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e41.1

Euk-Vir

Murid_betaherpesvirus_8

e41.1__YP_007016447__Murid_betaherpesvirus_8__1261657

Identity

Accession:
YP_007016447 ↗
Protein ID:
e41.1
Kingdom:
euk

Quality

70.6 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-54
PDB
Domain cluster: representative
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.83 76.0 6.62e-01 100.0% 74.4%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.83 66.0 5.61e-01 88.9% 54.0%
7s0rB01 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.79 59.0 5.26e-01 87.0% 56.6%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.78 70.0 4.50e-01 100.0% 24.0%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.77 67.0 4.93e-01 100.0% 39.5%
7wivA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.77 69.0 4.26e-01 100.0% 19.2%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 66.0 6.09e-01 100.0% 87.3%
8fbnB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.75 66.0 4.37e-01 100.0% 26.1%
3l1nA01 6.10.140.790 Special › Helix non-globular › Helix Hairpins › 0.75 53.0 5.42e-01 94.4% 78.4%
1fs0G02 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.75 68.0 5.69e-01 100.0% 75.3%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.75 65.0 5.48e-01 100.0% 63.8%
7tj9A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.75 67.0 5.34e-01 100.0% 52.8%
1a36A04 1.10.132.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.74 65.0 4.54e-01 98.1% 31.4%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.74 64.0 4.71e-01 98.1% 41.4%
4nsmA00 6.10.250.2770 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.74 63.0 5.70e-01 98.1% 70.4%
1zhcA00 6.10.280.50 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 62.0 5.65e-01 100.0% 78.9%
3lphC00 6.10.140.630 Special › Helix non-globular › Helix Hairpins › 0.72 58.0 5.74e-01 90.7% 84.5%
1z0jB00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.72 56.0 5.78e-01 85.2% 96.1%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.72 61.0 3.78e-01 100.0% 54.2%
1pd3A00 1.10.287.230 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 55.0 5.54e-01 85.2% 85.2%
4ke2A00 6.10.140.1860 Special › Helix non-globular › Helix Hairpins › 0.71 61.0 4.21e-01 100.0% 93.9%
2p4vA01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.71 59.0 5.34e-01 94.4% 77.6%
3tp3A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.70 61.0 4.41e-01 96.3% 41.9%
7wgrA02 3.40.50.12470 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.70 51.0 3.24e-01 77.8% 100.0%
4petA01 3.40.190.170 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Bacterial extracellular solute-binding protein, family 7 0.70 58.0 3.89e-01 94.4% 76.7%
1wazA00 1.10.287.910 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › bacterial mercury transporter, merf 0.69 53.0 5.67e-01 83.3% 100.0%
3layF00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.69 58.0 5.26e-01 100.0% 76.9%
1p49A02 1.10.287.550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.68 54.0 5.32e-01 90.7% 93.2%
1hr5A00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.67 50.0 5.19e-01 79.6% 93.8%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.67 54.0 5.16e-01 100.0% 77.9%
5b1oA00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.67 49.0 4.68e-01 81.5% 73.8%
3fcnA00 1.20.1220.20 Mainly Alpha › Up-down Bundle › Malate Synthase G; Chain: A; Domain 4 › Uncharcterised protein PF01724 0.67 57.0 4.16e-01 100.0% 34.2%
2jdiH02 1.20.5.440 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain 0.66 48.0 5.24e-01 79.6% 100.0%
3f1iS00 1.20.5.1940 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.65 51.0 4.60e-01 90.7% 62.3%
2vx2G02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.65 46.0 4.60e-01 75.9% 76.4%
2e5yA02 1.20.5.440 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain 0.64 48.0 5.21e-01 83.3% 100.0%
1fp1D02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.63 55.0 3.57e-01 96.3% 26.0%
3tahA02 1.10.287.1770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 50.0 4.25e-01 87.0% 100.0%
2lf0A01 4.10.860.10 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain 0.62 52.0 5.07e-01 100.0% 86.7%
8b6jF01 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.62 49.0 4.66e-01 98.1% 76.1%
4m70B00 1.10.246.200 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain 0.61 48.0 4.01e-01 85.2% 50.5%
5c9gA02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.60 47.0 4.69e-01 92.6% 86.0%
4bzaA01 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.59 41.0 3.88e-01 74.1% 58.8%
7b9cA02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.57 43.0 2.60e-01 79.6% 18.9%
2yfqB01 1.10.8.1210 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.55 40.0 4.06e-01 75.9% 78.8%
ECOD (52)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3770414 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.83 75.0 5.95e-01 100.0% 61.0%
3491651 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.83 76.0 5.09e-01 100.0% 29.7%
3957435 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.83 76.0 5.72e-01 100.0% 45.0%
