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alkaline_exonuclease

Euk-Vir

Cryptophlebia_peltastica_nucleopolyhedrovirus

alkaline_exonuclease__YP_010086987__Cryptophlebia_peltastica_nucleopolyhedrovirus__2304025

Identity

Accession:
YP_010086987 ↗
Protein ID:
alkaline_exonuclease
Kingdom:
euk

Quality

87.2 mean pLDDT

Taxonomy

Naldaviricetes› Lefavirales› Baculoviridae› Alphabaculovirus› Cryptophlebia_peltastica_nucleopolyhedrovirus

TaxID: 2304025

Cluster

View cluster (45 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 58-240
PDB
Domain cluster: rep: ALK-EXO__YP_009250080__Urbanus_proteus_nucleopolyhedrovirus__1675866__D84-261
D2 high residues 258-315
PDB
Domain cluster: representative
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2poiA00 1.10.1170.10 Mainly Alpha › Orthogonal Bundle › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A › Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 0.76 68.0 6.15e-01 100.0% 76.9%
2w9mA04 3.30.210.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 3 › DNA polymerase, thumb domain 0.65 46.0 4.75e-01 75.9% 85.5%
6wm6A01 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.65 44.0 2.90e-01 70.7% 64.9%
2d6fC03 1.10.150.380 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › GatB domain, N-terminal subdomain 0.61 47.0 4.89e-01 100.0% 96.2%
5oklA01 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.60 49.0 4.08e-01 89.7% 70.3%
5cbgA00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.60 41.0 3.50e-01 72.4% 54.9%
5hr9A02 3.30.210.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 3 › DNA polymerase, thumb domain 0.59 42.0 4.04e-01 75.9% 73.9%
6ukcA00 1.10.530.10 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.59 51.0 3.94e-01 100.0% 81.2%
2aklA01 2.20.25.10 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.57 36.0 4.07e-01 86.2% 88.4%
4y7dA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 49.0 3.14e-01 100.0% 42.9%
2y1eA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.55 48.0 4.25e-01 100.0% 93.1%
2pbfA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 46.0 3.21e-01 100.0% 47.7%
3p2mA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.55 45.0 2.90e-01 93.1% 39.5%
1tkeA03 3.30.54.20 Alpha Beta › 2-Layer Sandwich › Replication Terminator Protein; Chain A, domain 2 › 0.54 38.0 3.88e-01 77.6% 86.2%
1go3E01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.54 40.0 3.53e-01 84.5% 80.9%
4xcgA02 3.30.260.10 Alpha Beta › 2-Layer Sandwich › GROEL; domain 2 › TCP-1-like chaperonin intermediate domain 0.54 45.0 3.74e-01 98.3% 65.5%
1zymA01 3.50.30.10 Alpha Beta › 3-Layer(bba) Sandwich › Glucose Oxidase; domain 1 › Phosphohistidine domain 0.54 37.0 3.11e-01 77.6% 83.5%
3clpC00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.53 43.0 3.40e-01 93.1% 86.5%
3qitB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 42.0 2.73e-01 89.7% 39.9%
3iieB03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.52 44.0 3.97e-01 100.0% 94.1%
4idhA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 35.0 2.47e-01 70.7% 41.8%
5cqgA04 3.30.70.2630 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 40.0 3.33e-01 87.9% 82.1%
3n0uA02 1.10.340.30 Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Hypothetical protein; domain 2 0.51 41.0 3.42e-01 94.8% 48.6%
4cc9A00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.51 40.0 2.59e-01 89.7% 33.2%
2el8A01 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.51 40.0 3.58e-01 94.8% 59.3%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3931141 381.1.1.0 ↗ few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat 0.83 64.0 6.45e-01 98.3% 81.0%
4094681 381.1.1.1 ↗ few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.79 72.0 5.01e-01 100.0% 33.5%
