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deoxyribonuclease

Euk-Vir

Human_betaherpesvirus_7

deoxyribonuclease__YP_073810__Human_betaherpesvirus_7__10372

Identity

Accession:: YP_073810 ↗
Protein ID:: deoxyribonuclease
Kingdom:: euk

Quality

90.1 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Roseolovirus› Human_betaherpesvirus_7

TaxID: 10372

Cluster

View cluster (76 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-130

PDB

Domain cluster: rep: GP98__YP_007417864__Caviid_betaherpesvirus_2__33706__D55-187

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01771.24 best	Viral_alk_exo	54.3	1.30e-14	94.4%	23.0%

CATH (16)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2w45A01	1.20.120.860	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Herpesvirus alkaline exonuclease, N-terminal domain	0.80	68.0	7.05e-01	99.2%	96.6%
3fhdA01	1.20.120.860	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Herpesvirus alkaline exonuclease, N-terminal domain	0.75	65.0	6.37e-01	99.2%	85.3%
8gr7A01	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.59	42.0	3.22e-01	74.6%	48.3%
3cxbA03	1.10.1740.30	Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain	0.57	34.0	4.11e-01	74.6%	92.6%
4x5mA00	1.20.1280.290	Mainly Alpha › Up-down Bundle › Monooxygenase ›	0.56	31.0	3.58e-01	100.0%	75.6%
1cy5A00	1.10.533.10	Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas	0.55	34.0	3.90e-01	73.8%	85.9%
2q14B01	1.10.3210.10	Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432	0.54	38.0	3.19e-01	73.0%	65.7%
3awmA00	1.10.630.10	Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450	0.54	48.0	3.41e-01	100.0%	69.8%
2l6jA00	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.52	33.0	3.53e-01	92.9%	71.2%
4akgA16	1.10.8.720	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Region D6 of dynein motor	0.52	44.0	4.05e-01	92.9%	77.6%
2ot4A03	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.51	34.0	3.66e-01	70.6%	80.4%
6f7hA00	1.20.1080.10	Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein.	0.51	42.0	3.38e-01	90.5%	82.1%
5dkoA02	1.10.3900.10	Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like	0.50	44.0	4.04e-01	97.6%	95.2%
2mqaA00	1.10.274.60	Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain	0.50	35.0	3.55e-01	70.6%	95.2%
2wzkA03	1.20.1310.10	Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats	0.50	30.0	3.17e-01	100.0%	64.5%
3ce9A02	1.20.1090.10	Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain	0.50	36.0	3.14e-01	74.6%	47.9%

ECOD (21)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3519620	190.1.1.0 ↗	alpha arrays › HMG-box-like › HMG-box › HMG-box	0.67	36.0	3.87e-01	95.2%	60.0%
3693124	190.1.1.1 ↗	alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box	0.65	36.0	4.19e-01	94.4%	75.6%
4057021	605.4.1.20 ↗	alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › DUF6092	0.65	45.0	5.15e-01	85.7%	98.9%
4673714	141.1.1.8 ↗	alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_syn_C_2	0.60	43.0	3.14e-01	73.8%	43.0%
3238246	150.1.1.0 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin	0.59	41.0	4.39e-01	74.6%	82.7%
3411834	150.1.1.57 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › NEPRO_N	0.56	40.0	3.49e-01	74.6%	99.0%
4979197	5059.1.1.1 ↗	alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA	0.55	45.0	3.51e-01	88.9%	77.6%
3829049	174.1.1.90 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › RPW8	0.54	38.0	3.86e-01	73.0%	76.0%
3203823	206.1.1.82 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF7580	0.54	48.0	3.62e-01	100.0%	42.5%
4972788	601.2.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes	0.53	39.0	4.19e-01	91.3%	90.0%
3186741	5050.1.1.0 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter	0.52	39.0	3.18e-01	77.8%	77.0%
3900656	3831.1.1.6 ↗	alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › POF1B_HlH	0.52	30.0	3.52e-01	100.0%	82.4%
5035458	632.1.1.3 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid	0.52	37.0	4.09e-01	73.0%	96.8%
5014274	1075.1.1.0 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain	0.52	41.0	3.55e-01	84.9%	97.0%
4982608	1079.1.1.0 ↗	alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA	0.51	38.0	3.18e-01	77.0%	90.7%
3633559	5050.1.1.9 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1	0.51	38.0	3.16e-01	77.8%	82.7%
4578804	160.1.1.4 ↗	alpha superhelices › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › ATP-synt_VA_C	0.51	37.0	3.82e-01	84.1%	80.9%
3713234	3187.1.1.0 ↗	alpha bundles › Microtubule-Binding Domain of Flagellar Dynein › Microtubule-Binding Domain of Flagellar Dynein › Microtubule-Binding Domain of Flagellar Dynein	0.51	37.0	3.30e-01	74.6%	66.5%
3584767	5050.1.1.0 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter	0.50	37.0	3.03e-01	77.0%	80.0%
4499455	633.5.1.1 ↗	alpha bundles › Bromodomain-like › LemA-like › LemA-like › LemA	0.50	36.0	3.37e-01	77.0%	58.7%
3264408	3745.1.1.1 ↗	alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex	0.50	43.0	3.24e-01	93.7%	81.6%

D2 medium residues 164-193_211-223_322-427_448-474

PDB

Domain cluster: rep: Exonuclease__YP_214099__Murid_betaherpesvirus_1__10366__D221-282_429-473_511-556

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01771.24 best	Viral_alk_exo	95.2	5.30e-27	77.8%	20.6%