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ankyrin-repeat_protein
Euk-VirPithovirus_sibericum
ankyrin-repeat_protein__YP_009001249__Pithovirus_sibericum__1450746
Identity
- Accession:
- YP_009001249 ↗
- Protein ID:
- ankyrin-repeat_protein
- Kingdom:
- euk
Quality
74.9
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Pithoviridae›
Alphapithovirus›
Pithovirus_sibericum
TaxID: 1450746
Cluster
View cluster (3 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 169-254
Domain cluster:
representative
CATH (63)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5kc8A02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.66 | 53.0 | 4.34e-01 | 88.4% | 65.4% |
| 3fbgA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.64 | 45.0 | 3.78e-01 | 82.6% | 42.9% |
| 4ceiB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.64 | 53.0 | 4.25e-01 | 94.2% | 73.9% |
| 2b4lA02 | 3.10.105.10 | Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 | 0.64 | 47.0 | 3.86e-01 | 77.9% | 60.5% |
| 2p4gA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.62 | 47.0 | 3.38e-01 | 81.4% | 34.3% |
| 3qyfA01 | 3.40.50.10770 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Hypothetical protein VC1899 like domain (Restriction endonuclease-like) | 0.61 | 46.0 | 3.70e-01 | 80.2% | 90.9% |
| 2yk4A01 | 3.30.370.20 | Alpha Beta › 2-Layer Sandwich › Barnase; Chain D › | 0.59 | 41.0 | 4.20e-01 | 79.1% | 75.6% |
| 4bxoA01 | 3.40.50.10130 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.59 | 44.0 | 3.83e-01 | 79.1% | 57.0% |
| 2amlB01 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.59 | 50.0 | 3.76e-01 | 94.2% | 42.3% |
| 4c0rA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.59 | 32.0 | 3.03e-01 | 79.1% | 42.2% |
| 3hbaA01 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.59 | 50.0 | 3.88e-01 | 94.2% | 47.6% |
| 4zeoH02 | 3.40.50.10470 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Translation initiation factor eif-2b; domain 2 | 0.58 | 50.0 | 4.08e-01 | 96.5% | 81.2% |
| 1eamA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.57 | 49.0 | 3.49e-01 | 98.8% | 54.7% |
| 3g68B01 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.57 | 48.0 | 3.69e-01 | 94.2% | 44.2% |
| 2efjA02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.57 | 44.0 | 3.30e-01 | 82.6% | 36.9% |
| 3vasA01 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.57 | 49.0 | 3.47e-01 | 97.7% | 52.5% |
| 2wjwA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 46.0 | 3.78e-01 | 89.5% | 64.4% |
| 1dgmA01 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.57 | 48.0 | 3.43e-01 | 96.5% | 51.4% |
| 3slrA01 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.57 | 46.0 | 3.55e-01 | 93.0% | 61.3% |
| 3c3jA01 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.56 | 49.0 | 3.77e-01 | 97.7% | 50.0% |
| 1y0bB01 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.56 | 45.0 | 3.67e-01 | 93.0% | 61.7% |
| 2l69A00 | 3.40.50.11230 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.56 | 41.0 | 3.61e-01 | 93.0% | 50.7% |
| 2dfjA00 | 3.60.21.10 | Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases | 0.56 | 47.0 | 3.42e-01 | 97.7% | 37.1% |
| 1pzmA00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.55 | 46.0 | 3.74e-01 | 93.0% | 55.3% |
| 3geeA03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 39.0 | 3.47e-01 | 75.6% | 81.2% |
| 1jceA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.55 | 38.0 | 3.26e-01 | 73.3% | 82.4% |
| 3lkbA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.55 | 44.0 | 3.63e-01 | 88.4% | 76.6% |
