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alkaline_exonuclease

Euk-Vir

Vombatid_gammaherpesvirus_1

alkaline_exonuclease__YP_010087409__Vombatid_gammaherpesvirus_1__2052651

Identity

Accession:
YP_010087409 ↗
Protein ID:
alkaline_exonuclease
Kingdom:
euk

Quality

82.1 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Manticavirus› Vombatid_gammaherpesvirus_1

TaxID: 2052651

Cluster

View cluster (70 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 23-71_104-179
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01677.23 best Herpes_UL7 58.2 1.20e-15 64.8% 38.1%
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2lsgA00 1.20.58.1280 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DNA repair protein Rev1, C-terminal domain 0.66 49.0 5.50e-01 91.2% 100.0%
1f59A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.65 55.0 3.79e-01 92.0% 56.6%
8f7aA01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.65 55.0 3.44e-01 92.0% 41.1%
7unkA01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.63 54.0 3.44e-01 91.2% 28.8%
5cwkA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 51.0 4.63e-01 85.6% 72.0%
6xu2A01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.63 54.0 3.44e-01 92.8% 31.6%
2l6jA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 45.0 4.73e-01 86.4% 82.9%
5x8tT00 3.90.470.10 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Ribosomal protein L22/L17 0.62 32.0 3.11e-01 92.8% 43.8%
4ffbC00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.60 53.0 4.32e-01 95.2% 54.1%
6tblB01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.60 47.0 5.02e-01 82.4% 97.3%
2uvaG01 1.20.1050.120 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 45.0 4.37e-01 78.4% 82.4%
5dlqB01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.60 47.0 3.26e-01 84.8% 34.9%
4c0qB00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.58 51.0 3.12e-01 94.4% 18.4%
2lseA00 1.20.120.1360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.58 39.0 4.24e-01 95.2% 83.2%
3l9tA02 1.25.40.290 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › ARM repeat domains 0.58 49.0 5.08e-01 95.2% 96.6%
3a11B01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.58 43.0 4.38e-01 78.4% 96.8%
3zheA02 1.25.40.760 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 49.0 4.20e-01 94.4% 84.5%
6g28A00 1.10.4080.10 Mainly Alpha › Orthogonal Bundle › ADP-ribosylglycohydrolase fold › ADP-ribosylation/Crystallin J1 0.57 49.0 3.62e-01 96.8% 64.9%
2psmA00 1.20.1250.70 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-15/Interleukin-21 0.57 36.0 3.74e-01 91.2% 67.5%
4gpkF02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 50.0 4.07e-01 98.4% 64.6%
4bmoA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.56 41.0 3.17e-01 76.8% 82.1%
3hl6A02 1.20.58.700 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 37.0 3.87e-01 70.4% 73.0%
2q9rA01 1.20.1590.10 Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like 0.56 40.0 3.48e-01 99.2% 48.2%
1lwbA00 1.20.90.10 Mainly Alpha › Up-down Bundle › Phospholipase A2 › Phospholipase A2 domain 0.52 36.0 3.70e-01 70.4% 94.3%
1t9kA01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.52 42.0 4.07e-01 87.2% 80.0%
6hwjA01 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.52 39.0 3.21e-01 80.0% 97.5%
1t5oA01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.51 42.0 4.12e-01 97.6% 81.6%
1adoA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.51 44.0 3.25e-01 97.6% 87.9%
2hsnA02 1.20.1050.110 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.50 38.0 4.09e-01 98.4% 92.5%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5002309 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.67 44.0 3.86e-01 92.0% 46.9%
3410618 109.4.1.1446 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RRP12_HEAT, HEAT_RRP12_N 0.66 57.0 3.28e-01 92.8% 19.1%
3683656 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 43.0 4.85e-01 82.4% 86.3%
3784853 109.4.1.182 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec7-like_HUS,DCB 0.63 54.0 3.97e-01 93.6% 68.5%
3916985 109.4.1.632 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MMS22L_C 0.63 56.0 3.78e-01 96.0% 33.9%
3611311 109.4.1.765 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vac14_Fab1_bd 0.63 57.0 5.17e-01 98.4% 87.9%
3592404 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 54.0 3.86e-01 92.8% 56.3%
3565234 109.4.1.651 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm_2 0.63 53.0 4.14e-01 93.6% 43.5%
4261210 109.4.1.296 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › AimR 0.62 56.0 4.38e-01 97.6% 55.0%
3188629 109.4.1.58 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Not1 0.62 54.0 3.54e-01 93.6% 30.5%
3914850 109.4.1.156 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › UNC45-central 0.62 53.0 3.21e-01 92.0% 31.4%
3768141 109.4.1.910 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_MROH2B_C 0.62 50.0 3.85e-01 87.2% 52.9%
3577062 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 56.0 3.85e-01 100.0% 38.1%
4002299 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 53.0 3.69e-01 95.2% 33.4%
3746108 109.4.1.651 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm_2 0.61 51.0 4.10e-01 88.8% 49.6%
3938613 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 53.0 3.09e-01 95.2% 53.1%
3297454 109.4.1.1146 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_PUB 0.60 52.0 3.78e-01 92.8% 49.4%
3613525 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 51.0 4.04e-01 94.4% 54.1%
3253199 109.4.1.177 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cnd3 0.60 54.0 3.18e-01 98.4% 29.9%
3312407 109.4.1.1146 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_PUB 0.58 51.0 3.89e-01 95.2% 45.1%
3419146 3948.1.1.0 ↗ alpha bundles › V(D)J recombination-activating protein 1 helical bundle domain › V(D)J recombination-activating protein 1 helical bundle domain › V(D)J recombination-activating protein 1 helical bundle domain 0.53 48.0 4.07e-01 100.0% 80.5%
3669720 4967.1.1.16 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › TERT_C 0.52 44.0 3.81e-01 94.4% 81.8%
3938712 189.1.1.2 ↗ alpha bundles › GTPase activation domain, GAP › GTPase activation domain, GAP › GTPase activation domain, GAP › RhoGAP 0.51 40.0 3.37e-01 81.6% 81.0%
135559 186.1.1.5 ↗ alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_3 0.51 34.0 3.66e-01 96.0% 81.6%
5074861 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.50 45.0 3.30e-01 100.0% 67.2%
D2 medium residues 72-103_215-265
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01677.23 best Herpes_UL7 34.7 2.00e-08 48.2% 18.0%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xs6A00 1.10.555.10 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein 0.50 37.0 3.04e-01 79.5% 60.2%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3434976 109.4.1.166 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF3535 0.51 35.0 2.25e-01 72.3% 54.2%