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deoxyuridine_triphosphatase

Euk-Vir

Equid_alphaherpesvirus_4

deoxyuridine_triphosphatase__NP_045226__Equid_alphaherpesvirus_4__10331

Identity

Accession:
NP_045226 ↗
Protein ID:
deoxyuridine_triphosphatase
Kingdom:
euk

Quality

80.3 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Varicellovirus› Equid_alphaherpesvirus_4

TaxID: 10331

Cluster

View cluster (50 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 11-141_286-310
PDB
Domain cluster: rep: hypothetical_protein_RHVP.11__YP_004207851__Cricetid_gammaherpesvirus_2__1605972__D11-122
CATH (46)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1dunA00 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.80 54.0 6.13e-01 84.0% 88.3%
3ecyA00 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.78 52.0 5.94e-01 84.0% 88.2%
2d4lA01 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.78 51.0 6.08e-01 82.7% 96.2%
4ao5B01 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.78 56.0 6.38e-01 84.0% 97.4%
1sixA00 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.77 55.0 5.65e-01 84.0% 75.2%
3h6xB00 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.74 56.0 6.17e-01 84.0% 94.6%
1euwA00 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.72 55.0 5.84e-01 84.0% 89.0%
2bsyA01 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.72 64.0 6.61e-01 99.4% 98.6%
3t64A01 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.71 60.0 6.34e-01 96.2% 99.3%
2bsyA02 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.71 46.0 5.53e-01 84.0% 100.0%
1tulA00 2.70.40.20 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Baculovirus telokin-like protein 20 0.70 44.0 5.23e-01 79.5% 95.1%
3zf0A00 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.68 55.0 5.69e-01 84.0% 89.9%
2yzjA01 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.64 52.0 5.48e-01 84.0% 93.6%
1pkhB00 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.63 51.0 4.90e-01 84.0% 90.3%
6sl4A00 2.60.40.710 Mainly Beta › Sandwich › Immunoglobulin-like › Endoglucanase-like 0.63 46.0 4.72e-01 93.6% 78.7%
2r9qC01 2.70.40.10 Mainly Beta › Distorted Sandwich › Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A › Deoxyuridine triphosphatase (dUTPase) 0.62 50.0 4.96e-01 84.0% 93.3%
4b97A00 2.60.40.710 Mainly Beta › Sandwich › Immunoglobulin-like › Endoglucanase-like 0.61 45.0 4.64e-01 94.2% 79.5%
4ncdA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 42.0 4.68e-01 93.6% 92.4%
4g5aA00 2.60.40.3080 Mainly Beta › Sandwich › Immunoglobulin-like › 0.59 31.0 3.73e-01 85.9% 75.8%
4aw7A03 2.60.120.1200 Mainly Beta › Sandwich › Jelly Rolls › 0.59 39.0 4.35e-01 92.3% 86.1%
4zrxA02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.58 37.0 4.28e-01 91.7% 92.4%
2id4A02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.58 42.0 4.42e-01 92.3% 84.1%
3obaA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 41.0 4.51e-01 94.2% 92.9%
1od3A00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.56 40.0 4.36e-01 92.3% 87.8%
2edmA00 2.60.40.2770 Mainly Beta › Sandwich › Immunoglobulin-like › WSSV envelope protein-like 0.55 42.0 4.22e-01 80.1% 95.7%
6se8A04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 35.0 4.10e-01 94.2% 92.6%
2cdoA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.55 42.0 4.43e-01 94.2% 90.6%
3h8uA00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.55 35.0 3.85e-01 94.2% 80.3%
3am2A02 2.60.120.1050 Mainly Beta › Sandwich › Jelly Rolls › 0.54 36.0 4.08e-01 92.9% 89.7%
2vecA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.54 34.0 4.03e-01 78.8% 93.2%
