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ankyrin_repeat_protein
Euk-VirPenguinpox_virus
ankyrin_repeat_protein__YP_009046008__Penguinpox_virus__648998
Identity
- Accession:
- YP_009046008 ↗
- Protein ID:
- ankyrin_repeat_protein
- Kingdom:
- euk
Quality
86.9
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Avipoxvirus›
Penguinpox_virus
TaxID: 648998
Cluster
View cluster (86 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 418-507
Domain cluster:
rep: ankyrin_repeat_and_PRANC_domain-containing_protein__YP_005296207__Cotia_virus_SPAn232__930275__D495-566
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF09372.16 best | PRANC | 37.4 | 3.60e-09 | 93.3% | 85.6% |
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3cf6E01 | 1.10.8.1240 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.84 | 35.0 | 4.95e-01 | 75.6% | 80.0% |
| 1q5nA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.69 | 47.0 | 3.47e-01 | 71.1% | 95.1% |
| 2yksA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.62 | 49.0 | 4.50e-01 | 84.4% | 86.3% |
| 2i10B02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 39.0 | 3.53e-01 | 78.9% | 46.4% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.61 | 48.0 | 4.18e-01 | 83.3% | 76.1% |
| 3rlfF04 | 1.10.3720.10 | Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like | 0.59 | 45.0 | 3.46e-01 | 85.6% | 58.1% |
| 2om6A02 | 1.10.150.400 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.58 | 35.0 | 3.77e-01 | 72.2% | 68.4% |
| 3psfA02 | 1.10.10.650 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › RuvA domain 2-like | 0.58 | 52.0 | 4.47e-01 | 100.0% | 88.9% |
| 2b5dX02 | 1.20.1430.10 | Mainly Alpha › Up-down Bundle › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase, middle domain | 0.57 | 40.0 | 3.74e-01 | 73.3% | 77.2% |
| 3fcnA00 | 1.20.1220.20 | Mainly Alpha › Up-down Bundle › Malate Synthase G; Chain: A; Domain 4 › Uncharcterised protein PF01724 | 0.57 | 47.0 | 3.92e-01 | 90.0% | 68.4% |
| 3bg2A03 | 1.10.3410.10 | Mainly Alpha › Orthogonal Bundle › putative deoxyguanosinetriphosphate triphosphohydrolase fold › putative deoxyguanosinetriphosphate triphosphohydrolase like domain | 0.57 | 40.0 | 3.99e-01 | 74.4% | 72.9% |
| 1f5qB02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.56 | 45.0 | 3.87e-01 | 85.6% | 94.9% |
| 2f2cA02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.55 | 46.0 | 4.36e-01 | 88.9% | 92.5% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.54 | 44.0 | 3.97e-01 | 85.6% | 77.3% |
| 2lfrA00 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.53 | 40.0 | 3.79e-01 | 81.1% | 85.6% |
| 3o60A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 36.0 | 2.85e-01 | 70.0% | 47.8% |
| 4hteA02 | 1.20.58.1740 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 43.0 | 4.03e-01 | 93.3% | 87.2% |
| 1lk3A00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.51 | 39.0 | 3.41e-01 | 81.1% | 95.6% |
ECOD (22)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3278820 | 191.1.1.48 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_46 | 0.85 | 48.0 | 4.29e-01 | 81.1% | 43.3% |
| 4246272 | 3921.1.1.0 ↗ | alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D | 0.75 | 58.0 | 4.58e-01 | 82.2% | 90.0% |
| 3612592 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.67 | 48.0 | 4.55e-01 | 73.3% | 77.1% |
| 5024114 | 101.1.2.652 ↗ | alpha arrays › HTH › HTH › winged helix domain › Fe_dep_repr_C | 0.66 | 57.0 | 4.96e-01 | 96.7% | 91.4% |
| 3640674 | 148.1.1.43 ↗ | alpha arrays › Histone-like › Histone-related › Histone › PF30969 | 0.66 | 48.0 | 4.38e-01 | 76.7% | 63.3% |
| 4952111 | 101.1.2.21 ↗ | alpha arrays › HTH › HTH › winged helix domain › Fe_dep_repress | 0.65 | 56.0 | 4.79e-01 | 94.4% | 82.8% |
| 5045559 | 101.1.2.652 ↗ | alpha arrays › HTH › HTH › winged helix domain › Fe_dep_repr_C | 0.64 | 56.0 | 4.81e-01 | 95.6% | 85.7% |
