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early_protein
Euk-VirMurmansk_poxvirus
early_protein__YP_009408239__Murmansk_poxvirus__2025359
Identity
- Accession:
- YP_009408239 ↗
- Protein ID:
- early_protein
- Kingdom:
- euk
Quality
87.7
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Centapoxvirus›
Murmansk_poxvirus
TaxID: 2025359
Cluster
View cluster (13 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 136-246
Domain cluster:
rep: MC036R__NP_043987__Molluscum_contagiosum_virus_subtype_1__10280__D824-918
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF10523.16 best | BEN | 27.2 | 5.20e-06 | 70.3% | 97.4% |
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7yugA01 | 1.10.10.2590 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › BEN domain | 0.76 | 68.0 | 6.81e-01 | 94.6% | 99.1% |
| 4nqwA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.62 | 29.0 | 3.72e-01 | 72.1% | 76.6% |
| 3ccyA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 46.0 | 4.25e-01 | 91.0% | 66.7% |
| 1sgmA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 44.0 | 3.76e-01 | 87.4% | 55.4% |
| 3dcfA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 41.0 | 3.84e-01 | 89.2% | 66.2% |
| 1rj1A00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.53 | 37.0 | 3.38e-01 | 73.0% | 91.9% |
| 2j3rB00 | 3.30.1380.20 | Alpha Beta › 2-Layer Sandwich › Muramoyl-pentapeptide Carboxypeptidase; domain 2 › Trafficking protein particle complex subunit 3 | 0.53 | 38.0 | 3.39e-01 | 74.8% | 71.3% |
| 1lm3B00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.51 | 36.0 | 3.66e-01 | 85.6% | 74.5% |
| 4ga4A01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.51 | 28.0 | 3.50e-01 | 81.1% | 88.1% |
| 1dqaD01 | 1.10.3270.10 | Mainly Alpha › Orthogonal Bundle › HMGR, N-terminal domain › HMGR, N-terminal domain | 0.51 | 27.0 | 3.50e-01 | 72.1% | 95.0% |
| 1tazA00 | 1.10.1300.10 | Mainly Alpha › Orthogonal Bundle › Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b › 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain | 0.51 | 43.0 | 3.18e-01 | 96.4% | 90.4% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3846256 | 101.1.1.53 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › BEN | 0.82 | 67.0 | 7.25e-01 | 91.0% | 100.0% |
| 3530628 | 101.1.1.53 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › BEN | 0.82 | 67.0 | 6.68e-01 | 88.3% | 83.5% |
| 3524498 | 101.1.1.53 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › BEN | 0.79 | 68.0 | 6.85e-01 | 91.9% | 91.8% |
| 3920858 | 101.1.1.53 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › BEN | 0.77 | 62.0 | 6.44e-01 | 86.5% | 100.0% |
| 3882062 | 101.1.1.53 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › BEN | 0.76 | 63.0 | 6.53e-01 | 91.9% | 94.3% |
| 3854525 | 101.1.1.53 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › BEN | 0.75 | 67.0 | 6.63e-01 | 95.5% | 97.4% |
| 3489446 | 101.1.1.416 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › DUF5725 | 0.74 | 63.0 | 6.29e-01 | 91.9% | 96.5% |
| 3910609 | 101.1.1.53 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › BEN | 0.73 | 62.0 | 5.95e-01 | 90.1% | 92.0% |
| 3498569 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.73 | 59.0 | 6.11e-01 | 91.0% | 91.4% |
| 3496487 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.72 | 61.0 | 5.93e-01 | 95.5% | 83.3% |
| 3926647 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.72 | 59.0 | 5.44e-01 | 88.3% | 73.6% |
| 3931911 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.71 | 60.0 | 5.96e-01 | 91.0% | 87.8% |
| 3937184 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.70 | 57.0 | 5.97e-01 | 87.4% | 99.0% |
| 3928152 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.69 | 57.0 | 5.29e-01 | 88.3% | 72.9% |
| 3220382 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.69 | 57.0 | 5.67e-01 | 88.3% | 87.8% |
| 3882554 | 101.1.1.53 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › BEN | 0.67 | 56.0 | 5.56e-01 | 89.2% | 100.0% |
| 3223918 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.67 | 57.0 | 5.21e-01 | 91.9% | 86.2% |
| 4955440 | 1079.1.1.0 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA | 0.62 | 46.0 | 3.87e-01 | 78.4% | 83.2% |
| 4568031 | 191.1.1.2 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_4 | 0.61 | 50.0 | 4.68e-01 | 88.3% | 80.0% |
| 4178594 | 191.1.1.50 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › SlmA-like_C | 0.58 | 47.0 | 4.27e-01 | 87.4% | 73.6% |
| 3974736 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.55 | 32.0 | 3.60e-01 | 91.0% | 75.3% |
| 3831168 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.54 | 41.0 | 3.79e-01 | 79.3% | 87.1% |
| 3294610 | 109.4.1.459 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › eIF3_p135 | 0.52 | 43.0 | 4.00e-01 | 91.9% | 88.3% |
| 3236856 | 174.1.1.50 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF7807 | 0.51 | 39.0 | 3.31e-01 | 79.3% | 66.3% |
| 4930376 | 3896.1.1.0 ↗ | alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase | 0.50 | 40.0 | 3.36e-01 | 87.4% | 87.0% |
D2
high
residues 248-350
Domain cluster:
rep: Hypothetical_protein_SPPV_32__NP_659608__Sheeppox_virus__10266__D260-357
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7yulA01 | 1.10.10.2590 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › BEN domain | 0.73 | 56.0 | 6.15e-01 | 80.6% | 98.8% |
| 4ix7A00 | 1.10.10.2590 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › BEN domain | 0.70 | 57.0 | 5.54e-01 | 86.4% | 80.7% |
