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ankyrin_repeat_protein
Euk-VirCotia_virus_SPAn232
ankyrin_repeat_protein__YP_005296204__Cotia_virus_SPAn232__930275
Identity
- Accession:
- YP_005296204 ↗
- Protein ID:
- ankyrin_repeat_protein
- Kingdom:
- euk
Quality
86.1
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Oryzopoxvirus›
Cotia_virus_SPAn232
TaxID: 930275
Cluster
View cluster (144 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 500-580
Domain cluster:
rep: ankyrin_repeat_protein__YP_009046215__Penguinpox_virus__648998__D344-440
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF09372.16 best | PRANC | 41.4 | 2.00e-10 | 98.8% | 80.4% |
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3cf6E01 | 1.10.8.1240 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.76 | 36.0 | 4.77e-01 | 84.0% | 82.2% |
| 3s63A00 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.76 | 40.0 | 3.93e-01 | 86.4% | 48.9% |
| 4alyB00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.73 | 54.0 | 4.10e-01 | 77.8% | 39.0% |
| 3onjA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.69 | 47.0 | 4.43e-01 | 70.4% | 63.9% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.68 | 47.0 | 4.32e-01 | 71.6% | 92.2% |
| 2x4hA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.67 | 58.0 | 5.00e-01 | 96.3% | 87.6% |
| 4hteA01 | 1.20.58.1730 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 48.0 | 3.98e-01 | 75.3% | 62.2% |
| 3zojA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.62 | 43.0 | 3.04e-01 | 72.8% | 40.7% |
| 3bg2A02 | 1.10.3550.10 | Mainly Alpha › Orthogonal Bundle › eoxyguanosinetriphosphate triphosphohydrolase fold › eoxyguanosinetriphosphate triphosphohydrolase domain-like | 0.61 | 52.0 | 4.70e-01 | 95.1% | 99.1% |
| 4fzlA01 | 1.10.150.790 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.56 | 50.0 | 4.89e-01 | 98.8% | 94.3% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.54 | 43.0 | 3.33e-01 | 87.7% | 95.7% |
| 1f5qB02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.51 | 45.0 | 3.71e-01 | 93.8% | 65.9% |
| 3iieB03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.51 | 40.0 | 3.99e-01 | 90.1% | 83.5% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4142281 | 105.1.1.55 ↗ | alpha duplicates or obligate multimers › HLH-like › HLH, helix-loop-helix DNA-binding domain › HLH, helix-loop-helix DNA-binding domain › Latarcin | 0.78 | 51.0 | 4.85e-01 | 70.4% | 57.4% |
| 3972755 | 601.1.2.99 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DAGK_prokar | 0.71 | 54.0 | 4.68e-01 | 79.0% | 60.2% |
| 4979868 | 5076.2.1.13 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › DUF7847 | 0.69 | 55.0 | 3.95e-01 | 87.7% | 59.8% |
| 3167538 | 603.1.1.3 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE | 0.69 | 47.0 | 4.15e-01 | 70.4% | 53.9% |
| 5048220 | 5076.2.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ | 0.66 | 55.0 | 3.83e-01 | 91.4% | 87.0% |
| 3252817 | 1025.1.1.0 ↗ | alpha bundles › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin helical domain | 0.65 | 48.0 | 4.41e-01 | 77.8% | 68.6% |
| 5025290 | 101.1.2.652 ↗ | alpha arrays › HTH › HTH › winged helix domain › Fe_dep_repr_C | 0.64 | 56.0 | 4.83e-01 | 98.8% | 83.1% |
| 3411860 | 633.6.1.6 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C | 0.64 | 49.0 | 4.00e-01 | 82.7% | 50.7% |
| 4963316 | 247.1.1.1 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B | 0.62 | 50.0 | 3.54e-01 | 88.9% | 33.1% |
| 4949793 | 101.1.2.652 ↗ | alpha arrays › HTH › HTH › winged helix domain › Fe_dep_repr_C | 0.62 | 55.0 | 4.72e-01 | 100.0% | 86.2% |
| 5067264 | 101.1.2.21 ↗ | alpha arrays › HTH › HTH › winged helix domain › Fe_dep_repress | 0.60 | 52.0 | 4.61e-01 | 98.8% | 91.7% |
| 3688745 | 5001.1.1.53 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › LMBR1 | 0.60 | 45.0 | 2.98e-01 | 79.0% | 44.2% |