| 3943344 | 183.1.1.0 ↗ | alpha duplicates or obligate multimers › Iron-dependent repressor protein, dimerization domain › Iron-dependent repressor protein, dimerization domain › Iron-dependent repressor protein, dimerization domain | 0.64 | 55.0 | 4.76e-01 | 95.6% | 87.1% |
| 4982068 | 101.1.2.652 ↗ | alpha arrays › HTH › HTH › winged helix domain › Fe_dep_repr_C | 0.64 | 56.0 | 4.76e-01 | 96.7% | 85.5% |
| 3595441 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.63 | 53.0 | 4.48e-01 | 88.9% | 80.7% |
| 3415702 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.62 | 45.0 | 3.46e-01 | 77.8% | 80.9% |
| 4928573 | 183.1.1.5 ↗ | alpha duplicates or obligate multimers › Iron-dependent repressor protein, dimerization domain › Iron-dependent repressor protein, dimerization domain › Iron-dependent repressor protein, dimerization domain › Fe_dep_repress | 0.62 | 52.0 | 4.80e-01 | 93.3% | 100.0% |
| 4030602 | 10.12.1.1 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › cNMP_binding | 0.61 | 48.0 | 3.30e-01 | 84.4% | 69.4% |
| 3605109 | 101.1.10.7 ↗ | alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C | 0.60 | 52.0 | 4.24e-01 | 92.2% | 76.8% |
| 4025852 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.59 | 48.0 | 4.24e-01 | 84.4% | 85.6% |
| 3449357 | 150.1.1.110 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF7358 | 0.59 | 43.0 | 3.49e-01 | 76.7% | 55.3% |
| 4962303 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.58 | 48.0 | 3.47e-01 | 93.3% | 66.5% |
| 4501767 | 1175.1.1.1 ↗ | alpha complex topology › Apolipoprotein N-acyltransferase transmembrane domain › Apolipoprotein N-acyltransferase transmembrane domain › Apolipoprotein N-acyltransferase transmembrane domain › LNT_N | 0.56 | 39.0 | 2.95e-01 | 73.3% | 30.4% |
| 4664272 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.52 | 41.0 | 3.83e-01 | 86.7% | 73.0% |
| 3279139 | 191.1.1.35 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_35 | 0.51 | 36.0 | 3.24e-01 | 73.3% | 88.8% |
| 4886424 | 304.116.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in release factor › Ferredoxin-like domain in release factor › PCRF | 0.51 | 39.0 | 3.84e-01 | 84.4% | 86.0% |
| 3601597 | 141.1.1.0 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases | 0.51 | 39.0 | 2.83e-01 | 87.8% | 56.1% |
D2
medium
residues 1-159
Domain cluster:
rep: MN180249.1__QHJ75400.1__X__00002__D85-208
Pfam (7)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF12796.14 best | Ank_2 | 29.5 | 1.20e-06 | 49.1% | 65.6% |
| PF12796.14 | Ank_2 | 40.6 | 4.40e-10 | 41.5% | 51.1% |
| PF13637.13 | Ank_4 | 34.4 | 2.80e-08 | 30.8% | 86.0% |
| PF00023.37 | Ank | 26.9 | 5.70e-06 | 20.1% | 87.9% |
| PF13606.13 | Ank_3 | 21.9 | 2.20e-04 | 18.9% | 90.3% |
| PF00023.37 | Ank | 33.1 | 6.10e-08 | 17.0% | 78.8% |
| PF13606.13 | Ank_3 | 29.3 | 8.80e-07 | 17.0% | 87.1% |
D3
medium
residues 314-417
Domain cluster:
rep: ankyrin_repeat_protein__YP_009046157__Penguinpox_virus__648998__D421-508
CATH (21)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3keaA00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.80 | 55.0 | 3.93e-01 | 83.7% | 26.1% |
| 4epzA00 | 1.25.40.810 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ | 0.71 | 47.0 | 4.13e-01 | 79.8% | 46.1% |
| 3u4qB04 | 6.10.140.1030 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 41.0 | 4.82e-01 | 83.7% | 100.0% |
| 3wozB00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.62 | 50.0 | 3.95e-01 | 100.0% | 40.6% |
| 3fajA00 | 1.20.120.950 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein DUF5062 | 0.62 | 36.0 | 3.65e-01 | 70.2% | 57.4% |
| 7xkxA01 | 1.50.10.160 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.60 | 46.0 | 3.74e-01 | 82.7% | 44.0% |
| 3q4oA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.60 | 46.0 | 3.96e-01 | 82.7% | 92.3% |
| 4j8sA00 | 1.25.40.840 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › CCR4-NOT transcription complex subunit 1 TTP binding domain | 0.59 | 49.0 | 4.15e-01 | 91.3% | 85.6% |
