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disulfide_oxidoreductase
Euk-VirPithovirus_sibericum
disulfide_oxidoreductase__YP_009001368__Pithovirus_sibericum__1450746
Identity
- Accession:
- YP_009001368 ↗
- Protein ID:
- disulfide_oxidoreductase
- Kingdom:
- euk
Quality
69.5
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Pithoviridae›
Alphapithovirus›
Pithovirus_sibericum
TaxID: 1450746
Cluster
View cluster (24 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 53-155
Domain cluster:
rep: Ervl-Alr_family_protein__YP_009342175__Lymphocystis_disease_virus_Sa__1898060__D32-125
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04777.19 best | Evr1_Alr | 52.2 | 9.10e-14 | 96.1% | 93.5% |
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3gwlA00 | 1.20.120.310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain | 0.85 | 79.0 | 7.84e-01 | 100.0% | 94.3% |
| 1oqcA00 | 1.20.120.310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain | 0.85 | 76.0 | 7.38e-01 | 100.0% | 86.6% |
| 1jr8A00 | 1.20.120.310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain | 0.85 | 75.0 | 7.54e-01 | 100.0% | 92.4% |
| 3llkA01 | 1.20.120.1960 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › QSOX sulfhydryl oxidase domain | 0.67 | 53.0 | 5.40e-01 | 90.3% | 87.8% |
| 1j8yF01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.67 | 52.0 | 5.58e-01 | 87.4% | 100.0% |
| 2qupA00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.66 | 53.0 | 5.08e-01 | 86.4% | 86.6% |
| 2qkwB02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.66 | 50.0 | 4.01e-01 | 80.6% | 92.0% |
| 1yjgA00 | 1.20.120.240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 | 0.63 | 51.0 | 4.45e-01 | 88.3% | 94.9% |
| 1cpqA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.61 | 49.0 | 4.62e-01 | 88.3% | 94.6% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.60 | 49.0 | 3.93e-01 | 87.4% | 91.0% |
| 2hytA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 47.0 | 3.91e-01 | 88.3% | 59.6% |
| 5tkyA05 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.57 | 36.0 | 3.90e-01 | 70.9% | 74.7% |
| 2e9fB01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.57 | 41.0 | 4.23e-01 | 73.8% | 82.3% |
| 2pywA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.57 | 42.0 | 3.08e-01 | 77.7% | 98.3% |
| 2c0kB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.57 | 36.0 | 3.24e-01 | 96.1% | 44.3% |
| 1or7B01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.56 | 40.0 | 4.20e-01 | 73.8% | 94.7% |
| 1yowA00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.55 | 46.0 | 3.62e-01 | 93.2% | 76.5% |
| 3rk6A00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.54 | 39.0 | 3.07e-01 | 74.8% | 37.8% |
| 3w6bB00 | 1.10.530.10 | Mainly Alpha › Orthogonal Bundle › Lysozyme › | 0.54 | 41.0 | 3.62e-01 | 81.6% | 74.5% |
| 2lseA00 | 1.20.120.1360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.54 | 42.0 | 4.27e-01 | 82.5% | 88.1% |
| 2hfiA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.53 | 42.0 | 4.00e-01 | 86.4% | 95.1% |
| 4p9fA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.52 | 42.0 | 3.79e-01 | 87.4% | 66.7% |
| 1x42A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.52 | 36.0 | 3.99e-01 | 71.8% | 89.2% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.51 | 30.0 | 3.12e-01 | 88.3% | 61.0% |
| 3a98A02 | 1.20.1270.350 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain | 0.51 | 38.0 | 4.06e-01 | 83.5% | 94.3% |
| 3if8B02 | 1.20.58.730 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 37.0 | 3.79e-01 | 77.7% | 90.0% |
| 6gwuD00 | 3.40.1050.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase | 0.51 | 45.0 | 3.63e-01 | 100.0% | 72.3% |
