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dihydrofolate_reductase_motif-containing_protein

Euk-Vir

Pandoravirus_inopinatum

dihydrofolate_reductase_motif-containing_protein__YP_009119784__Pandoravirus_inopinatum__1605721

Identity

Accession:
YP_009119784 ↗
Protein ID:
dihydrofolate_reductase_motif-containing_protein
Kingdom:
euk

Quality

52.6 mean pLDDT

Taxonomy

Pandoravirus› Pandoravirus_inopinatum

TaxID: 1605721

Cluster

View cluster (4 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 12-201
PDB
Domain cluster: rep: dihydrofolate_reductase__YP_009119754__Pandoravirus_inopinatum__1605721__D21-210
CATH (80)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2w9hA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.87 70.0 7.74e-01 90.5% 100.0%
5eccA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.87 70.0 7.65e-01 90.5% 99.4%
1ao8A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.87 72.0 7.80e-01 90.5% 100.0%
1dhiA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.86 70.0 7.68e-01 90.5% 100.0%
1vdrA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.85 68.0 7.52e-01 90.5% 100.0%
3ix9A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.85 71.0 7.61e-01 91.1% 98.8%
1bozA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.82 72.0 7.35e-01 91.6% 98.9%
1juvA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.81 70.0 6.98e-01 89.5% 100.0%
3k2hA01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.80 71.0 7.17e-01 91.6% 96.3%
4eckA01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.80 70.0 7.22e-01 90.5% 99.4%
6pf8A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.80 70.0 7.27e-01 90.5% 98.9%
1cz3B00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.80 67.0 7.14e-01 91.6% 98.2%
1aoeA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.78 68.0 6.85e-01 90.5% 97.9%
2xw7A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.78 68.0 7.10e-01 91.1% 97.7%
2b3zA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.78 68.0 6.39e-01 90.5% 94.7%
3vcoA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.78 68.0 6.94e-01 90.5% 98.4%
2p4gA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.78 68.0 6.18e-01 91.6% 92.3%
2aznA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.78 68.0 6.46e-01 91.1% 98.2%
3zpgA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.77 68.0 6.45e-01 90.5% 94.4%
2hxvA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.77 67.0 6.63e-01 90.5% 99.5%
3kgyA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.76 66.0 6.28e-01 90.5% 96.3%
2g6vA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.75 65.0 6.16e-01 90.5% 94.6%
2h2qB01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.75 65.0 6.29e-01 91.1% 89.6%
3jtwA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.73 63.0 6.60e-01 90.5% 98.9%
4xt6A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.73 62.0 5.75e-01 90.0% 89.5%
2gd9A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.66 55.0 5.84e-01 88.9% 99.4%
3axsA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.63 49.0 4.09e-01 81.1% 92.2%
5dlyA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 49.0 4.44e-01 83.2% 88.3%
1ri5A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 47.0 4.34e-01 80.5% 99.2%
3dlcA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.60 47.0 4.55e-01 82.6% 89.0%
1i4wA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 47.0 4.29e-01 82.1% 93.5%
2ip2A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 47.0 4.30e-01 82.6% 82.5%
3dh0B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 46.0 4.66e-01 81.6% 94.7%
6gnaA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.58 31.0 4.05e-01 72.6% 90.7%
1jsxA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 46.0 4.60e-01 82.6% 82.4%
3jwhA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 44.0 4.47e-01 80.0% 98.4%
4rv9A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 45.0 4.47e-01 82.1% 96.0%
1inlD01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 44.0 4.25e-01 79.5% 92.7%
4lg1B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 46.0 4.46e-01 84.2% 88.3%
1uirA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 46.0 4.22e-01 85.3% 94.1%
1pjqA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 34.0 4.29e-01 83.2% 99.1%
6qmmA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 43.0 4.19e-01 79.5% 93.6%
3m33A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 45.0 4.34e-01 82.1% 93.8%
3htxD03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 48.0 4.58e-01 90.5% 96.8%
3ccfA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 43.0 4.05e-01 79.5% 100.0%
2r3sA03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 45.0 4.34e-01 82.1% 94.3%
5gzjB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 45.0 4.52e-01 82.6% 95.2%
3e05B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 44.0 4.47e-01 81.6% 91.1%
5iceA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 44.0 4.09e-01 82.6% 94.4%
4pneA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 46.0 4.13e-01 85.8% 99.3%
1im8B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 44.0 4.21e-01 82.1% 96.0%
1jqbA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 40.0 4.53e-01 78.9% 98.6%
1ve3A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 45.0 4.36e-01 84.2% 100.0%
3fzgA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 44.0 4.45e-01 83.2% 87.2%
2o07A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 43.0 4.15e-01 80.0% 94.4%
3dliA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 44.0 4.23e-01 83.2% 99.5%
