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ankyrin-repeat_protein
Euk-VirPithovirus_sibericum
ankyrin-repeat_protein__YP_009000956__Pithovirus_sibericum__1450746
Identity
- Accession:
- YP_009000956 ↗
- Protein ID:
- ankyrin-repeat_protein
- Kingdom:
- euk
Quality
71.1
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Pithoviridae›
Alphapithovirus›
Pithovirus_sibericum
TaxID: 1450746
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 143-242
Domain cluster:
representative
CATH (16)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3d7iB00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.67 | 48.0 | 4.92e-01 | 75.0% | 96.9% |
| 2qk2A01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.64 | 56.0 | 4.36e-01 | 100.0% | 62.0% |
| 4qhpA05 | 1.25.50.10 | Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain | 0.63 | 56.0 | 3.95e-01 | 100.0% | 34.9% |
| 3sl9B00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.59 | 52.0 | 4.47e-01 | 100.0% | 95.2% |
| 6whbA01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.58 | 49.0 | 3.68e-01 | 98.0% | 59.2% |
| 5cwkA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 50.0 | 4.28e-01 | 100.0% | 94.0% |
| 2b6cA02 | 1.25.40.290 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › ARM repeat domains | 0.56 | 46.0 | 4.64e-01 | 93.0% | 93.8% |
| 4ga6A02 | 1.20.970.50 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › | 0.56 | 45.0 | 4.06e-01 | 92.0% | 65.8% |
| 6wb9201 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 44.0 | 3.30e-01 | 91.0% | 35.6% |
| 2xqyA02 | 1.20.58.1340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 43.0 | 3.86e-01 | 89.0% | 98.6% |
| 4bwrA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.53 | 42.0 | 2.82e-01 | 89.0% | 27.8% |
| 2elcA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.53 | 34.0 | 3.88e-01 | 74.0% | 95.5% |
| 1rz4A01 | 1.25.40.250 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › ARM repeat; domain 1 | 0.53 | 43.0 | 4.15e-01 | 94.0% | 83.3% |
| 1c9bA02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.53 | 40.0 | 4.00e-01 | 83.0% | 100.0% |
| 2f07B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 42.0 | 3.44e-01 | 93.0% | 82.7% |
| 1bucA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.50 | 37.0 | 3.55e-01 | 79.0% | 95.1% |
ECOD (37)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3195802 | 109.3.1.186 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_5 | 0.83 | 71.0 | 5.07e-01 | 95.0% | 34.6% |
| 4011250 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.74 | 67.0 | 4.17e-01 | 99.0% | 30.5% |
| 3457720 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 53.0 | 5.06e-01 | 94.0% | 75.0% |
| 3463299 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.65 | 54.0 | 5.00e-01 | 93.0% | 71.5% |
| 3356967 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.64 | 54.0 | 4.69e-01 | 93.0% | 65.8% |
| 3818260 | 109.4.1.1274 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3, PPR_long | 0.61 | 53.0 | 4.83e-01 | 99.0% | 80.0% |
| 3327011 | 109.4.1.1256 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3 | 0.61 | 50.0 | 4.92e-01 | 92.0% | 83.6% |
| 3655764 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 54.0 | 4.94e-01 | 100.0% | 78.5% |
| 3352830 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.61 | 52.0 | 4.72e-01 | 96.0% | 69.6% |
| 3424787 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.60 | 52.0 | 4.48e-01 | 98.0% | 63.0% |
| 3464055 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.60 | 51.0 | 5.20e-01 | 98.0% | 97.0% |
| 3540685 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 51.0 | 3.85e-01 | 96.0% | 49.6% |
| 3830930 | 109.4.1.1277 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2, TPR_24 | 0.60 | 50.0 | 4.93e-01 | 93.0% | 91.4% |
| 3670028 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.60 | 52.0 | 4.68e-01 | 98.0% | 72.9% |
| 3669624 | 109.4.1.1293 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1 | 0.60 | 52.0 | 4.44e-01 | 98.0% | 61.8% |
| 3424603 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.60 | 51.0 | 5.15e-01 | 97.0% | 100.0% |
| 3333682 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 52.0 | 4.86e-01 | 100.0% | 92.0% |
| 3342887 | 109.4.1.189 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2 | 0.59 | 52.0 | 4.70e-01 | 100.0% | 78.6% |
| 3671482 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.59 | 48.0 | 4.51e-01 | 90.0% | 77.6% |
| 3742887 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 49.0 | 4.73e-01 | 93.0% | 80.0% |
| 3824817 | 109.4.1.1257 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2 | 0.59 | 49.0 | 4.93e-01 | 93.0% | 93.0% |
| 3454493 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.59 | 47.0 | 4.82e-01 | 95.0% | 93.7% |
