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cathepsin
Euk-VirCryptophlebia_peltastica_nucleopolyhedrovirus
cathepsin__YP_010086926__Cryptophlebia_peltastica_nucleopolyhedrovirus__2304025
Identity
- Accession:
- YP_010086926 ↗
- Protein ID:
- cathepsin
- Kingdom:
- euk
Quality
79.3
mean pLDDT
Taxonomy
Naldaviricetes›
Lefavirales›
Baculoviridae›
Alphabaculovirus›
Cryptophlebia_peltastica_nucleopolyhedrovirus
TaxID: 2304025
Cluster
View cluster (48 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 112-334
Domain cluster:
rep: SR-VP_0-2_scaffold_141_4750547_curated_closed_complete_prodigal-single.1__X__X__00914__D21-264
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00112.30 best | Peptidase_C1 | 244.9 | 1.50e-72 | 93.7% | 98.6% |
D2
medium
residues 22-71
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF08246.18 best | Inhibitor_I29 | 39.7 | 7.00e-10 | 80.0% | 67.8% |
CATH (31)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3f75P00 | 1.10.287.2250 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.94 | 83.0 | 7.09e-01 | 94.0% | 65.3% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.80 | 55.0 | 4.07e-01 | 72.0% | 83.9% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.76 | 55.0 | 4.18e-01 | 76.0% | 41.8% |
| 4fybA00 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.73 | 57.0 | 3.93e-01 | 84.0% | 69.6% |
| 3n5lA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 51.0 | 4.93e-01 | 74.0% | 78.9% |
| 4oe8C00 | 1.10.8.1170 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.71 | 58.0 | 4.84e-01 | 90.0% | 90.8% |
| 5nohA00 | 1.20.120.1350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain | 0.70 | 54.0 | 4.25e-01 | 84.0% | 98.1% |
| 6l4lA01 | 3.10.310.10 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 | 0.69 | 42.0 | 3.25e-01 | 90.0% | 26.7% |
| 2wdqC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.67 | 58.0 | 4.41e-01 | 100.0% | 42.1% |
| 2wmmA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.65 | 51.0 | 5.23e-01 | 98.0% | 85.7% |
| 2yfqB01 | 1.10.8.1210 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.65 | 44.0 | 4.34e-01 | 82.0% | 67.3% |
| 3kfwX03 | 1.20.58.1460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 45.0 | 3.90e-01 | 74.0% | 68.4% |
| 1euvA01 | 1.10.418.20 | Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › | 0.63 | 50.0 | 3.98e-01 | 90.0% | 74.3% |
| 3qc1A01 | 1.25.40.540 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family | 0.62 | 55.0 | 3.83e-01 | 100.0% | 31.8% |
| 2bg1A01 | 3.90.1310.40 | Alpha Beta › Alpha-Beta Complex › Penicillin-binding protein 2a (Domain 2) › | 0.62 | 48.0 | 4.34e-01 | 92.0% | 89.6% |
| 7ar7T01 | 1.10.1200.10 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like | 0.62 | 42.0 | 3.79e-01 | 84.0% | 48.0% |
| 7e42A01 | 1.10.1200.10 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like | 0.62 | 41.0 | 3.64e-01 | 86.0% | 45.9% |
| 3n4eA01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.62 | 49.0 | 3.88e-01 | 96.0% | 42.3% |
| 2zxqA06 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.62 | 51.0 | 4.61e-01 | 90.0% | 93.9% |
| 2jpnA00 | 1.20.1280.210 | Mainly Alpha › Up-down Bundle › Monooxygenase › Uncharacterised protein UvsW.1 | 0.62 | 46.0 | 3.99e-01 | 82.0% | 57.0% |
| 5u1xA01 | 1.10.287.940 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel | 0.61 | 50.0 | 5.14e-01 | 92.0% | 100.0% |
| 4ex8A00 | 3.40.1790.10 | Alpha Beta › 3-Layer(aba) Sandwich › Indigoidine synthase fold › Indigoidine synthase domain | 0.61 | 51.0 | 3.20e-01 | 100.0% | 60.8% |
| 3gd6A01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.61 | 49.0 | 3.56e-01 | 96.0% | 31.7% |
| 4uqfG01 | 1.10.286.10 | Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 › GTP cyclohydrolase I, N-terminal domain | 0.59 | 46.0 | 4.65e-01 | 100.0% | 94.2% |
| 1sxjE02 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.59 | 42.0 | 3.96e-01 | 78.0% | 60.9% |
| 2cg8B02 | 3.30.70.560 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK | 0.58 | 43.0 | 3.23e-01 | 80.0% | 51.5% |
| 2b8iA00 | 1.20.1280.100 | Mainly Alpha › Up-down Bundle › Monooxygenase › Pas factor, saposin domain | 0.58 | 44.0 | 3.94e-01 | 92.0% | 57.1% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.55 | 47.0 | 3.72e-01 | 100.0% | 47.1% |
| 2og9A01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.54 | 45.0 | 3.39e-01 | 96.0% | 86.2% |
