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aot2015-NO08_SRR1761682_USA_scaffold_2_curated_prodigal-single.1__X__X__00201
Bact-Viraot2015-NO08_SRR1761682_USA_scaffold_2_curated_prodigal-single.1__X__X__00201
Identity
- Kingdom:
- phage
Quality
87.6
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 248-262_297-372
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00078.33 best | RVT_1 | 42.9 | 7.40e-11 | 84.6% | 37.0% |
CATH (16)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7uinD01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.94 | 82.0 | 6.50e-01 | 96.7% | 49.7% |
| 2iboA00 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.69 | 52.0 | 5.32e-01 | 98.9% | 82.0% |
| 1i72A00 | 3.60.90.10 | Alpha Beta › 4-Layer Sandwich › S-adenosylmethionine decarboxylase › S-adenosylmethionine decarboxylase | 0.68 | 52.0 | 3.77e-01 | 81.3% | 84.5% |
| 1vk8A00 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.65 | 48.0 | 4.85e-01 | 98.9% | 78.5% |
| 7npaA02 | 3.30.70.3340 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 39.0 | 4.00e-01 | 76.9% | 67.1% |
| 7r7eA01 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.60 | 48.0 | 4.39e-01 | 86.8% | 94.1% |
| 5mghA01 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.60 | 51.0 | 3.54e-01 | 94.5% | 73.6% |
| 2v8qB00 | 6.20.250.60 | Special › Other non-globular › Double Stranded RNA Binding Domain › | 0.55 | 27.0 | 3.05e-01 | 81.3% | 58.9% |
| 2i8eA01 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 37.0 | 3.98e-01 | 76.9% | 86.5% |
| 1d5aA01 | 3.30.342.10 | Alpha Beta › 2-Layer Sandwich › DNA Polymerase; Chain A, domain 1 › DNA Polymerase, chain B, domain 1 | 0.54 | 48.0 | 4.07e-01 | 100.0% | 69.5% |
| 3nm6B00 | 3.40.50.1580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain | 0.53 | 47.0 | 3.57e-01 | 100.0% | 87.3% |
| 2co5A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 30.0 | 3.08e-01 | 85.7% | 54.3% |
| 1z2aA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.53 | 40.0 | 3.39e-01 | 82.4% | 93.3% |
| 2f1rA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.51 | 37.0 | 3.14e-01 | 74.7% | 76.4% |
| 3eb8B01 | 3.10.450.460 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › EspG protein, N-terminal domain | 0.51 | 29.0 | 3.45e-01 | 95.6% | 83.6% |
| 4wfvA00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.51 | 42.0 | 3.57e-01 | 94.5% | 54.9% |
ECOD (39)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3989356 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.94 | 83.0 | 6.33e-01 | 100.0% | 45.4% |
| 4461237 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.93 | 89.0 | 5.32e-01 | 100.0% | 34.0% |
| 3645796 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.93 | 76.0 | 5.10e-01 | 85.7% | 33.0% |
| 1827765 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.91 | 83.0 | 5.57e-01 | 100.0% | 29.6% |
| 3834374 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.91 | 86.0 | 5.41e-01 | 100.0% | 23.7% |
| 3304359 | 304.48.1.70 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Intron_maturas2 | 0.90 | 85.0 | 5.15e-01 | 100.0% | 26.7% |
| 4241274 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.87 | 81.0 | 5.10e-01 | 100.0% | 28.2% |
| 4088089 | 304.48.1.39 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N | 0.87 | 81.0 | 5.44e-01 | 100.0% | 36.5% |
| 4544858 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.87 | 81.0 | 5.03e-01 | 100.0% | 33.8% |
| 3679386 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.87 | 82.0 | 5.32e-01 | 100.0% | 28.9% |
| 4486052 | 304.48.1.39 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N | 0.87 | 81.0 | 5.32e-01 | 100.0% | 43.5% |
| 4449545 | 304.48.1.39 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N | 0.87 | 81.0 | 5.25e-01 | 100.0% | 43.4% |
| 4037822 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.86 | 80.0 | 5.02e-01 | 100.0% | 35.2% |
| 4635290 | 4967.1.1.25 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N | 0.86 | 79.0 | 4.99e-01 | 100.0% | 30.9% |
| 4223395 | 4967.1.1.25 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N | 0.86 | 79.0 | 5.04e-01 | 100.0% | 28.0% |
| 4442725 | 4967.1.1.25 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N | 0.86 | 79.0 | 4.93e-01 | 100.0% | 33.7% |
| 4361292 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.86 | 79.0 | 4.90e-01 | 100.0% | 32.6% |
| 4126255 | 4967.1.1.25 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N | 0.84 | 77.0 | 5.36e-01 | 100.0% | 43.6% |
