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b-family_DNA_polymerase
Euk-VirPandoravirus_inopinatum
b-family_DNA_polymerase__YP_009120445__Pandoravirus_inopinatum__1605721
Identity
- Accession:
- YP_009120445 ↗
- Protein ID:
- b-family_DNA_polymerase
- Kingdom:
- euk
Quality
52.2
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 166-233_276-314_373-461
Domain cluster:
representative
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2gv9A03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.86 | 79.0 | 7.52e-01 | 94.4% | 100.0% |
| 3iayA03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.81 | 75.0 | 7.26e-01 | 95.4% | 100.0% |
| 4qclA03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.79 | 76.0 | 6.66e-01 | 99.5% | 84.5% |
| 4fvmA03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.78 | 72.0 | 6.70e-01 | 95.9% | 100.0% |
| 2a1rB01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.61 | 57.0 | 4.89e-01 | 99.0% | 91.1% |
| 2e1qC08 | 3.30.365.10 | Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain | 0.57 | 34.0 | 3.69e-01 | 95.4% | 67.6% |
| 5jr6A02 | 3.40.350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain | 0.56 | 36.0 | 4.08e-01 | 74.0% | 82.1% |
| 6m9yA00 | 3.30.1300.40 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › | 0.55 | 20.0 | 3.25e-01 | 92.9% | 100.0% |
| 3hrdA02 | 3.30.365.10 | Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain | 0.54 | 31.0 | 3.30e-01 | 100.0% | 61.6% |
| 1p7lA03 | 3.30.300.10 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › | 0.54 | 26.0 | 3.49e-01 | 93.4% | 84.0% |
| 1rm6A03 | 3.30.365.10 | Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain | 0.53 | 27.0 | 3.19e-01 | 85.7% | 68.9% |
| 3lmlA01 | 3.10.450.690 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.53 | 23.0 | 2.88e-01 | 91.8% | 62.8% |
| 1ffvB02 | 3.30.365.10 | Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain | 0.52 | 26.0 | 3.00e-01 | 85.7% | 62.8% |
| 6rptC00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.52 | 27.0 | 3.40e-01 | 99.5% | 83.9% |
| 2n3zA00 | 3.40.50.11230 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.51 | 25.0 | 3.37e-01 | 96.9% | 89.9% |
| 2hqlA01 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.51 | 22.0 | 3.05e-01 | 87.2% | 82.4% |
| 2z5bA00 | 3.30.230.100 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.50 | 33.0 | 3.97e-01 | 93.4% | 100.0% |
| 4mh4A02 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.50 | 24.0 | 3.31e-01 | 93.9% | 91.5% |
ECOD (33)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| None | — | 0.84 | 81.0 | 6.36e-01 | 99.0% | 62.5% | |
| 3710418 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.84 | 81.0 | 6.29e-01 | 99.0% | 60.8% |
| 3496492 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.84 | 81.0 | 6.91e-01 | 100.0% | 82.1% |
| 3206356 | 304.114.1.0 ↗ | a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain | 0.83 | 81.0 | 6.14e-01 | 100.0% | 60.5% |
| 3825992 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.83 | 80.0 | 7.23e-01 | 99.5% | 92.8% |
| 3797773 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.82 | 79.0 | 6.73e-01 | 100.0% | 80.3% |
| 4023334 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.82 | 79.0 | 6.83e-01 | 100.0% | 86.4% |
| 3684974 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.82 | 79.0 | 5.24e-01 | 100.0% | 36.8% |
| 3705562 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.82 | 78.0 | 5.18e-01 | 99.0% | 34.5% |
| 3193111 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.81 | 78.0 | 6.06e-01 | 100.0% | 64.2% |
| 3784398 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.81 | 77.0 | 6.96e-01 | 99.0% | 92.9% |
| 3606428 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.81 | 77.0 | 7.14e-01 | 98.5% | 95.3% |
| 3404726 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.81 | 78.0 | 6.60e-01 | 100.0% | 81.0% |
| 3692564 | 2.1.1.25 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_B_exo1 | 0.81 | 78.0 | 5.88e-01 | 100.0% | 58.8% |
| 3168836 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.80 | 77.0 | 6.91e-01 | 99.5% | 93.3% |
