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envelope_glycoprotein_H

Euk-Vir

Equid_alphaherpesvirus_3

envelope_glycoprotein_H__YP_009054943__Equid_alphaherpesvirus_3__80341

Identity

Accession:
YP_009054943 ↗
Protein ID:
envelope_glycoprotein_H
Kingdom:
euk

Quality

71.5 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Varicellovirus› Equid_alphaherpesvirus_3

TaxID: 80341

Cluster

View cluster (30 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 142-183
PDB
D2 medium residues 224-351
PDB
Domain cluster: rep: envelope_glycoprotein_H__YP_010087581__Cervid_alphaherpesvirus_3__2115790__D207-328
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xqyA01 3.30.500.50 Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › 0.77 50.0 4.42e-01 80.5% 47.2%
1p6pA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.76 35.0 3.61e-01 74.2% 45.6%
3rbyA02 2.40.128.310 Mainly Beta › Beta Barrel › Lipocalin › Protein HRI1, C-terminal domain 0.65 36.0 4.16e-01 92.2% 73.7%
2it9A00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.65 31.0 3.24e-01 94.5% 48.3%
6fopA01 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.64 51.0 4.22e-01 84.4% 71.7%
8bddA02 2.70.98.70 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.64 55.0 3.94e-01 92.2% 89.4%
1mmuA00 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.63 45.0 3.31e-01 72.7% 90.6%
5upiA01 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.62 49.0 4.30e-01 84.4% 88.3%
1a2vA03 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.60 47.0 3.27e-01 83.6% 92.7%
3w7tA01 2.70.98.50 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › putative glycoside hydrolase family protein from bacillus halodurans 0.60 42.0 3.49e-01 72.7% 78.9%
3w9kA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.58 37.0 3.63e-01 72.7% 60.0%
2ffsA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.55 37.0 3.62e-01 75.0% 61.4%
5gv0A00 2.40.160.110 Mainly Beta › Beta Barrel › Porin › 0.54 39.0 3.58e-01 73.4% 66.0%
6cz4A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.53 28.0 3.31e-01 81.2% 73.3%
3wa5B00 2.60.120.1690 Mainly Beta › Sandwich › Jelly Rolls › 0.52 38.0 3.90e-01 75.0% 91.9%
1cgtA02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.52 30.0 3.49e-01 87.5% 77.7%
1lfoA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.52 30.0 3.06e-01 73.4% 55.9%
1ealA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.52 34.0 3.47e-01 70.3% 67.7%
ECOD (20)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1554358 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.90 87.0 5.39e-01 100.0% 21.8%
2095476 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.88 85.0 5.31e-01 100.0% 22.7%
119302 3146.1.1.0 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain 0.77 51.0 3.71e-01 82.8% 26.2%
2998372 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.71 31.0 4.73e-01 71.9% 100.0%
3474457 319.1.1.0 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.69 32.0 3.70e-01 73.4% 58.9%
3584281 12.3.1.13 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_38C 0.66 52.0 4.02e-01 84.4% 86.2%
1503842 9.27.1.1 ↗ beta barrels › Lipocalins/Streptavidin › LpqH › LpqH › Myco_19_kDa 0.65 36.0 3.79e-01 74.2% 59.6%
3223040 12.3.1.13 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_38C 0.64 50.0 4.06e-01 83.6% 94.5%
3556710 9.1.1.24 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin_7 0.64 31.0 3.18e-01 74.2% 44.5%
2095503 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.64 58.0 3.85e-01 99.2% 37.4%
2389389 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.63 49.0 4.12e-01 82.0% 74.4%
4113893 12.3.1.34 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › SOGP_N 0.61 48.0 3.77e-01 82.8% 89.1%
4989818 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.61 49.0 4.15e-01 87.5% 90.9%
3171148 12.3.1.9 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_81 0.60 48.0 3.61e-01 85.9% 63.3%
3588455 274.1.1.0 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.60 26.0 3.49e-01 71.1% 74.3%
5014493 331.3.1.12 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like › STK_08120-like 0.60 34.0 2.82e-01 71.9% 31.3%
3188851 9.14.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Uncharacterized protein YLR301W › Uncharacterized protein YLR301W › HRI1 0.58 38.0 4.12e-01 90.6% 77.3%
3962450 9.27.1.0 ↗ beta barrels › Lipocalins/Streptavidin › LpqH › LpqH 0.56 37.0 4.07e-01 81.2% 81.9%
5014686 809.2.1.0 ↗ a+b two layers › BLIP-like › BT0923-like › BT0923-like 0.55 25.0 3.36e-01 85.2% 90.9%
3191832 12.3.1.36 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › DUF5127 0.54 43.0 3.39e-01 84.4% 91.3%
D3 medium residues 352-453
PDB
Domain cluster: rep: envelope_glycoprotein_H__YP_068353__Suid_alphaherpesvirus_1__10345__D240-339
D4 medium residues 454-546
PDB
Domain cluster: rep: envelope_glycoprotein_H__NP_045257__Equid_alphaherpesvirus_4__10331__D432-555
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.75 54.0 5.23e-01 75.3% 90.2%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 65.0 5.51e-01 98.9% 80.5%
1chuA03 1.20.58.100 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain 0.70 49.0 5.08e-01 73.1% 83.0%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 53.0 4.44e-01 83.9% 84.6%
3wd6A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.66 52.0 4.85e-01 86.0% 90.7%
4qndA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.65 47.0 4.65e-01 75.3% 81.4%
4c9bB00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.64 54.0 3.91e-01 94.6% 49.5%
2rkkA01 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.64 49.0 4.19e-01 83.9% 91.0%
2kmfA01 1.20.58.810 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 0.64 46.0 4.52e-01 76.3% 75.5%
2g3bA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.63 47.0 3.82e-01 80.6% 92.0%