| 3fj1A01 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.55 | 47.0 | 3.68e-01 | 96.5% | 47.7% |
| 2xblD00 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.55 | 47.0 | 3.68e-01 | 97.7% | 57.4% |
| 6whjD00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.55 | 48.0 | 3.32e-01 | 100.0% | 27.7% |
| 4f1jA00 | 3.40.50.410 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain | 0.54 | 46.0 | 3.60e-01 | 97.7% | 81.0% |
| 3gdwB00 | 3.40.50.510 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component | 0.54 | 39.0 | 3.37e-01 | 75.6% | 87.7% |
| 3wnvA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.54 | 41.0 | 3.23e-01 | 81.4% | 43.2% |
| 1jmkC01 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.54 | 45.0 | 3.69e-01 | 95.3% | 77.3% |
| 4c7oA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 46.0 | 3.66e-01 | 100.0% | 50.0% |
| 4imrB00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.54 | 45.0 | 3.32e-01 | 96.5% | 61.7% |
| 1usgA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.54 | 44.0 | 3.72e-01 | 89.5% | 80.6% |
| 5lddC00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 44.0 | 3.65e-01 | 94.2% | 79.2% |
| 4n03A02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.54 | 42.0 | 3.37e-01 | 84.9% | 73.3% |
| 5l3qA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 46.0 | 3.58e-01 | 100.0% | 47.6% |
| 6yttA02 | 3.40.50.2030 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.54 | 47.0 | 3.80e-01 | 100.0% | 85.3% |
| 6a6eA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.53 | 46.0 | 3.29e-01 | 96.5% | 37.2% |
| 1o9gA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.53 | 44.0 | 3.42e-01 | 94.2% | 60.7% |
| 3imkA00 | 3.40.50.450 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.53 | 40.0 | 3.31e-01 | 80.2% | 64.6% |
| 3vpbA01 | 3.40.50.20 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.53 | 41.0 | 3.95e-01 | 84.9% | 91.1% |
| 3kksB00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.53 | 37.0 | 3.10e-01 | 72.1% | 53.3% |
| 3om0A02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.53 | 44.0 | 3.65e-01 | 94.2% | 81.2% |
| 1xngA01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.53 | 44.0 | 3.27e-01 | 96.5% | 89.9% |
| 7bmfA01 | 3.90.1640.30 | Alpha Beta › Alpha-Beta Complex › inorganic pyrophosphatase (n-terminal core) › | 0.53 | 38.0 | 2.95e-01 | 74.4% | 80.5% |
| 2wqpA01 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.53 | 46.0 | 3.28e-01 | 98.8% | 33.9% |
| 6yb3A01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 43.0 | 3.24e-01 | 94.2% | 55.7% |
| 4wzzA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.52 | 40.0 | 3.36e-01 | 84.9% | 85.5% |
| 2gruA01 | 3.40.50.1970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.52 | 43.0 | 3.54e-01 | 94.2% | 71.8% |
| 5fbhA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.52 | 44.0 | 3.50e-01 | 96.5% | 52.4% |
| 2fi9A00 | 3.40.1230.10 | Alpha Beta › 3-Layer(aba) Sandwich › Hypothetical Protein Mth938; Chain: A, › MTH938-like | 0.52 | 36.0 | 3.32e-01 | 77.9% | 53.4% |
| 3caiA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.51 | 43.0 | 3.19e-01 | 97.7% | 40.9% |
| 4bjhB01 | 3.40.50.1370 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase | 0.51 | 38.0 | 3.21e-01 | 79.1% | 47.6% |
| 1duvG01 | 3.40.50.1370 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase | 0.51 | 39.0 | 3.30e-01 | 81.4% | 52.7% |
| 3zrpA01 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.51 | 44.0 | 3.23e-01 | 100.0% | 55.0% |
| 1eluA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.51 | 44.0 | 3.16e-01 | 97.7% | 40.5% |