| 3192875 | 304.114.1.0 ↗ | a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain | 0.80 | 77.0 | 5.55e-01 | 100.0% | 56.9% |
| 3794217 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.79 | 76.0 | 5.37e-01 | 100.0% | 59.8% |
| 4002044 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.79 | 76.0 | 6.12e-01 | 100.0% | 70.9% |
| 3932596 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.79 | 75.0 | 6.96e-01 | 99.0% | 95.3% |
| 3214818 | 304.114.1.0 ↗ | a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain | 0.79 | 75.0 | 5.84e-01 | 99.0% | 58.9% |
| 5066483 | 2484.1.1.68 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 | 0.74 | 63.0 | 6.72e-01 | 98.0% | 100.0% |
| 4957483 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.72 | 68.0 | 6.77e-01 | 98.5% | 98.5% |
| 4990754 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.71 | 68.0 | 6.48e-01 | 100.0% | 87.6% |
| 5076410 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.71 | 68.0 | 5.34e-01 | 100.0% | 88.1% |
| 4420719 | 2484.1.1.45 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › CAF1 | 0.62 | 58.0 | 4.75e-01 | 99.0% | 86.3% |
| 3735502 | 2484.1.1.45 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › CAF1 | 0.61 | 57.0 | 4.64e-01 | 99.0% | 87.7% |
| 3995965 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.60 | 43.0 | 4.51e-01 | 98.5% | 78.4% |
| 3428834 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.59 | 55.0 | 4.80e-01 | 100.0% | 95.2% |
| 3513469 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.59 | 26.0 | 2.97e-01 | 97.4% | 53.8% |
| 4016644 | 11.8.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Osmotin-like › Osmotin-like | 0.53 | 27.0 | 3.06e-01 | 96.9% | 61.7% |
| 3264336 | 277.1.1.0 ↗ | a+b two layers › PX domain › PX domain › PX domain | 0.52 | 25.0 | 3.53e-01 | 92.3% | 96.7% |
| 3627091 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.52 | 49.0 | 4.55e-01 | 100.0% | 88.3% |
| 3272654 | 11.1.4.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like | 0.50 | 23.0 | 3.00e-01 | 95.4% | 76.0% |
D2
medium
residues 315-372
D3
medium
residues 572-587_748-800
D4
medium
residues 588-703
D5
medium
residues 704-747
Domain cluster:
representative
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.91 | 76.0 | 5.70e-01 | 90.9% | 42.4% |
| 4gouA03 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.90 | 77.0 | 4.88e-01 | 93.2% | 21.3% |
| 1z0jB00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.88 | 78.0 | 7.40e-01 | 95.5% | 90.2% |
| 2yevA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.87 | 72.0 | 6.03e-01 | 90.9% | 59.5% |
| 3k6tB00 | 1.20.5.4010 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.86 | 74.0 | 7.12e-01 | 93.2% | 91.8% |
| 4aifA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.84 | 74.0 | 5.06e-01 | 97.7% | 72.2% |
| 3pt1A02 | 1.20.930.60 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.84 | 71.0 | 5.16e-01 | 95.5% | 35.8% |
| 3fnbA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.83 | 70.0 | 5.11e-01 | 93.2% | 37.7% |
| 3tklB01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.83 | 75.0 | 6.65e-01 | 100.0% | 72.6% |
| 2p4vA01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.83 | 74.0 | 6.13e-01 | 100.0% | 67.1% |
| 2gv9A05 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.82 | 72.0 | 6.53e-01 | 100.0% | 72.9% |
| 3hiuD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.82 | 68.0 | 4.63e-01 | 93.2% | 27.6% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.81 | 71.0 | 6.40e-01 | 100.0% | 72.4% |
| 2o8pA00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.81 | 72.0 | 4.53e-01 | 100.0% | 21.9% |
| 2rkhA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.80 | 73.0 | 5.98e-01 | 100.0% | 57.9% |
| 2pusA02 | 1.10.287.540 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.80 | 61.0 | 5.77e-01 | 90.9% | 69.8% |
| 4ehsA00 | 1.10.860.10 | Mainly Alpha › Orthogonal Bundle › DNAb Helicase; Chain A › DNAb Helicase; Chain A | 0.79 | 60.0 | 4.27e-01 | 81.8% | 34.7% |
| 8jx6A02 | 2.30.30.780 | Mainly Beta › Roll › SH3 type barrels. › | 0.79 | 62.0 | 4.68e-01 | 100.0% | 36.9% |
| 5nohA00 | 1.20.120.1350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain | 0.76 | 64.0 | 4.85e-01 | 93.2% | 39.8% |
