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envelope_glycoprotein_H
Euk-VirHuman_alphaherpesvirus_1
envelope_glycoprotein_H__YP_009137096__Human_alphaherpesvirus_1__10298
Identity
- Accession:
- YP_009137096 ↗
- Protein ID:
- envelope_glycoprotein_H
- Kingdom:
- euk
Quality
74.1
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Simplexvirus›
Human_alphaherpesvirus_1
TaxID: 10298
Cluster
View cluster (30 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 466-634
Domain cluster:
rep: envelope_glycoprotein_H__YP_053085__Equid_alphaherpesvirus_1__10326__D464-476_499-660
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02489.22 best | Herpes_glycop_H | 31.8 | 8.70e-08 | 97.6% | 24.8% |
D2
high
residues 650-795
Domain cluster:
rep: UL22__YP_003084400__Anatid_alphaherpesvirus_1__104388__D647-783
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF17488.8 best | Herpes_glycoH_C | 48.2 | 1.30e-12 | 97.3% | 91.5% |
D3
medium
residues 82-121_136-179
D4
medium
residues 232-326
Domain cluster:
rep: envelope_glycoprotein_H__YP_010087581__Cervid_alphaherpesvirus_3__2115790__D207-328
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2xqyA01 | 3.30.500.50 | Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › | 0.83 | 57.0 | 4.52e-01 | 88.4% | 37.6% |
| 1lfoA00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.70 | 41.0 | 3.76e-01 | 100.0% | 44.1% |
| 4azpA00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.69 | 41.0 | 3.61e-01 | 98.9% | 41.8% |
| 3imhA00 | 2.70.98.10 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.68 | 61.0 | 4.22e-01 | 100.0% | 94.6% |
| 1nkgA01 | 2.70.98.10 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.66 | 58.0 | 4.29e-01 | 98.9% | 79.7% |
| 3rbyA02 | 2.40.128.310 | Mainly Beta › Beta Barrel › Lipocalin › Protein HRI1, C-terminal domain | 0.65 | 42.0 | 4.28e-01 | 100.0% | 66.3% |
| 1mmuA00 | 2.70.98.10 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.65 | 57.0 | 3.91e-01 | 97.9% | 90.0% |
| 1av4A03 | 2.70.98.20 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain | 0.64 | 55.0 | 3.61e-01 | 96.8% | 84.7% |
| 4k35A02 | 2.70.98.30 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 | 0.63 | 55.0 | 4.36e-01 | 97.9% | 77.5% |
| 3w7tA01 | 2.70.98.50 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › putative glycoside hydrolase family protein from bacillus halodurans | 0.62 | 55.0 | 4.18e-01 | 98.9% | 79.3% |
| 6fopA01 | 2.70.98.30 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 | 0.62 | 54.0 | 4.16e-01 | 100.0% | 69.9% |
| 5upiA01 | 2.70.98.30 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 | 0.59 | 52.0 | 4.23e-01 | 100.0% | 86.2% |
| 4exrA01 | 3.10.450.40 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.59 | 35.0 | 3.82e-01 | 88.4% | 70.4% |
| 4exrA02 | 3.10.450.40 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.56 | 32.0 | 3.71e-01 | 89.5% | 76.1% |
| 5e1qA03 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.56 | 39.0 | 3.98e-01 | 73.7% | 99.0% |
| 3tzgA00 | 2.40.160.150 | Mainly Beta › Beta Barrel › Porin › | 0.55 | 39.0 | 2.96e-01 | 100.0% | 29.7% |
| 5gv0A00 | 2.40.160.110 | Mainly Beta › Beta Barrel › Porin › | 0.54 | 49.0 | 4.07e-01 | 98.9% | 65.4% |
| 4akmB00 | 2.40.160.110 | Mainly Beta › Beta Barrel › Porin › | 0.54 | 49.0 | 4.12e-01 | 98.9% | 66.2% |
| 4ktpB02 | 2.60.420.10 | Mainly Beta › Sandwich › Maltose phosphorylase, domain 3 › Maltose phosphorylase, domain 3 | 0.53 | 38.0 | 4.01e-01 | 97.9% | 85.4% |
| 2bseA00 | 2.60.40.1830 | Mainly Beta › Sandwich › Immunoglobulin-like › Phage tail base-plate Siphoviridae RBP, head domain | 0.53 | 37.0 | 3.56e-01 | 71.6% | 94.4% |
| 2v7sA00 | 3.30.2030.20 | Alpha Beta › 2-Layer Sandwich › TBP-like › | 0.53 | 43.0 | 3.50e-01 | 85.3% | 72.8% |
| 4fr9A00 | 3.10.450.360 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.52 | 41.0 | 3.61e-01 | 94.7% | 57.4% |
| 1sgoA01 | 3.30.2280.10 | Alpha Beta › 2-Layer Sandwich › copper amine oxidase-like fold › Hypothetical protein (hspc210) | 0.52 | 36.0 | 3.50e-01 | 72.6% | 88.0% |
