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ankyrin-repeat_protein

Euk-Vir

Pithovirus_sibericum

ankyrin-repeat_protein__YP_009001092__Pithovirus_sibericum__1450746

Identity

Accession:
YP_009001092 ↗
Protein ID:
ankyrin-repeat_protein
Kingdom:
euk

Quality

83.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 331-377
PDB
Domain cluster: representative
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3b7bB00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.92 85.0 5.26e-01 100.0% 27.7%
2zgdA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.91 83.0 6.42e-01 100.0% 58.8%
4cymD00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.90 82.0 5.45e-01 100.0% 37.7%
4qfvC02 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.89 78.0 6.93e-01 95.7% 83.1%
3lvqE03 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.88 77.0 7.08e-01 95.7% 91.5%
1wdyA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.88 79.0 4.78e-01 100.0% 21.8%
5h28A01 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.88 79.0 5.46e-01 100.0% 41.4%
1qymA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.88 79.0 4.95e-01 100.0% 27.8%
3ehrA02 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.87 77.0 5.69e-01 97.9% 50.0%
3lvqE02 1.25.40.950 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.84 72.0 6.23e-01 97.9% 86.5%
5c8aA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.69 59.0 5.07e-01 100.0% 89.7%
1wy6A00 1.25.40.350 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.65 52.0 3.80e-01 100.0% 39.0%
1vx7301 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 44.0 3.85e-01 72.3% 75.7%
4tktA02 1.10.1240.100 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.63 42.0 3.62e-01 70.2% 40.2%
2wwwC01 1.20.5.170 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.61 42.0 4.15e-01 74.5% 90.4%
2hpiA01 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.60 52.0 3.26e-01 100.0% 44.7%
1n0uA03 3.90.1430.10 Alpha Beta › Alpha-Beta Complex › Yeast translation eEF2 (G' domain) › Yeast translation eEF2 (G' domain) 0.56 48.0 3.68e-01 97.9% 42.1%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3267273 109.3.1.8 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2 0.92 85.0 6.18e-01 100.0% 45.2%
3992104 109.3.1.96 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 0.92 85.0 4.83e-01 100.0% 14.8%
3275803 109.3.1.96 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 0.92 84.0 4.78e-01 100.0% 12.2%
3899599 109.3.1.164 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_3, Ank_4 0.91 83.0 5.26e-01 100.0% 29.5%
4080477 109.3.1.2 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.91 83.0 5.37e-01 100.0% 32.6%
3198211 109.3.1.347 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_KRIT1 0.90 82.0 4.76e-01 100.0% 13.9%
4891160 109.3.1.162 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_5 0.90 82.0 7.60e-01 100.0% 98.3%
3695738 109.3.1.232 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_4, Ank_KRIT1 0.89 81.0 4.60e-01 100.0% 12.3%
3263008 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.86 77.0 4.77e-01 100.0% 20.0%
3724862 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.85 75.0 5.15e-01 100.0% 32.3%
3575749 109.3.1.1 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank 0.83 70.0 4.93e-01 93.6% 40.7%
3297911 109.4.1.883 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.76 65.0 4.20e-01 100.0% 30.2%
3367156 109.4.1.883 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.74 63.0 4.36e-01 100.0% 36.5%
3425838 109.4.1.883 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.72 60.0 3.81e-01 97.9% 24.9%
3981167 4995.1.1.3 alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › MlrA_helical 0.67 57.0 4.94e-01 97.9% 88.0%
3393127 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 52.0 3.59e-01 89.4% 91.2%
3543692 226.1.1.1 a+b two layers › POZ domain › POZ domain › POZ domain › BTB 0.66 54.0 3.93e-01 100.0% 34.7%
3611632 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.56 38.0 3.06e-01 72.3% 100.0%
D3 medium residues 227-330
PDB
CATH (19)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4hi8A00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.72 60.0 5.04e-01 99.0% 54.1%
3eu9C00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.72 65.0 4.92e-01 100.0% 44.2%
4leuA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 53.0 4.39e-01 100.0% 58.8%
8sorA01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.58 51.0 3.61e-01 100.0% 40.6%
5z62E00 1.25.40.40 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Cytochrome c oxidase, subunit Va/VI 0.58 45.0 4.49e-01 98.1% 81.7%
6t0bf00 1.25.40.40 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Cytochrome c oxidase, subunit Va/VI 0.58 46.0 4.71e-01 98.1% 90.2%
2qw6D00 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.56 34.0 3.69e-01 99.0% 73.3%
2raeA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 39.0 3.62e-01 76.9% 84.7%
4xi0F00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 40.0 3.44e-01 100.0% 47.8%
2l1lB00 1.20.1440.250 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.53 45.0 4.27e-01 97.1% 89.0%
2f07B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 41.0 3.37e-01 84.6% 82.1%
6u3wB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 42.0 3.14e-01 90.4% 64.6%
