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coronavirus_nsp12

Euk-Vir

Infectious_bronchitis_virus

coronavirus_nsp12__NP_740632__Infectious_bronchitis_virus__11120

Identity

Accession:
NP_740632 ↗
Protein ID:
coronavirus_nsp12
Kingdom:
euk

Quality

94.3 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Pisoniviricetes› Nidovirales› Coronaviridae› Gammacoronavirus› Infectious_bronchitis_virus

TaxID: 11120

Cluster

View cluster (23 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-60
PDB
Domain cluster: rep: putative_coronavirus_nsp12__NP_839968__Porcine_epidemic_diarrhea_virus__28295__D1-51
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF19219.6 best CoV_NSP15_N 86.3 1.70e-24 100.0% 96.7%
D2 high residues 66-177
PDB
Domain cluster: rep: NSP15__YP_001941188__Turkey_coronavirus__11152__D65-176
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF19216.6 best CoV_NSP15_M 111.3 4.70e-32 98.2% 94.9%
D3 high residues 198-335
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF19215.6 best CoV_NSP15_C 145.9 1.30e-42 100.0% 87.7%
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3tw8A01 3.30.450.200 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Longin module 0.63 35.0 3.52e-01 89.9% 53.6%
3itwA02 3.30.720.110 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › 0.59 26.0 3.74e-01 75.4% 96.4%
3u97A00 3.10.450.530 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 0.58 32.0 4.03e-01 87.0% 93.5%
4qunA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.56 47.0 3.75e-01 92.0% 76.7%
3e5dA00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.56 31.0 3.24e-01 74.6% 56.8%
2xepB01 3.10.450.280 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.55 30.0 3.30e-01 100.0% 63.2%
2rbbA00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.54 28.0 2.93e-01 73.9% 51.9%
4ikcA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.53 44.0 3.58e-01 91.3% 76.6%
1zc0A00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.52 43.0 3.48e-01 89.9% 73.4%
2nlkA02 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.51 42.0 3.44e-01 88.4% 77.3%
4r80A00 3.10.450.630 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 24.0 3.04e-01 70.3% 76.3%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2755815 372.2.1.2 ↗ a+b complex topology › RNase A-like › EndoU-like › EndoU-like › CoV_NSP15_C 0.94 90.0 8.50e-01 100.0% 86.1%
2623965 372.2.1.0 ↗ a+b complex topology › RNase A-like › EndoU-like › EndoU-like 0.92 78.0 7.34e-01 87.7% 75.3%
3897033 372.2.1.1 ↗ a+b complex topology › RNase A-like › EndoU-like › EndoU-like › XendoU 0.84 79.0 6.09e-01 100.0% 73.7%
3481114 372.2.1.0 ↗ a+b complex topology › RNase A-like › EndoU-like › EndoU-like 0.83 78.0 6.16e-01 100.0% 77.1%
3480203 372.2.1.1 ↗ a+b complex topology › RNase A-like › EndoU-like › EndoU-like › XendoU 0.82 70.0 6.62e-01 89.1% 85.5%
3212655 372.2.1.1 ↗ a+b complex topology › RNase A-like › EndoU-like › EndoU-like › XendoU 0.81 76.0 6.07e-01 100.0% 77.5%
3510572 372.2.1.1 ↗ a+b complex topology › RNase A-like › EndoU-like › EndoU-like › XendoU 0.81 76.0 5.96e-01 100.0% 78.1%
3512494 372.2.1.1 ↗ a+b complex topology › RNase A-like › EndoU-like › EndoU-like › XendoU 0.80 75.0 5.97e-01 100.0% 77.8%
3940407 372.2.1.1 ↗ a+b complex topology › RNase A-like › EndoU-like › EndoU-like › XendoU 0.80 75.0 5.62e-01 100.0% 65.9%
3513367 372.2.1.1 ↗ a+b complex topology › RNase A-like › EndoU-like › EndoU-like › XendoU 0.80 75.0 5.78e-01 100.0% 71.9%
3505573 372.2.1.1 ↗ a+b complex topology › RNase A-like › EndoU-like › EndoU-like › XendoU 0.78 73.0 5.79e-01 100.0% 77.0%
5053654 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.66 33.0 3.57e-01 89.9% 55.0%
4945086 239.5.1.0 ↗ beta barrels › Ribosomal protein L25-like › 40S ribosomal protein S3A N-terminal domain › 40S ribosomal protein S3A N-terminal domain 0.60 28.0 3.90e-01 85.5% 88.6%
3973892 3994.1.1.2 ↗ a+b two layers › C-P lyase subunit PhnG › C-P lyase subunit PhnG › C-P lyase subunit PhnG › PhnG 0.53 26.0 2.80e-01 84.1% 52.2%
3397960 2007.2.3.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase 0.53 44.0 3.53e-01 91.3% 82.8%
3533688 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.51 25.0 3.17e-01 82.6% 81.3%
3611339 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.50 27.0 3.25e-01 93.5% 81.2%
3987561 6082.1.1.0 ↗ beta sandwiches › N-terminal domain of BT_2081-like › N-terminal domain of BT_2081-like › N-terminal domain of BT_2081-like 0.50 26.0 3.29e-01 84.8% 85.0%