←Back to structures
dihydrofolate_reductase_motif-containing_protein
Euk-VirPandoravirus_inopinatum
dihydrofolate_reductase_motif-containing_protein__YP_009119045__Pandoravirus_inopinatum__1605721
Identity
- Accession:
- YP_009119045 ↗
- Protein ID:
- dihydrofolate_reductase_motif-containing_protein
- Kingdom:
- euk
Quality
62.2
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-131
Domain cluster:
representative
CATH (21)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4flbA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.70 | 44.0 | 4.40e-01 | 100.0% | 61.8% |
| 2fupA00 | 1.20.58.300 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like | 0.70 | 51.0 | 5.25e-01 | 75.6% | 100.0% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.66 | 48.0 | 5.06e-01 | 82.4% | 85.3% |
| 3ro3A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.65 | 41.0 | 3.87e-01 | 100.0% | 52.2% |
| 4i1eA03 | 1.25.10.30 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain | 0.64 | 54.0 | 5.35e-01 | 90.8% | 93.5% |
| 4ga0A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.63 | 35.0 | 3.43e-01 | 97.7% | 48.3% |
| 6u3wB00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.63 | 39.0 | 3.04e-01 | 100.0% | 27.5% |
| 3lmfA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.62 | 37.0 | 4.06e-01 | 84.0% | 71.6% |
| 3on4D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.60 | 53.0 | 4.69e-01 | 96.2% | 94.1% |
| 2q7fA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 34.0 | 2.99e-01 | 100.0% | 36.6% |
| 3eupB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 49.0 | 4.33e-01 | 94.7% | 88.0% |
| 2o7tA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 49.0 | 4.44e-01 | 95.4% | 91.9% |
| 1zu2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 40.0 | 3.81e-01 | 74.8% | 84.8% |
| 3vuqB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 47.0 | 4.25e-01 | 91.6% | 88.6% |
| 4mo7A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 43.0 | 4.26e-01 | 83.2% | 96.5% |
| 2vq2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 33.0 | 2.79e-01 | 100.0% | 34.1% |
| 5k7fA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 43.0 | 4.24e-01 | 83.2% | 97.1% |
| 8cdaB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 45.0 | 4.21e-01 | 87.8% | 100.0% |
| 4nn1A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 46.0 | 3.98e-01 | 96.9% | 85.9% |
| 3mkqA03 | 1.25.40.470 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 33.0 | 2.76e-01 | 98.5% | 39.6% |
| 2fx0A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 40.0 | 4.06e-01 | 84.7% | 97.0% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3223123 | 109.4.1.70 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID | 0.72 | 45.0 | 4.53e-01 | 100.0% | 61.5% |
| 3595433 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 42.0 | 3.71e-01 | 71.0% | 44.2% |
| 3167155 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 40.0 | 3.34e-01 | 100.0% | 35.1% |
| 3188308 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.64 | 57.0 | 4.49e-01 | 97.7% | 82.9% |
| 3288806 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 42.0 | 4.00e-01 | 100.0% | 56.2% |
| 3515022 | 109.4.1.192 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 | 0.62 | 46.0 | 4.08e-01 | 100.0% | 55.0% |
| 3213583 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 46.0 | 4.10e-01 | 100.0% | 55.1% |
| 3265567 | 5000.6.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Tethering factor for nuclear proteasome cut8 › Tethering factor for nuclear proteasome cut8 › Cut8 | 0.60 | 53.0 | 4.44e-01 | 100.0% | 56.4% |
| 3979534 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 43.0 | 3.37e-01 | 100.0% | 36.1% |
| 3870335 | 109.4.1.198 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 | 0.58 | 43.0 | 3.49e-01 | 78.6% | 44.3% |
| 4947493 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.55 | 43.0 | 4.25e-01 | 81.7% | 85.9% |
| 3984565 | 109.4.1.202 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_16 | 0.55 | 33.0 | 3.14e-01 | 100.0% | 47.5% |
| 4497855 | 5069.1.3.2 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Fumarate_red_C | 0.54 | 33.0 | 3.41e-01 | 99.2% | 65.0% |
| 3268533 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 42.0 | 3.42e-01 | 89.3% | 68.4% |
| 4092993 | 149.1.1.1 ↗ | alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 | 0.50 | 40.0 | 2.71e-01 | 83.2% | 73.0% |
| 3999694 | 109.26.1.12 ↗ | alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › TPR_Nup160_C, TPR_NUP160_120_M | 0.50 | 45.0 | 3.42e-01 | 100.0% | 43.5% |
D2
medium
residues 132-187
Domain cluster:
representative
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8bykA01 | 1.50.10.20 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.66 | 58.0 | 3.43e-01 | 98.2% | 34.2% |
| 7yb9A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.65 | 59.0 | 3.90e-01 | 100.0% | 28.4% |
| 3k7xA00 | 1.50.10.20 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.64 | 58.0 | 3.48e-01 | 98.2% | 30.0% |
| 7fhyB01 | 1.50.10.100 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase | 0.63 | 55.0 | 3.51e-01 | 100.0% | 40.5% |
| 2uy1A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.61 | 44.0 | 2.62e-01 | 78.6% | 11.0% |
| 4pxoA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.55 | 46.0 | 3.59e-01 | 98.2% | 72.5% |
| 2bs2A02 | 3.90.700.10 | Alpha Beta › Alpha-Beta Complex › Flavocytochrome C3; Chain A, domain 1 › Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0.54 | 40.0 | 3.36e-01 | 96.4% | 43.9% |
| 3pt9A02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.54 | 39.0 | 2.44e-01 | 76.8% | 20.7% |
| 1qlbA03 | 1.20.58.100 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain | 0.54 | 45.0 | 3.67e-01 | 100.0% | 52.5% |
| 4ewfA00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.51 | 42.0 | 2.80e-01 | 98.2% | 65.3% |
| 1rfmA01 | 1.10.1530.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel | 0.51 | 41.0 | 3.26e-01 | 94.6% | 93.9% |
| 2pjpA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.50 | 41.0 | 4.06e-01 | 100.0% | 83.6% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3838463 | 604.17.1.0 ↗ | alpha bundles › Spectrin repeat-like › MTH_863 C-terminal domain-like › MTH_863 C-terminal domain-like | 0.75 | 59.0 | 6.27e-01 | 100.0% | 94.0% |
| 3703129 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 58.0 | 3.89e-01 | 100.0% | 42.5% |
| 4013843 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 53.0 | 3.02e-01 | 98.2% | 13.0% |
| 164839 | 109.4.1.83 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Suf | 0.61 | 44.0 | 2.62e-01 | 78.6% | 11.0% |
| 3683429 | 109.4.1.22 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N | 0.61 | 53.0 | 3.19e-01 | 98.2% | 21.3% |
| 4068922 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.60 | 43.0 | 3.67e-01 | 82.1% | 63.8% |
| 5032961 | 101.1.2.894 ↗ | alpha arrays › HTH › HTH › winged helix domain › DUF2240 | 0.60 | 39.0 | 3.95e-01 | 94.6% | 67.3% |
| 3348879 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.56 | 40.0 | 4.20e-01 | 96.4% | 82.0% |
| 3603420 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 43.0 | 3.27e-01 | 92.9% | 63.1% |
| 3887896 | 109.3.1.96 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank+Ank_2+Ank_4 | 0.50 | 43.0 | 3.07e-01 | 100.0% | 39.5% |
D3
medium
residues 188-201_220-330_406-416
D4
medium
residues 417-553