3878000 192.29.1.1 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.82 69.0 5.70e-01 92.6% 77.9%
5009506 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.81 72.0 5.76e-01 100.0% 51.4%
3916497 632.8.1.17 alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › Rab_eff_C 0.81 73.0 5.51e-01 100.0% 93.6%
4981709 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.81 69.0 5.05e-01 100.0% 36.4%
3315495 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.80 72.0 6.13e-01 98.1% 64.7%
4010706 1.1.7.98 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › PF25876 0.80 71.0 6.50e-01 100.0% 82.9%
4028999 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.79 70.0 6.58e-01 100.0% 81.5%
3646270 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.79 70.0 6.25e-01 100.0% 74.7%
3206884 109.10.1.1 alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.78 67.0 4.36e-01 96.3% 24.3%
3585224 192.29.1.1 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.77 68.0 5.85e-01 98.1% 64.7%
3401938 3602.1.1.14 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › DUF733 0.77 68.0 6.06e-01 98.1% 73.3%
3464325 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.77 63.0 5.46e-01 94.4% 58.8%
3934830 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.76 67.0 5.89e-01 98.1% 68.8%
3913986 192.1.1.36 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › BAG6 0.76 69.0 5.43e-01 98.1% 55.2%
3705545 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.76 65.0 4.61e-01 100.0% 41.1%
3853458 192.29.1.1 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.76 69.0 5.63e-01 100.0% 71.6%
3626992 632.8.1.2 alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › Alpha-2-MRAP_C 0.76 67.0 5.40e-01 100.0% 81.9%
3597950 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.75 66.0 4.16e-01 100.0% 19.6%
3258925 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.75 65.0 6.01e-01 98.1% 78.6%
3784740 3712.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 0.75 66.0 5.94e-01 100.0% 77.3%
3589720 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.75 68.0 4.88e-01 100.0% 81.4%
3271160 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.75 65.0 4.34e-01 100.0% 25.0%
2661271 192.29.1.1 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.74 64.0 6.06e-01 98.1% 84.6%
4001550 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.74 59.0 5.24e-01 85.2% 70.7%
4827920 4268.2.1.2 alpha duplicates or obligate multimers › EspA/CesA-like › EspA chaperone CesA › EspA chaperone CesA › Rx_N 0.74 62.0 5.61e-01 90.7% 71.8%
3780051 3602.1.1.0 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain 0.74 57.0 5.52e-01 81.5% 76.7%
4942736 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.74 63.0 5.16e-01 100.0% 51.4%
4817720 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.74 64.0 4.01e-01 100.0% 19.1%
3651322 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.74 66.0 4.04e-01 100.0% 21.8%
5055566 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.73 65.0 5.13e-01 100.0% 49.6%
3503594 192.8.1.391 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › EMC3_TMCO1 0.73 62.0 5.42e-01 98.1% 64.7%
3575178 616.1.1.30 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Neur_chan_memb 0.73 64.0 5.75e-01 98.1% 70.7%
3111731 5054.1.1.2 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans 0.72 65.0 4.03e-01 100.0% 18.9%
3477269 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.72 64.0 4.59e-01 100.0% 37.4%
3606270 4015.1.1.1 alpha complex topology › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › Sec1 0.72 57.0 3.70e-01 100.0% 18.8%
5072037 192.17.1.0 alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like 0.72 60.0 5.46e-01 90.7% 72.9%
3881428 3835.1.1.1 alpha bundles › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein › PLC-beta_C 0.72 61.0 4.24e-01 100.0% 28.4%
4928145 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.72 61.0 5.44e-01 100.0% 77.5%
3268134 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 62.0 3.68e-01 100.0% 12.4%
4942789 4323.1.1.0 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.71 63.0 4.63e-01 100.0% 41.4%
3519344 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.71 61.0 3.77e-01 100.0% 30.9%
3945620 5086.1.1.85 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AAEA_pHBA 0.71 62.0 5.26e-01 100.0% 92.2%
5048467 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.70 57.0 4.18e-01 88.9% 36.6%
3535523 1073.1.1.11 alpha arrays › Mitochondrial calcium uniporter (MCU) › Mitochondrial calcium uniporter (MCU) › Mitochondrial calcium uniporter (MCU) › WWC1 0.70 59.0 5.58e-01 100.0% 76.9%
5023625 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.70 58.0 4.70e-01 90.7% 71.0%
3287376 101.1.2.49 alpha arrays › HTH › HTH › winged helix domain › PadR,Vir_act_alpha_C 0.69 59.0 4.14e-01 98.1% 29.7%
3640760 3291.1.1.17 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › DUF202 0.68 58.0 4.72e-01 100.0% 49.1%
3286277 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.68 58.0 4.12e-01 100.0% 31.7%
4487102 706.1.1.1 beta complex topology › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE › GrpE 0.66 56.0 4.43e-01 94.4% 80.0%