1tjoB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 45.0 3.72e-01 76.3% 79.4%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.62 44.0 4.01e-01 74.2% 71.2%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.61 43.0 3.86e-01 74.2% 72.6%
4a15A03 1.10.275.40 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › 0.60 46.0 4.06e-01 81.7% 71.4%
4im7A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.60 44.0 3.47e-01 78.5% 70.2%
2qgmA03 1.20.1440.30 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Biosynthetic Protein domain 0.60 44.0 4.16e-01 78.5% 62.9%
2vyiA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 44.0 3.99e-01 98.9% 56.2%
2pihA00 1.20.1500.10 Mainly Alpha › Up-down Bundle › YheA-like fold › YheA/YmcA-like 0.60 37.0 3.36e-01 87.1% 46.3%
2mpkA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 43.0 4.73e-01 76.3% 100.0%
3u3iA02 1.20.58.1110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 48.0 4.61e-01 89.2% 92.6%
2ff4A02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 46.0 3.74e-01 92.5% 42.9%
6fdpA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 43.0 4.01e-01 98.9% 60.0%
4gouA03 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.59 47.0 3.74e-01 87.1% 71.6%
2rekA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 46.0 3.81e-01 83.9% 55.8%
8amzP01 1.25.40.570 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.59 48.0 3.31e-01 95.7% 23.2%
3dcfA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 42.0 3.71e-01 76.3% 56.3%
3vprA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 42.0 3.69e-01 76.3% 65.5%
1f5mA00 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.57 43.0 3.58e-01 82.8% 99.4%
4b94A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 43.0 3.85e-01 100.0% 55.3%
4jgwA01 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.56 47.0 4.01e-01 93.5% 61.5%
2hr2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 47.0 3.98e-01 96.8% 55.8%
3qwwA03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 44.0 3.61e-01 91.4% 44.0%
2x6hA01 1.25.40.70 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Phosphatidylinositol 3-kinase, accessory domain (PIK) 0.55 43.0 3.49e-01 93.5% 43.0%
2raeA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 39.0 3.41e-01 74.2% 78.8%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.54 38.0 3.68e-01 74.2% 95.4%
2v5cA03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.51 43.0 3.91e-01 93.5% 83.8%
2ijqA00 1.10.3450.10 Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › TTHA0068-like 0.51 40.0 3.51e-01 86.0% 57.9%
3i2fA02 1.10.3020.10 Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain) 0.51 29.0 2.96e-01 75.3% 53.7%
1m5iA00 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.50 33.0 3.24e-01 87.1% 60.0%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4963427 604.2.1.0 ↗ alpha bundles › Spectrin repeat-like › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 0.72 50.0 5.02e-01 72.0% 75.8%
3887920 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.70 50.0 4.26e-01 75.3% 73.5%
3198009 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.70 50.0 5.21e-01 75.3% 89.4%
5039404 604.2.1.0 ↗ alpha bundles › Spectrin repeat-like › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 0.70 49.0 5.34e-01 75.3% 90.7%
3519581 604.12.1.4 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT1 0.69 51.0 4.46e-01 76.3% 79.3%
3486748 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.69 50.0 4.80e-01 75.3% 94.3%
3686188 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 62.0 4.38e-01 100.0% 67.1%
4982987 3352.1.1.1 ↗ alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3 0.68 56.0 3.72e-01 91.4% 39.0%
3789370 109.4.1.1289 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30856 0.67 54.0 3.74e-01 89.2% 73.7%
3904584 109.4.1.62 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nic96 0.67 52.0 3.85e-01 83.9% 35.8%
4344287 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 60.0 4.70e-01 100.0% 73.8%
3630440 109.4.1.1328 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26034 0.66 59.0 5.53e-01 100.0% 86.1%
3468130 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 50.0 3.76e-01 97.8% 32.1%
3684480 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 54.0 5.06e-01 90.3% 86.1%
3704321 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.61 44.0 4.54e-01 75.3% 91.8%
4515121 109.4.1.1253 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_Atp25_C 0.60 52.0 3.58e-01 97.8% 27.4%
3657582 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 51.0 4.35e-01 96.8% 59.5%
3602414 2004.1.1.411 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T1RH-like_C 0.60 53.0 4.91e-01 100.0% 95.8%
5015029 5059.1.1.1 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.59 46.0 3.27e-01 82.8% 73.2%
4998009 3352.1.1.0 ↗ alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain 0.58 50.0 3.44e-01 98.9% 53.1%
3345919 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 49.0 4.73e-01 96.8% 84.5%
5022103 5059.1.1.1 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.58 45.0 3.19e-01 83.9% 73.8%
3640422 5059.1.1.1 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.57 44.0 3.02e-01 81.7% 72.0%
5054700 5059.1.1.1 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.56 44.0 3.10e-01 82.8% 73.4%
3174456 5059.1.1.1 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.56 43.0 3.00e-01 82.8% 70.0%
4973925 7516.1.1.2 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.55 39.0 2.77e-01 76.3% 51.6%
3597100 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 44.0 3.82e-01 91.4% 55.8%
5028782 5073.1.2.0 ↗ alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain 0.52 44.0 3.47e-01 94.6% 84.9%