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envelope_glycoprotein_H

Euk-Vir

Cercopithecine_alphaherpesvirus_9

envelope_glycoprotein_H__NP_077452__Cercopithecine_alphaherpesvirus_9__35246

Identity

Accession:
NP_077452 ↗
Protein ID:
envelope_glycoprotein_H
Kingdom:
euk

Quality

72.2 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 341-432
PDB
CATH (42)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ix5A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.81 58.0 4.79e-01 73.9% 52.3%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.81 59.0 6.46e-01 90.2% 94.6%
4od4A02 1.20.120.1780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase 0.81 66.0 6.03e-01 87.0% 78.2%
4dmvA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.80 56.0 5.78e-01 87.0% 77.6%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.80 67.0 6.17e-01 90.2% 82.1%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.80 66.0 6.29e-01 89.1% 86.9%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.77 64.0 6.34e-01 89.1% 91.6%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.76 63.0 5.77e-01 88.0% 78.6%
1owaA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 63.0 6.01e-01 89.1% 91.5%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.76 63.0 5.80e-01 89.1% 76.3%
2pfdA03 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.76 64.0 4.91e-01 91.3% 62.6%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.75 63.0 5.03e-01 92.4% 59.2%
4o6yB00 1.20.120.1770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.74 63.0 4.84e-01 93.5% 58.3%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.74 55.0 5.95e-01 90.2% 94.8%
8hk0C01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.74 52.0 4.41e-01 73.9% 56.0%
4rm7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.74 53.0 4.55e-01 73.9% 58.3%
1y1uA01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.73 61.0 4.75e-01 91.3% 90.3%
4g80T00 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.72 63.0 5.45e-01 95.7% 66.2%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.71 58.0 5.67e-01 91.3% 88.2%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.70 57.0 5.37e-01 87.0% 89.0%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.70 57.0 5.38e-01 88.0% 89.9%
1io1A01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.70 59.0 4.82e-01 92.4% 59.2%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 63.0 5.24e-01 98.9% 63.6%
7xxiA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.68 54.0 3.76e-01 83.7% 78.6%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 56.0 5.15e-01 90.2% 90.8%
8g52B01 1.25.40.920 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TRAP transporter T-component 0.68 62.0 4.38e-01 100.0% 45.6%
2wauA02 1.20.58.830 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 54.0 4.94e-01 90.2% 95.1%
2oocB00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.65 48.0 4.65e-01 78.3% 94.3%
5mlc900 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.65 53.0 5.05e-01 88.0% 90.7%
2xvtC00 1.10.150.510 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Receptor activity modifying family 0.65 48.0 5.17e-01 91.3% 92.4%
3jrtA00 1.20.120.1060 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.64 55.0 4.55e-01 93.5% 72.9%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.64 55.0 4.77e-01 93.5% 77.3%
7tj9A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.63 55.0 5.28e-01 96.7% 84.0%
2a2fX01 1.10.357.30 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Exocyst complex subunit Sec15 C-terminal domain, N-terminal subdomain 0.60 54.0 4.46e-01 100.0% 90.4%
4exjA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 51.0 4.75e-01 97.8% 81.8%
2h7oA01 1.20.120.1330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Rac1-binding domain, N-terminal GTPase binding subdomain 0.60 52.0 4.76e-01 97.8% 85.4%
1wtyA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.59 50.0 4.64e-01 92.4% 82.8%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 47.0 4.05e-01 92.4% 69.1%
4me9B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 50.0 4.04e-01 97.8% 49.5%
2jexA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.55 46.0 4.60e-01 91.3% 100.0%
2d2mD00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.53 41.0 3.55e-01 83.7% 55.9%
1sz9C00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.52 46.0 4.03e-01 98.9% 79.3%
