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envelope_glycoprotein_H

Euk-Vir

Saimiriine_betaherpesvirus_4

envelope_glycoprotein_H__YP_004940238__Saimiriine_betaherpesvirus_4__1535247

Identity

Accession:
YP_004940238 ↗
Protein ID:
envelope_glycoprotein_H
Kingdom:
euk

Quality

79.8 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 13-88
PDB
D2 medium residues 89-135_149-256
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 33.8 2.10e-08 64.5% 17.0%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5w0kA01 3.90.380.20 Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Herpesvirus glycoprotein H, domain D-II 0.88 84.0 6.38e-01 100.0% 69.8%
3eb8B01 3.10.450.460 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › EspG protein, N-terminal domain 0.61 25.0 4.03e-01 91.0% 100.0%
4ggtB00 2.40.128.30 Mainly Beta › Beta Barrel › Lipocalin › Avidin-like 0.56 33.0 3.93e-01 85.8% 84.9%
3p24A01 2.40.128.470 Mainly Beta › Beta Barrel › Lipocalin › 0.52 36.0 3.71e-01 71.0% 91.5%
4on1A01 2.40.128.470 Mainly Beta › Beta Barrel › Lipocalin › 0.51 35.0 3.71e-01 70.3% 89.9%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2095503 3146.1.1.1 a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.88 85.0 5.66e-01 100.0% 38.7%
2095478 3146.1.1.1 a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.87 83.0 5.59e-01 100.0% 44.4%
2701125 3146.1.1.1 a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.82 78.0 5.29e-01 100.0% 44.3%
3793430 274.1.1.0 a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.56 34.0 4.24e-01 84.5% 97.9%
5043414 4252.1.1.0 beta barrels › AttH-like › AttH-like › AttH-like 0.52 35.0 3.75e-01 80.6% 78.5%
3479716 3459.1.1.0 beta sandwiches › Fas apoptotic inhibitory molecule › Fas apoptotic inhibitory molecule › Fas apoptotic inhibitory molecule 0.52 28.0 3.79e-01 85.8% 98.8%
3953302 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.52 33.0 3.90e-01 81.9% 94.2%
D3 medium residues 257-337
PDB
Domain cluster: representative
CATH (64)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.83 68.0 6.14e-01 86.4% 81.9%
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.80 56.0 6.21e-01 87.7% 93.7%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.79 64.0 5.81e-01 86.4% 82.4%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.78 59.0 6.18e-01 88.9% 87.8%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.78 59.0 6.07e-01 88.9% 86.7%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 60.0 5.62e-01 84.0% 77.2%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 60.0 5.60e-01 85.2% 87.3%
2xl4A00 1.20.120.1420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain 0.76 62.0 5.02e-01 87.7% 60.5%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 63.0 5.82e-01 88.9% 88.1%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.76 57.0 5.81e-01 85.2% 82.3%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.75 62.0 5.43e-01 88.9% 61.2%
1quuA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 61.0 5.19e-01 86.4% 71.4%
2xqyA01 3.30.500.50 Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › 0.75 68.0 5.21e-01 100.0% 46.6%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.75 62.0 5.07e-01 88.9% 54.5%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.74 61.0 4.82e-01 88.9% 67.7%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 67.0 5.38e-01 100.0% 79.9%
3u8vA00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.73 51.0 5.10e-01 88.9% 71.1%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.73 59.0 5.32e-01 88.9% 65.5%
3edvA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 58.0 4.46e-01 86.4% 49.2%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.73 58.0 5.58e-01 86.4% 79.6%
3r6nA02 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 59.0 4.76e-01 88.9% 88.4%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.72 60.0 4.86e-01 88.9% 49.7%
3pe0A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 58.0 5.31e-01 87.7% 83.0%
3cqcB01 1.20.58.1380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 58.0 5.64e-01 93.8% 78.9%
3eabE00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.71 57.0 5.63e-01 86.4% 89.5%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.71 55.0 5.45e-01 85.2% 79.3%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.70 54.0 5.63e-01 88.9% 90.7%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.70 55.0 5.43e-01 88.9% 81.2%
2b1eA04 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.70 61.0 5.31e-01 98.8% 81.1%
2y1vA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.70 58.0 4.39e-01 88.9% 40.0%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.70 53.0 4.99e-01 84.0% 68.0%
1kt1A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 56.0 4.48e-01 92.6% 44.9%
2vzbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.69 56.0 4.48e-01 88.9% 80.8%
2fbnA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 55.0 4.46e-01 95.1% 45.8%
