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deoxyribonuclease
Euk-VirFruit_bat_alphaherpesvirus_1
deoxyribonuclease__YP_009042074__Fruit_bat_alphaherpesvirus_1__1343901
Identity
- Accession:
- YP_009042074 ↗
- Protein ID:
- deoxyribonuclease
- Kingdom:
- euk
Quality
70.2
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Simplexvirus›
Pteropodid_alphaherpesvirus_1
TaxID: 1343901
Cluster
View cluster (76 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 173-249
Domain cluster:
representative
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3hwcA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 52.0 | 3.87e-01 | 84.4% | 41.9% |
| 1c3cA01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.61 | 53.0 | 4.98e-01 | 92.2% | 91.2% |
| 3h0dB02 | 1.10.1200.150 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Transcriptional repressor of class III stress genes, C-terminal domain | 0.60 | 45.0 | 4.43e-01 | 84.4% | 76.5% |
| 3iieB03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.59 | 41.0 | 4.05e-01 | 84.4% | 67.1% |
| 4zqeA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.58 | 41.0 | 3.92e-01 | 98.7% | 61.5% |
| 3ocjA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.58 | 49.0 | 3.36e-01 | 98.7% | 74.3% |
| 3dfzA02 | 1.10.8.610 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › SirC, precorrin-2 dehydrogenase, C-terminal helical domain-like | 0.56 | 42.0 | 4.35e-01 | 90.9% | 85.1% |
| 3fwbA01 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.56 | 39.0 | 3.82e-01 | 87.0% | 68.3% |
| 1ga3A00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.54 | 37.0 | 3.29e-01 | 71.4% | 97.3% |
| 4lvnA00 | 3.40.50.200 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidase S8/S53 domain | 0.54 | 46.0 | 3.09e-01 | 100.0% | 89.6% |
| 3dzaA01 | 1.20.120.1940 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YfdX protein domain | 0.53 | 39.0 | 3.43e-01 | 83.1% | 51.3% |
| 1e6dM01 | 1.20.85.10 | Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like | 0.52 | 38.0 | 3.15e-01 | 77.9% | 69.9% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 118932 | 4952.1.1.0 ↗ | alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like | 0.61 | 53.0 | 4.98e-01 | 92.2% | 91.2% |
| 4208818 | 4952.1.1.0 ↗ | alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like | 0.61 | 51.0 | 4.96e-01 | 89.6% | 96.5% |
| 4682059 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.60 | 43.0 | 4.13e-01 | 97.4% | 64.5% |
| 3917223 | 174.1.1.73 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Solute_trans_a | 0.58 | 43.0 | 3.22e-01 | 80.5% | 69.3% |
| 3622554 | 5050.1.1.6 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › OATP | 0.57 | 47.0 | 3.33e-01 | 94.8% | 83.0% |
| 3782635 | 3837.1.1.1 ↗ | alpha bundles › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › DUF6847 | 0.57 | 40.0 | 3.19e-01 | 71.4% | 94.2% |
| 4037328 | 161.1.1.1 ↗ | alpha complex topology › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › SecA_SW | 0.57 | 42.0 | 3.16e-01 | 79.2% | 73.3% |
| 5038778 | 5054.1.1.6 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH | 0.56 | 42.0 | 3.58e-01 | 83.1% | 70.4% |
| 4573573 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.54 | 39.0 | 3.76e-01 | 98.7% | 65.6% |
| 3925885 | 311.1.1.0 ↗ | a+b three layers › Phoshotransferase/anion transport protein › Phoshotransferase/anion transport protein › Phoshotransferase/anion transport protein | 0.53 | 46.0 | 3.43e-01 | 100.0% | 62.4% |
| 5057377 | 5054.1.1.6 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH | 0.53 | 41.0 | 3.61e-01 | 84.4% | 75.7% |
| 3671034 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.51 | 38.0 | 3.74e-01 | 81.8% | 80.0% |
| 3735003 | 109.4.1.198 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 | 0.50 | 44.0 | 2.77e-01 | 100.0% | 96.9% |
D2
medium
residues 250-321_347-397
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01771.24 best | Viral_alk_exo | 122.8 | 2.20e-35 | 100.0% | 27.6% |
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3syyA00 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.74 | 61.0 | 5.18e-01 | 95.9% | 55.2% |
| 3sm4A00 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.68 | 63.0 | 5.11e-01 | 100.0% | 54.2% |
| 3hy3A00 | 3.40.50.10420 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NagB/RpiA/CoA transferase-like | 0.50 | 37.0 | 3.25e-01 | 78.0% | 100.0% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3647811 | 2008.1.1.50 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YqaJ | 0.72 | 68.0 | 5.24e-01 | 100.0% | 49.6% |
| 3262255 | 2008.1.1.50 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YqaJ | 0.72 | 68.0 | 5.92e-01 | 100.0% | 72.0% |
| 424674 | 2008.1.1.50 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YqaJ | 0.70 | 64.0 | 5.12e-01 | 100.0% | 52.4% |
| 2491448 | 2008.1.1.50 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YqaJ | 0.66 | 62.0 | 4.24e-01 | 100.0% | 41.8% |
| 3959053 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.57 | 48.0 | 4.21e-01 | 90.2% | 84.3% |
| 3950933 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.56 | 47.0 | 3.66e-01 | 89.4% | 73.6% |
D3
medium
residues 398-460
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01771.24 best | Viral_alk_exo | 55.1 | 8.10e-15 | 100.0% | 13.2% |
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2xauA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.63 | 51.0 | 3.50e-01 | 92.1% | 54.7% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 182718 | 2008.1.1.2 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Viral_alk_exo | 0.94 | 86.0 | 5.01e-01 | 100.0% | 13.9% |
| 3540823 | 2484.1.1.175 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FGGY_N+FGGY_C | 0.56 | 43.0 | 2.56e-01 | 84.1% | 37.7% |
| 3984005 | 129.1.1.51 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › ADH_zinc_N | 0.52 | 39.0 | 2.61e-01 | 100.0% | 18.3% |
| 4963199 | 219.1.1.13 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core | 0.51 | 37.0 | 2.79e-01 | 77.8% | 67.9% |
| 3646879 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.50 | 46.0 | 3.37e-01 | 100.0% | 50.0% |
D4
medium
residues 476-572_590-638
Domain cluster:
rep: deoxyribonuclease__YP_010087590__Cervid_alphaherpesvirus_3__2115790__D246-278_337-366_406-456
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01771.24 best | Viral_alk_exo | 95.3 | 5.10e-27 | 100.0% | 30.8% |