| 3lyeA00 | 3.20.20.60 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains | 0.53 | 44.0 | 2.83e-01 | 100.0% | 85.3% |
| 1bjaA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.50 | 37.0 | 3.19e-01 | 88.0% | 96.8% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3509928 | 219.1.1.0 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases | 0.96 | 84.0 | 4.76e-01 | 92.0% | 11.9% |
| 3929741 | 3998.1.1.1 ↗ | alpha arrays › Peptidase inhibitors family I29 › Peptidase inhibitors family I29 › Peptidase inhibitors family I29 › Inhibitor_I29 | 0.96 | 85.0 | 7.42e-01 | 94.0% | 68.6% |
| 3317130 | 3998.1.1.1 ↗ | alpha arrays › Peptidase inhibitors family I29 › Peptidase inhibitors family I29 › Peptidase inhibitors family I29 › Inhibitor_I29 | 0.95 | 90.0 | 7.46e-01 | 100.0% | 66.3% |
| 3299336 | 219.1.1.0 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases | 0.95 | 89.0 | 5.28e-01 | 100.0% | 16.8% |
| 3470140 | 3998.1.1.1 ↗ | alpha arrays › Peptidase inhibitors family I29 › Peptidase inhibitors family I29 › Peptidase inhibitors family I29 › Inhibitor_I29 | 0.90 | 79.0 | 6.82e-01 | 96.0% | 68.0% |
| 3671126 | 148.1.1.0 ↗ | alpha arrays › Histone-like › Histone-related › Histone | 0.83 | 74.0 | 5.76e-01 | 100.0% | 56.2% |
| 3420861 | 5076.2.1.10 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 | 0.78 | 67.0 | 4.08e-01 | 96.0% | 98.3% |
| 5017300 | 283.2.1.0 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like | 0.77 | 68.0 | 5.12e-01 | 100.0% | 46.7% |
| 4948481 | 247.1.1.1 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B | 0.76 | 65.0 | 4.06e-01 | 96.0% | 19.9% |
| 5060990 | 2005.1.1.18 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › NAD_synthase | 0.74 | 64.0 | 4.03e-01 | 98.0% | 18.3% |
| 4626442 | 7010.1.1.0 ↗ | alpha arrays › Activation-binding domain of RNA polymerase II mediator › Activation-binding domain of RNA polymerase II mediator › Activation-binding domain of RNA polymerase II mediator | 0.74 | 63.0 | 6.02e-01 | 98.0% | 93.3% |
| 4959086 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.73 | 51.0 | 4.46e-01 | 74.0% | 81.3% |
| 3518339 | 101.1.1.1 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain | 0.72 | 57.0 | 6.03e-01 | 96.0% | 93.3% |
| 3644522 | 397.7.1.5 ↗ | few secondary structure elements › Toxic hairpin › Ribosome-inactivating protein luffin P1 › Ribosome-inactivating protein luffin P1 › DUF7067 | 0.72 | 58.0 | 5.54e-01 | 92.0% | 78.3% |
| 3974778 | 191.1.1.11 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_7 | 0.72 | 61.0 | 4.47e-01 | 98.0% | 90.6% |
| 3552184 | 1045.1.1.1 ↗ | alpha bundles › Rad50-binding domain of Mre11 › Rad50-binding domain of Mre11 › Rad50-binding domain of Mre11 › Mre11_DNA_bind | 0.67 | 54.0 | 4.29e-01 | 90.0% | 62.9% |
| 3685082 | 4120.1.1.53 ↗ | few secondary structure elements › Tim10/DDP › Tim10/DDP › Tim10/DDP › AA_permease_2 | 0.67 | 57.0 | 3.78e-01 | 96.0% | 24.9% |
| 3909150 | 5063.1.1.15 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › OCIA | 0.67 | 56.0 | 5.05e-01 | 100.0% | 69.3% |
| 4136321 | 101.35.1.0 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX | 0.66 | 53.0 | 4.94e-01 | 100.0% | 69.2% |
| 3260418 | 5043.1.1.0 ↗ | extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like | 0.65 | 54.0 | 5.10e-01 | 100.0% | 84.6% |
| 3798181 | 1188.1.1.0 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter | 0.65 | 54.0 | 3.50e-01 | 100.0% | 77.3% |
| 5024109 | 3646.1.1.1 ↗ | alpha complex topology › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters › CbiQ | 0.65 | 55.0 | 3.62e-01 | 100.0% | 21.8% |
| 3270778 | 108.1.1.96 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1, EF-hand_6, EF-hand_7 | 0.61 | 52.0 | 4.26e-01 | 100.0% | 51.0% |
| 3593000 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.61 | 50.0 | 4.27e-01 | 100.0% | 55.3% |
| 3259715 | 5071.1.1.1 ↗ | alpha bundles › cytochrome bc1 complex 11 kDa protein-like › Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › UCR_hinge | 0.59 | 43.0 | 3.82e-01 | 74.0% | 56.5% |
| 3592370 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.59 | 49.0 | 3.76e-01 | 96.0% | 59.2% |
| 3927475 | 192.19.1.0 ↗ | alpha bundles › Long alpha-hairpin › YnzC-like › YnzC-like | 0.56 | 43.0 | 4.18e-01 | 84.0% | 96.4% |
| 3925160 | 9.26.1.0 ↗ | beta barrels › Lipocalins/Streptavidin | 0.51 | 43.0 | 2.95e-01 | 100.0% | 25.8% |