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envelope_glycoprotein_H

Euk-Vir

Gallid_alphaherpesvirus_3

envelope_glycoprotein_H__NP_066853__Gallid_alphaherpesvirus_3__35250

Identity

Accession:: NP_066853 ↗
Protein ID:: envelope_glycoprotein_H
Kingdom:: euk

Quality

74.2 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Mardivirus› Gallid_alphaherpesvirus_3

TaxID: 35250

Cluster

View cluster (30 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 391-502

PDB

Domain cluster: rep: envelope_glycoprotein_H__NP_045257__Equid_alphaherpesvirus_4__10331__D432-555

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02489.22 best	Herpes_glycop_H	40.6	2.00e-10	100.0%	19.8%

CATH (24)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2jqqA00	1.20.58.1240	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.70	61.0	5.54e-01	96.4%	86.4%
3ebbA00	1.25.10.10	Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant	0.68	61.0	4.63e-01	98.2%	42.8%
4epzA00	1.25.40.810	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ	0.66	51.0	4.66e-01	100.0%	60.4%
1o5hA00	1.20.120.680	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle	0.65	54.0	4.47e-01	89.3%	74.5%
4i17A00	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.63	56.0	4.48e-01	99.1%	57.1%
3vibA00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.61	47.0	3.94e-01	82.1%	62.2%
2b1eA02	1.20.1310.30	Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like ›	0.61	50.0	4.58e-01	91.1%	98.0%
3kflA03	1.10.730.10	Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1	0.59	44.0	3.85e-01	78.6%	68.0%
2ebfX02	1.20.140.180	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 ›	0.58	39.0	3.66e-01	74.1%	53.1%
2ygwA01	1.20.140.90	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Malonyl-CoA decarboxylase, oligemerization domain	0.58	51.0	4.68e-01	99.1%	99.3%
2pziA04	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.58	50.0	4.36e-01	99.1%	61.6%
2v0cA04	1.10.730.10	Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1	0.57	42.0	3.74e-01	92.0%	53.5%
1t33A02	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.56	42.0	3.76e-01	77.7%	71.5%
4a64C03	1.20.1310.10	Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats	0.56	45.0	4.70e-01	87.5%	100.0%
3mx3A01	1.25.40.390	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.55	46.0	3.91e-01	95.5%	72.7%
4wqoD00	1.20.1310.10	Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats	0.54	48.0	4.46e-01	98.2%	92.2%
3rmgA00	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.54	45.0	3.30e-01	90.2%	39.1%
2incB00	1.10.620.20	Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A	0.54	48.0	3.46e-01	99.1%	65.8%
2wzkA03	1.20.1310.10	Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats	0.53	45.0	4.61e-01	92.9%	94.5%
5j1hA01	1.20.58.1060	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.53	45.0	3.82e-01	92.0%	78.6%
5nohA00	1.20.120.1350	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain	0.51	31.0	3.22e-01	79.5%	64.1%
2rldA00	1.20.1440.60	Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence	0.51	39.0	3.93e-01	80.4%	90.4%
6z0fA02	1.25.40.680	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type VII secretion system EssB, C-terminal-like domain	0.51	46.0	4.04e-01	100.0%	68.7%
4fx0A00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.50	33.0	3.23e-01	99.1%	60.7%

ECOD (30)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4391257	109.4.1.356 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans	0.79	72.0	4.74e-01	100.0%	27.5%
4018727	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.75	68.0	5.54e-01	99.1%	68.3%
3687769	109.4.1.356 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans	0.73	67.0	4.42e-01	100.0%	32.6%
3867624	109.4.1.3415 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28426	0.70	62.0	4.73e-01	98.2%	51.7%
4030604	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.68	49.0	4.18e-01	78.6%	45.9%
3404235	6155.1.1.1 ↗	alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv	0.67	49.0	4.74e-01	75.9%	78.4%
3789688	6155.1.1.0 ↗	alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter	0.67	50.0	4.86e-01	78.6%	76.0%
3711015	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.66	60.0	4.67e-01	100.0%	81.7%
3560153	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.66	59.0	4.67e-01	100.0%	51.1%
3785328	109.4.1.356 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans	0.66	57.0	3.85e-01	99.1%	39.6%
3237006	6155.1.1.1 ↗	alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv	0.65	48.0	4.81e-01	77.7%	86.1%
3245201	6155.1.1.1 ↗	alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv	0.65	48.0	4.51e-01	77.7%	70.7%
3932453	6155.1.1.1 ↗	alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv	0.65	47.0	4.71e-01	75.9%	85.2%
3426712	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.65	52.0	4.17e-01	96.4%	45.2%
3993135	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.64	46.0	3.83e-01	74.1%	84.1%
3724669	109.4.1.356 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans	0.63	56.0	3.74e-01	100.0%	27.6%
154429	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.63	56.0	4.48e-01	99.1%	57.1%
3934009	109.4.1.2150 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RTP1_C2, RTP1_C1, ARM_TANGO6	0.62	56.0	3.28e-01	100.0%	37.0%
3927027	3922.1.1.244 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Otopetrin	0.61	45.0	3.43e-01	77.7%	64.0%
3724504	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.60	53.0	4.44e-01	100.0%	69.0%
3712140	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.60	53.0	3.81e-01	100.0%	45.5%
3477207	4320.1.1.1 ↗	alpha superhelices › Taf5 N-terminal domain-like › Taf5 N-terminal domain-like › Taf5 N-terminal domain-like › TFIID_NTD2	0.59	44.0	3.72e-01	79.5%	46.7%
3388223	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.59	40.0	3.91e-01	99.1%	64.2%
3412239	603.1.1.104 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › 7tm_7	0.58	51.0	3.62e-01	98.2%	95.6%
3280116	109.4.1.212 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_20	0.54	48.0	4.53e-01	100.0%	86.4%
3929097	4163.1.1.0 ↗	alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like	0.53	47.0	4.51e-01	99.1%	96.9%
3601554	4121.1.1.0 ↗	a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like	0.53	47.0	3.97e-01	99.1%	81.6%
3624667	5001.1.1.63 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab	0.52	42.0	3.06e-01	86.6%	59.7%
3392591	604.1.1.124 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_6	0.51	40.0	3.21e-01	83.9%	81.3%
3515022	109.4.1.192 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8	0.51	44.0	3.88e-01	100.0%	66.7%

D2 medium residues 159-178_275-389

PDB

Domain cluster: rep: envelope_glycoprotein_H__YP_068353__Suid_alphaherpesvirus_1__10345__D240-339

D3 medium residues 179-274

PDB

Domain cluster: rep: envelope_glycoprotein_H__YP_010087581__Cervid_alphaherpesvirus_3__2115790__D207-328

D4 medium residues 505-624

PDB

Domain cluster: rep: envelope_glycoprotein_H__NP_045337__Bovine_alphaherpesvirus_1__10320__D538-631

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02489.22 best	Herpes_glycop_H	34.7	1.20e-08	87.5%	10.0%

D5 medium residues 625-780

PDB

Domain cluster: rep: UL22__YP_003084400__Anatid_alphaherpesvirus_1__104388__D647-783

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF17488.8 best	Herpes_glycoH_C	96.9	1.20e-27	84.0%	90.1%