| 4dgsA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.51 | 38.0 | 3.22e-01 | 81.4% | 47.7% |
| 4igiA00 | 3.40.50.410 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain | 0.51 | 42.0 | 3.38e-01 | 97.7% | 100.0% |
| 2gsdA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.50 | 41.0 | 3.26e-01 | 98.8% | 41.7% |
ECOD (66)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4382819 | 301.1.1.8 ↗ | a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › PELOTA_1 | 0.61 | 38.0 | 3.69e-01 | 77.9% | 55.8% |
| 3949174 | 7523.1.1.3 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_5 | 0.60 | 45.0 | 3.37e-01 | 79.1% | 46.8% |
| 5024852 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.60 | 42.0 | 3.66e-01 | 74.4% | 59.3% |
| 5066062 | 7584.1.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding | 0.59 | 49.0 | 4.17e-01 | 94.2% | 68.7% |
| 3622925 | 7590.1.1.2 ↗ | a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi | 0.59 | 42.0 | 3.28e-01 | 74.4% | 51.1% |
| 3744374 | 2006.1.2.3 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › CDC45 | 0.59 | 46.0 | 3.12e-01 | 83.7% | 95.2% |
| 4947102 | 2006.1.2.8 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH_CID | 0.59 | 45.0 | 3.21e-01 | 81.4% | 90.4% |
| 5000617 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.58 | 44.0 | 3.18e-01 | 81.4% | 91.9% |
| 1289700 | 2007.6.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › SIS | 0.58 | 50.0 | 3.98e-01 | 96.5% | 51.4% |
| 3285481 | 7573.1.1.6 ↗ | a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › TRSP | 0.58 | 41.0 | 3.18e-01 | 74.4% | 59.5% |
| 4983146 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.58 | 44.0 | 3.19e-01 | 81.4% | 92.8% |
| 4870619 | 2003.1.7.2 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › IF-2B | 0.58 | 43.0 | 3.73e-01 | 81.4% | 49.3% |
| 4968670 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.58 | 44.0 | 3.15e-01 | 81.4% | 92.4% |
| 1138365 | 2007.6.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › SIS | 0.57 | 48.0 | 3.89e-01 | 94.2% | 52.6% |
| 3592079 | 7590.1.1.0 ↗ | a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs | 0.57 | 40.0 | 3.29e-01 | 73.3% | 63.5% |
| 4022117 | 2006.1.2.3 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › CDC45 | 0.57 | 44.0 | 2.91e-01 | 83.7% | 95.1% |
| 4932675 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.57 | 43.0 | 3.17e-01 | 81.4% | 92.2% |
| 5053872 | 2006.1.2.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases | 0.57 | 43.0 | 3.12e-01 | 81.4% | 75.4% |
| 5083164 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.57 | 41.0 | 3.68e-01 | 76.7% | 71.2% |
| 4972064 | 2007.6.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › SIS | 0.57 | 49.0 | 3.99e-01 | 97.7% | 54.1% |
| 5081764 | 300.1.1.7 ↗ | a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › PP_kinase_C | 0.57 | 45.0 | 3.70e-01 | 86.0% | 48.8% |
| 4994258 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.57 | 43.0 | 3.10e-01 | 80.2% | 89.4% |
| 3188709 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.57 | 42.0 | 3.53e-01 | 81.4% | 65.0% |
| 3717378 | 2005.1.1.18 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › NAD_synthase | 0.56 | 42.0 | 3.04e-01 | 82.6% | 28.5% |
| 5032111 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.56 | 43.0 | 3.10e-01 | 82.6% | 90.8% |
| 3170000 | 2004.1.1.103 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Sua5_C | 0.56 | 40.0 | 3.46e-01 | 74.4% | 66.7% |
| 5060749 | 2007.1.1.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like | 0.56 | 46.0 | 3.37e-01 | 97.7% | 30.6% |
| 5025730 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.56 | 41.0 | 2.94e-01 | 79.1% | 90.2% |
