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antigenic_virion_protein

Euk-Vir

Human_betaherpesvirus_6B

antigenic_virion_protein__NP_050192__Human_betaherpesvirus_6B__32604

Identity

Accession:: NP_050192 ↗
Protein ID:: antigenic_virion_protein
Kingdom:: euk

Quality

49.1 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Roseolovirus› Human_betaherpesvirus_6B

TaxID: 32604

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 81-204

PDB

Domain cluster: rep: GP32__YP_007417806__Caviid_betaherpesvirus_2__33706__D75-212

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF06070.16 best	Herpes_UL32	192.3	1.60e-56	100.0%	12.5%

CATH (8)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3pmiA02	6.10.300.20	Special › Helix non-globular › cAMP-dependent Protein Kinase, Chain A ›	0.63	27.0	4.03e-01	98.4%	100.0%
3d85C00	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.57	42.0	4.11e-01	98.4%	71.4%
1b5lA00	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.55	40.0	3.79e-01	100.0%	62.5%
7cfmR01	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.53	45.0	3.56e-01	93.5%	99.6%
1orsC00	1.20.120.350	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C	0.52	32.0	3.21e-01	81.5%	58.3%
3caxA01	1.20.120.520	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like	0.52	43.0	3.53e-01	87.9%	60.4%
1wvtA00	1.20.1200.10	Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like	0.51	42.0	3.96e-01	100.0%	74.3%
2hszA02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.50	29.0	3.51e-01	96.8%	90.7%

ECOD (18)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3499672	1203.1.2.13 ↗	alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › Ribophorin_II	0.60	42.0	3.93e-01	71.8%	88.0%
3782769	3352.1.1.4 ↗	alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › Alg6_Alg8	0.58	53.0	3.44e-01	99.2%	84.5%
3651030	633.4.1.1 ↗	alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI	0.55	51.0	4.51e-01	100.0%	91.4%
3212065	174.1.1.0 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain	0.55	45.0	4.38e-01	100.0%	80.7%
4989256	5067.1.1.4 ↗	alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL	0.55	49.0	3.57e-01	100.0%	96.3%
3207635	174.1.1.0 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain	0.54	50.0	4.59e-01	100.0%	83.7%
3792376	193.1.1.18 ↗	alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like › DUF2465	0.54	44.0	4.41e-01	88.7%	93.8%
4019886	633.10.1.0 ↗	alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like	0.54	48.0	4.68e-01	100.0%	88.1%
3571379	193.1.1.18 ↗	alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like › DUF2465	0.54	39.0	3.98e-01	88.7%	76.0%
3868848	601.1.2.47 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › MARVEL	0.53	50.0	4.91e-01	100.0%	96.2%
3257437	193.1.1.1 ↗	alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like › CH	0.53	43.0	4.11e-01	87.1%	94.5%
5033626	5067.1.1.4 ↗	alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL	0.53	46.0	3.90e-01	98.4%	91.8%
3901994	633.23.1.22 ↗	alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL	0.53	49.0	4.89e-01	100.0%	95.4%
4511746	150.5.1.51 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100_2	0.53	28.0	2.48e-01	71.0%	36.0%
5040221	206.1.2.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › SAICAR_synt	0.53	41.0	3.20e-01	85.5%	95.0%
3722987	5050.1.1.1 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr	0.52	37.0	3.15e-01	72.6%	53.3%
3189342	5050.1.1.9 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1	0.52	37.0	3.09e-01	72.6%	48.4%
4525096	633.4.1.1 ↗	alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI	0.51	45.0	4.14e-01	100.0%	73.3%

D2 medium residues 15-77_229-282

PDB

Domain cluster: rep: Tegument_protein_of_HCMV__YP_214046__Murid_betaherpesvirus_1__10366__D20-88_233-298

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF06070.16 best	Herpes_UL32	98.2	4.30e-28	54.7%	5.7%
PF06070.16	Herpes_UL32	59.8	1.60e-16	47.0%	5.6%

CATH (7)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3rfyA02	1.20.120.290	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle	0.58	40.0	4.13e-01	70.1%	99.1%
2m6uA00	1.20.81.20	Mainly Alpha › Up-down Bundle › Receptor-associated Protein ›	0.58	30.0	3.54e-01	70.1%	70.7%
4gycA00	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.52	47.0	3.82e-01	100.0%	63.6%
3a7kB00	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.52	46.0	3.61e-01	100.0%	55.0%
7zcvA02	1.25.40.400	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.51	41.0	3.41e-01	85.5%	92.9%
3ihvA03	1.25.40.900	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.51	42.0	3.99e-01	88.9%	74.8%
3rrcB01	1.20.1310.20	Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Duffy-antigen binding domain	0.50	37.0	3.37e-01	77.8%	68.4%

ECOD (5)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3780808	174.1.1.1 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin	0.59	36.0	3.66e-01	88.0%	60.2%
5029310	3352.1.1.0 ↗	alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain	0.54	48.0	3.20e-01	97.4%	53.4%
3600606	310.2.1.0 ↗	a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF	0.51	44.0	3.87e-01	94.0%	84.6%
3830164	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.50	41.0	3.17e-01	86.3%	85.5%
3695102	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.50	44.0	2.99e-01	96.6%	39.1%