| 3301571 | 109.4.1.1257 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2 | 0.58 | 48.0 | 4.77e-01 | 93.0% | 93.3% |
| 3305546 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.58 | 50.0 | 4.53e-01 | 100.0% | 74.5% |
| 3699429 | 109.4.1.72 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps16_C | 0.58 | 51.0 | 4.30e-01 | 98.0% | 66.5% |
| 3314713 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.58 | 50.0 | 4.82e-01 | 96.0% | 98.3% |
| 3460858 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.58 | 46.0 | 4.50e-01 | 90.0% | 80.0% |
| 3644152 | 109.4.1.1273 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_3 | 0.58 | 47.0 | 4.69e-01 | 93.0% | 92.4% |
| 3336721 | 109.4.1.1258 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2 | 0.58 | 50.0 | 4.87e-01 | 99.0% | 91.8% |
| 3438935 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.57 | 49.0 | 4.40e-01 | 100.0% | 66.9% |
| 3384024 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.57 | 46.0 | 4.74e-01 | 94.0% | 95.8% |
| 3680466 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.57 | 49.0 | 4.49e-01 | 100.0% | 78.5% |
| 3661550 | 109.4.1.1257 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2 | 0.56 | 46.0 | 4.68e-01 | 93.0% | 93.0% |
| 3299037 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.56 | 47.0 | 4.74e-01 | 96.0% | 95.0% |
| 3669604 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.56 | 47.0 | 4.58e-01 | 95.0% | 87.3% |
| 3299036 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.56 | 46.0 | 4.62e-01 | 93.0% | 93.0% |
| 3832196 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 45.0 | 4.46e-01 | 94.0% | 98.1% |
D2
medium
residues 278-371
Domain cluster:
representative
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ga6A02 | 1.20.970.50 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › | 0.70 | 60.0 | 5.14e-01 | 95.7% | 67.1% |
| 3hraA00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.67 | 60.0 | 4.73e-01 | 100.0% | 55.3% |
| 3t8vA05 | 1.25.50.10 | Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain | 0.66 | 54.0 | 3.67e-01 | 89.4% | 30.1% |
| 3ajcA01 | 1.10.220.30 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Flagellar motor switch protein FliG, alpha-alpha superhelical domain | 0.64 | 55.0 | 5.39e-01 | 96.8% | 91.3% |
| 4me2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 54.0 | 4.36e-01 | 100.0% | 61.3% |
| 3d7iB00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.60 | 43.0 | 4.29e-01 | 74.5% | 95.9% |
| 3e8xA00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.60 | 52.0 | 4.00e-01 | 95.7% | 89.7% |
| 2cz2A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.60 | 45.0 | 4.11e-01 | 80.9% | 91.3% |
| 3i5xA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.59 | 52.0 | 3.88e-01 | 100.0% | 51.0% |
| 4l7aA00 | 3.40.390.70 | Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › | 0.57 | 40.0 | 2.98e-01 | 74.5% | 56.7% |
| 1nnfA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.55 | 44.0 | 3.79e-01 | 88.3% | 100.0% |
| 3l9wA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.53 | 48.0 | 4.02e-01 | 100.0% | 89.0% |
| 1ct5A00 | 3.20.20.10 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase | 0.52 | 45.0 | 3.49e-01 | 100.0% | 68.4% |
| 5domA00 | 1.10.110.10 | Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins | 0.52 | 36.0 | 3.73e-01 | 74.5% | 95.6% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3254418 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.75 | 68.0 | 4.28e-01 | 100.0% | 27.1% |
| 3252179 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.72 | 64.0 | 5.75e-01 | 100.0% | 80.0% |
| 3352555 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.71 | 62.0 | 5.10e-01 | 100.0% | 57.2% |
| 3448231 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.70 | 61.0 | 5.18e-01 | 97.9% | 63.1% |
| 3701887 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 61.0 | 4.33e-01 | 100.0% | 49.2% |
| 3271594 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.68 | 60.0 | 4.15e-01 | 100.0% | 28.4% |
| 3316747 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.67 | 59.0 | 5.10e-01 | 100.0% | 70.0% |
| 3195084 | 109.4.1.1390 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF31234 | 0.62 | 54.0 | 3.94e-01 | 100.0% | 39.3% |
| 3608327 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 49.0 | 3.97e-01 | 89.4% | 52.7% |
| 3278128 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 49.0 | 4.36e-01 | 92.6% | 80.0% |
| 3257094 | 627.1.1.1 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 | 0.58 | 43.0 | 3.77e-01 | 78.7% | 63.4% |
| 3291092 | 2002.1.1.120 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM | 0.58 | 50.0 | 3.62e-01 | 97.9% | 96.4% |
| 3738445 | 109.4.1.1139 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HIR3_TPR_N | 0.52 | 44.0 | 3.45e-01 | 96.8% | 59.5% |