| 5024880 | 7014.1.1.2 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE | 0.57 | 43.0 | 3.86e-01 | 81.5% | 86.1% |
| 3974805 | 2498.1.1.71 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Aminopep | 0.52 | 44.0 | 3.05e-01 | 100.0% | 75.4% |
| 3956417 | 7552.1.1.1 ↗ | a/b three-layered sandwiches › Amidase signature (AS) enzymes › Amidase signature (AS) enzymes › Amidase signature (AS) enzymes › Amidase | 0.51 | 40.0 | 2.50e-01 | 86.4% | 59.8% |
| 3958441 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.51 | 42.0 | 3.60e-01 | 92.6% | 57.6% |
D2
medium
residues 1-62
Domain cluster:
representative
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3lvqE02 | 1.25.40.950 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.84 | 75.0 | 7.05e-01 | 98.4% | 93.2% |
| 4n5qA00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.79 | 70.0 | 4.61e-01 | 100.0% | 34.9% |
| 1wdyA00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.78 | 70.0 | 4.48e-01 | 100.0% | 37.2% |
| 3eu9C00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.78 | 69.0 | 4.66e-01 | 100.0% | 29.2% |
| 2rfmB00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.77 | 68.0 | 4.82e-01 | 100.0% | 35.3% |
| 3uxgA00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.74 | 65.0 | 4.79e-01 | 100.0% | 39.9% |
| 4evfA02 | 1.10.220.10 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin | 0.68 | 55.0 | 5.25e-01 | 91.9% | 95.9% |
| 8hk0A01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.61 | 44.0 | 3.65e-01 | 79.0% | 69.7% |
| 2c5iT00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 45.0 | 3.93e-01 | 80.6% | 85.1% |
| 4ivfA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 45.0 | 3.88e-01 | 100.0% | 85.3% |
| 1bxgA01 | 3.40.50.10860 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1 | 0.52 | 42.0 | 3.47e-01 | 100.0% | 82.2% |
| 1jmwA00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.51 | 37.0 | 2.96e-01 | 80.6% | 61.0% |
| 3uitA02 | 1.20.1270.460 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.51 | 40.0 | 3.37e-01 | 95.2% | 67.7% |
| 3iu5A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.51 | 35.0 | 2.97e-01 | 74.2% | 71.1% |
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3217523 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.82 | 73.0 | 5.01e-01 | 100.0% | 46.2% |
| 4020229 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.79 | 72.0 | 6.61e-01 | 100.0% | 84.6% |
| 3388566 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.78 | 70.0 | 4.47e-01 | 100.0% | 43.6% |
| 4222893 | 109.3.1.164 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_3, Ank_4 | 0.78 | 66.0 | 4.63e-01 | 98.4% | 30.9% |
| 3706174 | 109.3.1.170 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_4 | 0.76 | 68.0 | 5.02e-01 | 100.0% | 42.5% |
| 3927965 | 109.3.1.33 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2,Ank_3 | 0.73 | 64.0 | 5.40e-01 | 100.0% | 67.6% |
| 3733316 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.68 | 60.0 | 5.65e-01 | 100.0% | 81.3% |
| 4029678 | 4984.1.1.0 ↗ | alpha bundles › Duffy-binding-like domain, C-terminal subdomain › Duffy-binding-like domain, C-terminal subdomain › Duffy-binding-like domain, C-terminal subdomain | 0.59 | 46.0 | 3.82e-01 | 93.5% | 80.8% |
| 4655639 | 2003.1.2.58 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox, Pyr_redox_2 | 0.50 | 39.0 | 2.53e-01 | 95.2% | 15.9% |
D3
medium
residues 392-499
Domain cluster:
rep: ankyrin_repeat_and_PRANC_domain-containing_protein__YP_005296207__Cotia_virus_SPAn232__930275__D395-494
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4jgwA01 | 1.20.870.10 | Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 | 0.67 | 54.0 | 4.79e-01 | 86.1% | 91.0% |
| 5cl3A00 | 1.25.10.90 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › | 0.65 | 53.0 | 4.16e-01 | 88.0% | 56.7% |