4nq0A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 63.0 4.37e-01 100.0% 68.1%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.69 56.0 4.98e-01 88.9% 69.2%
3fnbA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.69 60.0 5.37e-01 97.5% 77.2%
5j1hA01 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 57.0 4.40e-01 91.4% 76.4%
3kr9A02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.68 45.0 4.97e-01 74.1% 90.2%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.68 53.0 4.97e-01 88.9% 67.6%
6yz2A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.68 54.0 4.79e-01 87.7% 69.2%
7smtA02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.68 54.0 4.19e-01 86.4% 41.4%
5o5jT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.67 48.0 4.78e-01 88.9% 72.9%
8hdlA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.66 51.0 3.65e-01 88.9% 27.8%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.66 49.0 5.05e-01 90.1% 85.7%
6fndA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.66 56.0 4.32e-01 95.1% 43.5%
2a9uA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.65 54.0 4.71e-01 92.6% 60.3%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.65 52.0 4.81e-01 90.1% 66.7%
8gy0A01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.65 57.0 3.89e-01 96.3% 47.3%
2wl8C00 1.20.120.900 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pex19, mPTS binding domain 0.65 46.0 4.18e-01 81.5% 55.0%
1blwC00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.65 51.0 4.25e-01 85.2% 70.9%
3cwzB01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.63 49.0 4.13e-01 86.4% 82.9%
3apzA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.63 55.0 3.79e-01 100.0% 54.5%
1tqgA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.62 46.0 4.28e-01 88.9% 61.9%
3ucaA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.61 53.0 3.67e-01 97.5% 39.1%
2yxhA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.59 47.0 4.20e-01 84.0% 60.2%
3u3iA02 1.20.58.1110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 51.0 4.71e-01 98.8% 75.9%
2uubT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.58 47.0 4.45e-01 91.4% 76.8%
4qndA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.57 42.0 4.05e-01 80.2% 82.5%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.55 46.0 4.59e-01 98.8% 91.6%
3nkzA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.55 46.0 4.35e-01 88.9% 79.4%
2gsvA00 6.10.140.40 Special › Helix non-globular › Helix Hairpins › 0.54 41.0 4.39e-01 84.0% 97.0%
4zvaA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.53 45.0 3.80e-01 100.0% 61.7%
1ux8A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.50 43.0 3.86e-01 98.8% 75.4%
ECOD (65)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3364492 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.85 68.0 5.45e-01 85.2% 56.0%
3624435 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.85 68.0 5.39e-01 85.2% 65.2%
3592177 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.82 62.0 6.62e-01 85.2% 92.9%
3583102 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.82 65.0 6.63e-01 86.4% 86.3%
3479953 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.81 65.0 6.39e-01 85.2% 81.2%
3389546 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.81 66.0 6.68e-01 88.9% 87.5%
4997415 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.81 67.0 5.52e-01 88.9% 52.1%
3504889 604.22.1.1 alpha bundles › Spectrin repeat-like › tubulin binding cofactor C N-terminal domain › tubulin binding cofactor C N-terminal domain › TBCC_N 0.81 67.0 6.62e-01 88.9% 85.9%
3884665 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.80 66.0 5.40e-01 87.7% 53.6%
3358888 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.80 59.0 5.35e-01 85.2% 58.2%
3892492 604.1.1.66 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_1st_PEPL 0.80 65.0 5.85e-01 87.7% 79.1%
3939383 603.1.1.19 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-18_N 0.79 63.0 4.61e-01 85.2% 49.0%
3557114 604.1.1.66 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_1st_PEPL 0.79 65.0 5.84e-01 87.7% 79.1%
3648998 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.79 59.0 5.77e-01 85.2% 72.2%
None 0.78 63.0 4.58e-01 95.1% 33.3%
3253634 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.77 62.0 5.70e-01 88.9% 66.7%
3973500 601.1.2.144 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › HBM 0.77 62.0 5.50e-01 86.4% 62.6%
3580346 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.77 62.0 4.38e-01 86.4% 43.4%
3375600 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.77 61.0 5.89e-01 85.2% 81.1%
5004483 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.76 61.0 6.01e-01 86.4% 81.2%
3576628 109.21.1.2 alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nup96 0.76 65.0 3.83e-01 91.4% 13.8%