1f15B00 2.60.120.530 Mainly Beta › Sandwich › Jelly Rolls › Cucumovirus coat protein, subunit A 0.54 43.0 4.05e-01 93.6% 68.4%
4lplA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.54 39.0 4.14e-01 96.8% 83.8%
2w47A00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.53 40.0 4.28e-01 92.3% 90.4%
1gnyA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.53 44.0 4.44e-01 93.6% 90.2%
6tfjA01 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.53 36.0 4.12e-01 89.1% 95.7%
4qawH03 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.52 39.0 4.20e-01 92.3% 91.0%
3hlzB01 3.40.1000.10 Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › Mog1/PsbP, alpha/beta/alpha sandwich 0.52 33.0 3.48e-01 84.0% 70.0%
2wq4A01 2.60.120.760 Mainly Beta › Sandwich › Jelly Rolls › 0.52 38.0 4.06e-01 93.6% 90.7%
1hn0A01 2.60.120.430 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding lectin 0.51 43.0 4.09e-01 93.6% 77.7%
3kq4B04 2.60.120.290 Mainly Beta › Sandwich › Jelly Rolls › Spermadhesin, CUB domain 0.51 32.0 3.64e-01 92.3% 86.5%
4yarA02 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.51 31.0 3.43e-01 80.8% 75.6%
2j1vA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.51 40.0 4.16e-01 92.3% 91.5%
4wz9A01 2.60.40.1730 Mainly Beta › Sandwich › Immunoglobulin-like › tricorn interacting facor f3 domain 0.50 42.0 3.83e-01 96.8% 65.9%
2wnoA01 2.60.120.290 Mainly Beta › Sandwich › Jelly Rolls › Spermadhesin, CUB domain 0.50 32.0 3.67e-01 91.7% 88.5%
2ed6A01 2.60.40.2770 Mainly Beta › Sandwich › Immunoglobulin-like › WSSV envelope protein-like 0.50 40.0 4.06e-01 84.0% 98.7%
3nngA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.50 40.0 4.11e-01 92.3% 88.2%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
367299 70.2.1.0 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like 0.85 55.0 6.44e-01 84.0% 91.1%
162469 70.2.1.1 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like › dUTPase 0.78 51.0 5.88e-01 82.7% 89.5%
27204 70.2.1.1 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like › dUTPase 0.77 56.0 6.00e-01 84.0% 85.8%
4876557 70.2.1.1 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like › dUTPase 0.77 55.0 5.84e-01 84.0% 82.1%
5025697 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.63 40.0 4.54e-01 92.3% 84.3%
5004407 70.2.1.6 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like › DUF22 0.63 39.0 4.30e-01 73.7% 76.0%
None — 0.63 51.0 4.94e-01 84.0% 82.9%
5002855 70.2.1.5 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like › DCD 0.62 50.0 4.87e-01 84.0% 83.2%
4080854 70.2.1.5 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like › DCD 0.62 51.0 5.26e-01 98.1% 89.3%
4266103 10.32.1.4 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › EMP24_GP25L 0.61 39.0 4.26e-01 92.3% 76.9%
4944751 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.60 40.0 4.49e-01 91.7% 87.5%
5041352 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.60 38.0 4.15e-01 92.3% 77.6%
5025621 70.2.1.5 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like › DCD 0.60 49.0 4.94e-01 98.7% 84.4%
4407112 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.59 37.0 4.36e-01 92.9% 92.4%
1247251 70.2.1.3 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like › DCD_N 0.59 50.0 4.92e-01 89.7% 94.6%
3742620 11.1.5.7 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › Adap_comp_sub 0.58 38.0 4.35e-01 91.7% 90.4%
3939502 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.58 38.0 4.28e-01 93.6% 89.6%
3640397 10.41.1.1 ↗ beta sandwiches › jelly-roll › Protein Hikeshi jelly-roll domain › Protein Hikeshi jelly-roll domain › Hikeshi-like_N 0.57 45.0 4.77e-01 82.7% 93.6%