| 3935908 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.83 | 69.0 | 6.16e-01 | 100.0% | 64.8% |
| 4543273 | 304.36.1.1 ↗ | a+b two layers › Alpha-beta plaits › YajQ-like › YajQ-like › DUF520 | 0.82 | 54.0 | 6.23e-01 | 70.3% | 93.8% |
| 4598960 | 304.36.1.0 ↗ | a+b two layers › Alpha-beta plaits › YajQ-like › YajQ-like | 0.80 | 53.0 | 5.95e-01 | 71.4% | 88.6% |
| 4391867 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.79 | 72.0 | 4.56e-01 | 100.0% | 33.5% |
| 3513420 | 391.1.1.0 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module | 0.69 | 28.0 | 3.99e-01 | 80.2% | 82.5% |
| 4523246 | 391.1.2.3 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › VWC domain-related › SVWC | 0.68 | 28.0 | 3.35e-01 | 80.2% | 53.8% |
| 3646906 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.65 | 45.0 | 4.45e-01 | 74.7% | 68.4% |
| 4369033 | 391.1.2.0 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › VWC domain-related | 0.65 | 30.0 | 3.01e-01 | 81.3% | 40.0% |
| 1699894 | 304.48.2.2 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › 'palm' domain in birnaviruse RNA-dependent RNA polymerase › Permu_RdRp_palm | 0.62 | 54.0 | 3.39e-01 | 97.8% | 68.1% |
| 3980816 | 3261.1.1.0 ↗ | a+b two layers › amino-terminal domain of OmpATb › amino-terminal domain of OmpATb › amino-terminal domain of OmpATb | 0.61 | 43.0 | 4.60e-01 | 95.6% | 89.3% |
| 3508453 | 391.1.1.0 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module | 0.61 | 26.0 | 3.67e-01 | 71.4% | 97.1% |
| 3573819 | 391.1.1.0 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module | 0.60 | 28.0 | 3.55e-01 | 81.3% | 75.5% |
| 3998976 | 391.1.1.0 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module | 0.60 | 26.0 | 3.46e-01 | 80.2% | 77.8% |
| 3224321 | 391.1.1.0 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module | 0.59 | 24.0 | 3.44e-01 | 79.1% | 88.6% |
| 3212142 | 391.1.1.0 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module | 0.58 | 26.0 | 3.46e-01 | 79.1% | 97.1% |
| 3231088 | 391.1.1.0 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module | 0.57 | 27.0 | 3.53e-01 | 81.3% | 92.5% |
| 3584990 | 391.1.1.0 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module | 0.56 | 26.0 | 3.31e-01 | 81.3% | 79.5% |
| 3624010 | 391.1.1.0 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module | 0.55 | 25.0 | 3.07e-01 | 80.2% | 66.0% |
| 3279969 | 2008.1.1.20 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Uma2 | 0.53 | 43.0 | 3.46e-01 | 90.1% | 93.7% |
| 3666379 | 2004.1.1.548 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras, Roc | 0.52 | 39.0 | 3.06e-01 | 82.4% | 93.0% |
| 3399130 | 7524.1.1.4 ↗ | a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › DUF1487 | 0.52 | 39.0 | 3.04e-01 | 84.6% | 69.1% |
D2
high
residues 374-479
Domain cluster:
representative
CATH (40)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3kfwX03 | 1.20.58.1460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 45.0 | 5.25e-01 | 95.3% | 89.5% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 44.0 | 4.90e-01 | 98.1% | 80.0% |
| 2m6bA00 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.69 | 48.0 | 4.33e-01 | 72.6% | 56.0% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.69 | 45.0 | 5.18e-01 | 97.2% | 93.3% |
| 3pvuA02 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.68 | 43.0 | 4.96e-01 | 95.3% | 85.0% |
| 2chnB03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.67 | 53.0 | 4.44e-01 | 100.0% | 50.0% |
| 8jpdG01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.64 | 43.0 | 3.84e-01 | 99.1% | 49.7% |
| 4g10A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.64 | 53.0 | 4.90e-01 | 90.6% | 69.9% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.64 | 41.0 | 4.70e-01 | 95.3% | 88.3% |
| 2nq2A00 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.63 | 52.0 | 3.77e-01 | 89.6% | 50.0% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.63 | 40.0 | 4.69e-01 | 95.3% | 93.2% |
| 4jgiA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.62 | 40.0 | 4.45e-01 | 90.6% | 85.0% |
| 1y6xA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.62 | 35.0 | 3.84e-01 | 90.6% | 65.5% |
| 2jpnA00 | 1.20.1280.210 | Mainly Alpha › Up-down Bundle › Monooxygenase › Uncharacterised protein UvsW.1 | 0.62 | 39.0 | 4.36e-01 | 96.2% | 83.5% |