3501998 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.76 58.0 5.78e-01 86.4% 78.8%
3815122 604.12.1.68 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF6857 0.76 63.0 4.76e-01 88.9% 41.7%
3461370 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.75 61.0 6.05e-01 88.9% 88.2%
4226243 109.4.1.1320 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7, TPR_10, TPR_12 0.75 60.0 4.01e-01 86.4% 23.3%
3254229 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.74 58.0 6.06e-01 88.9% 90.7%
3471396 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.74 62.0 5.90e-01 88.9% 83.2%
3807085 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.74 60.0 5.99e-01 88.9% 84.7%
4662540 633.31.1.0 alpha bundles › Bromodomain-like › Four-helical bundle insertion domain in pyruvate-ferredoxin oxidoreductase › Four-helical bundle insertion domain in pyruvate-ferredoxin oxidoreductase 0.73 53.0 5.49e-01 86.4% 81.3%
3835373 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.72 59.0 4.80e-01 88.9% 48.7%
3910597 603.1.1.8 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Spectrin_2 0.72 57.0 5.00e-01 87.7% 59.2%
3719058 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.72 53.0 5.30e-01 87.7% 76.5%
3236284 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.71 59.0 5.94e-01 88.9% 93.8%
5052922 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.71 56.0 4.96e-01 86.4% 58.3%
5019950 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 62.0 4.07e-01 100.0% 23.1%
3788590 109.4.1.464 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exportin-T 0.70 62.0 4.34e-01 98.8% 45.8%
None 0.70 56.0 3.75e-01 86.4% 23.0%
3703032 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.70 57.0 4.98e-01 90.1% 88.8%
3812310 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.70 56.0 4.49e-01 86.4% 45.8%
4524825 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.70 58.0 5.48e-01 88.9% 75.8%
3392425 109.4.1.235 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP68 0.70 55.0 3.90e-01 86.4% 32.8%
3449851 604.12.1.94 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › USP8_dimer 0.70 55.0 5.01e-01 88.9% 63.6%
4383079 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.69 57.0 4.57e-01 88.9% 46.5%
3500905 604.13.1.1 alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like › USP8_dimer 0.69 61.0 5.29e-01 98.8% 65.6%
4977048 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.69 55.0 5.10e-01 88.9% 68.0%
1867183 603.1.1.8 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Spectrin_2 0.69 56.0 5.53e-01 88.9% 85.9%
162201 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.68 57.0 5.07e-01 91.4% 74.1%
3788338 604.12.1.9 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT2 0.68 52.0 5.40e-01 88.9% 89.2%
3828167 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.68 53.0 4.31e-01 86.4% 45.6%
3924661 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.67 60.0 5.02e-01 100.0% 90.0%
5014600 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 58.0 5.09e-01 98.8% 66.4%
3359510 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.65 51.0 4.20e-01 86.4% 45.2%
3629701 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.65 53.0 5.23e-01 92.6% 85.9%
3803172 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.65 51.0 4.14e-01 86.4% 43.8%
3414322 109.4.1.87 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec6 0.65 56.0 3.35e-01 100.0% 26.4%
3370936 6155.1.1.0 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter 0.64 54.0 5.31e-01 97.5% 100.0%
3277087 192.4.1.0 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) 0.63 52.0 5.03e-01 98.8% 78.9%
3316910 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.63 50.0 4.15e-01 88.9% 46.5%
3843378 109.4.1.1811 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_TT21_2nd, ARM_TT21_N 0.61 54.0 3.59e-01 100.0% 29.2%
4025746 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.60 48.0 3.86e-01 88.9% 61.2%
3197548 3755.2.1.0 alpha bundles › YscO-like › Flagellar FliJ protein › Flagellar FliJ protein 0.58 45.0 3.78e-01 86.4% 88.0%
3632143 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.58 45.0 3.74e-01 86.4% 85.2%
4179875 3930.1.1.0 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.56 43.0 3.64e-01 86.4% 48.3%
3852 622.2.1.1 alpha bundles › YvfG-like › YvfG-like › YvfG-like › YvfG 0.54 41.0 4.39e-01 84.0% 97.0%
56761 150.3.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine 0.52 40.0 3.43e-01 86.4% 78.4%
D4 medium residues 338-401
PDB
Domain cluster: representative
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3mfnB00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.66 46.0 3.71e-01 73.4% 53.2%
2pn5A09 1.50.10.20 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.62 54.0 3.53e-01 100.0% 61.9%
8h6rA01 1.20.930.10 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.61 46.0 4.29e-01 84.4% 80.0%