ECOD (63)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3934654 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.84 71.0 5.58e-01 90.2% 60.0%
3737781 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.82 70.0 6.71e-01 91.3% 87.6%
3479092 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.81 70.0 6.77e-01 91.3% 89.0%
3641718 604.5.1.52 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › DUF7610 0.80 65.0 6.97e-01 87.0% 100.0%
3453715 603.1.1.118 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF7610 0.80 68.0 6.88e-01 91.3% 95.6%
3373206 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.79 67.0 4.54e-01 90.2% 56.8%
3581262 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.79 65.0 6.65e-01 88.0% 94.4%
3786136 603.1.1.3 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.79 67.0 6.22e-01 91.3% 79.1%
3533309 603.1.1.3 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.78 67.0 6.41e-01 91.3% 87.6%
5027868 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.78 64.0 4.50e-01 88.0% 41.5%
4942916 601.12.1.1 alpha bundles › Four-helical up-and-down bundle › Nickel-containing superoxide dismutase, NiSOD › Nickel-containing superoxide dismutase, NiSOD › Sod_Ni 0.77 63.0 5.24e-01 87.0% 65.8%
3388607 603.1.1.105 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF31021 0.77 64.0 6.24e-01 88.0% 96.0%
3474661 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.77 64.0 5.98e-01 90.2% 82.6%
4032384 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.77 61.0 6.43e-01 91.3% 96.2%
3923984 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.77 63.0 6.31e-01 89.1% 95.8%
3510469 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.77 64.0 6.08e-01 91.3% 84.5%
3807 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.76 63.0 5.25e-01 89.1% 62.2%
3662533 603.1.1.138 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › BPS1 0.76 63.0 6.41e-01 88.0% 98.9%
4944639 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.76 60.0 6.01e-01 84.8% 92.6%
3221759 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.76 62.0 4.86e-01 88.0% 46.8%
3669053 109.4.1.98 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.76 64.0 4.43e-01 91.3% 29.2%
3175456 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.75 68.0 4.01e-01 98.9% 27.7%
3237761 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.75 62.0 6.11e-01 90.2% 92.0%
3743047 604.5.1.28 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › TBCC_N 0.75 62.0 6.45e-01 89.1% 96.5%
3740232 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.75 69.0 5.92e-01 100.0% 91.4%
3526861 603.1.1.99 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.75 64.0 6.05e-01 92.4% 83.6%
3726914 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.75 63.0 5.37e-01 91.3% 58.6%
5041469 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.74 67.0 4.95e-01 100.0% 56.2%
3203655 601.16.1.0 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase 0.74 63.0 5.46e-01 92.4% 64.3%
5043155 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.74 62.0 5.62e-01 91.3% 76.8%
3540972 174.1.1.34 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › FAM70 0.74 61.0 5.22e-01 90.2% 69.3%
5061228 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.74 62.0 6.04e-01 91.3% 87.0%
3490690 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.74 53.0 4.78e-01 75.0% 64.8%
3416148 633.6.1.12 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX+ACOX_C_alpha1 0.73 53.0 3.48e-01 75.0% 26.6%
3271959 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.73 62.0 6.20e-01 91.3% 88.4%
3927845 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.73 63.0 5.61e-01 94.6% 78.5%
3526587 109.4.1.839 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Maestro_HEAT 0.73 64.0 4.30e-01 96.7% 46.9%
4972684 150.3.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine 0.73 62.0 5.80e-01 90.2% 77.3%
3256816 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 57.0 4.82e-01 100.0% 52.0%
3228669 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.72 61.0 4.99e-01 92.4% 65.5%
5074738 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.71 59.0 5.16e-01 91.3% 60.7%
4009028 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.71 50.0 4.56e-01 72.8% 77.5%
3675605 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.71 63.0 4.61e-01 98.9% 72.6%
