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dna-pol

Euk-Vir

Oxyplax_ochracea_nucleopolyhedrovirus

dna-pol__YP_009666600__Oxyplax_ochracea_nucleopolyhedrovirus__2083176

Identity

Accession:
YP_009666600 ↗
Protein ID:
dna-pol
Kingdom:
euk

Quality

84.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-15_186-420
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF10108.16 best DNA_pol_B_exo2 34.2 3.00e-08 83.9% 72.6%
PF03104.26 DNA_pol_B_exo1 73.3 3.00e-20 72.3% 73.1%
D2 medium residues 500-542_612-729
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 59.9 3.00e-16 80.1% 25.4%
PF00136.27 DNA_pol_B 27.3 2.20e-06 27.3% 9.0%
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3qexA03 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.85 82.0 6.95e-01 100.0% 95.1%
2gv9B04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.84 78.0 7.18e-01 96.3% 96.4%
4fxdA05 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.83 55.0 6.42e-01 96.3% 91.5%
1q8iA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.82 75.0 6.69e-01 100.0% 72.2%
2nyiA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.75 38.0 5.37e-01 90.7% 98.8%
1s5jA03 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.74 66.0 6.75e-01 98.8% 94.9%
2f5gA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.72 44.0 4.91e-01 81.4% 76.2%
1xmbA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.71 43.0 5.37e-01 89.4% 96.0%
2mq8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.71 43.0 4.99e-01 88.2% 84.8%
3uebF00 3.30.300.100 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like 0.68 41.0 5.04e-01 73.9% 96.0%
5t0oA02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.67 41.0 4.94e-01 85.1% 94.2%
1f3vA00 3.30.70.680 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › TRADD, N-terminal domain 0.66 47.0 4.77e-01 91.3% 74.1%
2fyxA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.66 46.0 5.09e-01 87.6% 88.5%
4djbA00 3.30.70.2870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 0.65 44.0 5.03e-01 81.4% 93.2%
7rsfA01 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 46.0 5.25e-01 88.8% 99.2%
3pfoA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 48.0 5.36e-01 88.8% 99.2%
1jyoA00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.63 35.0 3.89e-01 76.4% 66.9%
1y0hB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 38.0 4.66e-01 81.4% 98.0%
4kw3A00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.61 50.0 4.23e-01 87.0% 86.8%
4mmoA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 47.0 4.68e-01 80.1% 97.6%
4cllA01 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.60 52.0 4.73e-01 92.5% 70.5%
3cxjA00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.60 38.0 3.99e-01 76.4% 70.1%
5k9fA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 37.0 4.54e-01 82.0% 99.0%
5ixuA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 37.0 4.46e-01 82.0% 99.0%
3ng0A02 3.30.590.10 Alpha Beta › 2-Layer Sandwich › Creatine Kinase; Chain A, domain 2 › Glutamine synthetase/guanido kinase, catalytic domain 0.58 49.0 3.82e-01 90.7% 81.9%
3b8pA00 3.30.1890.10 Alpha Beta › 2-Layer Sandwich › Bacterial polysaccharide co-polymerase-like › FepE-like 0.58 50.0 4.54e-01 90.1% 96.6%
2pmbA01 3.30.1850.10 Alpha Beta › 2-Layer Sandwich › MCP/YpsA-like › MoCo carrier protein-like 0.58 37.0 4.48e-01 73.3% 97.2%
2ns9A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.57 41.0 4.27e-01 73.9% 99.3%
4er8A00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.56 47.0 4.68e-01 88.8% 90.3%
4zxwB01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.54 39.0 3.87e-01 75.2% 79.7%
1fm4A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.53 39.0 3.94e-01 75.2% 94.3%
1q2lA04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.52 45.0 4.06e-01 94.4% 87.7%
2il5A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.52 38.0 3.82e-01 74.5% 95.1%
ECOD (81)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5005286 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.88 85.0 6.62e-01 100.0% 87.5%
5019480 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.88 84.0 5.27e-01 100.0% 35.7%
3628202 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.85 82.0 5.19e-01 100.0% 36.8%
3558196 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.83 80.0 6.41e-01 100.0% 85.6%
4997717 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.82 79.0 6.13e-01 100.0% 85.2%
4939489 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.82 80.0 7.35e-01 100.0% 91.8%
3684974 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.81 79.0 4.99e-01 100.0% 38.9%
3968795 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.81 78.0 6.37e-01 100.0% 86.3%
4891101 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.81 65.0 6.37e-01 83.2% 97.7%
4944522 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.80 77.0 6.53e-01 100.0% 96.3%
3801150 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.80 77.0 6.11e-01 100.0% 81.4%
5017083 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.80 77.0 6.27e-01 100.0% 85.2%
5025209 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.78 75.0 6.47e-01 100.0% 94.0%
4958554 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.78 75.0 6.43e-01 100.0% 95.3%
4981193 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.77 74.0 6.19e-01 100.0% 85.1%
