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conserved_putative_calcineurin-like_phosphoesterase

Euk-Vir

Melbournevirus

conserved_putative_calcineurin-like_phosphoesterase__YP_009094826__Melbournevirus__1560514

Identity

Accession:
YP_009094826 ↗
Protein ID:
conserved_putative_calcineurin-like_phosphoesterase
Kingdom:
euk

Quality

88.1 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Marseilleviridae› Marseillevirus› Marseillevirus_sp._'Melbournevirus'

TaxID: 1560514

Cluster

View cluster (43 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-98_210-242
PDB
Domain cluster: rep: LacPavin_0818_WC40_scaffold_575784_prodigal-single.1__X__X__00196__D1-108_259-273
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00149.34 best Metallophos 28.9 2.10e-06 99.2% 44.3%
D2 medium residues 99-209
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00149.34 best Metallophos 22.0 2.80e-04 94.6% 25.3%
CATH (42)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3av0A01 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.63 48.0 3.69e-01 93.7% 35.6%
1ii7A01 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.61 52.0 3.95e-01 100.0% 41.0%
3pvsB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 41.0 3.76e-01 97.3% 51.7%
1wx0A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.59 42.0 3.39e-01 100.0% 38.4%
2pk3A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.59 53.0 4.26e-01 100.0% 91.8%
6uczB00 3.20.20.20 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Dihydropteroate synthase-like 0.59 45.0 3.38e-01 93.7% 34.0%
3l5aA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.58 53.0 3.63e-01 100.0% 48.7%
3f4nC00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.58 47.0 3.64e-01 100.0% 39.3%
3n74A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 53.0 4.13e-01 100.0% 95.2%
6y1xB01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.57 51.0 3.97e-01 100.0% 51.4%
1bxkA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 51.0 3.92e-01 100.0% 90.9%
1rh9A00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.56 51.0 3.53e-01 100.0% 37.3%
4p7oB00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.55 49.0 3.52e-01 100.0% 56.6%
1yzyA02 3.40.980.20 Alpha Beta › 3-Layer(aba) Sandwich › Molybdenum Cofactor Biosythetic Enzyme; Chain A › Four-carbon acid sugar kinase, nucleotide binding domain 0.55 48.0 4.07e-01 93.7% 88.2%
4ay7A00 3.20.20.210 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › 0.55 50.0 3.53e-01 100.0% 52.8%
4psrA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.55 48.0 3.39e-01 99.1% 41.1%
3gffA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.54 48.0 3.53e-01 100.0% 62.0%
4nk4F00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 49.0 3.76e-01 100.0% 93.4%
2z5lA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 49.0 3.26e-01 100.0% 36.2%
1itcA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.54 49.0 3.31e-01 100.0% 49.5%
3qleA00 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.54 37.0 3.22e-01 92.8% 43.4%
2cunA02 3.40.50.1260 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate kinase, N-terminal domain 0.54 45.0 3.73e-01 95.5% 50.2%
5vanA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.54 48.0 3.28e-01 100.0% 48.3%
6d2xA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.54 49.0 3.50e-01 100.0% 55.7%
1vcfB00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.54 39.0 2.93e-01 95.5% 28.5%
7toiA01 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.54 49.0 3.92e-01 100.0% 55.3%
4impA03 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 48.0 3.71e-01 100.0% 83.6%
3zm8A02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.53 48.0 3.47e-01 100.0% 49.2%
2qhaA00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.53 47.0 3.41e-01 100.0% 46.7%
3gpgA00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.53 48.0 4.24e-01 100.0% 76.5%
2uv8A04 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 47.0 3.04e-01 100.0% 45.3%
6r62A00 3.20.20.60 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains 0.53 41.0 3.20e-01 100.0% 36.9%
2p10C01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.53 46.0 3.54e-01 100.0% 43.0%
2j62A02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.53 47.0 3.42e-01 100.0% 41.8%
1hdoA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 47.0 3.86e-01 100.0% 79.0%
6xigA01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.52 47.0 3.46e-01 100.0% 43.6%
1jpdX02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.52 38.0 3.15e-01 100.0% 41.5%
6hcdD00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.52 38.0 3.60e-01 93.7% 63.0%
4rgbA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 45.0 3.42e-01 100.0% 93.8%
2ftpA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.51 45.0 3.34e-01 100.0% 37.0%
3canA00 3.80.30.10 Alpha Beta › Alpha-Beta Horseshoe › pyruvate-formate lyase- activating enzyme › pyruvate-formate lyase- activating enzyme 0.50 45.0 4.02e-01 100.0% 84.5%
2c31A01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.50 44.0 3.77e-01 100.0% 76.1%
ECOD (58)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3587179 246.2.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.82 77.0 5.48e-01 100.0% 44.7%
3726470 246.2.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.77 71.0 5.11e-01 100.0% 45.2%
4376563 246.2.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.72 55.0 4.11e-01 100.0% 34.5%
4982610 246.2.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.72 65.0 5.07e-01 100.0% 47.2%
