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envelope_glycoprotein_H

Euk-Vir

Panine_betaherpesvirus_2

envelope_glycoprotein_H__NP_612708__Panine_betaherpesvirus_2__188763

Identity

Accession:
NP_612708 ↗
Protein ID:
envelope_glycoprotein_H
Kingdom:
euk

Quality

75.8 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Cytomegalovirus› Panine_betaherpesvirus_2

TaxID: 188763

Cluster

View cluster (43 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 209-318
PDB
Domain cluster: rep: orf22__YP_009044405__Alcelaphine_gammaherpesvirus_2__138184__D149-254
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 49.0 5.50e-13 98.2% 22.9%
D2 medium residues 589-657
PDB
Domain cluster: rep: envelope_glycoprotein_H__YP_009179315__Elephant_endotheliotropic_herpesvirus_4__548914__D571-650
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17488.8 best Herpes_glycoH_C 43.5 3.70e-11 94.2% 43.3%
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3m1cA04 2.60.40.3190 Mainly Beta › Sandwich › Immunoglobulin-like › Herpesvirus glycoprotein H, C-terminal domain 0.78 54.0 4.25e-01 81.2% 37.1%
1k8kD01 3.30.1460.20 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.70 54.0 4.17e-01 82.6% 71.5%
2xqyA03 2.60.40.3190 Mainly Beta › Sandwich › Immunoglobulin-like › Herpesvirus glycoprotein H, C-terminal domain 0.70 52.0 4.21e-01 98.6% 41.4%
4bfeA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.70 51.0 4.83e-01 76.8% 82.7%
3eaaA00 2.30.110.20 Mainly Beta › Roll › Pnp Oxidase; Chain A › Hcp1-like 0.68 50.0 3.80e-01 78.3% 77.8%
7k0xA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.67 48.0 4.65e-01 75.4% 87.2%
4frwA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.66 48.0 4.35e-01 78.3% 78.1%
4lfhD02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.65 48.0 4.47e-01 78.3% 81.2%
4w64B00 2.30.110.20 Mainly Beta › Roll › Pnp Oxidase; Chain A › Hcp1-like 0.64 44.0 3.39e-01 72.5% 95.6%
3fbqA01 2.60.40.1630 Mainly Beta › Sandwich › Immunoglobulin-like › bacillus anthracis domain 0.63 48.0 3.86e-01 84.1% 64.6%
2b5iB01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 46.0 4.16e-01 78.3% 78.7%
3ifrB02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.62 46.0 3.17e-01 79.7% 54.5%
1bdfA01 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.62 44.0 3.93e-01 78.3% 83.0%
6ue9L02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 44.0 3.73e-01 78.3% 73.8%
4nzdB01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.60 45.0 4.00e-01 79.7% 81.8%
2itmB02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.60 45.0 3.12e-01 79.7% 55.1%
1k3eB02 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.60 45.0 3.98e-01 81.2% 81.0%
3a5vA02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.59 41.0 3.72e-01 73.9% 91.9%
1iarB01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 43.0 3.92e-01 79.7% 79.2%
4mypA00 2.60.40.1850 Mainly Beta › Sandwich › Immunoglobulin-like › 0.58 50.0 4.22e-01 97.1% 92.6%
3rbsA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 42.0 3.99e-01 79.7% 77.3%
2di7A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 43.0 3.83e-01 82.6% 83.2%
7y8sA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 43.0 3.87e-01 79.7% 84.2%
1x1iA03 2.60.220.10 Mainly Beta › Sandwich › Chondroitinase Ac; Chain A, domain 3 › Polysaccharide lyase family 8-like, C-terminal 0.57 44.0 3.73e-01 85.5% 77.1%
7uwjC02 2.60.40.2150 Mainly Beta › Sandwich › Immunoglobulin-like › Interleukin-17 receptor A/B, fibronectin-III-like domain 2 0.56 41.0 3.79e-01 81.2% 75.3%
2bhoA00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.56 46.0 4.08e-01 97.1% 92.7%
1qzzA03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 43.0 3.28e-01 84.1% 52.7%
1o7dC02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.56 42.0 3.93e-01 84.1% 98.9%
1nnjA01 3.20.190.10 Alpha Beta › Alpha-Beta Barrel › N-terminal domain of MutM-like DNA repair proteins › MutM-like, N-terminal 0.54 43.0 3.50e-01 87.0% 59.1%