| 3kflA02 | 2.170.220.10 | Mainly Beta › Beta Complex › Methionyl-trna Synthetase; domain 2 › | 0.73 | 52.0 | 3.74e-01 | 86.4% | 27.3% |
| 5b1oA00 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.73 | 56.0 | 5.11e-01 | 90.9% | 63.1% |
| 6tkvA01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.71 | 59.0 | 5.22e-01 | 100.0% | 75.0% |
| 2ckoA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.68 | 56.0 | 3.52e-01 | 100.0% | 54.5% |
| 2l37A00 | 6.10.250.890 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.64 | 52.0 | 5.28e-01 | 90.9% | 95.3% |
| 2wmmA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.62 | 47.0 | 4.62e-01 | 93.2% | 81.6% |
| 1vkcA01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.62 | 51.0 | 3.64e-01 | 95.5% | 82.0% |
| 1vibA00 | 1.10.287.120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Neurotoxin B-IV-like | 0.61 | 49.0 | 4.64e-01 | 95.5% | 74.5% |
ECOD (62)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| None | — | 0.95 | 78.0 | 4.85e-01 | 88.6% | 18.6% | |
| 4485576 | 1.1.17.4 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Peptidase_S64 | 0.94 | 84.0 | 4.92e-01 | 95.5% | 14.5% |
| 4999065 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.92 | 86.0 | 5.68e-01 | 100.0% | 64.5% |
| 3956669 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.92 | 86.0 | 5.47e-01 | 100.0% | 52.8% |
| 3955489 | 2484.1.1.211 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605, Cas12f1-like_TNB | 0.91 | 84.0 | 5.21e-01 | 100.0% | 43.8% |
| 4667859 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.91 | 78.0 | 5.61e-01 | 93.2% | 36.5% |
| 4977784 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.90 | 83.0 | 5.06e-01 | 100.0% | 44.7% |
| 5017725 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.90 | 82.0 | 5.21e-01 | 100.0% | 45.6% |
| 4202466 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.90 | 75.0 | 7.48e-01 | 90.9% | 91.1% |
| 3983659 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.90 | 75.0 | 6.48e-01 | 90.9% | 61.5% |
| 3651038 | 192.29.1.221 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29520 | 0.90 | 82.0 | 5.68e-01 | 100.0% | 70.0% |
| 3714352 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.89 | 81.0 | 5.77e-01 | 100.0% | 60.8% |
| 4972401 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.89 | 82.0 | 5.06e-01 | 100.0% | 42.8% |
| 4977369 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.89 | 81.0 | 4.90e-01 | 100.0% | 24.0% |
| 4996586 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.89 | 80.0 | 5.49e-01 | 100.0% | 65.0% |
| 4959101 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.89 | 81.0 | 4.91e-01 | 100.0% | 22.9% |
| 4998819 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.88 | 81.0 | 5.62e-01 | 100.0% | 66.9% |
| 4999337 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.88 | 80.0 | 5.33e-01 | 100.0% | 57.4% |
| 3348106 | 5076.2.1.10 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 | 0.88 | 81.0 | 4.85e-01 | 100.0% | 16.7% |
| 5005094 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.88 | 79.0 | 5.06e-01 | 100.0% | 45.6% |
| 3503355 | 3730.1.1.0 ↗ | alpha arrays › CCM3/GCKIII dimerization domain › CCM3/GCKIII dimerization domain › CCM3/GCKIII dimerization domain | 0.88 | 73.0 | 6.74e-01 | 90.9% | 74.5% |
| 3519300 | 1147.1.1.1 ↗ | alpha bundles › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › Occludin_ELL | 0.87 | 72.0 | 5.16e-01 | 90.9% | 33.3% |
| 3913004 | 3729.1.1.2 ↗ | alpha arrays › Legumain prodomain › Legumain prodomain › Legumain prodomain › MREG | 0.87 | 79.0 | 5.28e-01 | 100.0% | 31.0% |
| 3240265 | 2004.1.1.184 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 | 0.86 | 77.0 | 4.56e-01 | 100.0% | 14.6% |
| 4544002 | 192.6.1.1 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATP-synt_DE | 0.86 | 72.0 | 6.94e-01 | 93.2% | 84.0% |
| 3755476 | 3755.1.1.0 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related | 0.86 | 73.0 | 4.77e-01 | 93.2% | 24.0% |
| 4213046 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.86 | 79.0 | 6.80e-01 | 100.0% | 69.2% |
| 4978165 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.86 | 77.0 | 4.87e-01 | 100.0% | 44.5% |
