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core_protein

Euk-Vir

Broome_virus

core_protein__YP_003717774__Broome_virus__667093

Identity

Accession:: YP_003717774 ↗
Protein ID:: core_protein
Kingdom:: euk

Quality

84.8 mean pLDDT

Taxonomy

Orthornavirae› Duplornaviricota› Resentoviricetes› Reovirales› Spinareoviridae› Orthoreovirus› Broome_reovirus

TaxID: 667093

Cluster

View cluster (12 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-70_194-282

PDB

Domain cluster: rep: minor_core_protein__YP_004769550__Baboon_orthoreovirus__75888__D1-64_188-280

CATH (5)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3g85A02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.56	34.0	3.71e-01	77.2%	73.0%
2iyvA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.55	44.0	4.23e-01	84.8%	93.3%
1oe4A00	3.40.470.10	Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain	0.52	40.0	3.49e-01	81.6%	99.2%
6de8A01	3.40.50.10860	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1	0.51	38.0	3.95e-01	98.1%	83.0%
3d6iA00	3.40.30.10	Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin	0.50	29.0	3.39e-01	97.5%	80.0%

ECOD (4)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3175188	2004.1.1.65 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › 6PF2K	0.52	46.0	3.77e-01	98.7%	80.3%
3955845	2004.1.1.206 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_31	0.51	47.0	3.98e-01	100.0%	98.1%
4971932	2007.1.5.2 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › CCG	0.51	38.0	4.13e-01	91.1%	91.9%
3994515	2004.1.1.163 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › KTI12	0.51	44.0	4.13e-01	98.1%	94.6%

D2 high residues 75-185

PDB

Domain cluster: rep: VP5__YP_001837098__American_grass_carp_reovirus__465447__D75-176

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF07781.16 best	Reovirus_Mu2	27.6	1.50e-06	94.6%	12.7%

CATH (8)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
8tbxA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.56	45.0	3.61e-01	87.4%	83.6%
1vecA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.55	44.0	3.65e-01	87.4%	85.0%
3berA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.54	43.0	3.52e-01	86.5%	80.0%
5gvrA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.54	43.0	3.43e-01	85.6%	82.5%
1fuuB01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.54	42.0	3.48e-01	86.5%	80.2%
4cbgD02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.54	45.0	3.94e-01	89.2%	89.4%
2z0mA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.52	40.0	3.43e-01	83.8%	85.3%
3iekA02	3.40.50.10890	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.52	45.0	3.91e-01	100.0%	85.7%

ECOD (4)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4370721	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.58	46.0	2.96e-01	87.4%	29.7%
4979530	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.55	43.0	3.58e-01	86.5%	84.2%
None	—		0.52	44.0	3.40e-01	96.4%	90.5%
5000494	2004.1.1.29 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD	0.51	43.0	3.39e-01	91.0%	56.5%

D3 high residues 293-398

PDB

Domain cluster: rep: VP4__YP_009507751__Scophthalmus_maximus_reovirus__994485__D285-391

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF07781.16 best	Reovirus_Mu2	34.0	1.60e-08	99.1%	13.3%

CATH (8)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2qsdA01	3.10.20.10	Alpha Beta › Roll › Ubiquitin-like (UB roll) ›	0.65	35.0	4.30e-01	94.3%	83.6%
4qv2A02	2.40.30.120	Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Positive stranded ssRNA viruses	0.59	40.0	3.87e-01	99.1%	61.0%
1vwxS02	3.10.20.10	Alpha Beta › Roll › Ubiquitin-like (UB roll) ›	0.55	37.0	4.30e-01	100.0%	97.4%
2hfqA00	3.10.510.10	Alpha Beta › Roll › NE1680-like fold › NE1680-like	0.55	34.0	3.76e-01	99.1%	77.6%
3b5mA01	2.30.110.10	Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A	0.55	33.0	3.23e-01	90.6%	52.9%
1h2cA00	2.70.20.20	Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Matrix protein VP40, N-terminal domain	0.53	47.0	4.49e-01	100.0%	97.6%
3bnwB00	2.40.30.30	Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Riboflavin kinase-like	0.52	36.0	3.24e-01	100.0%	49.7%
1i7dA03	2.70.20.10	Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Topoisomerase I, domain 3	0.50	43.0	3.94e-01	95.3%	97.9%

ECOD (13)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3607782	75.1.1.1 ↗	beta barrels › Cyclophilin-like › Cyclophilin-like › Cyclophilin-like › Pro_isomerase	0.63	54.0	4.21e-01	94.3%	98.7%
3808497	75.1.1.1 ↗	beta barrels › Cyclophilin-like › Cyclophilin-like › Cyclophilin-like › Pro_isomerase	0.62	54.0	4.28e-01	96.2%	96.3%
223776	3115.4.1.1 ↗	a+b two layers › GP2-like › Uncharacterized conserved protein Il1583 › Uncharacterized conserved protein Il1583 › DUF1543	0.61	40.0	4.70e-01	100.0%	98.6%
3965010	3115.4.1.1 ↗	a+b two layers › GP2-like › Uncharacterized conserved protein Il1583 › Uncharacterized conserved protein Il1583 › DUF1543	0.59	39.0	4.18e-01	100.0%	77.8%
3743741	220.1.1.86 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like › ZGRF1-like_N	0.58	43.0	4.73e-01	99.1%	96.5%
3782145	220.1.1.86 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like › ZGRF1-like_N	0.56	45.0	4.75e-01	99.1%	96.8%
3411195	11.1.1.538 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › CHRD	0.55	32.0	3.08e-01	91.5%	46.2%
3185550	2487.1.1.0 ↗	a/b three-layered sandwiches › "The ""swivelling"" beta/beta/alpha domains" › "The ""swivelling"" beta/beta/alpha domain" › "The ""swivelling"" beta/beta/alpha domain"	0.55	45.0	4.10e-01	90.6%	99.3%
4263639	323.1.1.0 ↗	a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases	0.55	36.0	2.99e-01	92.5%	37.4%
3391889	11.1.6.1 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › UPA domain › UPA	0.54	40.0	3.78e-01	79.2%	100.0%
3171382	220.1.1.86 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like › ZGRF1-like_N	0.53	42.0	4.56e-01	95.3%	98.9%
3436556	220.1.1.86 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like › ZGRF1-like_N	0.53	36.0	4.17e-01	91.5%	100.0%
3315951	220.1.1.86 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like › ZGRF1-like_N	0.51	36.0	4.12e-01	92.5%	100.0%

D4 high residues 602-736

PDB

Domain cluster: rep: muA__YP_009020574__Reptilian_orthoreovirus__226613__D604-737

D5 medium residues 399-451_512-564

PDB

Domain cluster: rep: muA__YP_009020574__Reptilian_orthoreovirus__226613__D404-449_512-560

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF07781.16 best	Reovirus_Mu2	26.4	3.30e-06	49.1%	6.3%

D6 medium residues 452-511_565-601

PDB

Domain cluster: rep: muA__YP_009020574__Reptilian_orthoreovirus__226613__D450-511_561-594