4282509 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.77 73.0 4.85e-01 100.0% 31.0%
5073476 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.77 75.0 6.38e-01 100.0% 89.4%
4942685 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.77 74.0 5.03e-01 100.0% 44.9%
4944179 304.43.1.0 a+b two layers › Alpha-beta plaits › Hypothetical protein TT1725 › Hypothetical protein TT1725 0.76 46.0 5.66e-01 80.7% 95.0%
4932480 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.76 74.0 6.49e-01 100.0% 96.8%
4956224 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.76 74.0 6.33e-01 100.0% 90.6%
4959101 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.75 73.0 6.15e-01 100.0% 91.8%
5044377 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.75 72.0 6.10e-01 100.0% 92.7%
5041308 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.74 72.0 5.85e-01 100.0% 94.8%
4977369 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.74 72.0 6.00e-01 100.0% 86.4%
4977732 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.74 71.0 6.17e-01 100.0% 93.9%
3516510 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.74 53.0 6.06e-01 90.1% 98.3%
4978605 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.73 71.0 5.66e-01 100.0% 75.1%
4483977 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.73 44.0 5.47e-01 82.0% 96.0%
4982660 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.73 70.0 6.25e-01 100.0% 90.2%
5025843 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.73 70.0 6.30e-01 100.0% 90.5%
4461958 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.72 70.0 5.93e-01 100.0% 83.3%
4933206 304.39.1.0 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.71 37.0 4.91e-01 73.3% 95.3%
4100823 4970.1.1.1 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.70 67.0 5.65e-01 100.0% 82.8%
3578106 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.70 66.0 5.43e-01 100.0% 82.9%
5040510 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.70 67.0 5.68e-01 100.0% 92.7%
3474156 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.69 64.0 5.28e-01 100.0% 82.5%
5074889 878.1.1.1 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.68 41.0 5.12e-01 72.7% 100.0%
4975956 3501.1.1.0 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 0.68 35.0 4.60e-01 73.9% 91.8%
3381141 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.68 62.0 6.12e-01 96.9% 96.5%
5025783 304.162.1.0 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain 0.68 36.0 4.69e-01 77.0% 95.3%
3340180 304.39.1.0 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.68 40.0 4.89e-01 84.5% 93.0%
4934927 304.19.1.0 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain 0.66 35.0 4.61e-01 75.8% 95.3%
3882670 304.47.1.1 a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA 0.65 43.0 5.07e-01 88.8% 97.3%
3015534 304.48.1.12 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Mononeg_RNA_pol 0.64 54.0 4.00e-01 88.8% 77.0%
3290869 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.64 47.0 5.24e-01 80.1% 96.8%
4997627 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.64 48.0 5.34e-01 88.2% 97.7%
3485236 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.63 53.0 5.68e-01 91.9% 100.0%
5077735 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.63 48.0 5.37e-01 78.9% 100.0%
3545474 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.63 34.0 4.31e-01 73.3% 91.1%
984477 878.1.1.1 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.63 39.0 4.70e-01 73.9% 98.0%
4962702 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.62 47.0 5.21e-01 88.8% 100.0%
4976493 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.61 43.0 4.94e-01 83.2% 97.5%
4997823 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.61 47.0 5.13e-01 80.7% 98.5%
141279 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.60 46.0 5.04e-01 88.8% 96.9%
3966868 304.25.1.0 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain 0.60 44.0 4.92e-01 89.4% 96.8%
5009622 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.60 43.0 4.88e-01 88.8% 96.0%
3713509 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.60 55.0 4.89e-01 100.0% 92.2%
3699604 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.59 46.0 4.97e-01 80.7% 95.6%
149202 321.1.1.1 a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase › Gln-synt_C 0.59 50.0 3.78e-01 90.7% 76.1%
3959611 304.42.1.0 a+b two layers › Alpha-beta plaits › Molybdenum cofactor biosynthesis protein C, MoaC › Molybdenum cofactor biosynthesis protein C, MoaC 0.59 45.0 4.79e-01 88.8% 92.1%
4496753 241.1.1.8 a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › DUF2170 0.59 32.0 3.57e-01 73.9% 65.4%
4980045 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.58 46.0 4.95e-01 81.4% 98.5%
4945880 304.42.1.1 a+b two layers › Alpha-beta plaits › Molybdenum cofactor biosynthesis protein C, MoaC › Molybdenum cofactor biosynthesis protein C, MoaC › MoaC 0.58 44.0 4.67e-01 81.4% 88.3%
3484794 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.58 31.0 4.07e-01 80.7% 100.0%
3605864 304.19.1.0 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain 0.57 50.0 4.40e-01 92.5% 73.0%
3970706 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.56 42.0 4.58e-01 88.2% 96.2%
3278261 304.28.1.13 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › MMPL 0.55 47.0 4.94e-01 88.8% 98.6%
4999371 241.1.1.0 a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone 0.55 43.0 4.49e-01 87.0% 88.0%
