←Back to structures

alkaline_exonuclease

Euk-Vir

Murine_roseolovirus

alkaline_exonuclease__YP_009344916__Murine_roseolovirus__1940555

Identity

Accession:: YP_009344916 ↗
Protein ID:: alkaline_exonuclease
Kingdom:: euk

Quality

84.6 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Roseolovirus› Murine_roseolovirus

TaxID: 1940555

Cluster

View cluster (76 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-132

PDB

Domain cluster: rep: GP98__YP_007417864__Caviid_betaherpesvirus_2__33706__D55-187

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01771.24 best	Viral_alk_exo	33.8	2.30e-08	95.4%	23.6%

CATH (18)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2w45A01	1.20.120.860	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Herpesvirus alkaline exonuclease, N-terminal domain	0.82	68.0	7.16e-01	100.0%	97.4%
3fhdA01	1.20.120.860	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Herpesvirus alkaline exonuclease, N-terminal domain	0.80	68.0	6.73e-01	100.0%	86.0%
4fp4A00	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.67	48.0	3.88e-01	73.8%	60.5%
3lomA00	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.64	47.0	3.62e-01	76.2%	57.6%
2qq8A02	1.10.8.270	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › putative rabgap domain of human tbc1 domain family member 14 like domains	0.62	35.0	3.97e-01	79.2%	74.0%
3b34A03	1.10.390.10	Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2	0.59	45.0	4.23e-01	81.5%	97.6%
1wgwA00	1.20.120.140	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain	0.58	32.0	3.61e-01	71.5%	68.7%
1abvA00	1.10.520.20	Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase	0.58	28.0	3.05e-01	100.0%	53.3%
2np3A00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.57	33.0	3.29e-01	73.1%	52.8%
3doeB00	1.20.1520.10	Mainly Alpha › Up-down Bundle › Adp-ribosylation factor-like protein 2-binding protein fold › ADP-ribosylation factor-like 2-binding protein, domain	0.56	38.0	4.11e-01	100.0%	80.7%
1ls1A01	1.20.120.140	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain	0.56	30.0	3.55e-01	70.0%	75.3%
1cy5A00	1.10.533.10	Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas	0.55	35.0	3.94e-01	76.9%	88.0%
2dbdA00	1.10.533.10	Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas	0.55	38.0	4.13e-01	78.5%	86.9%
3c1yA02	1.20.1260.110	Mainly Alpha › Up-down Bundle › Ferritin › DNA integrity scanning linker region	0.53	39.0	3.82e-01	77.7%	95.3%
1tqnA00	1.10.630.10	Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450	0.53	47.0	3.26e-01	100.0%	70.7%
5dkoA02	1.10.3900.10	Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like	0.52	45.0	4.18e-01	96.9%	95.8%
2oezA02	1.10.3900.10	Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like	0.51	43.0	4.03e-01	93.8%	95.7%
3h37A03	1.20.58.1960	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.50	35.0	3.57e-01	71.5%	78.9%

ECOD (17)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5069390	3236.1.1.1 ↗	alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger	0.60	42.0	3.01e-01	71.5%	83.6%
3485337	110.1.1.2 ↗	alpha arrays › DEATH domain › DEATH domain › DEATH domain › CARD	0.59	37.0	4.09e-01	76.9%	80.0%
4944407	131.1.1.14 ↗	alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › Cas3_HD	0.55	38.0	2.95e-01	70.0%	73.4%
5059164	4070.1.1.0 ↗	alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like	0.54	38.0	3.12e-01	71.5%	90.7%
3341287	3754.1.1.1 ↗	alpha bundles › Bacterial cell wall synthesis membrane enzyme MraY-related › Bacterial cell wall synthesis membrane enzyme MraY-related › Bacterial cell wall synthesis membrane enzyme MraY-related › Glycos_transf_4	0.54	45.0	3.37e-01	93.8%	54.4%
4161966	149.1.1.1 ↗	alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450	0.54	48.0	3.51e-01	100.0%	86.5%
3948183	5059.1.1.1 ↗	alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA	0.53	43.0	3.37e-01	88.5%	78.3%
3988991	181.1.1.1 ↗	alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N	0.53	29.0	3.39e-01	71.5%	74.4%
4972788	601.2.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes	0.53	39.0	4.18e-01	91.5%	89.1%
5053682	5059.1.1.1 ↗	alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA	0.53	41.0	3.47e-01	82.3%	99.1%
3193627	3447.1.1.3 ↗	alpha bundles › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › DUF1295	0.53	46.0	3.54e-01	97.7%	86.5%
3286379	633.6.1.0 ↗	alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like	0.52	36.0	3.70e-01	77.7%	72.8%
4424177	7014.1.1.2 ↗	alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE	0.52	35.0	3.71e-01	93.8%	75.0%
3701447	524.1.1.1 ↗	alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p › RabGAP-TBC	0.52	38.0	3.82e-01	83.8%	74.8%
3215369	188.1.1.1 ↗	alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep	0.52	41.0	3.28e-01	84.6%	74.8%
3587597	162.1.1.0 ↗	alpha bundles › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD	0.52	37.0	3.81e-01	73.8%	93.6%
5019429	5059.1.1.1 ↗	alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA	0.50	40.0	3.06e-01	87.7%	69.3%

