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ankyrin_repeat_protein
Euk-VirPenguinpox_virus
ankyrin_repeat_protein__YP_009046230__Penguinpox_virus__648998
Identity
- Accession:
- YP_009046230 ↗
- Protein ID:
- ankyrin_repeat_protein
- Kingdom:
- euk
Quality
87.2
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Avipoxvirus›
Penguinpox_virus
TaxID: 648998
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 1-55
Domain cluster:
rep: ankyrin_repeat_protein__YP_009046457__Pigeonpox_virus__10264__D1-55
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00023.37 best | Ank | 15.8 | 2.00e-02 | 41.8% | 66.7% |
D2
medium
residues 67-192
Domain cluster:
rep: MN180249.1__QHJ75400.1__X__00002__D85-208
Pfam (10)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF12796.14 best | Ank_2 | 64.5 | 1.60e-17 | 74.6% | 100.0% |
| PF12796.14 | Ank_2 | 43.9 | 3.90e-11 | 54.0% | 72.2% |
| PF13637.13 | Ank_4 | 29.7 | 8.80e-07 | 40.5% | 100.0% |
| PF13857.13 | Ank_5 | 39.8 | 6.20e-10 | 39.7% | 83.9% |
| PF13637.13 | Ank_4 | 33.3 | 6.30e-08 | 35.7% | 86.0% |
| PF00023.37 | Ank | 21.8 | 2.50e-04 | 26.2% | 90.9% |
| PF00023.37 | Ank | 39.5 | 5.50e-10 | 26.2% | 97.0% |
| PF13606.13 | Ank_3 | 31.4 | 1.80e-07 | 23.8% | 93.5% |
| PF00023.37 | Ank | 21.4 | 3.30e-04 | 21.4% | 81.8% |
| PF13606.13 | Ank_3 | 17.7 | 5.60e-03 | 21.4% | 90.3% |
D3
medium
residues 193-249
Domain cluster:
rep: ankyrin_repeat_protein__YP_009165187__Mollivirus_sibericum_Viruses.__X__D207-283
D4
medium
residues 250-355
Domain cluster:
representative
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.58 | 38.0 | 3.10e-01 | 89.6% | 35.5% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 43.0 | 3.86e-01 | 82.1% | 81.2% |
| 8himB01 | 3.90.1110.10 | Alpha Beta › Alpha-Beta Complex › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 › RNA polymerase Rpb2, domain 2 | 0.55 | 39.0 | 3.44e-01 | 71.7% | 73.5% |
| 2kjgA00 | 1.20.120.970 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.54 | 36.0 | 3.70e-01 | 93.4% | 71.7% |
| 1yuzB01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 41.0 | 3.77e-01 | 84.0% | 83.3% |
| 2r7rA03 | 1.10.10.1990 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Viral RNA-directed RNA polymerase, 4-helical domain | 0.52 | 32.0 | 3.62e-01 | 95.3% | 85.5% |
| 2es9A00 | 1.20.1290.30 | Mainly Alpha › Up-down Bundle › AhpD-like › | 0.51 | 33.0 | 3.45e-01 | 97.2% | 70.0% |
| 3fseB02 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 40.0 | 3.65e-01 | 84.9% | 78.5% |
| 3jrtA00 | 1.20.120.1060 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.50 | 41.0 | 3.59e-01 | 89.6% | 84.3% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3890108 | 3919.1.1.2 ↗ | alpha duplicates or obligate multimers › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › COMM_HN | 0.65 | 52.0 | 5.15e-01 | 99.1% | 80.9% |
| 3681 | 133.2.1.1 ↗ | alpha bundles › DH domain-like › Methenyltetrahydrofolate cyclohydrolase-like › Methenyltetrahydrofolate cyclohydrolase-like › FTCD_C | 0.58 | 38.0 | 3.10e-01 | 89.6% | 35.5% |
| 3942493 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.57 | 34.0 | 4.07e-01 | 91.5% | 86.7% |
| 3262218 | 4163.1.1.1 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 | 0.56 | 37.0 | 3.42e-01 | 97.2% | 49.7% |
| 3970612 | 3651.1.1.1 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B | 0.55 | 39.0 | 3.61e-01 | 96.2% | 56.4% |
| 4996482 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.54 | 41.0 | 3.67e-01 | 81.1% | 100.0% |
| 3637481 | 2485.1.1.0 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like | 0.51 | 41.0 | 3.22e-01 | 88.7% | 82.9% |
D5
medium
residues 356-411
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF09372.16 best | PRANC | 57.6 | 1.90e-15 | 98.2% | 52.6% |
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3hruB01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.75 | 61.0 | 4.80e-01 | 100.0% | 41.6% |
| 2odvA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 49.0 | 3.84e-01 | 71.4% | 53.6% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.68 | 44.0 | 3.99e-01 | 71.4% | 47.4% |
| 3cxbA03 | 1.10.1740.30 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain | 0.68 | 58.0 | 5.10e-01 | 94.6% | 77.8% |
| 4e4eA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.68 | 47.0 | 4.36e-01 | 76.8% | 57.7% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.67 | 49.0 | 3.48e-01 | 76.8% | 43.5% |
| 3fd9A03 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.67 | 47.0 | 4.31e-01 | 76.8% | 56.2% |
| 2db7A01 | 6.10.250.980 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.67 | 45.0 | 4.62e-01 | 76.8% | 73.6% |
| 2dgzA01 | 1.10.150.80 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › HRDC domain | 0.66 | 56.0 | 4.85e-01 | 98.2% | 85.4% |
| 1oe8A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.66 | 45.0 | 3.55e-01 | 73.2% | 39.5% |
| 1a41A02 | 1.20.120.380 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 | 0.64 | 55.0 | 4.63e-01 | 96.4% | 83.0% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 45.0 | 3.77e-01 | 75.0% | 44.3% |