| 1zvzA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 46.0 | 4.35e-01 | 98.1% | 66.1% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 53.0 | 4.36e-01 | 93.4% | 81.1% |
| 4dlqA02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.61 | 43.0 | 4.58e-01 | 91.5% | 82.1% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.60 | 43.0 | 4.13e-01 | 73.6% | 81.0% |
| 1vmgA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.60 | 35.0 | 3.86e-01 | 91.5% | 72.0% |
| 3nyjA00 | 1.20.120.770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain | 0.60 | 50.0 | 4.09e-01 | 98.1% | 51.4% |
| 2xqyA01 | 3.30.500.50 | Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › | 0.59 | 44.0 | 3.74e-01 | 87.7% | 47.2% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 50.0 | 4.20e-01 | 95.3% | 57.0% |
| 3rkoG00 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 39.0 | 4.01e-01 | 98.1% | 73.0% |
| 1txuA02 | 1.20.1050.80 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › VPS9 domain | 0.57 | 49.0 | 4.32e-01 | 94.3% | 63.1% |
| 4fymF00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.57 | 51.0 | 4.08e-01 | 98.1% | 93.3% |
| 7powA01 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.57 | 50.0 | 4.15e-01 | 99.1% | 90.9% |
| 1z5zA02 | 1.20.120.850 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SWI2/SNF2 ATPases, N-terminal domain | 0.57 | 36.0 | 4.22e-01 | 93.4% | 90.8% |
| 2l1lB00 | 1.20.1440.250 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.57 | 48.0 | 4.57e-01 | 91.5% | 85.0% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.57 | 49.0 | 4.51e-01 | 100.0% | 72.9% |
| 2y1vA04 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.56 | 48.0 | 4.00e-01 | 93.4% | 73.0% |
| 7eu3E01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 38.0 | 4.20e-01 | 98.1% | 86.2% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.56 | 47.0 | 4.62e-01 | 100.0% | 85.0% |
| 2wzkA01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.56 | 46.0 | 4.37e-01 | 91.5% | 90.6% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.55 | 48.0 | 4.43e-01 | 100.0% | 74.0% |
| 1vljA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.55 | 48.0 | 3.83e-01 | 94.3% | 67.8% |
| 6a7hA01 | 1.20.140.180 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.54 | 44.0 | 4.14e-01 | 96.2% | 70.5% |
| 2yxhA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.54 | 34.0 | 3.36e-01 | 91.5% | 57.5% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.54 | 43.0 | 4.47e-01 | 98.1% | 93.9% |
| 2hydA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.53 | 44.0 | 3.17e-01 | 91.5% | 89.5% |
| 1xioA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 47.0 | 3.75e-01 | 100.0% | 76.5% |
ECOD (49)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3587125 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.91 | 88.0 | 7.42e-01 | 100.0% | 68.8% |
| 3738358 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.73 | 48.0 | 5.54e-01 | 94.3% | 93.3% |
| 4001318 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.73 | 50.0 | 5.92e-01 | 93.4% | 100.0% |
| 4181805 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.72 | 44.0 | 5.09e-01 | 97.2% | 83.3% |
| 4474310 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.71 | 45.0 | 5.13e-01 | 97.2% | 85.0% |
| 4270503 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.71 | 45.0 | 4.99e-01 | 97.2% | 80.0% |
| 4290271 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.70 | 44.0 | 4.80e-01 | 97.2% | 75.6% |
| 165995 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.69 | 45.0 | 5.18e-01 | 97.2% | 93.3% |
| 3669330 | 604.1.1.148 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TBCC_N | 0.68 | 49.0 | 5.44e-01 | 97.2% | 94.1% |
| 3498352 | 109.4.1.509 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RRP12_HEAT | 0.67 | 57.0 | 3.30e-01 | 90.6% | 18.9% |
| 4321884 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.67 | 43.0 | 4.62e-01 | 98.1% | 74.2% |
| 5012498 | 3843.1.1.28 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MbhD | 0.66 | 39.0 | 4.97e-01 | 95.3% | 96.9% |
| 4063100 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.66 | 42.0 | 4.77e-01 | 97.2% | 85.0% |
| 3596737 | 604.8.1.0 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo | 0.66 | 48.0 | 4.47e-01 | 75.5% | 78.5% |
| 3234201 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.66 | 47.0 | 4.45e-01 | 73.6% | 79.2% |
| 4577904 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.65 | 43.0 | 4.79e-01 | 98.1% | 87.5% |
