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dihydrofolate_reductase_motif-containing_protein
Euk-VirPandoravirus_inopinatum
dihydrofolate_reductase_motif-containing_protein__YP_009119785__Pandoravirus_inopinatum__1605721
Identity
- Accession:
- YP_009119785 ↗
- Protein ID:
- dihydrofolate_reductase_motif-containing_protein
- Kingdom:
- euk
Quality
59.5
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 43-157_171-182
Domain cluster:
rep: dihydrofolate_reductase_motif-containing_protein__YP_009119044__Pandoravirus_inopinatum__1605721__D42-164
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3zpjA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.67 | 47.0 | 3.39e-01 | 100.0% | 25.8% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.62 | 36.0 | 4.24e-01 | 81.9% | 83.5% |
| 1oxjA02 | 1.25.40.170 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Smaug, PHAT domain | 0.60 | 46.0 | 4.90e-01 | 100.0% | 94.5% |
| 3q5dA02 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.60 | 35.0 | 3.91e-01 | 80.3% | 74.2% |
| 1x5bA01 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.59 | 43.0 | 4.26e-01 | 100.0% | 71.1% |
| 6wb9201 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.58 | 40.0 | 3.12e-01 | 100.0% | 31.1% |
| 4jhrB00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 39.0 | 3.03e-01 | 100.0% | 31.5% |
| 3i9yA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 35.0 | 2.88e-01 | 77.2% | 34.9% |
| 6ziwI02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.56 | 45.0 | 4.04e-01 | 87.4% | 91.2% |
| 2cz2A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.55 | 39.0 | 3.97e-01 | 90.6% | 73.8% |
| 2kmgA00 | 3.30.70.3580 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Antirestriction protein | 0.54 | 43.0 | 4.18e-01 | 93.7% | 76.1% |
| 3r2cA00 | 1.10.940.10 | Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like | 0.54 | 44.0 | 4.33e-01 | 89.0% | 95.7% |
| 2pfdA03 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.54 | 47.0 | 4.04e-01 | 95.3% | 80.8% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.54 | 36.0 | 3.84e-01 | 84.3% | 78.9% |
| 3i4gA00 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 42.0 | 2.84e-01 | 100.0% | 21.2% |
| 2rkkA01 | 1.25.40.270 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 | 0.53 | 43.0 | 4.05e-01 | 89.0% | 84.6% |
| 2ktyA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.52 | 43.0 | 3.59e-01 | 89.0% | 75.7% |
| 3tt9A00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.52 | 38.0 | 3.13e-01 | 100.0% | 40.8% |
| 2jiiA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.52 | 42.0 | 3.64e-01 | 87.4% | 88.5% |
| 7ml0M01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.52 | 32.0 | 3.79e-01 | 96.1% | 95.1% |
| 4iv6B01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.51 | 35.0 | 3.63e-01 | 91.3% | 75.9% |
| 2wwxB00 | 1.20.1260.70 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.51 | 41.0 | 3.55e-01 | 100.0% | 55.0% |
| 3snxA00 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 43.0 | 2.98e-01 | 92.9% | 27.7% |
| 6z0fA02 | 1.25.40.680 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type VII secretion system EssB, C-terminal-like domain | 0.51 | 39.0 | 3.59e-01 | 100.0% | 62.7% |
| 4nfnA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.50 | 41.0 | 3.56e-01 | 89.8% | 80.9% |
| 3tdvA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.50 | 38.0 | 3.27e-01 | 80.3% | 98.5% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3795211 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 51.0 | 4.38e-01 | 100.0% | 55.9% |
| 3442109 | 109.4.1.18 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPTA | 0.60 | 41.0 | 3.03e-01 | 100.0% | 26.7% |
| 4629051 | 109.4.1.317 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Med5 | 0.58 | 44.0 | 3.69e-01 | 100.0% | 47.0% |
| 3403421 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 50.0 | 4.73e-01 | 100.0% | 80.4% |
| 4484086 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 47.0 | 3.73e-01 | 100.0% | 43.0% |
| 4992256 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.57 | 38.0 | 4.18e-01 | 83.5% | 86.9% |
| 4182059 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.56 | 36.0 | 3.83e-01 | 81.1% | 74.5% |
| 3661495 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 49.0 | 4.20e-01 | 100.0% | 70.0% |
| 3645720 | 109.4.1.18 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPTA | 0.54 | 38.0 | 3.67e-01 | 100.0% | 62.7% |
| 3560386 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 43.0 | 3.70e-01 | 100.0% | 54.3% |
| 3902495 | 603.1.1.23 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Sec20 | 0.52 | 43.0 | 3.62e-01 | 91.3% | 67.7% |
| 3636792 | 109.4.1.1935 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF2428, TPR_Trm732, PF26523 | 0.50 | 45.0 | 2.76e-01 | 100.0% | 15.7% |
| 3207708 | 109.4.1.1982 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26523 | 0.50 | 45.0 | 3.95e-01 | 99.2% | 89.9% |