| 2k85A00 | 1.10.10.440 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain | 0.63 | 43.0 | 4.10e-01 | 75.0% | 61.5% |
| 2lwxA00 | 1.10.8.840 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ribosome-associated complex head domain | 0.62 | 51.0 | 4.55e-01 | 100.0% | 65.9% |
| 3ilkA02 | 1.10.8.590 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.62 | 50.0 | 4.78e-01 | 94.6% | 82.4% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.62 | 54.0 | 4.70e-01 | 100.0% | 86.2% |
| 3qygB01 | 1.10.472.20 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Nitrile hydratase, beta subunit | 0.62 | 44.0 | 3.51e-01 | 89.3% | 36.4% |
| 4fwvA02 | 1.20.120.1680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.61 | 48.0 | 3.70e-01 | 87.5% | 38.1% |
| 2a19A02 | 1.10.150.190 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Translation initiation factor 2; subunit 1; domain 2 | 0.60 | 54.0 | 4.67e-01 | 100.0% | 94.1% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.58 | 43.0 | 4.13e-01 | 80.4% | 78.1% |
| 2fzlA02 | 6.10.140.1180 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 42.0 | 4.06e-01 | 76.8% | 88.7% |
| 2a3qA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.56 | 40.0 | 3.27e-01 | 76.8% | 42.5% |
| 2dofA00 | 1.10.10.440 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain | 0.55 | 43.0 | 3.71e-01 | 91.1% | 55.3% |
| 3pe0A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 47.0 | 3.75e-01 | 100.0% | 84.0% |
| 2x48A00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.50 | 35.0 | 3.63e-01 | 73.2% | 79.6% |
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3963070 | 604.1.1.263 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF3375 | 0.71 | 48.0 | 3.61e-01 | 71.4% | 40.0% |
| 3673314 | 109.4.1.106 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CPL | 0.70 | 48.0 | 2.73e-01 | 71.4% | 7.7% |
| 3698292 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.70 | 48.0 | 3.55e-01 | 73.2% | 35.2% |
| 4934319 | 101.1.2.947 ↗ | alpha arrays › HTH › HTH › winged helix domain › PF27234 | 0.70 | 51.0 | 4.88e-01 | 82.1% | 68.3% |
| 3282443 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.69 | 44.0 | 3.76e-01 | 71.4% | 40.0% |
| 3512559 | 192.1.1.37 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › DUF7753 | 0.68 | 52.0 | 4.99e-01 | 83.9% | 76.9% |
| 3251599 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.67 | 45.0 | 4.13e-01 | 78.6% | 52.0% |
| 3701737 | 103.1.1.0 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain | 0.67 | 52.0 | 4.86e-01 | 89.3% | 68.6% |
| 1068675 | 3714.1.1.0 ↗ | a+b two layers › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain | 0.63 | 49.0 | 3.48e-01 | 83.9% | 30.1% |
| 3229793 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.63 | 50.0 | 4.33e-01 | 85.7% | 58.8% |
| 3566658 | 2006.1.4.33 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › Tim17 | 0.63 | 48.0 | 4.37e-01 | 85.7% | 62.7% |
| 3687276 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.62 | 49.0 | 4.27e-01 | 85.7% | 100.0% |
| 3395688 | 3745.1.1.1 ↗ | alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex | 0.62 | 52.0 | 3.17e-01 | 96.4% | 57.1% |
| 3971395 | 101.1.1.42 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2 | 0.62 | 46.0 | 4.12e-01 | 78.6% | 94.7% |
| 3430243 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.61 | 55.0 | 4.90e-01 | 100.0% | 77.5% |
| 5060253 | 632.23.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Helical linker domain in nicking endonuclease N.BspD6I › Helical linker domain in nicking endonuclease N.BspD6I | 0.61 | 55.0 | 5.24e-01 | 100.0% | 100.0% |
| 3341256 | 109.3.1.137 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF3490 | 0.59 | 49.0 | 4.85e-01 | 96.4% | 88.3% |
| 3412847 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.58 | 40.0 | 4.11e-01 | 76.8% | 82.0% |
| 4941976 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.58 | 52.0 | 4.15e-01 | 100.0% | 59.1% |
| 3592748 | 102.1.1.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like | 0.58 | 40.0 | 3.99e-01 | 80.4% | 68.3% |
| 4951651 | 5042.1.1.1 ↗ | extended segments › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › CorA | 0.57 | 42.0 | 3.98e-01 | 82.1% | 69.1% |
| 2703757 | 4984.1.1.0 ↗ | alpha bundles › Duffy-binding-like domain, C-terminal subdomain › Duffy-binding-like domain, C-terminal subdomain › Duffy-binding-like domain, C-terminal subdomain | 0.56 | 47.0 | 3.36e-01 | 96.4% | 70.3% |
| 3643932 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.56 | 41.0 | 3.60e-01 | 78.6% | 62.4% |
| 3310956 | 630.1.1.0 ↗ | a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain | 0.56 | 42.0 | 3.05e-01 | 80.4% | 38.9% |
| 5018159 | 101.29.1.1 ↗ | alpha arrays › HTH › helical bundles in heme iron utilization protein-like › helical bundles in heme iron utilization protein-like › DUF790 | 0.56 | 36.0 | 3.78e-01 | 85.7% | 74.0% |
| 4947367 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.52 | 47.0 | 3.58e-01 | 100.0% | 74.4% |
| 3266463 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.51 | 34.0 | 3.49e-01 | 75.0% | 70.9% |