| 5038239 | 3843.1.1.31 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q3 | 0.65 | 40.0 | 4.62e-01 | 96.2% | 85.3% |
| 3973009 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.65 | 46.0 | 3.92e-01 | 72.6% | 90.0% |
| 3488877 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.64 | 54.0 | 4.00e-01 | 90.6% | 75.9% |
| 3520954 | 109.4.1.162 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nup192 | 0.63 | 52.0 | 2.92e-01 | 91.5% | 10.2% |
| 3971927 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.63 | 42.0 | 4.73e-01 | 98.1% | 86.9% |
| 4578841 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.62 | 49.0 | 5.27e-01 | 97.2% | 98.9% |
| 4498502 | 3843.1.1.6 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MrpF_PhaF | 0.62 | 43.0 | 4.54e-01 | 98.1% | 78.9% |
| 4029372 | 109.4.1.528 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CBF | 0.62 | 52.0 | 3.61e-01 | 92.5% | 33.0% |
| 4024521 | 109.25.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A | 0.62 | 50.0 | 5.26e-01 | 89.6% | 96.8% |
| 3507345 | 109.4.1.828 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Htt_C-HEAT | 0.61 | 52.0 | 3.96e-01 | 94.3% | 45.9% |
| 3704699 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.61 | 49.0 | 5.15e-01 | 97.2% | 95.8% |
| 3605145 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.60 | 53.0 | 4.06e-01 | 98.1% | 88.0% |
| 3475220 | 109.54.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 | 0.60 | 52.0 | 4.33e-01 | 94.3% | 70.3% |
| 4930533 | 3843.1.1.6 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MrpF_PhaF | 0.60 | 43.0 | 4.87e-01 | 98.1% | 96.2% |
| 4325839 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.59 | 38.0 | 4.45e-01 | 96.2% | 98.6% |
| 4932209 | 3843.1.1.6 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MrpF_PhaF | 0.59 | 40.0 | 4.49e-01 | 98.1% | 91.3% |
| 3937037 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 48.0 | 3.99e-01 | 91.5% | 59.5% |
| 4167544 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.58 | 40.0 | 4.12e-01 | 70.8% | 80.0% |
| 3478399 | 604.8.1.0 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo | 0.58 | 49.0 | 3.83e-01 | 92.5% | 90.0% |
| 3222099 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 48.0 | 4.25e-01 | 90.6% | 67.1% |
| 5023802 | 3843.1.1.2 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DUF2108 | 0.58 | 34.0 | 4.10e-01 | 95.3% | 88.6% |
| 4143595 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.58 | 40.0 | 4.19e-01 | 71.7% | 85.3% |
| 3603229 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.57 | 38.0 | 4.21e-01 | 98.1% | 84.7% |
| 3720663 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.56 | 51.0 | 3.37e-01 | 100.0% | 72.9% |
| 4088690 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.55 | 36.0 | 3.98e-01 | 97.2% | 85.0% |
| 5041261 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.54 | 48.0 | 4.43e-01 | 98.1% | 74.8% |
| 3749753 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 46.0 | 2.94e-01 | 91.5% | 21.6% |
| 4000086 | 5.1.5.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed | 0.54 | 47.0 | 2.82e-01 | 99.1% | 84.8% |
| 3509109 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.53 | 47.0 | 4.59e-01 | 100.0% | 89.6% |
| 5023803 | 3843.1.1.36 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DUF2107 | 0.51 | 35.0 | 3.73e-01 | 98.1% | 81.1% |
| 3694135 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.51 | 43.0 | 3.15e-01 | 93.4% | 44.9% |
| 3823586 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 43.0 | 3.72e-01 | 93.4% | 60.0% |
| 3260122 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.50 | 46.0 | 3.61e-01 | 100.0% | 71.8% |
D3
high
residues 516-623
Domain cluster:
rep: rifcsphigho2-12_scaffold_combined_curated_prodigal-single.1__X__X__00233__D118-220
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01844.30 best | HNH | 29.8 | 7.60e-07 | 50.0% | 74.5% |
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2qgpA00 | 1.10.30.50 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › | 0.71 | 50.0 | 5.69e-01 | 74.1% | 95.2% |
| 3m7kA00 | 3.30.40.220 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › | 0.64 | 52.0 | 4.74e-01 | 87.0% | 87.3% |
| 2x5rA01 | 3.30.470.40 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › | 0.53 | 36.0 | 3.61e-01 | 70.4% | 91.3% |
ECOD (47)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3590055 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.98 | 94.0 | 9.17e-01 | 99.1% | 93.9% |