| 3u1wA01 | 3.10.450.360 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.51 | 40.0 | 3.28e-01 | 94.7% | 43.7% |
| 3pg1A01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.51 | 38.0 | 3.41e-01 | 76.8% | 83.7% |
| 2ffsA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.51 | 39.0 | 3.41e-01 | 97.9% | 53.8% |
| 4hbrA00 | 3.10.450.360 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.51 | 40.0 | 3.57e-01 | 94.7% | 57.9% |
| 3bgtA01 | 2.40.400.10 | Mainly Beta › Beta Barrel › Acetoacetate decarboxylase-like › Acetoacetate decarboxylase-like | 0.50 | 43.0 | 3.27e-01 | 94.7% | 83.1% |
ECOD (26)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1554358 | 3146.1.1.1 ↗ | a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H | 0.89 | 84.0 | 5.00e-01 | 100.0% | 15.9% |
| 2095476 | 3146.1.1.1 ↗ | a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H | 0.86 | 81.0 | 4.87e-01 | 100.0% | 16.8% |
| 119302 | 3146.1.1.0 ↗ | a+b complex topology › gH main domain › gH main domain › gH main domain | 0.82 | 59.0 | 3.94e-01 | 91.6% | 21.4% |
| 4956163 | 71.1.1.0 ↗ | beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB | 0.79 | 45.0 | 3.58e-01 | 100.0% | 30.6% |
| 2998372 | 12.1.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain | 0.74 | 41.0 | 5.34e-01 | 96.8% | 98.1% |
| 2095503 | 3146.1.1.1 ↗ | a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H | 0.73 | 64.0 | 3.97e-01 | 100.0% | 17.2% |
| 3474457 | 319.1.1.0 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones | 0.73 | 42.0 | 4.26e-01 | 98.9% | 57.9% |
| 3375268 | 5084.5.1.3 ↗ | beta barrels › Outer membrane meander beta-barrels › Porins › Porin › Porin_3 | 0.69 | 46.0 | 3.43e-01 | 81.1% | 29.5% |
| 3990496 | 12.1.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain | 0.69 | 42.0 | 4.79e-01 | 100.0% | 82.9% |
| 3968451 | 12.3.1.3 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Aldose_epim | 0.68 | 61.0 | 4.36e-01 | 98.9% | 84.1% |
| 4128674 | 4252.1.1.3 ↗ | beta barrels › AttH-like › AttH-like › AttH-like › DA_C | 0.68 | 50.0 | 3.74e-01 | 100.0% | 33.5% |
| 3584281 | 12.3.1.13 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_38C | 0.67 | 58.0 | 4.19e-01 | 97.9% | 74.1% |
| 3223040 | 12.3.1.13 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_38C | 0.67 | 58.0 | 4.32e-01 | 97.9% | 91.0% |
| 3252995 | 12.3.1.46 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › ComC_SSD | 0.66 | 58.0 | 4.38e-01 | 95.8% | 92.0% |
| 3222216 | 12.1.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain | 0.66 | 39.0 | 4.43e-01 | 100.0% | 78.6% |
| 5014685 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.66 | 38.0 | 4.54e-01 | 89.5% | 84.6% |
| 2389389 | 12.3.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich | 0.64 | 56.0 | 4.34e-01 | 98.9% | 67.6% |
| 3588455 | 274.1.1.0 ↗ | a+b two layers › Pili subunits › Pili subunits › Pili subunits | 0.63 | 35.0 | 4.03e-01 | 96.8% | 74.3% |
| 2717534 | 12.3.1.31 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › YgjK_N | 0.62 | 54.0 | 3.91e-01 | 97.9% | 64.3% |
| 3188851 | 9.14.1.1 ↗ | beta barrels › Lipocalins/Streptavidin › Uncharacterized protein YLR301W › Uncharacterized protein YLR301W › HRI1 | 0.60 | 46.0 | 4.36e-01 | 82.1% | 69.1% |
| 3427945 | 284.1.3.0 ↗ | a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain | 0.59 | 38.0 | 3.78e-01 | 100.0% | 62.0% |
| 3886275 | 331.3.1.4 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › IP_trans | 0.58 | 53.0 | 3.98e-01 | 100.0% | 62.2% |
| 5013018 | 274.1.1.0 ↗ | a+b two layers › Pili subunits › Pili subunits › Pili subunits | 0.54 | 45.0 | 4.06e-01 | 94.7% | 65.4% |
| 4014982 | 7579.1.1.0 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases | 0.53 | 41.0 | 2.86e-01 | 82.1% | 55.6% |
| 4021361 | 12.1.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain | 0.52 | 35.0 | 3.66e-01 | 70.5% | 95.5% |
| 3739528 | 5.1.3.19 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Hira | 0.50 | 37.0 | 2.99e-01 | 80.0% | 83.4% |
D5
medium
residues 327-434
Domain cluster:
rep: envelope_glycoprotein_H__YP_068353__Suid_alphaherpesvirus_1__10345__D240-339