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envelope_glycoprotein_B
Euk-VirBovine_alphaherpesvirus_1
envelope_glycoprotein_B__NP_045331__Bovine_alphaherpesvirus_1__10320
Identity
- Accession:
- NP_045331 ↗
- Protein ID:
- envelope_glycoprotein_B
- Kingdom:
- euk
Quality
68.3
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Varicellovirus›
bovine_alphaherpesvirus_1
TaxID: 10320
Cluster
View cluster (34 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 109-128_607-695
Domain cluster:
rep: envelope_glycoprotein_B__YP_009342376__Spheniscid_alphaherpesvirus_1__2560777__D566-653
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00606.24 best | Glycoprotein_B | 99.3 | 3.30e-28 | 93.6% | 40.5% |
D2
medium
residues 146-165_384-422_534-575
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00606.24 best | Glycoprotein_B | 48.6 | 1.00e-12 | 41.6% | 18.5% |
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4zudA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 40.0 | 2.94e-01 | 96.0% | 26.2% |
| 3ottB02 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.57 | 45.0 | 3.21e-01 | 86.1% | 67.4% |
| 6grrB01 | 3.30.457.10 | Alpha Beta › 2-Layer Sandwich › Copper Amine Oxidase; Chain A, domain 1 › Copper amine oxidase-like, N-terminal domain | 0.56 | 35.0 | 3.94e-01 | 74.3% | 82.3% |
| 1fblA02 | 2.110.10.10 | Mainly Beta › 4 Propeller › Hemopexin › Hemopexin-like domain | 0.54 | 43.0 | 3.52e-01 | 85.1% | 91.1% |
| 1yqfB00 | 3.10.280.10 | Alpha Beta › Roll › Mitochondrial Matrix Protein; Chain A › Mitochondrial glycoprotein | 0.53 | 45.0 | 3.75e-01 | 94.1% | 76.8% |
| 3ed4A02 | 3.30.1120.10 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › | 0.52 | 38.0 | 4.11e-01 | 82.2% | 95.2% |
| 5hy7B01 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.52 | 43.0 | 2.88e-01 | 91.1% | 88.3% |
| 1ek9A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.51 | 47.0 | 3.04e-01 | 100.0% | 55.1% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3650120 | 219.1.1.0 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases | 0.63 | 42.0 | 3.00e-01 | 100.0% | 23.9% |
| 3899940 | 331.4.1.9 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › CPSF73-100_C | 0.58 | 34.0 | 3.78e-01 | 73.3% | 73.8% |
| 3254112 | 5.1.3.4 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › WD40 | 0.56 | 46.0 | 3.15e-01 | 91.1% | 93.0% |
| 3521876 | 5.1.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 4-bladed › Hemopexin | 0.55 | 43.0 | 3.48e-01 | 86.1% | 85.4% |
| 3854218 | 5.1.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 4-bladed › Hemopexin | 0.54 | 43.0 | 3.51e-01 | 86.1% | 87.9% |
| 3175626 | 331.1.1.13 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › CPSF73-100_C | 0.54 | 32.0 | 3.64e-01 | 73.3% | 78.7% |
| 3779915 | 5.1.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 4-bladed › Hemopexin | 0.54 | 42.0 | 3.39e-01 | 84.2% | 83.9% |
| 4046039 | 318.1.1.1 ↗ | a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal_L6 | 0.54 | 28.0 | 3.03e-01 | 91.1% | 60.0% |
| 3448051 | 5.1.3.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed | 0.54 | 46.0 | 3.59e-01 | 99.0% | 98.8% |
| 3969662 | 5085.1.1.1 ↗ | a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP | 0.52 | 47.0 | 3.12e-01 | 100.0% | 25.4% |
| 3483693 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.52 | 32.0 | 2.95e-01 | 76.2% | 48.5% |
| 3396749 | 5.1.5.73 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › PEP5_VPS11_N | 0.52 | 41.0 | 2.96e-01 | 90.1% | 81.4% |
| 4994522 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.51 | 47.0 | 4.00e-01 | 100.0% | 88.1% |
| 3925754 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.51 | 47.0 | 4.25e-01 | 100.0% | 88.1% |
| 3935357 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.51 | 45.0 | 4.26e-01 | 94.1% | 95.8% |
| 3929729 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.51 | 45.0 | 3.64e-01 | 97.0% | 56.4% |