1af7A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 44.0 4.38e-01 81.6% 98.5%
3ihtA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 44.0 4.67e-01 82.6% 96.3%
3ed4C01 3.40.720.10 Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A 0.55 46.0 3.70e-01 89.5% 94.8%
2qm3A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 43.0 4.12e-01 82.1% 89.4%
6c49A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 39.0 4.33e-01 75.3% 90.8%
4xcxA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 46.0 4.45e-01 89.5% 94.9%
2i62A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 43.0 3.97e-01 83.2% 94.6%
4mtlA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 43.0 4.21e-01 83.2% 83.2%
2cf5A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 40.0 4.30e-01 75.3% 90.4%
2b3tA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 43.0 4.30e-01 82.1% 97.9%
2qyoA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 42.0 3.92e-01 82.1% 94.4%
2qy6A01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 43.0 4.01e-01 83.2% 95.3%
3dtnA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 42.0 4.30e-01 82.1% 89.8%
2b25A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 42.0 4.32e-01 81.6% 93.4%
6yu8A01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 44.0 3.99e-01 86.8% 89.6%
3bxoA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 42.0 4.33e-01 82.1% 94.4%
3f8dA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.53 32.0 3.91e-01 72.6% 91.9%
1nkvB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 42.0 3.93e-01 82.6% 96.5%
3gnlA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 41.0 4.39e-01 82.1% 95.8%
5tx7A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 39.0 3.99e-01 80.5% 97.9%
1r6aA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 40.0 3.65e-01 82.6% 74.8%
1qzzA03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 40.0 4.26e-01 83.2% 98.8%
5k8bA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.51 40.0 3.62e-01 81.6% 78.3%
6ewjB01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.50 39.0 3.53e-01 81.1% 80.3%
ECOD (92)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3963884 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.88 71.0 7.75e-01 89.5% 98.8%
2831687 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.88 71.0 7.51e-01 90.5% 91.9%
169540 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.88 72.0 7.74e-01 91.1% 97.0%
4624802 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.87 73.0 7.86e-01 91.1% 100.0%
4279950 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.86 73.0 7.81e-01 91.6% 100.0%
4563316 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.86 73.0 7.82e-01 93.7% 100.0%
4965070 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.85 71.0 7.44e-01 90.5% 93.1%
4652224 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.85 71.0 7.65e-01 91.1% 99.4%
4295510 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.85 70.0 7.61e-01 91.6% 100.0%
137968 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.85 71.0 7.61e-01 91.1% 98.8%
2847460 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.85 66.0 7.28e-01 91.1% 97.4%
4392683 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.83 69.0 7.43e-01 90.5% 98.8%
3900511 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.82 73.0 7.44e-01 91.6% 99.5%
3913441 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.82 73.0 7.32e-01 91.6% 98.4%
3263045 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.82 72.0 7.12e-01 91.6% 96.0%
4315799 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.82 71.0 7.46e-01 90.5% 99.4%
10266 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.81 70.0 6.98e-01 89.5% 100.0%
136031 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.81 70.0 6.73e-01 90.5% 99.1%
4183099 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.81 71.0 7.34e-01 92.1% 96.1%
4123104 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.80 67.0 7.18e-01 90.5% 98.8%
2503171 7501.1.1.1 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.80 70.0 7.23e-01 91.1% 97.8%
4577003 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.79 70.0 6.67e-01 91.6% 98.6%
3432837 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.79 69.0 6.42e-01 91.1% 91.7%
4946280 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.79 69.0 6.49e-01 90.5% 98.6%
4663296 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.79 70.0 6.59e-01 92.1% 99.1%
4238819 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.79 69.0 6.55e-01 91.6% 98.2%
4959428 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.79 69.0 6.48e-01 91.6% 96.4%
5057520 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.78 68.0 6.43e-01 90.0% 92.7%
4033392 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.78 68.0 6.58e-01 90.5% 98.1%
3385448 7501.1.1.0 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases 0.78 62.0 6.79e-01 89.5% 97.5%
4992215 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.78 68.0 6.52e-01 91.1% 98.6%
4262258 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.78 68.0 6.38e-01 91.1% 95.1%
235716 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.78 68.0 6.58e-01 91.1% 99.5%
4968801 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.77 67.0 6.27e-01 90.5% 90.4%
3953555 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.77 67.0 6.79e-01 90.5% 97.9%
5058063 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.77 67.0 7.01e-01 91.1% 98.9%
3590464 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.77 67.0 6.99e-01 90.5% 98.8%
5029141 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.77 66.0 6.88e-01 91.1% 96.6%