| 3587782 | 378.1.1.0 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases | 0.97 | 92.0 | 9.14e-01 | 97.2% | 95.5% |
| 5049537 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.88 | 51.0 | 5.49e-01 | 88.0% | 67.0% |
| 4959591 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.85 | 51.0 | 6.53e-01 | 83.3% | 100.0% |
| 4932123 | 377.7.1.2 ↗ | few secondary structure elements › Glucocorticoid receptor-like › 82 prophage-derived uncharacterized protein ybcO › 82 prophage-derived uncharacterized protein ybcO › HNH | 0.84 | 51.0 | 6.36e-01 | 79.6% | 95.7% |
| 3952776 | 377.1.1.88 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › HNH | 0.84 | 50.0 | 6.40e-01 | 81.5% | 100.0% |
| 4951302 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.80 | 47.0 | 5.88e-01 | 79.6% | 96.9% |
| 3277754 | 377.1.1.88 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › HNH | 0.78 | 46.0 | 5.63e-01 | 80.6% | 91.4% |
| 3952818 | 378.1.1.27 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_5 | 0.77 | 46.0 | 5.48e-01 | 80.6% | 86.5% |
| 3950953 | 377.1.1.78 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › HNH_5 | 0.77 | 45.0 | 5.60e-01 | 80.6% | 91.4% |
| 5070853 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.75 | 51.0 | 5.74e-01 | 83.3% | 88.2% |
| 5039655 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.75 | 52.0 | 6.04e-01 | 87.0% | 96.2% |
| 2485694 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.74 | 55.0 | 5.04e-01 | 88.0% | 61.2% |
| 5080086 | 378.1.1.0 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases | 0.74 | 49.0 | 5.58e-01 | 86.1% | 90.0% |
| 4966182 | 378.1.1.9 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_2 | 0.74 | 58.0 | 5.51e-01 | 82.4% | 93.6% |
| 3948700 | 378.1.1.9 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_2 | 0.73 | 58.0 | 5.51e-01 | 83.3% | 97.6% |
| 4998487 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.73 | 50.0 | 5.36e-01 | 87.0% | 80.0% |
| 4999440 | 378.1.1.27 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_5 | 0.72 | 50.0 | 5.64e-01 | 92.6% | 90.6% |
| 4981807 | 378.1.1.9 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_2 | 0.71 | 58.0 | 5.11e-01 | 87.0% | 79.4% |
| 185780 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.69 | 51.0 | 5.38e-01 | 75.9% | 84.5% |
| 4941657 | 377.1.1.88 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › HNH | 0.69 | 45.0 | 5.36e-01 | 76.9% | 96.0% |
| 3981149 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.69 | 48.0 | 5.56e-01 | 88.0% | 97.5% |
| 3307439 | 378.1.1.0 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases | 0.68 | 49.0 | 4.67e-01 | 73.1% | 78.7% |
| 5019258 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.67 | 47.0 | 5.38e-01 | 83.3% | 97.5% |
| 3440476 | 378.1.1.10 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_4 | 0.65 | 51.0 | 4.90e-01 | 81.5% | 73.1% |
| 3952384 | 378.1.1.0 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases | 0.65 | 50.0 | 5.36e-01 | 80.6% | 95.8% |
| 3317146 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.64 | 51.0 | 4.83e-01 | 82.4% | 73.4% |
| 3952923 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.63 | 49.0 | 5.09e-01 | 80.6% | 90.0% |
| 5082962 | 378.1.1.0 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases | 0.63 | 49.0 | 4.96e-01 | 85.2% | 80.0% |
| 3953059 | 378.1.1.0 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases | 0.63 | 49.0 | 5.34e-01 | 81.5% | 100.0% |
| 3952892 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.62 | 53.0 | 5.04e-01 | 89.8% | 80.8% |
| 8235 | 378.1.1.3 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › Endonuclease_7 | 0.59 | 46.0 | 4.73e-01 | 82.4% | 84.5% |
| 5016552 | 378.1.1.10 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_4 | 0.59 | 49.0 | 4.91e-01 | 87.0% | 99.1% |
| 1144783 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.59 | 54.0 | 4.72e-01 | 100.0% | 81.2% |
| 4943720 | 378.1.1.0 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases | 0.58 | 47.0 | 4.51e-01 | 85.2% | 99.2% |
| 3953524 | 378.1.1.23 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › DUF222 | 0.58 | 52.0 | 4.54e-01 | 95.4% | 89.0% |
| 3953218 | 378.1.1.23 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › DUF222 | 0.57 | 52.0 | 4.53e-01 | 95.4% | 87.1% |
| 2449258 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.57 | 53.0 | 4.54e-01 | 100.0% | 76.2% |