| 4935979 | 2004.1.1.90 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CobA_CobO_BtuR | 0.56 | 47.0 | 3.74e-01 | 93.0% | 66.9% |
| 4152326 | 2004.1.1.187 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DNA_pol3_delta2 | 0.56 | 47.0 | 4.10e-01 | 97.7% | 60.0% |
| 3720227 | 7590.1.1.0 ↗ | a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs | 0.56 | 39.0 | 3.21e-01 | 73.3% | 59.4% |
| None | — | 0.56 | 47.0 | 3.61e-01 | 100.0% | 43.0% | |
| 5082334 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.55 | 41.0 | 2.99e-01 | 79.1% | 91.8% |
| 3287922 | 2007.1.2.11 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_4 | 0.55 | 43.0 | 3.66e-01 | 86.0% | 85.3% |
| 4945956 | 2004.1.1.43 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54 | 0.55 | 47.0 | 3.64e-01 | 98.8% | 46.7% |
| 3657617 | 2007.1.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › GATase | 0.55 | 48.0 | 3.43e-01 | 100.0% | 57.1% |
| None | — | 0.55 | 47.0 | 3.59e-01 | 100.0% | 44.1% | |
| 4117291 | 2004.1.1.43 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54 | 0.55 | 47.0 | 3.62e-01 | 100.0% | 46.7% |
| 3346014 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.55 | 41.0 | 2.93e-01 | 82.6% | 26.2% |
| 3279344 | 2007.5.1.15 ↗ | a/b three-layered sandwiches › Flavodoxin-like › SGNH hydrolase › SGNH hydrolase › FkbH_N | 0.54 | 46.0 | 3.43e-01 | 97.7% | 51.7% |
| 4946985 | 2004.1.1.43 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54 | 0.54 | 47.0 | 3.56e-01 | 100.0% | 43.6% |
| 5047453 | 2006.1.2.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases | 0.54 | 41.0 | 3.02e-01 | 81.4% | 93.0% |
| None | — | 0.54 | 46.0 | 3.57e-01 | 100.0% | 48.8% | |
| 5052019 | 2006.1.2.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases | 0.54 | 45.0 | 3.20e-01 | 93.0% | 38.5% |
| 5008472 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.54 | 39.0 | 2.83e-01 | 77.9% | 88.1% |
| 3189839 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.54 | 38.0 | 3.23e-01 | 75.6% | 63.9% |
| 4348087 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.53 | 46.0 | 3.11e-01 | 100.0% | 27.9% |
| 4018513 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.53 | 39.0 | 3.30e-01 | 79.1% | 63.9% |
| 119404 | 7563.1.1.5 ↗ | a/b three-layered sandwiches › MCP/YpsA-related › MCP/YpsA-related › MCP/YpsA-related › cpYpsA | 0.53 | 40.0 | 3.31e-01 | 80.2% | 64.6% |
| None | — | 0.53 | 45.0 | 3.42e-01 | 100.0% | 66.1% | |
| 4118994 | 2007.1.7.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Rossmann-like domain in dehydroquinate synthase-like enzymes › DHQ_synthase | 0.53 | 43.0 | 3.51e-01 | 93.0% | 59.4% |
| 3601015 | 2006.1.2.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases | 0.52 | 41.0 | 2.84e-01 | 88.4% | 44.6% |
| 3597780 | 2008.1.1.31 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › VRR_NUC | 0.52 | 39.0 | 2.80e-01 | 77.9% | 81.2% |
| 3957458 | 7512.1.1.32 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_1_4 | 0.52 | 46.0 | 3.51e-01 | 100.0% | 54.3% |
| 4146807 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.52 | 37.0 | 3.18e-01 | 75.6% | 55.7% |
| 4253395 | 2005.1.1.18 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › NAD_synthase | 0.52 | 43.0 | 3.22e-01 | 97.7% | 81.9% |
| 4103037 | 2007.1.7.3 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Rossmann-like domain in dehydroquinate synthase-like enzymes › Fe-ADH_2 | 0.51 | 42.0 | 3.52e-01 | 94.2% | 58.7% |
| 5048834 | 2006.1.4.3 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN | 0.51 | 42.0 | 3.48e-01 | 93.0% | 86.1% |