| 3171576 | 247.1.1.38 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › CPSF73-100_C | 0.51 | 31.0 | 3.48e-01 | 73.3% | 77.5% |
D3
medium
residues 166-286
Domain cluster:
rep: envelope_glycoprotein_B__YP_009344884__Murine_roseolovirus__1940555__D81-138_150-207
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF17416.9 best | Glycoprot_B_PH1 | 126.6 | 1.50e-36 | 100.0% | 57.6% |
D4
medium
residues 287-370_726-747
Domain cluster:
rep: Glycoprotein_B__YP_214067__Murid_betaherpesvirus_1__10366__D277-316_330-353
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF17416.9 best | Glycoprot_B_PH1 | 93.9 | 1.50e-26 | 83.0% | 39.5% |
D5
medium
residues 371-383_423-483
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF17417.9 best | Glycoprot_B_PH2 | 53.5 | 3.50e-14 | 87.8% | 61.9% |
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2gumB03 | 2.30.29.100 | Mainly Beta › Roll › PH-domain like › | 0.97 | 79.0 | 6.45e-01 | 83.8% | 82.6% |
| 4osnA00 | 2.30.29.100 | Mainly Beta › Roll › PH-domain like › | 0.92 | 69.0 | 5.86e-01 | 77.0% | 86.4% |
| 3fvcA03 | 2.30.29.100 | Mainly Beta › Roll › PH-domain like › | 0.91 | 69.0 | 5.86e-01 | 78.4% | 87.3% |
| 2d42A02 | 3.10.450.380 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.70 | 44.0 | 4.69e-01 | 70.3% | 72.3% |
| 6le1A01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.64 | 40.0 | 4.16e-01 | 70.3% | 67.6% |
| 3w1hA01 | 3.90.1150.110 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › | 0.63 | 43.0 | 3.20e-01 | 70.3% | 34.9% |
| 6urtA02 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.61 | 42.0 | 3.99e-01 | 77.0% | 60.2% |
| 2qdfA02 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.58 | 40.0 | 3.92e-01 | 74.3% | 98.8% |
| 4k3bA02 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.57 | 42.0 | 4.10e-01 | 79.7% | 100.0% |
| 3aqpA02 | 3.30.70.3220 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 34.0 | 2.70e-01 | 74.3% | 26.9% |
| 1pu1A00 | 3.30.300.100 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like | 0.56 | 43.0 | 4.05e-01 | 82.4% | 68.1% |
| 2onfA01 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.54 | 42.0 | 3.52e-01 | 86.5% | 59.7% |
| 3ce8A00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.53 | 42.0 | 3.96e-01 | 86.5% | 91.0% |
| 3nqzA02 | 3.10.450.40 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.53 | 39.0 | 3.77e-01 | 79.7% | 72.6% |
| 3viqA00 | 6.10.140.1020 | Special › Helix non-globular › Helix Hairpins › | 0.52 | 30.0 | 2.63e-01 | 100.0% | 32.8% |
| 5ib9A01 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.52 | 40.0 | 2.76e-01 | 85.1% | 51.2% |
| 3wa7A00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.51 | 36.0 | 2.25e-01 | 74.3% | 34.3% |
| 2d7vB00 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.51 | 39.0 | 3.19e-01 | 85.1% | 55.6% |
| 2mp4A00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.50 | 38.0 | 2.99e-01 | 82.4% | 38.2% |
| 2pn2A00 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.50 | 38.0 | 3.18e-01 | 82.4% | 63.5% |
| 2v8qA01 | 3.30.310.80 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 | 0.50 | 37.0 | 3.56e-01 | 79.7% | 77.5% |
| 4gs5A02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.50 | 41.0 | 3.67e-01 | 90.5% | 81.9% |
| 1vwxP00 | 3.90.470.10 | Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Ribosomal protein L22/L17 | 0.50 | 39.0 | 3.12e-01 | 83.8% | 86.3% |
ECOD (32)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3932886 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.71 | 48.0 | 4.42e-01 | 74.3% | 54.7% |
| 3924669 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.71 | 46.0 | 4.28e-01 | 75.7% | 52.6% |
| 4028722 | 304.16.1.1 ↗ | a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE | 0.69 | 43.0 | 3.66e-01 | 75.7% | 37.6% |
| 4595166 | 5076.2.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ | 0.66 | 36.0 | 2.53e-01 | 79.7% | 16.9% |