4rflA02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.52 45.0 3.72e-01 100.0% 91.5%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 42.0 3.79e-01 93.3% 81.2%
4gtnA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.51 33.0 3.75e-01 76.0% 91.9%
6nmnA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.51 35.0 3.31e-01 92.3% 57.8%
6mcjA00 1.10.2090.10 Mainly Alpha › Orthogonal Bundle › orange carotenoid protein, domain 2 › Orange carotenoid-binding protein, N-terminal domain 0.51 36.0 3.30e-01 75.0% 69.0%
4xvxA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.51 36.0 3.60e-01 76.0% 90.1%
2di3B02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.50 35.0 3.19e-01 74.0% 83.9%
ECOD (43)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3260808 109.3.1.8 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2 0.85 65.0 4.73e-01 100.0% 32.5%
3252035 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.84 69.0 5.86e-01 100.0% 55.6%
4306725 109.3.1.20 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2,Ank_4 0.82 65.0 4.73e-01 100.0% 33.1%
3259472 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.80 61.0 5.73e-01 99.0% 66.4%
3370231 109.3.1.2 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.79 67.0 6.28e-01 100.0% 74.2%
4001612 109.3.1.2 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.76 65.0 5.49e-01 100.0% 58.1%
4256934 109.3.1.165 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_3, Ank_4, Ank_5 0.76 71.0 4.36e-01 100.0% 20.5%
3247851 109.3.1.33 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2,Ank_3 0.75 70.0 5.95e-01 100.0% 68.1%
3255754 109.3.1.8 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2 0.74 67.0 4.29e-01 100.0% 23.3%
3619592 109.3.1.2 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.73 63.0 4.48e-01 100.0% 33.2%
3257618 109.3.1.171 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › PF29011 0.72 58.0 5.01e-01 97.1% 56.2%
4019164 109.3.1.218 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_KRIT1 0.71 60.0 4.85e-01 100.0% 50.3%
4524456 109.3.1.165 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_3, Ank_4, Ank_5 0.70 65.0 3.97e-01 100.0% 19.9%
3257073 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.69 54.0 4.88e-01 99.0% 61.4%
3267790 109.3.1.171 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › PF29011 0.69 59.0 4.95e-01 100.0% 55.9%
3260857 109.3.1.171 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › PF29011 0.67 63.0 4.66e-01 100.0% 45.3%
3350178 109.4.1.1293 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1 0.66 54.0 4.12e-01 100.0% 39.1%
3271400 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.65 60.0 4.48e-01 100.0% 48.2%
3253180 109.3.1.171 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › PF29011 0.65 60.0 4.65e-01 100.0% 52.6%
3328896 109.4.1.3010 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Eplus_motif, E_motif 0.64 50.0 4.42e-01 100.0% 56.8%
3276358 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.64 58.0 3.81e-01 98.1% 24.9%
3254419 109.3.1.171 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › PF29011 0.63 58.0 4.41e-01 100.0% 49.4%
3262021 109.3.1.171 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › PF29011 0.63 56.0 4.76e-01 99.0% 61.8%
3721073 109.3.1.2 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.62 57.0 5.24e-01 100.0% 88.9%
3436850 109.4.1.1269 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, E_motif 0.61 47.0 4.77e-01 100.0% 81.9%
3647434 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 47.0 4.77e-01 99.0% 84.0%
3679150 109.4.1.1285 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, DYW_deaminase, Eplus_motif, E_motif 0.59 51.0 3.36e-01 100.0% 21.2%
3817872 109.4.1.883 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.58 52.0 4.06e-01 99.0% 51.6%
3196469 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 51.0 4.80e-01 100.0% 83.1%
3806181 109.4.1.420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.58 46.0 4.35e-01 100.0% 70.0%
3279812 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.58 40.0 3.66e-01 73.1% 83.4%
3950431 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.56 40.0 3.64e-01 73.1% 85.7%
3324677 109.4.1.1271 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, TPR_24 0.56 46.0 3.89e-01 100.0% 53.1%
3388639 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.55 44.0 4.03e-01 86.5% 83.6%
3984797 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 48.0 3.61e-01 100.0% 89.6%
3339436 109.4.1.1262 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_long 0.54 48.0 4.44e-01 100.0% 79.3%
3735475 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 42.0 4.16e-01 97.1% 80.9%
3309352 109.4.1.1271 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, TPR_24 0.53 47.0 4.03e-01 100.0% 62.4%
3804467 109.4.1.883 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.53 47.0 3.86e-01 100.0% 53.5%
3655765 109.4.1.1254 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.53 47.0 3.45e-01 100.0% 36.8%
5008061 1075.1.1.67 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › 12TM_1 0.53 43.0 3.58e-01 90.4% 87.7%
3324519 109.4.1.777 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 39.0 3.99e-01 96.2% 85.7%
4950248 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.51 38.0 4.00e-01 82.7% 93.7%