←Back to structures

envelope_glycoprotein_H

Euk-Vir

Human_herpesvirus_5

envelope_glycoprotein_H__YP_002608267__Human_herpesvirus_5__10359

Identity

Accession:: YP_002608267 ↗
Protein ID:: envelope_glycoprotein_H
Kingdom:: euk

Quality

72.0 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Cytomegalovirus› Human_betaherpesvirus_5

TaxID: 10359

Cluster

View cluster (43 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 42-102

PDB

D2 medium residues 162-192_333-345_359-461

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02489.22 best	Herpes_glycop_H	64.1	1.40e-17	81.0%	21.2%

CATH (14)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3dssB00	1.50.10.20	Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase ›	0.68	51.0	3.86e-01	76.9%	54.4%
7fhyB01	1.50.10.100	Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase	0.68	51.0	4.08e-01	78.9%	78.7%
3lewA01	1.25.40.390	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.58	47.0	3.70e-01	87.1%	63.7%
1ki1B01	1.20.900.10	Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain	0.57	39.0	3.57e-01	70.1%	94.0%
2dbaA01	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.56	33.0	3.68e-01	78.9%	72.9%
3efzB00	1.20.190.20	Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain	0.54	45.0	3.93e-01	89.1%	83.6%
4q5nA02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.54	40.0	4.50e-01	86.4%	100.0%
3kezA01	1.25.40.390	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.54	45.0	3.83e-01	88.4%	87.7%
1zeeA01	1.20.58.600	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.54	40.0	4.44e-01	78.9%	99.2%
3ic8A02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.53	35.0	4.08e-01	76.9%	96.0%
5w0kA01	3.90.380.20	Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Herpesvirus glycoprotein H, domain D-II	0.53	43.0	3.35e-01	85.7%	71.1%
7ae2A01	1.20.120.580	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like	0.53	32.0	3.31e-01	78.9%	62.8%
4jgwA01	1.20.870.10	Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1	0.53	38.0	3.76e-01	73.5%	70.5%
2hujA00	1.20.120.440	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like	0.50	35.0	3.80e-01	80.3%	84.0%

ECOD (8)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2095503	3146.1.1.1 ↗	a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H	0.95	92.0	5.99e-01	100.0%	57.5%
3708425	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.58	40.0	3.86e-01	70.1%	100.0%
3734018	109.4.1.356 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans	0.56	48.0	3.30e-01	92.5%	54.5%
4030209	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.54	38.0	3.48e-01	79.6%	55.3%
3273962	627.1.1.1 ↗	alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9	0.52	37.0	3.39e-01	72.8%	81.5%
3472840	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.51	45.0	3.01e-01	95.2%	45.6%
3595734	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.51	34.0	3.54e-01	78.9%	71.4%
3409854	129.1.1.16 ↗	alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › NAD_binding_11	0.51	35.0	3.76e-01	71.4%	81.5%

D3 medium residues 193-294

PDB

Domain cluster: rep: orf22__YP_009044405__Alcelaphine_gammaherpesvirus_2__138184__D149-254

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02489.22 best	Herpes_glycop_H	85.2	5.80e-24	100.0%	23.8%

D4 medium residues 295-332_346-358

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02489.22 best	Herpes_glycop_H	22.0	8.10e-05	90.2%	8.4%

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2ew2A02	1.10.1040.10	Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2	0.63	48.0	3.62e-01	86.3%	46.3%
2kvuA00	1.10.720.30	Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › SAP domain	0.55	37.0	3.34e-01	70.6%	61.3%

ECOD (1)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3995159	197.1.1.1 ↗	alpha bundles › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › FERM_M	0.55	45.0	3.54e-01	92.2%	53.0%

D5 medium residues 462-602

PDB

Domain cluster: rep: Cy104__YP_009337514__Cynomolgus_cytomegalovirus__1919083__D475-586

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02489.22 best	Herpes_glycop_H	98.6	4.90e-28	71.6%	22.0%

D6 medium residues 603-674

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF17488.8 best	Herpes_glycoH_C	79.4	3.00e-22	100.0%	51.1%

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
7b7nH01	2.60.40.3190	Mainly Beta › Sandwich › Immunoglobulin-like › Herpesvirus glycoprotein H, C-terminal domain	0.76	66.0	5.44e-01	100.0%	54.3%

ECOD (3)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2095502	3145.1.1.1 ↗	beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C	0.89	81.0	6.25e-01	100.0%	48.3%
1936537	3145.1.1.1 ↗	beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C	0.75	67.0	5.29e-01	100.0%	49.0%
4830885	3145.1.1.1 ↗	beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C	0.73	61.0	5.45e-01	94.4%	66.3%