3846107 309.1.1.11 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › PqqF-like_C_4 0.55 47.0 3.99e-01 91.9% 85.0%
3971531 304.25.1.0 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain 0.54 40.0 4.34e-01 80.7% 91.9%
3340749 309.1.1.11 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › PqqF-like_C_4 0.54 47.0 4.09e-01 91.9% 86.4%
3691833 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.54 38.0 3.54e-01 73.3% 74.6%
3227268 309.1.1.23 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C, Peptidase_M16_M, PqqF-like_C_4 0.53 42.0 3.13e-01 83.9% 64.9%
3164823 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.53 46.0 4.06e-01 91.9% 88.3%
4321285 323.1.1.5 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation 0.53 38.0 3.77e-01 73.3% 77.6%
3596254 304.25.1.0 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain 0.53 38.0 4.27e-01 80.1% 97.6%
3201303 323.1.1.5 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation 0.52 37.0 3.22e-01 73.9% 79.6%
4556741 309.1.1.11 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › PqqF-like_C_4 0.51 43.0 4.26e-01 90.1% 92.0%
3856140 331.2.1.0 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain 0.51 38.0 4.08e-01 78.3% 98.6%
4324362 323.1.1.5 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation 0.51 35.0 3.32e-01 71.4% 69.2%
D3 medium residues 730-794_872-935
PDB
Domain cluster: representative
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4fxdA06 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.75 56.0 5.16e-01 77.5% 100.0%
3iayA07 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.74 56.0 5.25e-01 78.3% 100.0%
5bqnA02 1.20.1120.10 Mainly Alpha › Up-down Bundle › "Clostridium botulinum neurotoxin B, ""coiled-coil"" domain" › "Clostridium botulinum neurotoxin b, ""coiled-coil"" domain" 0.71 56.0 4.03e-01 82.9% 60.1%
4qclA05 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.68 57.0 5.21e-01 89.1% 100.0%
2lsgA00 1.20.58.1280 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DNA repair protein Rev1, C-terminal domain 0.68 46.0 5.18e-01 83.7% 91.8%
3draA00 1.25.40.120 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Protein prenylyltransferase 0.64 43.0 3.27e-01 86.0% 28.8%
1tgoA05 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.64 54.0 4.95e-01 89.9% 96.4%
2jbwA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.56 39.0 4.25e-01 85.3% 90.3%
1tqgA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.56 32.0 3.52e-01 88.4% 68.6%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.55 36.0 3.67e-01 86.0% 65.4%
3rbtA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 37.0 3.89e-01 82.2% 77.8%
7dswA01 1.20.1530.20 Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › 0.52 41.0 2.91e-01 84.5% 84.0%
1xzpA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.51 36.0 3.34e-01 71.3% 65.7%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3480544 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.75 59.0 5.37e-01 81.4% 100.0%
4944523 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.74 54.0 5.10e-01 74.4% 100.0%
3167790 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.74 55.0 5.24e-01 77.5% 100.0%
3314223 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.73 57.0 5.25e-01 80.6% 100.0%
3705557 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.72 54.0 5.06e-01 78.3% 100.0%
3169738 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.72 57.0 5.25e-01 83.7% 100.0%
5031722 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.72 55.0 5.06e-01 79.1% 94.4%
4297578 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.71 53.0 4.97e-01 76.7% 95.5%
3404727 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.71 55.0 4.75e-01 80.6% 83.5%
3365808 109.4.1.1475 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF27629 0.71 58.0 4.13e-01 86.8% 36.7%
3597971 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.69 61.0 5.41e-01 95.3% 97.8%
4547010 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.68 60.0 5.34e-01 95.3% 97.2%
3520971 4969.1.1.2 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › POL2_thumb 0.66 59.0 4.81e-01 96.1% 88.7%
3940596 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 47.0 4.44e-01 85.3% 60.6%
4959102 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.63 53.0 4.90e-01 92.2% 100.0%
3724992 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.61 46.0 3.62e-01 79.1% 73.2%
3827754 109.4.1.888 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT_Syf1_CNRKL1_N 0.55 43.0 4.47e-01 93.8% 93.0%
3412611 189.1.1.0 alpha bundles › GTPase activation domain, GAP › GTPase activation domain, GAP › GTPase activation domain, GAP 0.55 43.0 3.35e-01 83.7% 50.5%
3914725 109.4.1.739 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FemAB 0.53 36.0 3.27e-01 80.6% 49.7%
3832977 109.4.1.1475 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF27629 0.52 45.0 3.73e-01 96.9% 79.6%
3980116 601.18.1.0 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.51 34.0 3.62e-01 83.7% 78.2%
4004414 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.51 34.0 3.60e-01 83.7% 78.2%
3945101 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.50 33.0 3.57e-01 85.3% 78.2%
3308733 5069.1.1.56 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PF27518 0.50 36.0 3.08e-01 76.0% 63.5%
D4 medium residues 819-871
PDB