3423605 10.12.1.27 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › Cupin_3 0.57 28.0 3.33e-01 95.5% 66.7%
1221508 11.1.1.14 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Glyco_hydro_2 0.57 41.0 4.52e-01 94.2% 92.9%
5073212 70.2.1.5 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like › DCD 0.57 53.0 5.19e-01 98.7% 95.8%
4269280 70.2.1.5 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like › DCD 0.56 52.0 5.05e-01 98.7% 89.1%
3730720 72.1.1.0 ↗ beta sandwiches › gamma-Crystallin-like › gamma-Crystallin-like › gamma-Crystallin-like 0.56 33.0 4.10e-01 82.7% 100.0%
None — 0.56 52.0 5.02e-01 98.7% 88.0%
1947 4242.1.1.1 ↗ beta sandwiches › WSSV envelope protein-like › WSSV envelope protein-like › WSSV envelope protein-like › WSS_VP 0.56 40.0 3.96e-01 73.7% 89.4%
5038901 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 39.0 4.33e-01 94.2% 90.8%
None — 0.56 51.0 4.91e-01 98.1% 86.9%
4984664 70.2.1.5 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like › DCD 0.56 52.0 4.91e-01 98.7% 85.6%
4947773 70.2.1.5 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like › DCD 0.55 51.0 5.04e-01 98.7% 95.2%
1948 4242.1.1.1 ↗ beta sandwiches › WSSV envelope protein-like › WSSV envelope protein-like › WSSV envelope protein-like › WSS_VP 0.55 42.0 4.22e-01 80.1% 95.7%
4941750 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.55 38.0 4.12e-01 92.9% 84.6%
3393074 11.1.1.495 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › MYCBPAP 0.55 40.0 4.33e-01 94.2% 91.5%
4962578 10.1.2.198 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) › DUF7383 0.54 38.0 4.05e-01 92.3% 84.6%
3897615 11.1.1.360 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › HYDIN_VesB_CFA65-like_Ig 0.54 37.0 4.15e-01 94.2% 92.2%
4381083 70.2.1.5 ↗ beta barrels › beta-clip › dUTPase-like › dUTPase-like › DCD 0.54 50.0 4.98e-01 98.7% 95.6%
3615451 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.54 38.0 4.23e-01 94.9% 91.2%
5033393 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.54 44.0 4.56e-01 93.6% 92.0%
356877 10.32.1.12 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › CBM_6 0.53 40.0 4.28e-01 92.3% 90.4%
3259122 10.4.1.0 ↗ beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain 0.53 35.0 3.93e-01 91.7% 88.7%
5062603 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 37.0 4.13e-01 94.2% 93.3%
3713401 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 39.0 4.24e-01 94.9% 93.1%
3897616 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 45.0 4.44e-01 94.9% 90.6%
3391036 11.1.1.495 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › MYCBPAP 0.52 38.0 4.03e-01 92.9% 86.7%
3923237 10.4.1.1 ↗ beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain › CUB 0.52 34.0 3.75e-01 92.3% 83.2%
4949004 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.51 40.0 3.99e-01 94.9% 80.5%
3714049 11.1.1.569 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Cep192_D7 0.51 36.0 3.95e-01 94.9% 89.6%
3996318 10.32.1.172 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › DDR1-2_DS-like 0.51 39.0 4.21e-01 92.9% 94.1%
3478144 10.32.1.2 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › F5_F8_type_C 0.50 40.0 3.62e-01 84.0% 73.3%
140303 10.32.1.2 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › F5_F8_type_C 0.50 40.0 4.12e-01 92.3% 88.8%
D2 high residues 148-272
PDB
Domain cluster: rep: GP72__YP_007417837__Caviid_betaherpesvirus_2__33706__D239-337
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00692.25 best dUTPase 82.1 4.30e-23 84.0% 75.2%