| 5vjcA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.59 | 48.0 | 3.67e-01 | 90.4% | 46.9% |
| 3rc3A05 | 1.20.58.1080 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 42.0 | 4.10e-01 | 75.0% | 71.7% |
| 3pxpA02 | 3.30.450.180 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.58 | 46.0 | 3.81e-01 | 88.5% | 55.8% |
| 1udyA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.57 | 47.0 | 4.50e-01 | 90.4% | 85.8% |
| 8cdaC01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.57 | 46.0 | 4.51e-01 | 90.4% | 84.6% |
| 2or0B01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.55 | 48.0 | 4.64e-01 | 100.0% | 91.1% |
| 3lysA00 | 1.10.150.130 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain | 0.54 | 38.0 | 3.79e-01 | 73.1% | 91.4% |
| 3bqoA00 | 1.25.40.210 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain | 0.53 | 47.0 | 3.82e-01 | 100.0% | 73.3% |
| 2f07B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 45.0 | 3.70e-01 | 96.2% | 65.8% |
| 1ya0A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.51 | 43.0 | 3.58e-01 | 97.1% | 71.4% |
| 3deoA02 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.51 | 44.0 | 4.03e-01 | 100.0% | 81.5% |
| 2mabA00 | 1.10.10.1350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain | 0.50 | 36.0 | 3.58e-01 | 74.0% | 85.3% |
| 4mo7A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 37.0 | 3.41e-01 | 78.8% | 73.2% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3288697 | 223.1.1.36 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › MLTR_LBD | 0.70 | 51.0 | 4.27e-01 | 76.9% | 53.3% |
| 3699854 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 54.0 | 5.23e-01 | 85.6% | 87.0% |
| 3689952 | 226.1.1.1 ↗ | a+b two layers › POZ domain › POZ domain › POZ domain › BTB | 0.67 | 51.0 | 4.21e-01 | 100.0% | 44.7% |
| 3660543 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 52.0 | 4.51e-01 | 83.7% | 61.9% |
| 3269617 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.65 | 47.0 | 4.29e-01 | 76.0% | 91.4% |
| 3682500 | 109.4.1.31 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MA3 | 0.64 | 57.0 | 4.39e-01 | 98.1% | 56.0% |
| 3518458 | 109.4.1.43 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SAC3_GANP | 0.63 | 55.0 | 4.09e-01 | 98.1% | 73.9% |
| 3936792 | 109.4.1.1312 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30475 | 0.63 | 47.0 | 3.48e-01 | 89.4% | 30.6% |
| 4027735 | 109.4.1.31 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MA3 | 0.62 | 48.0 | 4.15e-01 | 100.0% | 52.7% |
| 3768819 | 109.4.1.43 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SAC3_GANP | 0.61 | 54.0 | 4.54e-01 | 100.0% | 88.1% |
| 3988781 | 604.6.1.63 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF3169 | 0.61 | 42.0 | 3.88e-01 | 70.2% | 77.0% |
| 3515234 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.61 | 49.0 | 4.47e-01 | 89.4% | 72.4% |
| 3657307 | 109.4.1.1310 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_TRIP12_N | 0.60 | 43.0 | 4.48e-01 | 75.0% | 80.6% |
| 3369981 | 109.4.1.1477 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT, TPR_IMB1 | 0.60 | 49.0 | 3.79e-01 | 90.4% | 81.2% |
| 3599934 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.57 | 46.0 | 4.00e-01 | 87.5% | 90.8% |
| 3226629 | 226.1.1.0 ↗ | a+b two layers › POZ domain › POZ domain › POZ domain | 0.56 | 46.0 | 4.47e-01 | 88.5% | 99.1% |
| 5014744 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.56 | 38.0 | 3.29e-01 | 71.2% | 80.6% |
| 3219228 | 101.1.1.289 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HOCHOB | 0.55 | 42.0 | 4.13e-01 | 79.8% | 80.0% |
| 5079491 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 44.0 | 3.86e-01 | 87.5% | 73.5% |
| 3399010 | 5059.1.1.5 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA | 0.54 | 40.0 | 2.85e-01 | 77.9% | 92.8% |