deoxyribonuclease

Euk-Vir

Human_alphaherpesvirus_1

deoxyribonuclease__YP_009137086__Human_alphaherpesvirus_1__10298

Identity

70.4 mean pLDDT

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Simplexvirus› Human_alphaherpesvirus_1

TaxID: 10298

View cluster (76 members)

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high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 139-267

PDB

Domain cluster: rep: deoxyribonuclease__YP_009230142__Leporid_alphaherpesvirus_4__481315__D113-231

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01771.24 best	Viral_alk_exo	67.5	1.30e-18	99.2%	15.8%

D2 medium residues 300-356

PDB

D3 medium residues 357-507_527-540

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01771.24 best	Viral_alk_exo	187.8	4.40e-55	92.1%	31.7%

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5jpnB02	2.20.130.20	Mainly Beta › Single Sheet › S-adenosyl-L-methionine-dependent methyltransferases ›	0.59	24.0	3.61e-01	81.8%	98.3%

ECOD (2)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
182718	2008.1.1.2 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Viral_alk_exo	0.86	82.0	5.80e-01	100.0%	39.6%
1391879	11.1.1.6 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › A2M	0.50	22.0	2.90e-01	83.6%	72.6%

D4 medium residues 508-526_541-602

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01771.24 best	Viral_alk_exo	41.0	1.50e-10	100.0%	19.3%

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2eefA01	2.60.40.2440	Mainly Beta › Sandwich › Immunoglobulin-like › Carbohydrate binding type-21 domain	0.52	28.0	2.47e-01	80.2%	29.9%
7cm3A01	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.51	39.0	3.17e-01	82.7%	70.7%

ECOD (4)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3939937	5052.1.1.1 ↗	alpha complex topology › Proton glutamate symport protein › Proton glutamate symport protein › Proton glutamate symport protein › SDF	0.74	35.0	2.13e-01	85.2%	8.6%
2666180	2485.3.1.4 ↗	a+b three layers › Thioredoxin-like › Major capsid protein gp5 › Major capsid protein gp5 › Phage_cap_P2	0.70	30.0	2.19e-01	82.7%	17.2%
3665681	2004.1.1.26 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin	0.54	42.0	2.62e-01	82.7%	78.1%
3589383	885.1.1.1 ↗	a+b complex topology › Transcription factor NusA, N-terminal domain › Transcription factor NusA, N-terminal domain › Transcription factor NusA, N-terminal domain › NusA_N	0.51	43.0	3.75e-01	92.6%	82.4%