D2 medium residues 156-194_232-358_402-437

PDB

Domain cluster: rep: deoxyribonuclease__YP_443858__Papiine_alphaherpesvirus_2__340907__D355-603

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01771.24 best	Viral_alk_exo	78.3	7.40e-22	64.8%	23.6%

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4k3cA01	3.10.20.310	Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac	0.55	23.0	3.44e-01	93.6%	92.7%

ECOD (6)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
182718	2008.1.1.2 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Viral_alk_exo	0.85	79.0	5.86e-01	96.0%	56.2%
4944561	512.1.1.0 ↗	a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523)	0.56	20.0	2.75e-01	72.8%	60.0%
4946616	512.1.1.2 ↗	a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_2nd	0.55	19.0	2.77e-01	73.8%	64.4%
4466937	11.1.1.248 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › bMG6	0.54	27.0	3.24e-01	74.8%	70.8%
3846627	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.51	23.0	3.12e-01	80.2%	81.0%
5073695	512.1.1.1 ↗	a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_1st	0.51	19.0	2.56e-01	70.8%	61.0%

D3 medium residues 195-231_359-401

PDB

Domain cluster: representative

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01771.24 best	Viral_alk_exo	34.7	1.20e-08	53.8%	8.7%
PF01771.24	Viral_alk_exo	23.6	2.80e-05	46.2%	8.0%

CATH (21)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1yj7D02	3.30.300.30	Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain	0.61	45.0	4.45e-01	100.0%	72.4%
2zztA00	3.30.70.1350	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cation efflux protein, cytoplasmic domain	0.60	44.0	4.41e-01	100.0%	76.8%
2z3vA00	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.58	43.0	3.60e-01	78.8%	58.4%
4wnyA00	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.58	44.0	3.72e-01	81.2%	62.1%
2yogA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.56	46.0	3.58e-01	95.0%	57.9%
4d86A01	3.40.220.10	Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1	0.56	42.0	3.30e-01	82.5%	55.9%
3f8tA01	1.10.260.200	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) ›	0.56	49.0	4.88e-01	100.0%	98.8%
8dqaA01	3.30.429.10	Alpha Beta › 2-Layer Sandwich › Macrophage Migration Inhibitory Factor › Macrophage Migration Inhibitory Factor	0.55	42.0	4.02e-01	83.7%	100.0%
4ge6A00	3.90.190.10	Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily	0.55	43.0	2.91e-01	83.7%	24.1%
1ib8A01	3.30.300.70	Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › RimP-like superfamily, N-terminal	0.55	42.0	4.25e-01	100.0%	81.9%
5nfmA00	3.30.300.90	Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › BolA-like	0.53	39.0	4.03e-01	100.0%	84.0%
1d2gA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.53	38.0	2.91e-01	75.0%	84.6%
2plrA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.53	44.0	3.31e-01	93.8%	52.4%
2i7tA01	3.60.15.10	Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like	0.53	38.0	2.72e-01	87.5%	24.1%
2jieA00	3.20.20.80	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases	0.52	44.0	2.78e-01	95.0%	93.5%
2e7gA01	3.30.300.20	Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain	0.52	44.0	4.07e-01	100.0%	72.6%
6torA01	3.90.1150.10	Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1	0.51	37.0	3.06e-01	75.0%	87.5%
6aeoB01	3.30.1330.60	Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › OmpA-like domain	0.51	45.0	3.80e-01	100.0%	63.0%
1egaA02	3.30.300.20	Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain	0.51	45.0	4.10e-01	100.0%	75.5%
4ol9A01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.50	43.0	3.48e-01	100.0%	94.7%
3mogA03	3.30.750.190	Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA ›	0.50	43.0	4.08e-01	93.8%	87.2%