| 4989310 | 378.1.1.27 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_5 | 0.57 | 41.0 | 3.35e-01 | 74.1% | 68.8% |
| 2991844 | 378.1.1.10 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_4 | 0.56 | 50.0 | 5.01e-01 | 95.4% | 100.0% |
| 4986026 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.56 | 41.0 | 3.37e-01 | 75.0% | 70.3% |
| 3602299 | 378.1.1.0 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases | 0.56 | 46.0 | 4.14e-01 | 88.9% | 89.3% |
| 4839754 | 378.1.1.2 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH | 0.56 | 51.0 | 4.54e-01 | 100.0% | 84.9% |
| 4187709 | 378.1.1.0 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases | 0.55 | 51.0 | 3.37e-01 | 100.0% | 50.0% |
| 3957069 | 378.1.1.0 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases | 0.55 | 51.0 | 4.42e-01 | 100.0% | 80.0% |
| 4110524 | 4979.2.1.1 ↗ | alpha arrays › C-terminal domain of Hypothetical protein MPN330-like › XRN2-binding domain (XTBD) › XRN2-binding domain (XTBD) › XTBD | 0.52 | 37.0 | 3.88e-01 | 99.1% | 83.2% |
| 3590662 | 377.4.1.1 ↗ | few secondary structure elements › Glucocorticoid receptor-like › YlxR-like › YlxR-like › YlxR | 0.51 | 33.0 | 3.61e-01 | 98.1% | 80.0% |
D4
medium
residues 43-148
Domain cluster:
representative
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2vfkA00 | 3.90.1140.10 | Alpha Beta › Alpha-Beta Complex › Cyclic Phosphodiesterase; Chain: A, › Cyclic phosphodiesterase | 0.63 | 37.0 | 3.00e-01 | 100.0% | 29.8% |
| 3im8A02 | 3.30.70.250 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding | 0.58 | 31.0 | 3.60e-01 | 87.7% | 72.6% |
| 2cteA01 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.55 | 36.0 | 4.02e-01 | 86.8% | 87.3% |
| 4pk9A00 | 3.40.1090.10 | Alpha Beta › 3-Layer(aba) Sandwich › Cytosolic phospholipase A2 catalytic domain › Cytosolic phospholipase A2 catalytic domain | 0.51 | 43.0 | 3.04e-01 | 94.3% | 93.3% |
| 6b4rA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.51 | 42.0 | 3.21e-01 | 92.5% | 53.9% |
| 4qjvB00 | 3.30.1360.10 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit | 0.50 | 33.0 | 3.45e-01 | 90.6% | 74.5% |
ECOD (37)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3589612 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 1.00 | 98.0 | 6.50e-01 | 100.0% | 33.3% |
| 4004424 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.94 | 91.0 | 5.91e-01 | 100.0% | 28.5% |
| 5002351 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.92 | 88.0 | 5.76e-01 | 100.0% | 28.3% |
| 4516798 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.92 | 87.0 | 5.47e-01 | 100.0% | 23.1% |
| 4071235 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.91 | 87.0 | 5.36e-01 | 100.0% | 20.8% |
| 3173834 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.91 | 86.0 | 5.51e-01 | 100.0% | 25.4% |
| 4461237 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.91 | 85.0 | 5.23e-01 | 100.0% | 20.2% |
| 3945039 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.91 | 84.0 | 5.71e-01 | 100.0% | 31.2% |
| 5018583 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.89 | 83.0 | 5.69e-01 | 100.0% | 32.7% |
| 3954143 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.89 | 67.0 | 5.54e-01 | 78.3% | 50.9% |
| 5029718 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.89 | 78.0 | 5.23e-01 | 98.1% | 28.5% |
| 5018572 | 304.48.1.72 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_N | 0.88 | 81.0 | 6.63e-01 | 100.0% | 57.2% |
| 4497954 | 304.48.1.73 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1, RVT_N | 0.88 | 83.0 | 5.74e-01 | 100.0% | 34.8% |
| 4872037 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.87 | 78.0 | 5.61e-01 | 100.0% | 37.2% |
| 4937067 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.86 | 75.0 | 5.45e-01 | 100.0% | 37.0% |
| 1827765 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.85 | 80.0 | 5.60e-01 | 100.0% | 35.7% |
| 4138932 | 304.48.1.72 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_N | 0.83 | 77.0 | 5.44e-01 | 100.0% | 35.3% |
| 5078830 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.79 | 64.0 | 4.72e-01 | 86.8% | 38.5% |
| 3693017 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.71 | 64.0 | 4.41e-01 | 100.0% | 70.3% |
| 3598902 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.71 | 63.0 | 4.33e-01 | 100.0% | 30.8% |
| 3209439 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.70 | 63.0 | 4.50e-01 | 100.0% | 67.8% |
