←Back to structures

chemokine_vCXCL2

Euk-Vir

Panine_betaherpesvirus_2

chemokine_vCXCL2__NP_612754__Panine_betaherpesvirus_2__188763

Identity

Accession:
NP_612754 ↗
Protein ID:
chemokine_vCXCL2
Kingdom:
euk

Quality

78.3 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Cytomegalovirus› Panine_betaherpesvirus_2

TaxID: 188763

Cluster

View cluster (7 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 100-147
PDB
Domain cluster: representative
CATH (34)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
8a9nA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.68 54.0 4.05e-01 93.8% 38.9%
2fe7B00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.62 50.0 3.55e-01 95.8% 30.1%
2euiA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.62 53.0 3.86e-01 100.0% 37.1%
2iz4A02 2.20.25.590 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.62 41.0 4.34e-01 95.8% 78.6%
1cjaA02 1.10.1070.11 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain 0.60 52.0 3.56e-01 100.0% 74.6%
3venA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.60 47.0 3.06e-01 87.5% 78.5%
2gumB03 2.30.29.100 Mainly Beta › Roll › PH-domain like › 0.58 42.0 3.26e-01 81.2% 69.4%
4lvnP00 3.30.70.2380 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 42.0 3.66e-01 93.8% 48.1%
1wxrA03 3.30.160.280 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.58 43.0 3.78e-01 83.3% 78.9%
1pvgA01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.58 50.0 3.20e-01 100.0% 70.5%
3gd6A01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.58 50.0 3.63e-01 100.0% 38.0%
3qf7A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 44.0 2.72e-01 85.4% 25.5%
4dcmA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 46.0 3.10e-01 91.7% 48.1%
1zxuA00 2.40.160.200 Mainly Beta › Beta Barrel › Porin › LURP1-related 0.56 47.0 3.26e-01 93.8% 100.0%
3obaA03 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.56 42.0 2.59e-01 81.2% 94.9%
1lgpA00 2.60.200.20 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.55 34.0 2.70e-01 81.2% 24.8%
3n0vA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.55 40.0 3.51e-01 83.3% 83.3%
4wfsA01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.55 43.0 2.85e-01 89.6% 21.6%
3g2bA00 1.10.10.1150 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Coenzyme PQQ synthesis protein D (PqqD) 0.55 45.0 3.70e-01 93.8% 51.1%
1ddvA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.55 46.0 3.62e-01 95.8% 96.2%
7o85C01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 35.0 3.18e-01 87.5% 41.6%
2dulA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 42.0 2.61e-01 100.0% 13.3%
3hkoA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.54 41.0 2.75e-01 87.5% 79.2%
4hdoA03 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.53 47.0 3.80e-01 100.0% 93.5%
8b4hA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.53 42.0 3.10e-01 100.0% 78.4%
3dsbA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.53 40.0 3.18e-01 83.3% 44.6%
7uqyB01 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.52 43.0 2.87e-01 95.8% 47.2%
2qlzA02 6.10.250.2960 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.52 47.0 3.84e-01 100.0% 67.4%
3rhtA00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.52 42.0 2.74e-01 93.8% 94.8%
3zf8A00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.51 43.0 2.71e-01 100.0% 17.4%
1neiA00 3.30.160.220 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YoaG 0.51 41.0 3.88e-01 100.0% 76.7%
2g0iA00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.51 45.0 3.43e-01 100.0% 43.2%
1gpqB00 3.40.1420.10 Alpha Beta › 3-Layer(aba) Sandwich › Inhibitor of vertebrate lysozyme, Ivy › Inhibitor of vertebrate lysozyme 0.51 39.0 3.01e-01 89.6% 75.8%
4xcmA02 3.90.1720.10 Alpha Beta › Alpha-Beta Complex › endopeptidase fold (from Nostoc punctiforme) › endopeptidase domain like (from Nostoc punctiforme) 0.50 37.0 2.82e-01 81.2% 35.0%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3618688 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.70 46.0 2.78e-01 70.8% 10.3%
3212521 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.68 49.0 2.98e-01 79.2% 14.8%
3999372 198.1.1.4 ↗ alpha arrays › Saposin-like › Saposin-like › Saposin-like › DUF3456 0.67 56.0 4.15e-01 93.8% 72.8%
2389835 312.1.1.1 ↗ a+b three layers › HIT-like › HIT-related › HIT-related › GalP_UDP_transf 0.66 57.0 3.94e-01 100.0% 43.9%
4004358 252.2.1.3 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › Arm-DNA-bind_1 0.66 47.0 4.65e-01 75.0% 96.0%
4996777 7515.1.1.2 ↗ a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Sulfatase 0.65 54.0 3.14e-01 91.7% 17.0%
None — 0.65 53.0 3.15e-01 91.7% 43.4%