| 3268432 | 109.4.1.1208 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ABC1 | 0.65 | 41.0 | 3.01e-01 | 74.3% | 24.1% |
| 4976198 | 878.1.1.1 ↗ | a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 | 0.64 | 45.0 | 4.34e-01 | 83.8% | 64.7% |
| 5035423 | 295.1.1.0 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain | 0.60 | 38.0 | 3.62e-01 | 74.3% | 55.3% |
| 4534145 | 3016.1.1.11 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › SelA | 0.60 | 44.0 | 3.89e-01 | 78.4% | 56.4% |
| 4233442 | 304.4.1.54 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Amnionless | 0.59 | 41.0 | 3.55e-01 | 81.1% | 45.0% |
| 3943661 | 304.5.1.13 ↗ | a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF3574 | 0.59 | 42.0 | 3.84e-01 | 74.3% | 60.0% |
| 1824189 | 327.6.1.3 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Fe-S cluster assembly (FSCA) domain-like › Fe-S cluster assembly (FSCA) domain-like › Germane | 0.57 | 42.0 | 3.36e-01 | 78.4% | 57.7% |
| 4948264 | 878.1.1.1 ↗ | a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 | 0.56 | 40.0 | 3.97e-01 | 85.1% | 71.2% |
| 3268288 | 5001.1.1.5 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 | 0.56 | 39.0 | 2.68e-01 | 73.0% | 40.0% |
| 4968960 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.56 | 45.0 | 3.26e-01 | 90.5% | 78.3% |
| 4240079 | 304.4.1.4 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM | 0.56 | 36.0 | 3.30e-01 | 77.0% | 48.0% |
| 5078624 | 878.1.1.1 ↗ | a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 | 0.55 | 41.0 | 3.71e-01 | 81.1% | 58.1% |
| 3593808 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.54 | 37.0 | 3.38e-01 | 71.6% | 84.0% |
| 3928059 | 327.11.2.14 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_9 | 0.54 | 35.0 | 3.32e-01 | 73.0% | 53.3% |
| 3268232 | 304.109.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ribosomal proteins S24e, L23 and L15e › Ribosomal proteins S24e, L23 and L15e | 0.54 | 43.0 | 3.78e-01 | 91.9% | 65.8% |
| 4809699 | 3781.1.1.1 ↗ | a+b two layers › Ribosomal protein L11/L12e N-terminal domain-like › Ribosomal protein L11/L12e N-terminal domain › Ribosomal protein L11/L12e N-terminal domain › Ribosomal_L11_N | 0.54 | 39.0 | 4.07e-01 | 93.2% | 87.7% |
| 4994610 | 512.1.1.2 ↗ | a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_2nd | 0.54 | 39.0 | 3.47e-01 | 79.7% | 62.6% |
| 3241453 | 2484.1.1.233 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF1280 | 0.53 | 38.0 | 2.55e-01 | 77.0% | 24.4% |
| 3224634 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.53 | 38.0 | 2.51e-01 | 78.4% | 32.2% |
| 3786528 | 109.4.1.87 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec6 | 0.52 | 45.0 | 2.59e-01 | 100.0% | 38.3% |
| 3249830 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.52 | 38.0 | 3.24e-01 | 82.4% | 46.4% |
| 3778175 | 5052.1.1.1 ↗ | alpha complex topology › Proton glutamate symport protein › Proton glutamate symport protein › Proton glutamate symport protein › SDF | 0.52 | 38.0 | 2.36e-01 | 78.4% | 29.6% |
| 3194847 | 3343.1.1.2 ↗ | alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal | 0.51 | 38.0 | 2.30e-01 | 82.4% | 13.8% |
| 4004108 | 273.1.1.1 ↗ | a+b three layers › PR-1-like › PR-1-like › PR-1-like › CAP | 0.51 | 42.0 | 2.97e-01 | 93.2% | 71.2% |
| 4233683 | 171.1.1.1 ↗ | alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 | 0.51 | 40.0 | 2.96e-01 | 89.2% | 84.5% |
| 5057424 | 177.1.1.0 ↗ | alpha bundles › Phospholipase C/P1 nuclease › Phospholipase C/P1 nuclease › Phospholipase C/P1 nuclease | 0.51 | 34.0 | 2.51e-01 | 70.3% | 56.4% |
| 3636298 | 5001.1.1.6 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Bac_rhodopsin | 0.50 | 43.0 | 3.07e-01 | 97.3% | 92.5% |
| 4160692 | 171.1.1.1 ↗ | alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 | 0.50 | 38.0 | 2.81e-01 | 85.1% | 87.6% |