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envelope_glycoprotein_B

Euk-Vir

Cercopithecine_alphaherpesvirus_9

envelope_glycoprotein_B__NP_077446__Cercopithecine_alphaherpesvirus_9__35246

Identity

Accession:
NP_077446 ↗
Protein ID:
envelope_glycoprotein_B
Kingdom:
euk

Quality

68.9 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Varicellovirus› Cercopithecine_alphaherpesvirus_9

TaxID: 35246

Cluster

View cluster (34 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 143-154_365-471
PDB
Domain cluster: rep: BALF4__YP_010084703__Lymphocryptovirus_Macaca_pfe-lcl-E3__1716044__D77-88_295-391
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17417.9 best Glycoprot_B_PH2 116.9 5.80e-34 82.3% 100.0%
D2 high residues 575-665
PDB
Domain cluster: rep: envelope_glycoprotein_B__YP_009342376__Spheniscid_alphaherpesvirus_1__2560777__D566-653
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00606.24 best Glycoprotein_B 104.3 9.80e-30 98.9% 37.8%
D3 medium residues 111-126_538-574
PDB
Domain cluster: representative
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gumA02 1.20.5.1890 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.96 79.0 6.17e-01 86.8% 100.0%
3fvcA02 1.20.5.1890 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.89 71.0 5.63e-01 84.9% 100.0%
4hziB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 43.0 2.82e-01 73.6% 23.3%
2ihyA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 43.0 2.82e-01 73.6% 23.0%
2pq0A02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.59 39.0 3.18e-01 77.4% 36.0%
1i2vA00 3.30.30.10 Alpha Beta › 2-Layer Sandwich › Defensin A-like › Knottin, scorpion toxin-like 0.58 40.0 4.27e-01 73.6% 100.0%
7k98E03 3.30.56.10 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › 0.58 41.0 3.79e-01 75.5% 64.7%
3pcoB04 3.30.56.10 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › 0.57 41.0 3.70e-01 77.4% 60.0%
1whvA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.57 42.0 3.48e-01 81.1% 43.0%
6lcqA00 3.30.30.10 Alpha Beta › 2-Layer Sandwich › Defensin A-like › Knottin, scorpion toxin-like 0.56 43.0 4.33e-01 86.8% 90.7%
6vudA02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.56 40.0 3.62e-01 77.4% 58.7%
2cxiA03 3.30.56.10 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › 0.56 44.0 4.01e-01 86.8% 67.1%
3ofgB00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.55 43.0 3.66e-01 86.8% 64.4%
6u9hF02 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.54 37.0 3.29e-01 77.4% 49.4%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.54 38.0 2.76e-01 77.4% 70.1%
2amyA02 3.30.1240.20 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › Eukaryotic phosphomannomutase, cap domain 0.54 39.0 3.21e-01 79.2% 59.8%
2w01B00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.54 38.0 2.65e-01 77.4% 29.9%
4ymhD00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 38.0 2.51e-01 77.4% 28.6%
3dnpA02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.53 37.0 2.96e-01 77.4% 35.4%
3aqoA01 3.30.70.3400 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 38.0 3.38e-01 77.4% 62.5%
3va7A05 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.53 38.0 3.13e-01 77.4% 53.0%
1in0A01 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 38.0 3.54e-01 83.0% 60.0%
7m0oA02 3.65.10.10 Alpha Beta › Alpha-beta prism › UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain › Enolpyruvate transferase domain 0.52 37.0 2.63e-01 77.4% 23.9%
7xhzA01 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.52 38.0 2.95e-01 79.2% 35.8%
1lfwA03 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 37.0 3.19e-01 77.4% 46.6%
1gx5A03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.52 40.0 3.18e-01 88.7% 51.6%
4qmfD02 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.51 39.0 3.35e-01 86.8% 60.9%
3zieD00 3.30.110.150 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › SepF-like protein 0.51 36.0 3.23e-01 77.4% 57.3%
1lxjA00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 36.0 2.99e-01 77.4% 44.7%
3pgvA02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.51 36.0 3.03e-01 79.2% 42.6%
ECOD (40)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2488247 4300.1.1.1 ↗ beta complex topology › Viral glycoprotein ectodomain-like › Viral glycoprotein ectodomain-like › Viral glycoprotein ectodomain-like › Glycoprotein_B 0.94 87.0 5.75e-01 100.0% 42.8%
3287096 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.63 44.0 2.80e-01 73.6% 20.7%
1109321 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.62 43.0 2.82e-01 73.6% 23.3%