3792300 7579.1.1.23 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › PAF-AH_p_II 0.65 53.0 3.15e-01 93.8% 42.0%
None — 0.65 51.0 3.70e-01 93.8% 38.7%
5038306 312.1.1.0 ↗ a+b three layers › HIT-like › HIT-related › HIT-related 0.65 55.0 4.59e-01 100.0% 90.0%
4383296 318.1.1.1 ↗ a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal_L6 0.65 49.0 4.29e-01 95.8% 52.5%
3246096 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.64 51.0 3.07e-01 89.6% 21.6%
None — 0.64 53.0 3.13e-01 93.8% 45.0%
5062611 213.1.1.1 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 0.63 50.0 3.58e-01 93.8% 31.4%
5078639 3926.1.1.1 ↗ alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D › ATP-synt_D 0.62 52.0 3.60e-01 100.0% 32.1%
4517021 2004.1.2.2 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › PEP carboxykinase catalytic C-terminal domain › PEPCK_ATP 0.62 49.0 3.04e-01 89.6% 30.4%
4046039 318.1.1.1 ↗ a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal_L6 0.62 49.0 4.18e-01 100.0% 51.8%
3261599 4272.1.1.1 ↗ a+b two layers › Nqo5-like › Nqo5-like › Nqo5-like › Complex1_30kDa 0.62 51.0 3.46e-01 100.0% 47.1%
3739438 213.1.1.1 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 0.61 52.0 3.65e-01 100.0% 31.0%
4027429 4.1.1.41 ↗ beta barrels › SH3 › SH3 › SH3 › NOT2_3_5_C 0.61 46.0 3.08e-01 83.3% 54.9%
3517822 7523.1.1.0 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.60 51.0 3.96e-01 100.0% 43.5%
5068337 2004.1.1.42 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE 0.60 48.0 3.06e-01 87.5% 86.9%
3573556 2003.1.5.145 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › RLMG_N 0.60 44.0 2.83e-01 97.9% 16.9%
3911142 263.1.1.0 ↗ a+b three layers › SRF-like › SRF-like › SRF-like 0.60 50.0 4.01e-01 93.8% 47.4%
3184113 318.1.1.0 ↗ a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 0.59 47.0 3.88e-01 100.0% 46.0%
3716046 2004.1.1.250 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.59 51.0 2.96e-01 100.0% 22.5%
4943403 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.59 50.0 3.21e-01 93.8% 40.9%
3415739 64.1.1.0 ↗ beta meanders › WW domain-like › WW domain › WW domain 0.58 40.0 4.60e-01 70.8% 100.0%
4987009 3837.1.1.1 ↗ alpha bundles › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › DUF6847 0.57 47.0 3.35e-01 91.7% 34.0%
3677732 7512.1.1.6 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_20 0.57 48.0 2.76e-01 95.8% 19.6%
3224950 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.57 47.0 3.70e-01 93.8% 52.4%
1631501 217.1.1.2 ↗ a+b complex topology › FAD-binding domain-like › FAD-binding domain › FAD-binding domain › FAD_binding_4 0.57 38.0 2.40e-01 87.5% 11.4%
3723461 4099.1.1.9 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Med27 0.56 45.0 3.37e-01 97.9% 33.8%
2774534 4272.1.1.1 ↗ a+b two layers › Nqo5-like › Nqo5-like › Nqo5-like › Complex1_30kDa 0.56 45.0 3.06e-01 100.0% 41.4%
3232194 4272.1.1.1 ↗ a+b two layers › Nqo5-like › Nqo5-like › Nqo5-like › Complex1_30kDa 0.56 44.0 3.05e-01 100.0% 42.3%
5028275 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.56 49.0 2.95e-01 100.0% 25.2%
3199254 604.6.1.41 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF846 0.56 50.0 3.61e-01 100.0% 80.7%
3623534 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.55 49.0 3.97e-01 100.0% 100.0%
5076296 7573.1.1.1 ↗ a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › Pribosyltran 0.55 41.0 2.73e-01 79.2% 47.7%
3627795 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.55 48.0 4.01e-01 100.0% 84.7%
3506749 633.21.1.23 ↗ alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 0.55 45.0 3.19e-01 95.8% 46.1%
3435685 376.1.3.6 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › zf-CW 0.55 45.0 3.88e-01 89.6% 100.0%
3632364 603.1.1.120 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF846 0.55 49.0 3.38e-01 100.0% 66.1%
3271024 2003.1.5.73 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_16 0.54 43.0 2.99e-01 95.8% 50.5%
4394681 862.1.1.4 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › RepB_primase 0.54 49.0 3.18e-01 100.0% 64.4%
3249391 246.2.1.7 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › DNA_pol_E_B 0.54 46.0 2.81e-01 95.8% 18.5%
3253268 4.1.1.41 ↗ beta barrels › SH3 › SH3 › SH3 › NOT2_3_5_C 0.54 40.0 2.78e-01 81.2% 50.3%
3963172 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.53 42.0 2.90e-01 85.4% 49.3%
4406214 101.1.2.70 ↗ alpha arrays › HTH › HTH › winged helix domain › PqqD 0.53 43.0 3.57e-01 95.8% 49.5%
D2 medium residues 38-88
PDB
Domain cluster: rep: chemokine_vCXCL7__YP_004936092__Cercopithecine_betaherpesvirus_5__50292__D42-88
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00048.26 best IL8 21.5 2.90e-04 96.1% 78.3%