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ankyrin-like_protein_NFkB_inhibitor

Euk-Vir

NY_014_poxvirus

ankyrin-like_protein_NFkB_inhibitor__YP_009408572__NY_014_poxvirus__2025360

Identity

Accession:: YP_009408572 ↗
Protein ID:: ankyrin-like_protein_NFkB_inhibitor
Kingdom:: euk

Quality

87.8 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Centapoxvirus› NY_014_poxvirus

TaxID: 2025360

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 271-345

PDB

Domain cluster: representative

CATH (4)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4o6yB00	1.20.120.1770	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.76	54.0	3.84e-01	73.3%	33.6%
1br0A00	1.20.58.70	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.70	55.0	4.67e-01	84.0%	68.3%
3ck6C02	1.20.58.340	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region	0.63	50.0	4.39e-01	89.3%	63.0%
1gqeA01	1.20.58.410	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor	0.50	43.0	3.85e-01	100.0%	75.2%

ECOD (9)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3270696	604.7.1.1 ↗	alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA	0.69	54.0	4.78e-01	84.0%	80.0%
5078126	1075.1.2.1 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX	0.68	46.0	3.68e-01	70.7%	37.4%
3515030	101.1.2.712 ↗	alpha arrays › HTH › HTH › winged helix domain › FNIP_C	0.67	53.0	3.57e-01	86.7%	22.9%
4595949	1025.1.1.0 ↗	alpha bundles › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin helical domain	0.67	58.0	5.06e-01	94.7%	70.0%
3899930	603.1.1.1 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin	0.65	53.0	3.93e-01	89.3%	43.0%
3914404	1025.1.1.1 ↗	alpha bundles › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin_helical	0.65	57.0	4.82e-01	98.7%	81.5%
3387127	109.4.1.206 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › YfiO	0.64	59.0	4.32e-01	100.0%	43.2%
4017411	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.61	51.0	4.14e-01	94.7%	87.3%
3697794	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.57	51.0	4.53e-01	100.0%	71.8%

D2 medium residues 146-211

PDB

Domain cluster: representative

CATH (6)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2zgdA00	1.25.40.20	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain	0.76	63.0	5.52e-01	90.9%	70.1%
2i2xB01	1.10.1240.10	Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain	0.71	57.0	5.00e-01	89.4%	83.0%
3mkqB00	1.25.40.470	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.64	57.0	4.17e-01	100.0%	37.3%
3jq1B01	1.25.40.390	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.60	49.0	3.34e-01	100.0%	52.1%
1qe0A01	3.30.930.10	Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2	0.57	48.0	3.21e-01	100.0%	63.5%
4i8iA00	3.40.50.1110	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase	0.52	43.0	2.96e-01	95.5%	91.9%

ECOD (8)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3537368	109.3.1.164 ↗	alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_3, Ank_4	0.74	66.0	5.22e-01	100.0%	54.8%
4929949	4995.1.1.1 ↗	alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2	0.74	59.0	5.51e-01	89.4%	95.3%
3647722	109.4.1.1275 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3, PPR_long, TPR_24	0.73	62.0	3.66e-01	100.0%	13.9%
3264552	109.3.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat	0.72	63.0	5.64e-01	100.0%	75.8%
3342481	109.4.1.1262 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_long	0.68	60.0	4.15e-01	100.0%	34.3%
3463977	109.4.1.1374 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, TPR_24	0.66	54.0	3.66e-01	95.5%	25.4%
3379603	109.4.1.1383 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, DYW_deaminase, Eplus_motif, E_motif	0.66	58.0	3.31e-01	100.0%	9.3%
3317056	109.4.1.420 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR	0.64	54.0	4.32e-01	100.0%	59.3%

D3 medium residues 212-263

PDB

Domain cluster: representative

CATH (8)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3c7jA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.66	57.0	4.81e-01	100.0%	67.0%
3onqA01	1.20.5.5100	Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.63	46.0	4.94e-01	78.8%	97.6%
4izzB02	1.10.10.1680	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › HetR, N-terminal DNA-binding domain	0.62	45.0	4.17e-01	78.8%	67.6%
3bemB00	3.40.109.10	Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase	0.55	48.0	3.20e-01	100.0%	67.0%
3f0cA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.53	37.0	3.82e-01	76.9%	100.0%
1fkwA00	3.20.20.140	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases	0.52	41.0	2.59e-01	98.1%	32.1%
2iylD01	1.20.120.140	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain	0.51	40.0	3.78e-01	86.5%	84.6%
1k92A02	3.90.1260.10	Alpha Beta › Alpha-Beta Complex › Argininosuccinate synthetase, chain A, domain 2 › Argininosuccinate synthetase, chain A, domain 2	0.51	44.0	2.95e-01	100.0%	93.5%

ECOD (5)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4028110	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.76	52.0	3.51e-01	73.1%	42.6%
4282164	3455.1.1.4 ↗	alpha arrays › WY-domain in RXLR effectors › WY-domain in RXLR effectors › WY-domain in RXLR effectors › ATR1_WY-dom	0.65	49.0	4.28e-01	88.5%	84.4%
5045841	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.63	47.0	3.76e-01	82.7%	48.2%
3688828	604.10.1.0 ↗	alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac	0.57	40.0	3.70e-01	75.0%	98.6%
3685464	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.53	37.0	3.14e-01	76.9%	73.0%