| 5031003 | 2006.1.4.3 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN | 0.51 | 42.0 | 3.47e-01 | 93.0% | 65.5% |
| 4943536 | 2003.1.14.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Aspartate/ornithine carbamoyltransferase › OTCace | 0.50 | 38.0 | 3.24e-01 | 82.6% | 53.3% |
| 3345347 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.50 | 38.0 | 3.19e-01 | 80.2% | 49.3% |
| 5055136 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.50 | 37.0 | 2.73e-01 | 79.1% | 40.4% |
| 4408117 | 2003.1.14.2 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Aspartate/ornithine carbamoyltransferase › OTCace_N | 0.50 | 37.0 | 3.61e-01 | 79.1% | 77.0% |
| 4956217 | 2005.1.1.0 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains | 0.50 | 41.0 | 3.28e-01 | 93.0% | 79.9% |
| 4962923 | 7590.1.1.1 ↗ | a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Peptidase_M29 | 0.50 | 38.0 | 3.20e-01 | 83.7% | 75.0% |
| 3984567 | 2484.1.1.127 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve_2 | 0.50 | 35.0 | 3.28e-01 | 77.9% | 56.5% |
D2
medium
residues 255-329
Domain cluster:
representative
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.65 | 45.0 | 3.88e-01 | 72.0% | 88.0% |
| 4kzsA02 | 6.10.140.1870 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 45.0 | 4.61e-01 | 78.7% | 95.7% |
| 4id0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.59 | 49.0 | 4.37e-01 | 96.0% | 89.3% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 43.0 | 3.64e-01 | 82.7% | 73.1% |
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.55 | 38.0 | 3.58e-01 | 72.0% | 80.4% |
| 1vw4T01 | 6.10.330.20 | Special › Helix non-globular › Monooxygenase › | 0.54 | 43.0 | 3.84e-01 | 89.3% | 72.3% |
| 4a17U01 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 37.0 | 3.67e-01 | 70.7% | 85.7% |
| 1gpjA03 | 1.10.1200.70 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glutamyl tRNA-reductase dimerization domain | 0.53 | 30.0 | 2.89e-01 | 89.3% | 45.9% |
| 3mvpA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 41.0 | 3.42e-01 | 88.0% | 64.4% |
| 1euhA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.53 | 45.0 | 3.16e-01 | 100.0% | 32.8% |
| 2g7lA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 42.0 | 3.22e-01 | 92.0% | 63.2% |
| 1x9mA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.52 | 42.0 | 3.10e-01 | 94.7% | 97.3% |
| 1m56C02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.51 | 36.0 | 2.80e-01 | 77.3% | 46.9% |
| 3t57A02 | 1.20.1180.10 | Mainly Alpha › Up-down Bundle › Udp N-acetylglucosamine O-acyltransferase; Domain 2 › Udp N-acetylglucosamine O-acyltransferase, C-terminal domain | 0.51 | 34.0 | 3.44e-01 | 72.0% | 69.3% |
| 5cqgA03 | 1.10.10.2210 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.50 | 34.0 | 3.44e-01 | 72.0% | 89.9% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3276098 | 109.3.1.96 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 | 0.75 | 68.0 | 4.14e-01 | 98.7% | 16.8% |
| 3201325 | 109.3.1.11 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_5 | 0.63 | 55.0 | 4.06e-01 | 98.7% | 37.6% |
| 3570625 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.61 | 42.0 | 3.97e-01 | 72.0% | 82.2% |
| 3870316 | 150.3.1.10 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › CNTF | 0.60 | 42.0 | 3.20e-01 | 72.0% | 72.2% |
| 5057999 | 7516.1.1.79 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_trans_2_3 | 0.60 | 44.0 | 2.80e-01 | 92.0% | 14.7% |
| 3592211 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.58 | 41.0 | 3.74e-01 | 77.3% | 77.3% |