| 3lcnB00 | 1.10.340.40 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain | 0.61 | 37.0 | 3.87e-01 | 100.0% | 63.9% |
| 3vbbE01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.61 | 27.0 | 2.63e-01 | 97.1% | 34.5% |
| 2rq1A00 | 1.20.80.10 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › | 0.55 | 36.0 | 3.54e-01 | 96.1% | 61.5% |
| 3go9A02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.54 | 40.0 | 3.13e-01 | 77.7% | 68.2% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3530628 | 101.1.1.53 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › BEN | 0.79 | 63.0 | 6.05e-01 | 83.5% | 78.3% |
| 3846256 | 101.1.1.53 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › BEN | 0.78 | 62.0 | 6.49e-01 | 83.5% | 95.8% |
| 4059601 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.74 | 58.0 | 6.19e-01 | 84.5% | 95.6% |
| 3907981 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.73 | 58.0 | 6.14e-01 | 84.5% | 96.7% |
| 3922008 | 101.1.1.97 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › DUF4806 | 0.72 | 55.0 | 5.51e-01 | 86.4% | 78.1% |
| 3393516 | 101.1.1.53 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › BEN | 0.71 | 55.0 | 5.36e-01 | 80.6% | 77.3% |
| 224085 | 101.1.1.53 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › BEN | 0.70 | 57.0 | 5.54e-01 | 86.4% | 80.7% |
| 3480927 | 101.1.1.53 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › BEN | 0.69 | 57.0 | 5.84e-01 | 87.4% | 90.0% |
| 3498569 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.69 | 57.0 | 5.74e-01 | 87.4% | 92.4% |
| 3489446 | 101.1.1.416 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › DUF5725 | 0.68 | 55.0 | 5.31e-01 | 85.4% | 98.3% |
| 3931911 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.67 | 52.0 | 5.09e-01 | 84.5% | 79.1% |
| 3542946 | 101.1.1.53 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › BEN | 0.65 | 56.0 | 5.11e-01 | 94.2% | 83.5% |
| 5076856 | 186.1.1.1 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_1 | 0.61 | 40.0 | 4.06e-01 | 100.0% | 66.7% |
| 5058594 | 219.1.1.13 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core | 0.54 | 48.0 | 3.87e-01 | 99.0% | 87.5% |
| 4150217 | 633.2.1.1 ↗ | alpha bundles › Bromodomain-like › Carnobacteriocin B2 immunity protein › Carnobacteriocin B2 immunity protein › EntA_Immun | 0.51 | 38.0 | 4.06e-01 | 100.0% | 91.1% |
| 3950478 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.51 | 28.0 | 3.25e-01 | 84.5% | 75.7% |
| 1687145 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.50 | 39.0 | 4.01e-01 | 83.5% | 92.9% |
D3
medium
residues 1-102
Domain cluster:
representative
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3h20A04 | 1.10.1240.50 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › | 0.62 | 43.0 | 4.61e-01 | 72.5% | 83.1% |
| 3w2zA00 | 3.30.450.40 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain | 0.62 | 44.0 | 3.68e-01 | 74.5% | 98.9% |
| 4gr2A00 | 1.10.1200.210 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Chaperonin-like RbcX | 0.61 | 42.0 | 4.13e-01 | 70.6% | 83.6% |
| 5kbwB00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.58 | 44.0 | 3.70e-01 | 79.4% | 74.3% |
| 2g3bA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 44.0 | 3.62e-01 | 83.3% | 71.7% |
| 3jamD02 | 3.30.1140.32 | Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Ribosomal protein S3, C-terminal domain | 0.56 | 39.0 | 3.60e-01 | 71.6% | 68.4% |
| 4ap2B01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.54 | 41.0 | 3.74e-01 | 87.3% | 60.4% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 50.0 | 3.97e-01 | 97.1% | 61.6% |
| 3vglA02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.54 | 39.0 | 3.34e-01 | 77.5% | 91.9% |
| 3crjC00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 42.0 | 3.55e-01 | 89.2% | 69.8% |
| 1rz4A01 | 1.25.40.250 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › ARM repeat; domain 1 | 0.51 | 40.0 | 3.76e-01 | 81.4% | 79.2% |
| 3lwjA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 42.0 | 3.50e-01 | 95.1% | 94.8% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3795528 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 41.0 | 4.07e-01 | 90.2% | 68.6% |
| 3728216 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.59 | 53.0 | 3.50e-01 | 100.0% | 51.7% |
| 3819225 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 52.0 | 4.68e-01 | 100.0% | 79.3% |
| 3337893 | 109.4.1.1444 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_14, TPR_16 | 0.56 | 52.0 | 3.79e-01 | 100.0% | 41.1% |
| 3530780 | 310.2.1.2 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › MIX23 | 0.55 | 40.0 | 3.70e-01 | 78.4% | 59.2% |
| 3423804 | 109.4.1.202 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_16 | 0.55 | 42.0 | 4.12e-01 | 81.4% | 87.3% |
| 3621308 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.54 | 41.0 | 3.40e-01 | 79.4% | 87.4% |
| 3819983 | 109.4.1.1207 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_TmcB | 0.54 | 50.0 | 4.63e-01 | 100.0% | 87.2% |
| 3383724 | 109.4.1.210 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 | 0.52 | 45.0 | 4.24e-01 | 100.0% | 89.2% |
| 3667435 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 29.0 | 2.82e-01 | 73.5% | 45.8% |
| 4504172 | 101.35.1.0 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX | 0.51 | 39.0 | 3.88e-01 | 85.3% | 81.0% |
| 3518335 | 109.4.1.142 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CSN8_PSD8_EIF3K | 0.50 | 38.0 | 3.85e-01 | 84.3% | 88.6% |