3220791 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.71 57.0 4.57e-01 89.1% 81.6%
3214189 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.70 58.0 5.60e-01 91.3% 97.1%
3709676 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.70 63.0 4.47e-01 100.0% 76.4%
3296716 109.4.1.1264 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_16 0.70 58.0 4.19e-01 91.3% 33.6%
3466658 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 57.0 3.95e-01 91.3% 27.0%
3959716 633.6.1.0 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.69 49.0 4.69e-01 75.0% 75.5%
3328924 5069.1.1.7 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.69 61.0 4.82e-01 95.7% 54.4%
4977418 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.68 54.0 5.08e-01 89.1% 70.9%
3560836 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.68 61.0 4.78e-01 100.0% 47.2%
3756667 109.25.1.0 alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A 0.68 60.0 4.92e-01 100.0% 53.5%
3627345 109.27.1.0 alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain 0.67 60.0 4.96e-01 100.0% 69.1%
3459951 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.67 56.0 5.31e-01 92.4% 94.5%
4236667 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.67 47.0 3.43e-01 73.9% 45.1%
3731155 109.4.1.85 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nop52 0.66 58.0 4.33e-01 100.0% 82.1%
4024565 603.6.1.0 alpha bundles › STAT-like › MukF C-terminal domain-like › MukF C-terminal domain-like 0.65 59.0 4.23e-01 98.9% 36.1%
3487385 109.21.1.1 alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleopor_Nup85 0.65 59.0 3.73e-01 100.0% 56.3%
5007869 601.33.1.0 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.61 50.0 4.94e-01 91.3% 85.0%
3263848 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.61 51.0 4.96e-01 91.3% 91.0%
3248050 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.58 49.0 4.13e-01 94.6% 55.6%
5013803 3843.1.1.4 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB 0.55 46.0 4.20e-01 91.3% 68.8%
D2 medium residues 556-569_591-642
PDB
Domain cluster: representative
CATH (19)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.68 37.0 3.55e-01 90.9% 45.9%
2l3lA01 1.20.58.1250 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain 0.66 39.0 3.31e-01 95.5% 35.8%
2efvA00 3.30.70.3260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Uncharacterised protein PF10802, DUF2540 0.62 52.0 4.88e-01 93.9% 81.7%
3n98A01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.62 43.0 2.62e-01 72.7% 15.1%
4i8oA03 1.10.8.1130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Bacterial toxin RNase RnlA/LsoA, C-terminal Dmd-binding domain 0.60 41.0 4.11e-01 78.8% 70.1%
3nrhA00 1.20.120.1550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Protein of unknown function DUF5063 0.58 49.0 3.81e-01 98.5% 60.1%
2iw3A02 1.20.1390.20 Mainly Alpha › Up-down Bundle › PWI domain › 0.56 48.0 4.39e-01 100.0% 90.0%
3e3vA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 34.0 3.76e-01 78.8% 77.4%
3dteA01 1.10.10.2910 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.54 42.0 3.55e-01 86.4% 94.0%
3djbA01 1.10.472.50 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like 0.53 37.0 3.32e-01 72.7% 95.8%
3vayA02 1.20.120.1600 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.53 46.0 4.24e-01 100.0% 95.4%
5t3wA00 1.20.120.1160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.53 46.0 3.68e-01 98.5% 75.9%
4mk6A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 46.0 3.38e-01 100.0% 49.5%
2xvtC00 1.10.150.510 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Receptor activity modifying family 0.53 36.0 3.42e-01 100.0% 59.5%
5dvwA00 1.20.120.1160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.52 45.0 3.65e-01 98.5% 78.8%
6lcuA02 1.10.10.470 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Maltooligosyl trehalose synthase; domain 4 0.52 44.0 3.89e-01 100.0% 94.3%
4bbrM00 1.10.472.170 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › 0.52 44.0 3.17e-01 95.5% 52.3%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.51 37.0 3.38e-01 78.8% 58.8%
2yy5A02 1.10.240.10 Mainly Alpha › Orthogonal Bundle › Tyrosyl-Transfer RNA Synthetase › Tyrosyl-Transfer RNA Synthetase 0.51 44.0 3.70e-01 100.0% 93.3%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1554358 3146.1.1.1 a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.97 93.0 5.24e-01 100.0% 14.7%