| 3458691 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.57 | 47.0 | 3.91e-01 | 96.0% | 53.1% |
| 4950367 | 622.1.1.0 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain | 0.55 | 38.0 | 3.24e-01 | 70.7% | 62.3% |
| 3288623 | 191.1.1.35 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_35 | 0.54 | 42.0 | 3.63e-01 | 86.7% | 80.0% |
| 3496372 | 5076.2.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ | 0.50 | 35.0 | 2.58e-01 | 76.0% | 96.3% |
D3
medium
residues 330-418
Domain cluster:
representative
CATH (16)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4xaxB02 | 1.20.58.1290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain | 0.71 | 61.0 | 5.88e-01 | 97.8% | 82.8% |
| 3on4D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.70 | 61.0 | 4.76e-01 | 94.4% | 75.1% |
| 3e7qA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.69 | 56.0 | 4.22e-01 | 87.6% | 64.9% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.68 | 47.0 | 4.39e-01 | 70.8% | 93.7% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 48.0 | 4.30e-01 | 75.3% | 85.2% |
| 2dg7A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.66 | 54.0 | 4.14e-01 | 86.5% | 72.0% |
| 1q6aA00 | 1.10.1240.30 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain | 0.66 | 51.0 | 4.83e-01 | 84.3% | 89.7% |
| 2np5D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 56.0 | 4.63e-01 | 100.0% | 76.6% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.62 | 43.0 | 3.66e-01 | 71.9% | 55.1% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.61 | 44.0 | 3.66e-01 | 75.3% | 69.3% |
| 5k29A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.60 | 41.0 | 4.04e-01 | 70.8% | 76.3% |
| 2aw6A02 | 1.25.40.400 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.59 | 48.0 | 3.63e-01 | 100.0% | 35.7% |
| 2ii2A04 | 1.10.220.10 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin | 0.58 | 45.0 | 4.78e-01 | 97.8% | 94.9% |
| 2gx5C00 | 3.30.450.40 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain | 0.54 | 38.0 | 3.09e-01 | 71.9% | 82.6% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.52 | 44.0 | 3.99e-01 | 91.0% | 92.4% |
| 2kxpA01 | 3.30.1140.60 | Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › F-actin capping protein, alpha subunit | 0.50 | 40.0 | 3.78e-01 | 86.5% | 86.0% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3941249 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.70 | 50.0 | 4.79e-01 | 73.0% | 97.0% |
| 4002712 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.70 | 49.0 | 4.00e-01 | 71.9% | 53.8% |
| 3286008 | 5050.1.1.52 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › CNNM | 0.68 | 47.0 | 3.85e-01 | 71.9% | 67.9% |
| 3454947 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.67 | 47.0 | 3.38e-01 | 73.0% | 51.2% |
| 3750022 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.65 | 45.0 | 4.20e-01 | 71.9% | 90.9% |
| 3493417 | 4163.1.1.1 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 | 0.64 | 51.0 | 4.22e-01 | 86.5% | 78.1% |
| 4619619 | 109.3.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank | 0.62 | 53.0 | 4.12e-01 | 94.4% | 65.1% |
| 3482273 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.62 | 43.0 | 4.01e-01 | 71.9% | 89.0% |
| 3397045 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 47.0 | 4.13e-01 | 88.8% | 84.1% |
| 3596083 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.57 | 46.0 | 4.07e-01 | 91.0% | 90.7% |
| 4992531 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.57 | 40.0 | 3.67e-01 | 73.0% | 95.8% |
| 3211680 | 109.7.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E | 0.51 | 41.0 | 4.18e-01 | 100.0% | 94.4% |