3839210 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.59 43.0 2.76e-01 75.5% 22.0%
4950627 4081.1.1.0 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related 0.57 40.0 3.05e-01 77.4% 37.5%
5001157 304.120.1.6 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer 0.56 39.0 3.40e-01 73.6% 61.2%
2754912 242.1.1.2 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_2 0.56 41.0 3.27e-01 79.2% 54.6%
4957290 306.2.1.3 ↗ a+b two layers › Glucose permease domain IIB-like › arginine repressor C terminal domain-related › C-terminal domain of arginine repressor › DEAD_assoc 0.55 40.0 3.11e-01 77.4% 40.0%
3953697 305.2.1.1 ↗ a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.54 39.0 3.25e-01 77.4% 47.4%
3667726 242.1.1.2 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_2 0.54 39.0 3.22e-01 77.4% 41.0%
4956396 309.1.1.15 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › DEAD_assoc 0.53 38.0 2.70e-01 77.4% 25.6%
3056435 3016.1.1.0 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.53 38.0 3.10e-01 79.2% 50.9%
5033558 304.120.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI 0.53 38.0 3.53e-01 77.4% 62.9%
3594603 3012.1.1.0 ↗ a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.53 38.0 3.19e-01 79.2% 61.0%
4941634 306.3.1.6 ↗ a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › DEAD_assoc 0.53 37.0 3.02e-01 77.4% 40.0%
5027824 304.8.1.10 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_7 0.53 41.0 3.56e-01 86.8% 57.6%
4234725 304.28.1.4 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st 0.53 41.0 3.42e-01 86.8% 64.2%
5011633 3012.1.1.0 ↗ a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.52 38.0 3.13e-01 79.2% 43.3%
3619798 3122.1.1.1 ↗ a+b complex topology › MESD › MESD › MESD › Mesd 0.52 42.0 3.21e-01 90.6% 66.2%
4948690 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.52 37.0 2.33e-01 77.4% 13.6%
3164039 304.14.1.1 ↗ a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR 0.52 38.0 3.45e-01 79.2% 73.0%
4519248 327.11.2.0 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.52 38.0 3.97e-01 81.1% 100.0%
4932304 309.1.1.15 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › DEAD_assoc 0.52 37.0 2.65e-01 77.4% 26.3%
4937975 306.3.1.6 ↗ a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › DEAD_assoc 0.52 37.0 3.01e-01 79.2% 44.3%
5042968 304.120.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI 0.52 36.0 3.47e-01 75.5% 66.2%
4934435 309.1.1.15 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › DEAD_assoc 0.52 37.0 2.91e-01 79.2% 36.2%
3604140 242.1.1.7 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.52 38.0 2.68e-01 81.1% 25.9%
5040317 309.1.1.15 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › DEAD_assoc 0.52 37.0 2.64e-01 79.2% 25.4%
3706636 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.52 36.0 3.28e-01 77.4% 53.8%
3839295 3012.1.1.0 ↗ a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.51 37.0 3.45e-01 79.2% 61.4%
5031915 242.1.1.0 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.51 35.0 3.14e-01 75.5% 54.1%
3927851 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.51 37.0 3.05e-01 79.2% 59.0%
5029570 305.2.1.1 ↗ a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.51 36.0 3.08e-01 77.4% 46.3%
5057396 304.3.1.0 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.51 37.0 3.37e-01 83.0% 56.0%
3594539 3012.1.1.0 ↗ a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.51 36.0 2.92e-01 75.5% 78.1%
4948745 2006.1.1.3 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Trehalose_PPase 0.51 37.0 2.43e-01 81.1% 37.0%
4982161 309.1.1.15 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › DEAD_assoc 0.51 36.0 2.80e-01 77.4% 34.1%
3639504 305.2.1.1 ↗ a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.51 36.0 2.92e-01 77.4% 40.0%
4049326 328.6.1.1 ↗ a+b two layers › IF3-like › EPT/RTPC-like › EPT/RTPC-like › EPSP_synthase 0.51 37.0 2.44e-01 77.4% 25.8%
4011314 3012.1.1.0 ↗ a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.50 36.0 3.26e-01 79.2% 62.5%
D4 medium residues 155-165_276-364
PDB
Domain cluster: rep: Glycoprotein_B__YP_214067__Murid_betaherpesvirus_1__10366__D277-316_330-353
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17416.9 best Glycoprot_B_PH1 103.7 1.60e-29 95.0% 43.8%
D5 medium residues 166-275
PDB
Domain cluster: rep: envelope_glycoprotein_B__YP_009344884__Murine_roseolovirus__1940555__D81-138_150-207
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17416.9 best Glycoprot_B_PH1 120.8 9.40e-35 100.0% 51.9%