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early_transcription_factor_large_subunit

Euk-Vir

Marseillevirus_marseillevirus

early_transcription_factor_large_subunit__YP_003407040__Marseillevirus_marseillevirus__694581

Identity

Accession:
YP_003407040 ↗
Protein ID:
early_transcription_factor_large_subunit
Kingdom:
euk

Quality

45.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 439-533
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF19061.6 best DUF5757 51.0 2.10e-13 84.2% 84.4%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2pt7G02 3.30.1370.180 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.63 25.0 2.98e-01 95.8% 52.2%
1earA02 3.30.70.790 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › UreE, C-terminal domain 0.54 33.0 3.69e-01 88.4% 82.6%
2yilA02 3.30.30.180 Alpha Beta › 2-Layer Sandwich › Defensin A-like › 0.54 22.0 2.85e-01 88.4% 64.7%
2a1vA00 3.90.1150.30 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.53 39.0 3.49e-01 76.8% 66.7%
2fyfA02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.52 37.0 3.68e-01 76.8% 74.3%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4518870 320.2.1.1 a+b two layers › R3H domain-like › Ribosomal protein S8, N-terminal domain › Ribosomal protein S8, N-terminal domain › Ribosomal_S8 0.54 28.0 3.25e-01 73.7% 70.8%
5024525 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.53 28.0 3.43e-01 97.9% 85.5%
5041633 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.50 29.0 3.26e-01 84.2% 75.7%
D2 medium residues 547-591_678-746_763-800
PDB
D3 medium residues 592-677
PDB
Domain cluster: representative
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4bopB00 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.77 62.0 5.17e-01 100.0% 50.7%
3tmpA01 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.75 61.0 5.06e-01 100.0% 50.7%
5jzeA00 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.72 62.0 5.04e-01 100.0% 50.9%
3by4A00 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.72 59.0 4.69e-01 100.0% 44.2%
7pl7A01 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.69 61.0 5.09e-01 100.0% 57.9%
1qrvA00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.60 35.0 3.80e-01 87.2% 68.5%
3ee4A00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.60 42.0 2.91e-01 73.3% 62.3%
2hinA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.57 35.0 3.83e-01 90.7% 78.8%
1hr6A01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.55 42.0 3.18e-01 81.4% 59.3%
2v5cA03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.55 38.0 3.35e-01 72.1% 51.5%
3vayA02 1.20.120.1600 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.54 35.0 3.52e-01 97.7% 64.4%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.51 37.0 3.21e-01 76.7% 61.5%
2n3eA01 1.10.274.70 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain 0.51 39.0 3.60e-01 83.7% 80.0%
4xk2B00 3.20.20.100 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › NADP-dependent oxidoreductase domain 0.51 39.0 2.76e-01 86.0% 35.3%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.50 41.0 3.72e-01 93.0% 87.2%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3401495 219.1.1.15 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › OTU 0.78 63.0 5.08e-01 100.0% 46.1%
3430148 219.1.1.15 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › OTU 0.76 68.0 5.65e-01 100.0% 58.0%
4020266 219.1.1.15 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › OTU 0.71 63.0 5.00e-01 100.0% 51.1%
3729552 219.1.1.15 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › OTU 0.67 60.0 5.01e-01 100.0% 68.7%
3166149 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.62 46.0 3.51e-01 80.2% 93.8%
3896445 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.59 45.0 3.26e-01 80.2% 72.9%
5076610 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.59 45.0 3.35e-01 81.4% 82.7%
5022207 1075.3.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 0.58 43.0 3.15e-01 77.9% 74.3%
3500625 604.39.1.17 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › DUF2238 0.56 43.0 3.58e-01 83.7% 79.4%
3415759 622.1.1.1 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HSCB_C 0.54 35.0 3.56e-01 86.0% 67.1%
5065286 129.1.1.0 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like 0.53 39.0 3.56e-01 77.9% 81.6%
3311490 622.1.1.1 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HSCB_C 0.53 35.0 3.52e-01 86.0% 67.1%
4099493 622.1.1.1 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HSCB_C 0.51 34.0 3.28e-01 86.0% 60.0%
3708768 3711.1.1.0 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.51 37.0 3.34e-01 75.6% 96.7%
3721575 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.51 34.0 3.42e-01 100.0% 69.4%