5001085 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.76 68.0 6.26e-01 92.6% 93.2%
3839944 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.76 64.0 6.66e-01 90.5% 93.9%
3284365 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.75 65.0 6.54e-01 91.1% 99.0%
3278543 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.75 65.0 6.52e-01 90.5% 98.9%
4949256 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.74 65.0 6.12e-01 90.5% 98.6%
5082494 7501.1.1.2 ↗ a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.72 63.0 5.99e-01 91.6% 98.6%
3207850 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.64 51.0 4.37e-01 83.2% 93.7%
5041637 2003.1.5.19 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › TRM 0.64 49.0 4.28e-01 78.9% 88.9%
3951045 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.62 49.0 4.41e-01 82.6% 95.8%
5039593 2003.1.5.26 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_28 0.61 49.0 3.94e-01 84.2% 80.3%
3629519 2003.1.5.73 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_16 0.60 48.0 4.22e-01 83.7% 75.4%
3376947 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.60 47.0 4.01e-01 82.1% 89.2%
5073415 2003.1.5.82 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.59 48.0 4.60e-01 84.2% 94.0%
None — 0.59 47.0 4.28e-01 84.2% 78.3%
4998240 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.59 46.0 4.69e-01 81.1% 94.0%
None — 0.59 46.0 4.49e-01 82.6% 90.0%
3663236 2003.1.5.67 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12 0.58 50.0 4.66e-01 92.1% 97.9%
5055722 2003.1.5.79 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.58 45.0 4.31e-01 81.6% 97.3%
5025354 2003.1.5.8 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Ubie_methyltran 0.58 46.0 4.52e-01 83.2% 100.0%
4657002 2003.1.5.152 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CMAS, Methyltransf_25 0.58 46.0 3.98e-01 83.7% 95.0%
3290078 321.4.1.0 ↗ a+b two layers › Glutamine synthetase-like › Methyltransferase type 12 N-terminal domain › Methyltransferase type 12 N-terminal domain 0.58 45.0 3.41e-01 81.6% 43.6%
3887399 2003.1.5.73 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_16 0.58 45.0 3.84e-01 81.6% 59.7%
4960172 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.58 45.0 4.44e-01 83.2% 83.3%
3262393 2003.1.5.73 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_16 0.58 46.0 4.16e-01 83.7% 84.7%
5012847 2003.1.5.79 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.57 45.0 4.26e-01 82.6% 84.7%
5042678 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.57 44.0 4.41e-01 81.1% 97.0%
None — 0.57 46.0 3.71e-01 85.3% 94.9%
3279159 2003.1.5.152 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CMAS, Methyltransf_25 0.57 44.0 3.95e-01 82.1% 97.1%
3346541 2003.1.5.13 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Spermine_synth 0.57 45.0 4.17e-01 83.7% 97.6%
4679950 2003.1.5.8 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Ubie_methyltran 0.57 45.0 4.17e-01 83.2% 89.4%
3967803 2003.1.5.27 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › NAS 0.57 46.0 4.24e-01 86.3% 86.0%
3307502 2003.1.5.6 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltr_RsmB-F 0.57 44.0 3.96e-01 81.6% 75.1%
3878855 2003.1.5.46 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS 0.56 44.0 4.19e-01 82.1% 88.9%
3253912 2003.1.5.73 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_16 0.56 43.0 4.40e-01 81.6% 93.7%
3287417 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.56 44.0 3.81e-01 81.6% 83.3%
2389473 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.56 45.0 4.26e-01 85.3% 98.2%
3279773 2003.1.5.152 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CMAS, Methyltransf_25 0.56 44.0 3.90e-01 82.6% 93.2%
3386491 2003.1.5.67 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12 0.56 43.0 3.75e-01 80.5% 67.9%
4474145 2003.1.5.25 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GidB 0.55 45.0 4.26e-01 84.7% 76.3%
4645737 2003.1.5.46 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS 0.55 43.0 4.21e-01 81.6% 93.8%
3449915 2003.1.5.46 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS 0.55 44.0 3.70e-01 82.6% 68.9%
3395187 2003.1.5.58 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Bin3 0.55 44.0 4.18e-01 84.2% 97.4%
3519315 2003.1.5.58 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Bin3 0.55 44.0 3.83e-01 84.7% 87.6%
5039054 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.55 43.0 4.36e-01 82.1% 89.2%
4085907 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.55 42.0 3.52e-01 81.1% 68.7%
4378921 2003.1.5.25 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GidB 0.55 43.0 4.20e-01 82.6% 79.3%
3472358 2003.1.5.117 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › DREV 0.54 44.0 3.77e-01 84.7% 89.7%
4382894 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.54 42.0 3.90e-01 82.1% 90.2%
5001349 2003.1.5.82 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.54 42.0 4.38e-01 81.1% 99.4%
5013470 2003.1.5.82 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.54 41.0 4.10e-01 80.5% 87.5%
4381350 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.53 42.0 3.90e-01 82.6% 96.3%
3626497 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.53 42.0 3.80e-01 84.7% 87.4%
5072560 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.52 41.0 3.95e-01 82.6% 79.1%
5071911 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.50 40.0 3.86e-01 84.7% 99.6%
D2 medium residues 404-454
PDB
D3 medium residues 471-671
PDB
D4 medium residues 672-686_702-763_804-829
PDB