| 3219691 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.85 | 69.0 | 5.94e-01 | 90.9% | 58.6% |
| 3676043 | 5076.2.1.10 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 | 0.85 | 76.0 | 4.54e-01 | 100.0% | 15.8% |
| 4539096 | 109.4.1.603 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TAF1_subA | 0.85 | 70.0 | 3.99e-01 | 90.9% | 10.2% |
| 5051266 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.85 | 74.0 | 4.67e-01 | 100.0% | 40.4% |
| 3192393 | 2004.1.1.430 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, ABC_tran_Xtn | 0.84 | 76.0 | 4.16e-01 | 100.0% | 7.3% |
| 3714091 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.84 | 70.0 | 5.87e-01 | 93.2% | 56.0% |
| 4936910 | 3939.1.1.145 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › GrpE | 0.84 | 67.0 | 5.08e-01 | 90.9% | 38.1% |
| 4300120 | 605.1.1.108 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › GrpE | 0.84 | 68.0 | 6.33e-01 | 90.9% | 72.7% |
| 3346803 | 5076.2.1.10 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 | 0.83 | 74.0 | 4.39e-01 | 100.0% | 28.9% |
| 4536765 | 605.1.1.108 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › GrpE | 0.83 | 68.0 | 5.18e-01 | 90.9% | 40.0% |
| 5032045 | 4163.1.1.0 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like | 0.83 | 74.0 | 5.63e-01 | 100.0% | 48.0% |
| 3471215 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.83 | 73.0 | 6.06e-01 | 97.7% | 58.7% |
| 3622515 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.82 | 74.0 | 5.89e-01 | 100.0% | 52.9% |
| 3719591 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.81 | 71.0 | 4.48e-01 | 97.7% | 20.9% |
| 3495960 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.81 | 71.0 | 4.69e-01 | 100.0% | 40.6% |
| 4674738 | 133.1.1.0 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) | 0.81 | 73.0 | 4.55e-01 | 100.0% | 21.8% |
| 4809777 | 6004.1.1.2 ↗ | extended segments › FATC domain › FATC domain › FATC domain › ETC_C1_NDUFA5 | 0.81 | 64.0 | 4.86e-01 | 90.9% | 36.7% |
| 3722750 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.81 | 67.0 | 3.96e-01 | 93.2% | 14.4% |
| 3937759 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.80 | 65.0 | 5.60e-01 | 90.9% | 58.6% |
| 3615269 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.80 | 70.0 | 4.43e-01 | 97.7% | 21.4% |
| 3177102 | 548.1.1.2 ↗ | alpha duplicates or obligate multimers › GRIP domain › GRIP domain › GRIP domain › GRAB | 0.80 | 58.0 | 5.93e-01 | 79.5% | 83.7% |
| 4951260 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.79 | 69.0 | 4.81e-01 | 100.0% | 32.9% |
| 3794795 | 603.1.1.3 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE | 0.79 | 66.0 | 5.15e-01 | 97.7% | 45.0% |
| 3604282 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.77 | 67.0 | 4.89e-01 | 100.0% | 36.7% |
| 4590389 | 4163.1.1.1 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 | 0.77 | 66.0 | 4.54e-01 | 100.0% | 29.0% |
| 3576943 | 11.12.1.2 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Nicotinic receptor ligand binding domain-like › Nicotinic receptor ligand binding domain-like › Neur_chan_LBD,Neur_chan_memb | 0.76 | 61.0 | 3.71e-01 | 90.9% | 14.6% |
| 3494602 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.76 | 60.0 | 3.29e-01 | 93.2% | 5.2% |
| 3224003 | 9001.1.1.3 ↗ | alpha bundles › TMEM120/ELO/TLC › TMEM120/ELO/TLC › TMEM120/ELO/TLC › TMPIT | 0.76 | 64.0 | 5.35e-01 | 100.0% | 56.2% |
| 3931593 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.75 | 65.0 | 5.40e-01 | 100.0% | 56.2% |
| 3678444 | 5076.2.1.10 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 | 0.74 | 63.0 | 3.84e-01 | 100.0% | 33.1% |
| 3979215 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.74 | 52.0 | 4.83e-01 | 75.0% | 78.2% |
| 4229778 | 3390.1.1.0 ↗ | extended segments › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT | 0.67 | 53.0 | 5.15e-01 | 90.9% | 100.0% |
| 4902869 | 101.1.2.22 ↗ | alpha arrays › HTH › HTH › winged helix domain › PCI | 0.67 | 50.0 | 4.41e-01 | 93.2% | 51.9% |
| 3757999 | 219.1.1.9 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C12 | 0.63 | 50.0 | 3.07e-01 | 100.0% | 14.2% |