ECOD (42)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3586805	327.7.1.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like	0.62	47.0	4.61e-01	100.0%	74.1%
3546432	327.7.1.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like	0.62	46.0	4.47e-01	100.0%	70.0%
3412298	7523.1.1.0 ↗	a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II	0.61	53.0	4.41e-01	100.0%	79.3%
3743715	327.7.1.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like	0.61	45.0	4.53e-01	88.7%	77.5%
3595358	327.7.1.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like	0.60	45.0	4.36e-01	100.0%	70.0%
4382439	327.7.1.1 ↗	a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer	0.60	45.0	4.37e-01	100.0%	71.1%
4134873	301.7.1.3 ↗	a+b three layers › Bacillus chorismate mutase-like › YjgF-like › YjgF-like › Amido_AtzD_TrzD	0.59	47.0	4.22e-01	88.7%	63.5%
4931728	2008.1.1.212 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF27326	0.57	46.0	3.65e-01	100.0%	41.8%
3603331	327.4.1.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › YhbC-like, N-terminal domain › YhbC-like, N-terminal domain	0.57	50.0	4.54e-01	97.5%	72.4%
5037208	2004.1.1.79 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin	0.57	47.0	3.60e-01	97.5%	57.7%
3594878	3003.1.1.0 ↗	a+b complex topology › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54)	0.57	46.0	4.05e-01	91.3%	96.8%
4277444	2484.1.1.97 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas9_RuvC	0.56	44.0	3.04e-01	85.0%	55.1%
5016234	327.7.1.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like	0.56	42.0	4.19e-01	100.0%	75.3%
5029780	316.1.1.2 ↗	a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2	0.56	45.0	3.73e-01	87.5%	54.3%
3215980	3003.1.1.1 ↗	a+b complex topology › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › MCM_N	0.56	46.0	4.21e-01	92.5%	81.8%
3688023	206.1.1.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase	0.56	44.0	2.56e-01	86.3%	9.9%
5029779	316.1.1.0 ↗	a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase	0.55	41.0	3.59e-01	78.8%	64.2%
5055967	7516.1.1.189 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › MGS_GT	0.55	46.0	3.03e-01	97.5%	29.5%
4929217	3003.1.1.1 ↗	a+b complex topology › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › MCM_N	0.55	46.0	4.36e-01	95.0%	95.0%
4228205	324.1.1.1 ↗	a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC	0.54	47.0	3.93e-01	98.8%	55.0%
4952303	2004.1.1.79 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin	0.54	44.0	3.52e-01	95.0%	59.5%
4680580	2004.1.1.415 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA, RuvB_N	0.54	38.0	2.71e-01	72.5%	42.4%
5012774	324.1.1.0 ↗	a+b two layers › OsmC-like › OsmC-like › OsmC-like	0.54	45.0	4.25e-01	100.0%	76.8%
5083710	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.54	37.0	2.57e-01	71.2%	34.0%
3426929	7512.1.1.0 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase	0.54	41.0	2.91e-01	82.5%	32.7%
3290764	327.7.1.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like	0.54	44.0	4.37e-01	100.0%	84.7%
5075804	2484.1.1.337 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RRXRR	0.54	43.0	3.32e-01	87.5%	39.5%
3715351	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.53	40.0	2.86e-01	78.8%	30.4%
4944695	327.5.1.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins	0.53	46.0	4.17e-01	100.0%	70.0%
3785896	327.7.1.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like	0.53	40.0	4.08e-01	100.0%	81.2%
4275412	327.10.1.2 ↗	a+b two layers › Alpha-lytic protease prodomain-like › Ribosome-binding factor A (RbfA)-related › Ribosome-binding factor A (RbfA)-related › RBFA	0.53	44.0	3.99e-01	100.0%	68.2%
4448090	327.17.1.7 ↗	a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_N, S-AdoMet_synt_M, S-AdoMet_synt_C	0.53	46.0	2.97e-01	100.0%	22.7%
3699798	327.7.1.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like	0.52	39.0	3.83e-01	100.0%	72.2%
3996689	224.1.1.1 ↗	a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Cofilin_ADF	0.52	36.0	3.55e-01	85.0%	67.1%
4088599	327.10.1.2 ↗	a+b two layers › Alpha-lytic protease prodomain-like › Ribosome-binding factor A (RbfA)-related › Ribosome-binding factor A (RbfA)-related › RBFA	0.52	44.0	4.06e-01	100.0%	70.9%
5046722	2003.1.5.66 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11	0.52	42.0	3.00e-01	90.0%	42.7%
3751659	224.1.1.2 ↗	a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin	0.52	45.0	3.87e-01	97.5%	75.4%
3178718	224.1.1.1 ↗	a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Cofilin_ADF	0.52	37.0	3.15e-01	77.5%	85.0%
4962337	327.6.1.2 ↗	a+b two layers › Alpha-lytic protease prodomain-like › Fe-S cluster assembly (FSCA) domain-like › Fe-S cluster assembly (FSCA) domain-like › FeS_assembly_P	0.51	45.0	4.15e-01	100.0%	74.3%
3287861	327.7.1.4 ↗	a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › Asp23	0.51	46.0	4.01e-01	100.0%	76.7%
4576909	327.17.1.3 ↗	a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_M	0.51	44.0	3.82e-01	100.0%	63.8%
3371599	327.11.1.1 ↗	a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) › KH_2	0.50	44.0	4.16e-01	100.0%	80.0%

D4 medium residues 440-482

PDB

Domain cluster: rep: rh134__YP_068225__Macacine_betaherpesvirus_3__47929__D510-548