| 3792091 | 304.48.1.25 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4 | 0.70 | 63.0 | 4.41e-01 | 100.0% | 33.9% |
| 2757968 | 304.48.1.12 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Mononeg_RNA_pol | 0.70 | 63.0 | 4.95e-01 | 100.0% | 60.9% |
| 3615272 | 304.48.1.25 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4 | 0.70 | 62.0 | 4.26e-01 | 100.0% | 30.6% |
| 3097450 | 304.48.1.12 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Mononeg_RNA_pol | 0.69 | 62.0 | 4.19e-01 | 100.0% | 31.9% |
| 4262041 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.66 | 49.0 | 3.60e-01 | 100.0% | 31.8% |
| 3304359 | 304.48.1.70 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Intron_maturas2 | 0.65 | 59.0 | 3.78e-01 | 100.0% | 40.6% |
| 2850105 | 304.48.1.19 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Bunya_RdRp | 0.64 | 57.0 | 4.33e-01 | 100.0% | 69.9% |
| 4434853 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.64 | 46.0 | 3.50e-01 | 100.0% | 33.3% |
| 223786 | 304.48.1.16 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_4 | 0.62 | 55.0 | 3.93e-01 | 100.0% | 35.3% |
| 4070164 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.62 | 45.0 | 3.07e-01 | 100.0% | 22.5% |
| 5368 | 304.48.1.23 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_5 | 0.60 | 54.0 | 3.68e-01 | 100.0% | 30.8% |
| 4441043 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.57 | 45.0 | 3.94e-01 | 85.8% | 67.5% |
| 3284000 | 4107.1.1.2 ↗ | alpha arrays › Jann2411-like › Jann2411-like › Jann2411-like › zf-CGNR | 0.55 | 47.0 | 4.01e-01 | 94.3% | 82.6% |
| 4250601 | 186.1.1.0 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N | 0.54 | 47.0 | 4.04e-01 | 97.2% | 100.0% |
| 57748 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.54 | 21.0 | 2.65e-01 | 94.3% | 50.8% |
| 3225917 | 2498.1.1.23 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M49 | 0.52 | 41.0 | 2.56e-01 | 86.8% | 84.7% |
D5
medium
residues 189-243
Domain cluster:
representative
CATH (22)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2doaA00 | 1.10.10.2670 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › E3 ubiquitin-protein ligase | 0.61 | 50.0 | 4.15e-01 | 98.2% | 50.0% |
| 2p1aB01 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.58 | 46.0 | 3.33e-01 | 85.5% | 46.6% |
| 1u61A00 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.57 | 48.0 | 3.76e-01 | 98.2% | 85.0% |
| 2zj2A03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.56 | 46.0 | 4.14e-01 | 100.0% | 81.0% |
| 4cgyA02 | 1.10.460.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 2 › Topoisomerase I, domain 2 | 0.56 | 46.0 | 3.30e-01 | 100.0% | 37.9% |
| 1u8vB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 45.0 | 3.17e-01 | 100.0% | 39.9% |
| 2rsxA00 | 3.10.450.420 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.55 | 47.0 | 3.42e-01 | 98.2% | 65.4% |
| 2m72A00 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.55 | 37.0 | 2.79e-01 | 70.9% | 100.0% |
| 1e1hB01 | 1.20.58.540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 39.0 | 3.23e-01 | 74.5% | 79.6% |
| 3hdeC00 | 1.10.530.40 | Mainly Alpha › Orthogonal Bundle › Lysozyme › | 0.55 | 40.0 | 2.94e-01 | 80.0% | 37.2% |
| 1v7wA03 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.54 | 43.0 | 2.69e-01 | 94.5% | 14.0% |
| 4tv7D01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 41.0 | 3.63e-01 | 90.9% | 56.5% |
| 1gu2A00 | 1.10.760.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome Bc1 Complex; Chain D, domain 2 › Cytochrome c-like domain | 0.53 | 40.0 | 3.34e-01 | 94.5% | 82.3% |
| 6ketA01 | 3.20.20.30 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain | 0.52 | 41.0 | 2.52e-01 | 85.5% | 16.8% |
| 8jj7A01 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.52 | 43.0 | 2.78e-01 | 100.0% | 72.9% |
| 3llcA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.52 | 38.0 | 2.49e-01 | 78.2% | 37.9% |
| 2o7iA03 | 3.10.105.10 | Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 | 0.51 | 41.0 | 2.77e-01 | 96.4% | 54.7% |
| 3robA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.50 | 34.0 | 2.74e-01 | 72.7% | 94.7% |
| 2cqkA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.50 | 39.0 | 3.30e-01 | 94.5% | 48.5% |
| 5lohA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.50 | 41.0 | 2.97e-01 | 94.5% | 44.9% |
| 1p65A00 | 6.10.140.90 | Special › Helix non-globular › Helix Hairpins › | 0.50 | 37.0 | 3.70e-01 | 80.0% | 77.2% |