| 2c61A00 | 3.40.50.12240 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.50 | 43.0 | 2.96e-01 | 100.0% | 45.9% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3211559 | 601.21.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › FAD-dependent thiol oxidase › FAD-dependent thiol oxidase › Evr1_Alr | 0.88 | 79.0 | 7.07e-01 | 100.0% | 70.3% |
| 3345939 | 601.21.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › FAD-dependent thiol oxidase › FAD-dependent thiol oxidase › Evr1_Alr | 0.86 | 77.0 | 7.28e-01 | 100.0% | 80.8% |
| 3172977 | 601.21.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › FAD-dependent thiol oxidase › FAD-dependent thiol oxidase › Evr1_Alr | 0.85 | 76.0 | 6.96e-01 | 100.0% | 74.6% |
| 135564 | 601.21.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › FAD-dependent thiol oxidase › FAD-dependent thiol oxidase › Evr1_Alr | 0.85 | 79.0 | 7.84e-01 | 100.0% | 94.3% |
| 54687 | 601.21.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › FAD-dependent thiol oxidase › FAD-dependent thiol oxidase | 0.85 | 76.0 | 7.35e-01 | 100.0% | 86.6% |
| 54681 | 601.21.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › FAD-dependent thiol oxidase › FAD-dependent thiol oxidase | 0.85 | 75.0 | 7.52e-01 | 100.0% | 92.4% |
| 3596726 | 601.21.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › FAD-dependent thiol oxidase › FAD-dependent thiol oxidase | 0.85 | 77.0 | 7.39e-01 | 100.0% | 86.1% |
| 3697926 | 601.21.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › FAD-dependent thiol oxidase › FAD-dependent thiol oxidase › Evr1_Alr | 0.84 | 76.0 | 6.46e-01 | 100.0% | 62.7% |
| 3740234 | 109.46.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) › CTLH | 0.61 | 49.0 | 4.57e-01 | 87.4% | 99.2% |
| 3179721 | 109.46.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) › CTLH | 0.59 | 50.0 | 3.95e-01 | 91.3% | 63.3% |
| 4420204 | 1037.1.1.1 ↗ | alpha bundles › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › LGT | 0.59 | 52.0 | 3.93e-01 | 99.0% | 68.7% |
| 3562699 | 3736.1.1.0 ↗ | alpha superhelices › NLRC4 helical domain HD2 › NLRC4 helical domain HD2 › NLRC4 helical domain HD2 | 0.59 | 38.0 | 3.61e-01 | 100.0% | 54.2% |
| 4196844 | 109.46.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) › CTLH | 0.57 | 45.0 | 3.83e-01 | 85.4% | 70.3% |
| 4983734 | 3646.1.1.1 ↗ | alpha complex topology › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters › CbiQ | 0.57 | 46.0 | 3.52e-01 | 88.3% | 46.4% |
| 3874682 | 109.46.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) › CTLH | 0.56 | 47.0 | 4.30e-01 | 91.3% | 97.0% |
| 3272472 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 46.0 | 3.29e-01 | 95.1% | 40.0% |
| 4313333 | 109.46.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) › CTLH | 0.55 | 47.0 | 3.62e-01 | 94.2% | 58.3% |
| 3736716 | 109.4.1.441 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TFCD_C | 0.55 | 40.0 | 3.48e-01 | 100.0% | 47.1% |
| 3166681 | 101.1.10.22 ↗ | alpha arrays › HTH › HTH › Cyclin-like › ORC6 | 0.52 | 37.0 | 3.75e-01 | 76.7% | 81.9% |
| 3740824 | 101.1.10.22 ↗ | alpha arrays › HTH › HTH › Cyclin-like › ORC6 | 0.51 | 35.0 | 3.61e-01 | 94.2% | 74.7% |
| 3742230 | 109.4.1.167 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Rif1_N | 0.51 | 38.0 | 2.60e-01 | 81.6% | 37.5% |
| 3925720 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.51 | 44.0 | 3.35e-01 | 100.0% | 73.2% |
| 3689499 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 45.0 | 3.38e-01 | 100.0% | 86.5% |
| 4928682 | 5060.2.1.0 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain | 0.51 | 41.0 | 3.88e-01 | 89.3% | 85.6% |