| 4k6jB00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.61 | 50.0 | 3.32e-01 | 90.7% | 87.5% |
| 5dllA05 | 1.25.50.10 | Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain | 0.60 | 51.0 | 3.75e-01 | 95.4% | 87.4% |
| 1urjA03 | 1.10.150.560 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.57 | 38.0 | 4.25e-01 | 98.1% | 89.0% |
| 3d7iB00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.56 | 40.0 | 4.20e-01 | 74.1% | 100.0% |
| 4abnA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.53 | 45.0 | 3.41e-01 | 95.4% | 38.4% |
| 6hftA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.53 | 41.0 | 3.94e-01 | 88.0% | 72.4% |
| 3ecsC01 | 1.20.120.1070 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Translation initiation factor eIF-2B, N-terminal domain | 0.52 | 40.0 | 4.18e-01 | 99.1% | 89.0% |
| 4g26A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 45.0 | 3.35e-01 | 97.2% | 46.7% |
| 3vprA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 36.0 | 3.36e-01 | 75.9% | 76.6% |
| 6wv5A01 | 1.20.1440.130 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain | 0.50 | 38.0 | 3.55e-01 | 79.6% | 90.4% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3876979 | 109.4.1.293 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPP2R1A-like_HEAT | 0.70 | 56.0 | 3.33e-01 | 87.0% | 16.8% |
| 3373578 | 109.4.1.163 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SYMPK_PTA1_N | 0.68 | 59.0 | 4.94e-01 | 94.4% | 67.2% |
| 3703986 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 53.0 | 4.33e-01 | 85.2% | 75.1% |
| 3675370 | 109.4.1.209 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Katanin_con80 | 0.66 | 51.0 | 4.32e-01 | 82.4% | 68.9% |
| 3752625 | 109.4.1.682 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RasGEF_N | 0.66 | 56.0 | 5.34e-01 | 92.6% | 97.6% |
| 3994513 | 207.1.1.116 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_FBXL15 | 0.66 | 53.0 | 4.09e-01 | 87.0% | 43.9% |
| 3373161 | 109.4.1.192 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 | 0.60 | 52.0 | 4.05e-01 | 95.4% | 64.5% |
| 3648452 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 46.0 | 4.46e-01 | 87.0% | 82.4% |
| 4000197 | 109.24.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in dedicator of cytokinesis protein 9 › Helical domain in dedicator of cytokinesis protein 9 › DHR-2_Lobe_C | 0.57 | 39.0 | 3.78e-01 | 71.3% | 92.0% |
| 3954766 | 191.1.1.18 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_14 | 0.56 | 40.0 | 3.79e-01 | 75.9% | 84.2% |
| 3420694 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.56 | 45.0 | 4.28e-01 | 88.9% | 93.8% |
| 4011977 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 44.0 | 4.01e-01 | 86.1% | 71.3% |
| 4617283 | 1188.1.1.1 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Zip | 0.55 | 40.0 | 3.05e-01 | 76.9% | 42.6% |
| 3532347 | 109.4.1.209 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Katanin_con80 | 0.55 | 46.0 | 4.09e-01 | 97.2% | 63.3% |
| 3739646 | 109.4.1.192 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 | 0.54 | 46.0 | 3.36e-01 | 94.4% | 46.3% |
| 3323936 | 109.24.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in dedicator of cytokinesis protein 9 › Helical domain in dedicator of cytokinesis protein 9 › DHR-2_Lobe_C | 0.54 | 40.0 | 3.74e-01 | 77.8% | 91.1% |
| 3221474 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.54 | 39.0 | 3.14e-01 | 75.0% | 64.2% |
| 3263450 | 109.24.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in dedicator of cytokinesis protein 9 › Helical domain in dedicator of cytokinesis protein 9 › DHR-2_Lobe_C | 0.53 | 41.0 | 4.00e-01 | 82.4% | 96.7% |
| 4981019 | 109.4.1.192 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 | 0.53 | 43.0 | 3.89e-01 | 93.5% | 63.2% |
| 4952332 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.50 | 36.0 | 3.42e-01 | 75.0% | 83.8% |