3n2oA03 1.20.58.930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 45.0 3.96e-01 79.7% 76.0%
1sr2A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.59 45.0 3.75e-01 84.4% 53.4%
2ys8A00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.58 43.0 3.90e-01 81.2% 81.1%
2chpA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 43.0 3.44e-01 84.4% 92.6%
3ff5A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 41.0 4.40e-01 76.6% 100.0%
1ze0A01 1.20.120.700 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nitrate reductase, subunit delta (NarJ) 0.57 41.0 3.82e-01 87.5% 58.3%
3fhdA01 1.20.120.860 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Herpesvirus alkaline exonuclease, N-terminal domain 0.55 38.0 3.01e-01 71.9% 91.9%
1wmgA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.51 36.0 3.24e-01 75.0% 75.6%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3817305 109.4.1.420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.70 54.0 3.76e-01 82.8% 28.8%
3438832 109.4.1.1308 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3, TPR_24 0.68 51.0 3.12e-01 81.2% 14.2%
5028925 109.4.1.207 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_2 0.65 50.0 4.24e-01 84.4% 52.3%
3371755 109.4.1.1286 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_12 0.63 48.0 3.72e-01 82.8% 43.3%
4048456 604.34.1.1 alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase › Arg_decarb_HB 0.63 42.0 3.85e-01 70.3% 65.6%
3307371 109.4.1.420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.63 47.0 3.46e-01 82.8% 29.7%
3368689 7579.1.1.59 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › LIDHydrolase 0.51 43.0 2.88e-01 100.0% 84.7%
3239361 226.1.1.1 a+b two layers › POZ domain › POZ domain › POZ domain › BTB 0.51 39.0 3.35e-01 87.5% 61.7%
D5 medium residues 402-519
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 56.0 4.10e-15 98.3% 24.6%
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xqyA02 1.20.58.1340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 65.0 6.06e-01 100.0% 80.4%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 43.0 4.04e-01 76.3% 80.5%
4lqkA00 1.10.437.20 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus 0.59 37.0 3.64e-01 83.1% 56.8%
4dlqA02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.58 38.0 4.12e-01 100.0% 82.1%
4a64C03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.57 40.0 4.34e-01 100.0% 86.0%
2fbnA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 46.0 4.28e-01 90.7% 69.3%
8d0vA01 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.56 49.0 3.50e-01 100.0% 31.5%
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.55 39.0 4.26e-01 90.7% 89.7%
1kt1A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 45.0 4.12e-01 90.7% 66.5%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.55 37.0 3.61e-01 91.5% 61.5%
2nxpB00 1.25.40.500 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TFIID subunit TAF5, NTD2 domain 0.54 38.0 3.58e-01 77.1% 59.3%
7um4A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.53 43.0 3.42e-01 89.0% 82.5%
1dk8A02 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.52 33.0 3.83e-01 88.1% 88.2%
3pjaJ01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.52 40.0 3.87e-01 80.5% 78.6%
7tj9A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.52 38.0 4.05e-01 89.0% 85.8%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.50 39.0 3.87e-01 83.9% 92.1%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2095503 3146.1.1.1 a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.92 84.0 5.28e-01 100.0% 21.6%
2701125 3146.1.1.1 a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.84 79.0 5.03e-01 99.2% 24.3%
4225834 109.4.1.19 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vitellogenin_N 0.60 52.0 3.87e-01 99.2% 35.7%
3896467 5000.4.1.5 alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain › PF27742 0.59 46.0 3.71e-01 83.9% 52.8%
4385935 5000.4.1.1 alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain › Endotoxin_N 0.57 46.0 3.66e-01 88.1% 59.6%
3619810 109.25.1.1 alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN 0.56 45.0 4.57e-01 86.4% 96.5%
3937072 109.4.1.370 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Symplekin_C 0.54 46.0 4.13e-01 94.9% 67.1%
4530962 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 45.0 4.37e-01 92.4% 88.7%
3805407 109.4.1.420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.52 40.0 3.51e-01 98.3% 52.4%
3919069 176.1.1.2 alpha arrays › Annexin › Annexin › Annexin › Annexin_2 0.51 40.0 4.26e-01 83.9% 96.2%
3312606 176.1.1.1 alpha arrays › Annexin › Annexin › Annexin › Annexin 0.51 34.0 3.96e-01 91.5% 100.0%
3878144 601.1.2.2 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › I_LWEQ 0.51 35.0 3.43e-01 91.5% 62.2%
D6 medium residues 520-666
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17488.8 best Herpes_glycoH_C 110.4 8.30e-32 95.9% 99.3%