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deoxyguanosine_kinase_2
Euk-VirAnguillid_herpesvirus_1
deoxyguanosine_kinase_2__YP_003358262__Anguillid_herpesvirus_1__150286
Identity
- Accession:
- YP_003358262 ↗
- Protein ID:
- deoxyguanosine_kinase_2
- Kingdom:
- euk
Quality
84.3
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Alloherpesviridae›
Cyvirus›
Anguillid_herpesvirus_1
TaxID: 150286
Cluster
View cluster (88 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-131_233-253
Domain cluster:
rep: thymidine_kinase__YP_009118411__Equid_gammaherpesvirus_5__10371__D300-425_605-623
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01712.26 best | dNK | 43.3 | 5.20e-11 | 88.2% | 45.8% |
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1p5zB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.70 | 64.0 | 5.41e-01 | 94.7% | 100.0% |
| 6wilA02 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.65 | 29.0 | 3.82e-01 | 80.9% | 75.0% |
| 1osnC00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.64 | 59.0 | 4.62e-01 | 99.3% | 94.2% |
| 1ly1A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.62 | 43.0 | 4.31e-01 | 96.7% | 69.7% |
| 2plrA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 56.0 | 5.00e-01 | 98.7% | 100.0% |
| 1gtvA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 53.0 | 4.77e-01 | 93.4% | 100.0% |
| 1zm7B00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.60 | 55.0 | 4.95e-01 | 95.4% | 93.4% |
| 3v9pB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.60 | 53.0 | 4.84e-01 | 95.4% | 100.0% |
| 4lizA00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.60 | 38.0 | 3.94e-01 | 83.6% | 68.1% |
| 1hqz800 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.59 | 36.0 | 3.87e-01 | 80.3% | 68.2% |
| 2bbwA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 49.0 | 4.32e-01 | 95.4% | 96.4% |
| 6c6bB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 51.0 | 4.61e-01 | 100.0% | 94.0% |
| 1kagA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.53 | 46.0 | 4.56e-01 | 92.1% | 99.4% |
| 2ze6A01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.53 | 40.0 | 4.38e-01 | 94.1% | 95.2% |
| 2rqlA00 | 3.30.160.100 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like | 0.53 | 24.0 | 2.98e-01 | 71.7% | 67.4% |
| 6fwrA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 48.0 | 4.34e-01 | 98.7% | 99.5% |
| 1t3yA00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.51 | 36.0 | 3.82e-01 | 78.3% | 82.4% |
| 2kjqA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.51 | 32.0 | 3.50e-01 | 83.6% | 75.4% |
| 1o98A02 | 3.40.720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A | 0.51 | 44.0 | 3.66e-01 | 95.4% | 99.3% |
| 3igzB01 | 3.40.720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A | 0.50 | 44.0 | 3.54e-01 | 96.1% | 84.9% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3965422 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.72 | 45.0 | 5.61e-01 | 84.2% | 100.0% |
| 3735545 | 2004.1.1.202 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_28 | 0.69 | 65.0 | 5.72e-01 | 99.3% | 99.5% |
| 3753842 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.67 | 62.0 | 5.34e-01 | 97.4% | 95.1% |
| 3256346 | 224.1.1.1 ↗ | a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Cofilin_ADF | 0.64 | 39.0 | 4.17e-01 | 80.3% | 69.2% |
| 3595484 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.64 | 42.0 | 3.87e-01 | 98.7% | 52.6% |
| 3590072 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.63 | 58.0 | 4.95e-01 | 98.0% | 93.6% |
| 3701198 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.61 | 56.0 | 4.65e-01 | 99.3% | 97.3% |
| 315491 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.60 | 55.0 | 4.96e-01 | 95.4% | 93.4% |
| 4575832 | 2004.1.1.59 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CoaE | 0.60 | 54.0 | 4.93e-01 | 96.1% | 100.0% |
| 3612792 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.58 | 51.0 | 4.45e-01 | 97.4% | 99.1% |
| 5016561 | 3003.1.1.0 ↗ | a+b complex topology › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) | 0.57 | 25.0 | 3.22e-01 | 82.9% | 70.6% |
| 2167612 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.56 | 47.0 | 4.88e-01 | 93.4% | 96.4% |
| 3712896 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.54 | 47.0 | 3.74e-01 | 96.7% | 69.5% |
| 3246286 | 7579.1.1.3 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S9 | 0.53 | 42.0 | 3.38e-01 | 82.9% | 93.8% |