3940508 386.1.1.4 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED 0.77 49.0 5.00e-01 72.4% 67.3%
3865601 381.1.1.1 ↗ few secondary structure elements › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › Inhibitor of apoptosis (IAP) repeat › BIR 0.76 69.0 6.05e-01 100.0% 70.6%
3535885 386.1.1.226 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › Znf-C2H2_ZNF142 0.72 37.0 4.56e-01 96.6% 82.9%
3621229 386.1.1.4 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-BED 0.66 42.0 4.04e-01 81.0% 54.3%
5061951 66.1.1.4 ↗ beta sandwiches › ISP domain › ISP domain › ISP domain › FtrD-like 0.65 50.0 3.93e-01 82.8% 64.4%
3759995 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.65 48.0 3.12e-01 81.0% 22.7%
3284160 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.63 42.0 4.72e-01 82.8% 100.0%
4989659 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.63 44.0 3.42e-01 74.1% 84.6%
3639147 223.1.1.21 ↗ a+b three layers › Profilin-like › sensor domains › sensor domains › HODM_asu-like 0.59 41.0 2.61e-01 72.4% 15.7%
5023627 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.59 43.0 2.92e-01 77.6% 39.5%
4097350 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.59 51.0 4.95e-01 100.0% 92.3%
4226297 7014.1.1.1 ↗ alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA 0.59 41.0 3.25e-01 74.1% 60.0%
5060162 66.1.1.4 ↗ beta sandwiches › ISP domain › ISP domain › ISP domain › FtrD-like 0.59 48.0 3.83e-01 93.1% 75.8%
5011867 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.59 41.0 2.98e-01 74.1% 89.9%
5050229 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.58 37.0 3.54e-01 82.8% 54.3%
3484622 386.1.1.1 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-C2H2 0.57 39.0 3.58e-01 70.7% 51.2%
4031797 375.1.1.47 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › BshC 0.57 44.0 4.51e-01 89.7% 87.3%
4975908 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.57 40.0 2.75e-01 74.1% 85.9%
5055179 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.57 41.0 2.86e-01 77.6% 44.8%
4928885 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.57 38.0 4.12e-01 84.5% 88.9%
3523495 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.57 35.0 3.25e-01 96.6% 43.8%
4996238 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.56 39.0 2.88e-01 74.1% 43.5%
4943798 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.55 40.0 2.80e-01 81.0% 41.8%
5025801 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.55 40.0 2.86e-01 79.3% 42.7%
3371150 143.1.1.0 ↗ alpha arrays › PABP domain-like › PABC(PABP) domain › PABC(PABP) domain 0.54 43.0 4.36e-01 96.6% 96.4%
5000042 2484.1.1.302 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.54 39.0 2.76e-01 79.3% 39.0%
4144086 166.1.1.1 ↗ alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.52 44.0 3.79e-01 100.0% 80.0%
3272054 2498.1.1.23 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M49 0.52 42.0 2.55e-01 100.0% 49.8%
3736950 223.1.1.21 ↗ a+b three layers › Profilin-like › sensor domains › sensor domains › HODM_asu-like 0.51 44.0 2.79e-01 98.3% 40.0%
3990082 7579.1.1.0 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.51 42.0 2.89e-01 98.3% 97.0%
4120005 7579.1.1.44 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_6 0.50 40.0 2.72e-01 91.4% 62.1%
3416069 331.1.1.0 ↗ a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like 0.50 35.0 3.36e-01 74.1% 72.9%
D3 high residues 334-394
PDB
Domain cluster: rep: alkaline_exonuclease__YP_009117034__Pseudoplusia_includens_SNPV_IE__1592335__D351-412
D4 medium residues 1-57_247-257
PDB
Domain cluster: rep: alkaline_exonuclease__YP_009117034__Pseudoplusia_includens_SNPV_IE__1592335__D14-68
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01771.24 best Viral_alk_exo 26.6 3.50e-06 91.2% 8.0%