| 2dbuB00 | 3.60.20.40 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Gamma-glutamyltranspeptidase, small (S) subunit | 0.50 | 39.0 | 2.75e-01 | 98.2% | 25.8% |
ECOD (33)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3989356 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.95 | 86.0 | 5.70e-01 | 100.0% | 28.6% |
| 3258201 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.87 | 79.0 | 5.08e-01 | 100.0% | 25.1% |
| 4000704 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.74 | 64.0 | 4.44e-01 | 100.0% | 31.1% |
| 3478703 | 192.29.1.24 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM237 | 0.67 | 45.0 | 3.11e-01 | 70.9% | 79.0% |
| 3488729 | 4964.1.1.2 ↗ | alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › RNA_pol | 0.66 | 41.0 | 2.79e-01 | 74.5% | 16.3% |
| 3930943 | 2004.1.1.33 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C,RecQ_Zn_bind | 0.66 | 46.0 | 3.05e-01 | 74.5% | 35.2% |
| 3834374 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.64 | 59.0 | 3.48e-01 | 100.0% | 14.0% |
| 10173 | 2011.1.1.11 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M42 | 0.62 | 36.0 | 3.45e-01 | 74.5% | 48.4% |
| 5061395 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.62 | 44.0 | 4.49e-01 | 94.5% | 78.2% |
| 4192750 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.60 | 41.0 | 3.02e-01 | 70.9% | 28.1% |
| 3187085 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.60 | 52.0 | 4.48e-01 | 100.0% | 67.8% |
| 3600582 | 2003.1.7.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like | 0.60 | 40.0 | 2.60e-01 | 83.6% | 13.7% |
| 3596835 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.57 | 46.0 | 4.08e-01 | 100.0% | 61.2% |
| 4457163 | 109.3.1.20 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2,Ank_4 | 0.57 | 50.0 | 3.60e-01 | 96.4% | 49.3% |
| 4340549 | 3236.1.1.5 ↗ | alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_antiport_1 | 0.57 | 48.0 | 2.92e-01 | 100.0% | 49.4% |
| 3697894 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.56 | 42.0 | 2.49e-01 | 83.6% | 11.1% |
| 3716486 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.56 | 43.0 | 3.92e-01 | 96.4% | 62.7% |
| 3363271 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.56 | 37.0 | 3.80e-01 | 87.3% | 76.0% |
| 3715885 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.56 | 42.0 | 3.17e-01 | 81.8% | 33.6% |
| 3176813 | 148.1.1.74 ↗ | alpha arrays › Histone-like › Histone-related › Histone › PF29498 | 0.56 | 46.0 | 3.66e-01 | 94.5% | 72.9% |
| 1758276 | 301.8.1.3 ↗ | a+b three layers › Bacillus chorismate mutase-like › 4'-phosphopantetheinyl transferase › 4'-phosphopantetheinyl transferase › AASDHPPT_N | 0.55 | 45.0 | 3.67e-01 | 96.4% | 60.9% |
| None | — | 0.54 | 37.0 | 2.57e-01 | 83.6% | 18.6% | |
| 4045825 | 1166.1.1.1 ↗ | alpha arrays › Potassium-transporting ATPase KdpC subunit › Potassium-transporting ATPase KdpC subunit › Potassium-transporting ATPase KdpC subunit › KdpC | 0.53 | 43.0 | 3.16e-01 | 100.0% | 58.9% |
| 3498627 | 7015.1.1.1 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › DHHC | 0.53 | 45.0 | 2.99e-01 | 100.0% | 78.8% |
| 4027787 | 616.1.1.1 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Ribosomal_S15 | 0.52 | 45.0 | 3.12e-01 | 98.2% | 49.2% |
| 4251053 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.51 | 43.0 | 2.85e-01 | 100.0% | 74.1% |
| 2754401 | 3343.1.1.2 ↗ | alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal | 0.51 | 42.0 | 2.44e-01 | 100.0% | 16.9% |
| 4436275 | 632.1.1.32 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › TMEM208_SND2 | 0.51 | 41.0 | 3.42e-01 | 100.0% | 74.8% |
| 3309023 | 386.1.1.57 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › TRAFD1-XIAF1_ZnF | 0.51 | 38.0 | 3.17e-01 | 87.3% | 44.5% |
| 4588732 | 4023.1.1.1 ↗ | a+b two layers › N-terminal a+b domain in DNA primase core › N-terminal a+b domain in DNA primase core › N-terminal a+b domain in DNA primase core › DNAG_N | 0.51 | 41.0 | 3.19e-01 | 94.5% | 70.4% |
| 4146735 | 219.1.1.159 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › DUF6005 | 0.50 | 38.0 | 2.89e-01 | 96.4% | 30.0% |
| 3529112 | 109.4.1.593 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HPS6_C | 0.50 | 37.0 | 2.41e-01 | 83.6% | 16.9% |
| 3177987 | 109.4.1.549 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SAPS | 0.50 | 39.0 | 2.22e-01 | 83.6% | 14.9% |