| 5001411 | 7515.1.1.6 ↗ | a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Phosphodiest | 0.53 | 47.0 | 3.52e-01 | 98.0% | 66.8% |
| 4984288 | 2004.1.1.85 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ArsA_ATPase | 0.52 | 46.0 | 3.62e-01 | 97.4% | 94.0% |
| 5036660 | 7515.1.1.6 ↗ | a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Phosphodiest | 0.52 | 46.0 | 3.52e-01 | 100.0% | 90.5% |
| 3813073 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.52 | 46.0 | 4.34e-01 | 97.4% | 98.9% |
| 4393604 | 224.1.1.1 ↗ | a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Cofilin_ADF | 0.52 | 36.0 | 3.72e-01 | 80.9% | 73.0% |
| 5063036 | 7515.1.1.6 ↗ | a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Phosphodiest | 0.52 | 46.0 | 3.28e-01 | 98.7% | 97.8% |
| 3397542 | 7515.1.1.0 ↗ | a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like | 0.52 | 45.0 | 3.48e-01 | 96.1% | 82.0% |
| 4932362 | 4244.1.1.5 ↗ | a/b three-layered sandwiches › EreA/ChaN-like › EreA/ChaN-like › EreA/ChaN-like › TraB_PrgY_gumN | 0.51 | 41.0 | 3.56e-01 | 84.2% | 75.7% |
| 3707692 | 2004.1.1.19 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras | 0.51 | 46.0 | 4.36e-01 | 99.3% | 92.3% |
| 4012707 | 224.1.1.0 ↗ | a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like | 0.51 | 36.0 | 3.67e-01 | 81.6% | 73.2% |
| 3593921 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.51 | 46.0 | 4.34e-01 | 99.3% | 91.9% |
| 3901141 | 2004.1.1.54 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Septin | 0.51 | 45.0 | 3.51e-01 | 98.0% | 73.9% |
| 4359972 | 7515.1.1.19 ↗ | a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Sulfatase, Phosphodiest | 0.50 | 44.0 | 3.53e-01 | 96.7% | 81.0% |
| 3593400 | 2002.1.1.0 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels | 0.50 | 40.0 | 3.23e-01 | 85.5% | 94.8% |
D2
medium
residues 132-232
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01712.26 best | dNK | 46.2 | 6.70e-12 | 96.0% | 28.6% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2jaqA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.77 | 69.0 | 5.53e-01 | 100.0% | 51.3% |
| 2h92A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.62 | 56.0 | 4.37e-01 | 100.0% | 78.7% |
| 3juwA00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.59 | 37.0 | 3.18e-01 | 71.3% | 38.3% |
| 2x9qB00 | 3.40.50.11710 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cyclodipeptide synthase | 0.52 | 40.0 | 3.12e-01 | 82.2% | 55.9% |
| 5ywwA01 | 3.40.50.1010 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease | 0.52 | 35.0 | 3.36e-01 | 86.1% | 60.0% |
| 6vsxA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 31.0 | 2.66e-01 | 79.2% | 39.0% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3314216 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.84 | 79.0 | 5.59e-01 | 100.0% | 51.4% |
| 4435067 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.82 | 77.0 | 5.58e-01 | 100.0% | 43.5% |
| 3273940 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.78 | 71.0 | 5.47e-01 | 100.0% | 46.7% |
| 4032154 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.77 | 69.0 | 5.44e-01 | 100.0% | 48.5% |
| 4936538 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.71 | 66.0 | 4.93e-01 | 100.0% | 44.3% |
| 3825436 | 2004.1.1.41 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ADK | 0.64 | 57.0 | 5.27e-01 | 99.0% | 91.5% |
| 4423734 | 2004.1.1.106 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › RapZ-like_N | 0.63 | 51.0 | 4.33e-01 | 86.1% | 69.7% |
| 4285153 | 2004.1.1.80 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Cytidylate_kin | 0.63 | 57.0 | 4.39e-01 | 100.0% | 76.0% |
| 5010661 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.60 | 54.0 | 4.81e-01 | 100.0% | 77.1% |
| 3518548 | 2004.1.1.80 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Cytidylate_kin | 0.60 | 51.0 | 4.29e-01 | 93.1% | 65.7% |
| 4957006 | 2004.1.1.191 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_17 | 0.58 | 52.0 | 4.27e-01 | 100.0% | 61.9% |
| 3282741 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.57 | 49.0 | 4.07e-01 | 91.1% | 64.7% |
| 4012661 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.53 | 45.0 | 3.68e-01 | 100.0% | 66.2% |
| 3261718 | 2004.1.1.33 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C,RecQ_Zn_bind | 0.51 | 36.0 | 2.89e-01 | 75.2% | 99.1% |
| 3277906 | 2004.1.1.239 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SLFN-g3_helicase | 0.50 | 37.0 | 3.04e-01 | 78.2% | 82.0% |