ↗ | a+b two layers › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 › ATG101 | 0.58 | 41.0 | 3.48e-01 | 71.7% | 53.9% |
| 5021943 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.58 | 35.0 | 2.71e-01 | 87.7% | 25.8% |
| 4955137 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.57 | 37.0 | 3.15e-01 | 100.0% | 38.9% |
| 4953680 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.57 | 35.0 | 2.67e-01 | 84.9% | 24.7% |
| 4555637 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.54 | 39.0 | 3.30e-01 | 99.1% | 43.9% |
| 4048956 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.54 | 35.0 | 3.02e-01 | 99.1% | 39.9% |
| 5056632 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.53 | 39.0 | 3.00e-01 | 83.0% | 33.8% |
| 4048866 | 286.1.1.2 ↗ | a+b complex topology › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › PhzC-PhzF | 0.51 | 38.0 | 3.48e-01 | 82.1% | 66.0% |
| 3587443 | 7523.1.1.22 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › ABC2_membrane_3 | 0.50 | 29.0 | 2.91e-01 | 82.1% | 55.5% |