2q7nA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 40.0 3.81e-01 79.7% 77.8%
4wqmA02 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.54 40.0 3.68e-01 84.1% 85.7%
4i8oA02 3.30.160.690 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Bacterial toxin RNase RnlA/LsoA, N repeated domain 0.53 44.0 4.03e-01 91.3% 77.8%
2vzyC00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.53 43.0 3.18e-01 89.9% 85.2%
2bzvA00 2.60.90.10 Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › Adenovirus pIV-related, attachment domain 0.53 41.0 3.25e-01 85.5% 89.0%
2xg5B01 2.60.40.1090 Mainly Beta › Sandwich › Immunoglobulin-like › Fimbrial-type adhesion domain 0.52 38.0 3.21e-01 81.2% 89.7%
2covG00 2.60.40.2450 Mainly Beta › Sandwich › Immunoglobulin-like › Beta-1,3-xylanase, CBM31 domain 0.52 39.0 3.69e-01 82.6% 73.9%
1ghpA00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.52 43.0 2.98e-01 95.7% 90.7%
1xdzA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 42.0 2.95e-01 91.3% 45.8%
2v8qA01 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.51 44.0 4.04e-01 97.1% 80.9%
ECOD (23)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2095502 3145.1.1.1 ↗ beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C 0.94 85.0 6.41e-01 95.7% 44.8%
4604481 12.3.1.8 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_65N 0.73 55.0 3.76e-01 81.2% 84.6%
1309233 3145.1.1.1 ↗ beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C 0.70 55.0 4.25e-01 100.0% 39.2%
3595869 319.1.1.0 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.69 48.0 4.29e-01 72.5% 92.6%
3265120 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.67 50.0 3.76e-01 79.7% 78.9%
119479 3145.1.1.1 ↗ beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C 0.65 56.0 4.34e-01 95.7% 44.2%
4015971 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.64 51.0 4.78e-01 87.0% 98.8%
3251338 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.64 51.0 4.67e-01 87.0% 86.7%
3357534 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.58 43.0 3.83e-01 81.2% 76.2%
3891879 11.1.1.117 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › EpoR_lig-bind 0.58 43.0 3.82e-01 82.6% 76.2%
4241488 237.1.1.5 ↗ a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › RolB_RolC 0.57 46.0 3.61e-01 91.3% 94.8%
4117538 237.1.1.5 ↗ a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › RolB_RolC 0.56 40.0 3.31e-01 76.8% 84.4%
4071792 3504.2.1.1 ↗ beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco 0.55 42.0 3.41e-01 81.2% 57.8%
4056544 11.1.1.233 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_mannosidase 0.55 41.0 4.10e-01 79.7% 91.9%
4291331 3504.2.1.1 ↗ beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco 0.55 41.0 3.33e-01 81.2% 57.0%
None — 0.54 42.0 2.94e-01 84.1% 39.6%
4228206 708.1.1.0 ↗ beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.54 44.0 4.18e-01 97.1% 77.5%
4169255 2003.1.5.25 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GidB 0.53 41.0 2.90e-01 85.5% 38.1%
4188674 4263.2.1.1 ↗ a+b two layers › TTHA1528-like › FtsH Periplasmic Domain › FtsH Periplasmic Domain › FtsH_ext 0.53 38.0 3.54e-01 76.8% 66.7%
3575256 11.1.1.673 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › CUT_N 0.53 39.0 3.73e-01 78.3% 97.5%
3684421 10.12.1.0 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.52 39.0 3.05e-01 84.1% 40.6%
4926813 11.1.4.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like 0.51 37.0 3.53e-01 79.7% 81.2%
3956105 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.50 37.0 3.49e-01 79.7% 81.2%
D3 medium residues 658-736
PDB
Domain cluster: rep: envelope_glycoprotein_H__YP_004936041__Cercopithecine_betaherpesvirus_5__50292__D611-687
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17488.8 best Herpes_glycoH_C 72.5 4.10e-20 96.2% 53.2%