5054928 246.2.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.70 63.0 4.91e-01 100.0% 45.8%
4947548 246.2.1.0 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases 0.67 54.0 4.05e-01 100.0% 36.5%
5023513 246.2.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.66 52.0 3.91e-01 100.0% 35.4%
4202694 2003.1.8.18 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › MurCD/PglD N-terminal domain-like › Pyr_redox 0.66 36.0 3.92e-01 92.8% 63.3%
3291452 7579.1.1.6 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 0.59 52.0 4.05e-01 99.1% 52.6%
2629991 2496.1.1.3 ↗ a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › SiaC 0.59 45.0 4.37e-01 100.0% 71.7%
5084102 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.59 53.0 3.77e-01 100.0% 87.2%
5067065 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.58 50.0 3.82e-01 100.0% 42.0%
4458085 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.58 52.0 3.73e-01 100.0% 40.0%
4033926 2003.1.1.21 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase,DUF1731 0.58 52.0 3.80e-01 100.0% 89.7%
4989163 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.58 52.0 4.03e-01 99.1% 47.1%
5021164 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.58 53.0 3.80e-01 100.0% 41.6%
3725539 2003.1.1.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.57 51.0 4.01e-01 100.0% 97.1%
None — 0.57 52.0 3.60e-01 100.0% 77.6%
4972626 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.57 52.0 3.89e-01 100.0% 45.8%
4450612 2003.1.1.61 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR 0.57 51.0 3.81e-01 100.0% 77.9%
4309938 2003.1.1.61 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR 0.57 51.0 3.74e-01 99.1% 76.9%
4070012 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.57 51.0 3.69e-01 100.0% 41.2%
5049195 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.57 51.0 3.61e-01 100.0% 84.9%
5047183 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.56 51.0 3.82e-01 100.0% 46.7%
4503774 2003.1.1.152 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR, GDP_Man_Dehyd 0.56 50.0 3.72e-01 100.0% 88.1%
3968192 2003.1.1.20 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase 0.56 50.0 3.59e-01 100.0% 88.4%
3450222 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.55 45.0 3.93e-01 96.4% 56.6%
5070796 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.55 42.0 2.96e-01 80.2% 47.0%
4033370 2002.1.1.217 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM,YfkB 0.55 49.0 3.41e-01 100.0% 33.0%
5067096 2007.3.1.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains 0.54 48.0 4.10e-01 96.4% 85.7%
5012375 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.54 49.0 3.87e-01 100.0% 62.6%
3602602 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.54 50.0 3.82e-01 100.0% 53.5%
3263235 300.1.1.8 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › PLDc_2 0.54 42.0 3.52e-01 100.0% 47.7%
5016445 2002.1.1.57 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › URO-D 0.54 49.0 3.66e-01 100.0% 62.1%
4966376 2484.1.1.59 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA 0.54 48.0 3.46e-01 100.0% 47.0%
3695206 2002.1.1.83 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Amidohydro_1 0.54 48.0 3.29e-01 100.0% 42.3%
2543578 2002.1.1.89 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_26 0.54 48.0 3.44e-01 100.0% 53.6%
4954342 2002.1.1.224 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › SPASM 0.53 46.0 3.18e-01 100.0% 29.2%
5035306 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.53 47.0 3.70e-01 100.0% 48.7%
4972403 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.52 41.0 3.40e-01 99.1% 45.2%
4995797 2003.1.1.69 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2 0.52 45.0 3.49e-01 100.0% 93.4%
2126729 2003.1.2.11 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.52 36.0 3.56e-01 91.9% 68.1%
4981908 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.52 47.0 3.28e-01 100.0% 32.6%
3652365 300.1.1.11 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › PLDc_3 0.52 46.0 3.06e-01 100.0% 87.4%
5026547 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.52 46.0 3.59e-01 100.0% 60.2%
4960360 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.51 47.0 3.31e-01 100.0% 34.4%
3996037 2002.1.1.25 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › HMGL-like 0.51 46.0 3.33e-01 100.0% 44.7%
4027539 7574.1.1.7 ↗ a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N 0.51 46.0 3.73e-01 100.0% 74.3%
3987076 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.51 45.0 3.53e-01 100.0% 61.2%
3345296 300.1.1.11 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › PLDc_3 0.51 44.0 3.65e-01 100.0% 53.5%
3306918 7579.1.1.58 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › DUF829 0.51 44.0 3.27e-01 100.0% 70.5%
5075774 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.50 46.0 3.78e-01 100.0% 65.5%
4971687 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.50 46.0 3.01e-01 100.0% 25.4%
3348982 300.1.1.8 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › PLDc_2 0.50 44.0 3.38e-01 100.0% 42.0%
4942944 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.50 46.0 3.21e-01 100.0% 32.9%
4598856 7574.1.1.7 ↗ a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N 0.50 45.0 3.81e-01 100.0% 75.7%
4416801 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.50 45.0 3.15e-01 100.0% 32.0%
4874522 7574.1.1.7 ↗ a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N 0.50 45.0 3.78e-01 100.0% 74.1%