3271988 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.71 43.0 4.19e-01 98.5% 54.8%
3436123 101.1.17.0 alpha arrays › HTH › HTH › FF domain 0.71 58.0 5.56e-01 92.4% 78.7%
4012210 601.14.1.0 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin 0.63 35.0 2.71e-01 95.5% 23.3%
4258320 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.60 41.0 3.95e-01 77.3% 60.0%
3392375 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.60 34.0 3.41e-01 90.9% 54.3%
4344761 195.1.1.1 alpha complex topology › NusB-like › NusB-like › NusB-like › NusB 0.59 42.0 3.38e-01 75.8% 40.7%
3281755 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.59 38.0 4.00e-01 75.8% 71.7%
4031187 632.19.1.3 alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › DUF1542 0.58 38.0 3.66e-01 95.5% 58.7%
4014515 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.56 40.0 3.65e-01 78.8% 57.9%
3644409 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.55 45.0 3.94e-01 90.9% 62.0%
4027497 1128.1.1.0 alpha bundles › LYR protein › LYR protein › LYR protein 0.54 41.0 4.25e-01 98.5% 90.0%
4939616 633.12.1.0 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like 0.52 40.0 3.74e-01 98.5% 65.9%
4670553 150.1.1.106 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › PigN 0.52 36.0 2.91e-01 75.8% 99.3%
4080847 4953.1.1.0 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.51 38.0 3.82e-01 83.3% 90.0%
D3 medium residues 643-673_696-716
PDB
Domain cluster: representative
D4 medium residues 674-695_717-808
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17488.8 best Herpes_glycoH_C 29.4 8.10e-07 74.6% 47.5%
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xqyA03 2.60.40.3190 Mainly Beta › Sandwich › Immunoglobulin-like › Herpesvirus glycoprotein H, C-terminal domain 0.88 79.0 7.44e-01 93.9% 90.2%
3m1cA04 2.60.40.3190 Mainly Beta › Sandwich › Immunoglobulin-like › Herpesvirus glycoprotein H, C-terminal domain 0.84 80.0 7.53e-01 99.1% 95.5%
7b7nH01 2.60.40.3190 Mainly Beta › Sandwich › Immunoglobulin-like › Herpesvirus glycoprotein H, C-terminal domain 0.79 70.0 6.76e-01 93.0% 95.3%
2r6fA03 3.30.1490.20 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain 0.65 38.0 4.59e-01 71.9% 90.3%
4m8aA00 3.30.720.210 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › 0.63 28.0 3.51e-01 72.8% 68.7%
3nwnA00 3.40.850.10 Alpha Beta › 3-Layer(aba) Sandwich › Kinesin › Kinesin motor domain 0.59 44.0 3.27e-01 78.9% 51.3%
2h6oA01 2.60.40.2800 Mainly Beta › Sandwich › Immunoglobulin-like › 0.59 43.0 3.97e-01 76.3% 93.3%
4iajA00 3.30.1490.390 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Protein of unknown function DUF4649 0.59 34.0 3.93e-01 96.5% 81.6%
4es8B02 2.60.40.3580 Mainly Beta › Sandwich › Immunoglobulin-like › 0.59 43.0 4.56e-01 74.6% 93.1%
4gqzA00 2.60.40.3700 Mainly Beta › Sandwich › Immunoglobulin-like › 0.59 41.0 3.67e-01 73.7% 51.9%
2pn5A02 2.60.40.1930 Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain 0.57 40.0 4.26e-01 73.7% 95.0%
2j1vA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.56 41.0 3.82e-01 75.4% 87.2%
2a74A02 2.60.40.1930 Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain 0.56 40.0 4.24e-01 74.6% 98.0%
5hccB02 2.60.40.1930 Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain 0.56 41.0 4.42e-01 75.4% 100.0%
1v8hA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 40.0 4.17e-01 76.3% 100.0%
1dd1A00 2.60.200.10 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.54 43.0 3.48e-01 85.1% 82.8%
1a21A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 40.0 4.24e-01 76.3% 96.9%
5icuA00 2.60.40.1220 Mainly Beta › Sandwich › Immunoglobulin-like › 0.54 39.0 4.17e-01 75.4% 93.1%
5c71A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 38.0 4.11e-01 71.9% 93.8%
4h87A00 2.60.200.20 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.54 37.0 3.63e-01 70.2% 88.7%
2pttB00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 40.0 4.13e-01 78.1% 98.1%
2b5iC01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 39.0 4.25e-01 76.3% 99.0%
1lwrA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 40.0 4.29e-01 77.2% 94.8%
3tcaA01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.54 35.0 3.90e-01 71.1% 84.4%
2ed8A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 38.0 4.31e-01 73.7% 100.0%
3r8qA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 38.0 4.26e-01 75.4% 97.8%
1y6kR01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 39.0 4.11e-01 77.2% 92.2%
7zxkB02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 38.0 4.12e-01 74.6% 100.0%
3l5iA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 38.0 4.22e-01 74.6% 100.0%
3rriA00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.52 33.0 3.22e-01 98.2% 55.0%
3dlqR02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 38.0 4.04e-01 76.3% 92.0%
3noiA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 41.0 4.05e-01 86.8% 96.6%
1x5aA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 37.0 4.03e-01 75.4% 95.6%
3oq3B01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 40.0 3.87e-01 82.5% 79.4%
3qt2A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 37.0 3.97e-01 76.3% 92.8%
ECOD (31)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1309233 3145.1.1.1 beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C 0.88 79.0 7.12e-01 93.9% 81.1%
119479 3145.1.1.1 beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C 0.84 80.0 7.20e-01 99.1% 85.7%
1936537 3145.1.1.1 beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C 0.78 71.0 6.39e-01 95.6% 85.2%
2095502 3145.1.1.1 beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C 0.78 71.0 6.46e-01 96.5% 87.6%
4830885 3145.1.1.1 beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C 0.73 57.0 5.97e-01 95.6% 89.4%
5081326 11.1.1.608 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Por_Secre_tail 0.71 39.0 4.98e-01 71.1% 93.8%
4942476 11.1.4.23 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like › CarboxypepD_reg 0.70 39.0 4.63e-01 70.2% 78.8%
4983601 11.1.4.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like 0.68 39.0 4.30e-01 70.2% 70.0%
3608427 11.2.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.62 40.0 4.07e-01 71.9% 66.1%
3174815 11.1.4.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like 0.61 42.0 4.36e-01 72.8% 76.2%
3927867 11.1.4.70 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like › NOMO1-like_1st 0.60 38.0 4.18e-01 72.8% 78.9%
4975837 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.60 39.0 4.38e-01 70.2% 84.4%
3309894 11.1.4.72 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like › NOMO1-like_2nd 0.59 39.0 4.25e-01 72.8% 80.0%
4014979 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.59 42.0 4.28e-01 73.7% 100.0%
3588234 11.1.4.36 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like › SpaA 0.58 39.0 4.16e-01 71.9% 78.0%
3188391 11.1.1.926 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF7136 0.58 41.0 3.48e-01 73.7% 69.3%
4002070 11.1.1.102 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › A2M_BRD 0.58 43.0 3.05e-01 78.9% 26.9%
3476163 11.1.1.31 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › MG2 0.57 41.0 4.36e-01 74.6% 95.0%
5041899 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.57 39.0 3.89e-01 70.2% 91.7%
3714847 11.1.1.45 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Sec63 0.57 41.0 4.13e-01 74.6% 94.8%
5056414 11.18.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › N-terminal domain in metallo-endopeptidase BACOVA_00663 › N-terminal domain in metallo-endopeptidase BACOVA_00663 0.56 40.0 3.87e-01 74.6% 83.8%
5028273 11.18.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › N-terminal domain in metallo-endopeptidase BACOVA_00663 › N-terminal domain in metallo-endopeptidase BACOVA_00663 0.55 39.0 4.11e-01 71.9% 90.0%
5041319 10.4.1.0 beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain 0.54 36.0 4.04e-01 76.3% 85.6%
3421892 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.53 38.0 4.05e-01 84.2% 85.0%
3769454 11.1.1.178 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_2 0.53 38.0 4.15e-01 74.6% 94.7%
4929726 10.1.2.0 beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.53 39.0 4.13e-01 85.1% 84.8%
3830724 207.1.1.95 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_14 0.53 43.0 2.61e-01 91.2% 23.9%
3802666 207.1.1.133 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_1, LRR_14 0.52 42.0 2.88e-01 90.4% 43.1%
5068794 11.1.1.15 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PKD 0.52 38.0 4.15e-01 75.4% 96.8%
3461175 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 36.0 3.90e-01 74.6% 84.2%
4959253 11.1.4.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like 0.52 36.0 3.73e-01 71.1% 80.0%