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envelope_glycoprotein_H

Euk-Vir

Leporid_alphaherpesvirus_4

envelope_glycoprotein_H__YP_009230153__Leporid_alphaherpesvirus_4__481315

Identity

Accession:
YP_009230153 ↗
Protein ID:
envelope_glycoprotein_H
Kingdom:
euk

Quality

76.9 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Simplexvirus› Leporid_alphaherpesvirus_4

TaxID: 481315

Cluster

View cluster (30 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 50-133_156-173
PDB
D2 medium residues 174-355
PDB
Domain cluster: rep: envelope_glycoprotein_H__YP_009042084__Fruit_bat_alphaherpesvirus_1__1343901__D163-212_227-348_450-466
D3 medium residues 356-455
PDB
Domain cluster: rep: envelope_glycoprotein_H__YP_068353__Suid_alphaherpesvirus_1__10345__D240-339
D4 medium residues 456-564
PDB
Domain cluster: representative
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 60.0 5.43e-01 95.4% 85.7%
4dloB02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.68 57.0 5.61e-01 90.8% 92.3%
3zheA02 1.25.40.760 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.67 59.0 4.82e-01 99.1% 81.6%
4it4A02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.67 46.0 4.97e-01 92.7% 85.7%
3mpxA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.66 55.0 4.49e-01 90.8% 71.4%
5l0wB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.66 52.0 4.82e-01 100.0% 66.7%
7fhyB01 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.66 60.0 4.37e-01 100.0% 39.9%
2rpaA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.66 43.0 4.98e-01 89.0% 94.8%
2i2oA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.65 59.0 4.75e-01 100.0% 58.8%
4i1aA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.65 54.0 4.02e-01 98.2% 35.8%
4y6cA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 55.0 4.44e-01 96.3% 49.5%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.63 43.0 4.78e-01 93.6% 90.6%
6fndA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 54.0 4.61e-01 98.2% 100.0%
5jpoD02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 54.0 5.10e-01 98.2% 93.2%
1zu2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 52.0 4.67e-01 99.1% 66.5%
3bbyA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 48.0 4.71e-01 85.3% 88.9%
2qk2A01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.60 53.0 4.19e-01 100.0% 58.5%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.59 54.0 4.40e-01 100.0% 87.0%
3ly7A02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 42.0 3.76e-01 99.1% 50.9%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 48.0 4.07e-01 90.8% 52.7%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.58 53.0 4.63e-01 99.1% 92.1%
2a2fX02 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.58 48.0 4.62e-01 93.6% 90.7%
5a4uF02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 45.0 4.35e-01 83.5% 76.9%
3bhqA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 47.0 3.93e-01 90.8% 76.7%
2pziB03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 41.0 3.71e-01 91.7% 54.7%
2lxlA00 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.55 49.0 4.29e-01 99.1% 91.4%
5zw7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 44.0 3.93e-01 85.3% 98.7%
2f2bA00 1.20.1080.10 Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. 0.55 46.0 3.66e-01 95.4% 85.7%
4a64C03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.54 45.0 4.64e-01 90.8% 100.0%
2w0gA00 1.20.58.610 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Cdc37, Hsp90 binding domain 0.52 42.0 4.01e-01 88.1% 86.8%
1yowA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.52 42.0 3.37e-01 89.9% 84.3%
1fx8A00 1.20.1080.10 Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. 0.52 44.0 3.50e-01 99.1% 86.6%
3ucaA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.52 42.0 3.22e-01 89.9% 51.8%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2095476 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.92 87.0 5.31e-01 100.0% 18.9%
3697513 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.78 70.0 5.18e-01 97.2% 48.7%
4018727 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.77 71.0 5.69e-01 100.0% 69.8%
3722840 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.77 71.0 4.57e-01 100.0% 83.9%
3187297 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.76 70.0 4.57e-01 100.0% 91.4%
3736151 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.75 68.0 4.36e-01 100.0% 29.7%
3919515 109.4.1.1492 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_SCC3-SA, PF31007 0.74 68.0 4.43e-01 100.0% 28.0%
3729008 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.73 66.0 4.24e-01 100.0% 32.9%
3824114 604.6.1.24 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF6857 0.72 65.0 6.19e-01 100.0% 100.0%
3639843 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 66.0 4.31e-01 100.0% 28.2%
3191000 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.71 63.0 4.33e-01 100.0% 49.9%
3629060 109.4.1.1463 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28490 0.69 62.0 3.65e-01 99.1% 15.7%
3867624 109.4.1.3415 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28426 0.69 62.0 4.69e-01 100.0% 54.0%
3925416 109.4.1.1361 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_CAND1 0.69 62.0 4.89e-01 100.0% 68.4%
3805391 109.4.1.1185 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BTB-POZ_ANK-like 0.69 61.0 4.69e-01 100.0% 69.0%
3736050 109.4.1.510 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HbrB 0.68 60.0 4.80e-01 100.0% 87.8%
3365642 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 61.0 4.81e-01 100.0% 78.2%
3740779 604.12.1.2 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 0.66 44.0 5.12e-01 100.0% 98.7%
3696544 109.4.1.1508 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Not1, ARM_Cnot1 0.65 58.0 3.78e-01 100.0% 39.4%
3632024 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 55.0 5.16e-01 100.0% 76.3%
3677502 604.10.1.5 ↗ alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac › Nic96 0.64 57.0 5.24e-01 100.0% 81.4%
3734308 109.4.1.58 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Not1 0.64 57.0 3.73e-01 100.0% 40.0%
3634790 109.4.1.138 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PAT1 0.63 57.0 3.84e-01 100.0% 38.5%
3549920 601.1.2.5 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › TLN1-like_RS 0.62 43.0 3.80e-01 70.6% 59.4%
3401149 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 54.0 4.50e-01 100.0% 71.2%
3239225 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 51.0 4.53e-01 99.1% 61.2%
3507936 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 52.0 4.52e-01 100.0% 58.9%
3499614 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 53.0 3.83e-01 99.1% 35.7%
3788741 109.4.1.58 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Not1 0.61 51.0 3.92e-01 96.3% 55.0%
3688832 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 54.0 4.49e-01 99.1% 70.5%
3282788 109.4.1.194 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_10 0.58 50.0 4.40e-01 97.2% 63.6%
3616025 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 50.0 3.98e-01 100.0% 46.1%
3277674 109.3.1.377 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › PF26994 0.57 47.0 4.39e-01 93.6% 83.4%
3936862 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 46.0 3.98e-01 96.3% 89.4%
3601214 5048.1.1.0 ↗ alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like 0.51 39.0 3.09e-01 80.7% 90.6%
D5 medium residues 565-648
PDB
Domain cluster: rep: glycoprotein_H__YP_009227255__Macropodid_alphaherpesvirus_1__137443__D601-683
D6 medium residues 649-809
PDB
Domain cluster: rep: UL22__YP_003084400__Anatid_alphaherpesvirus_1__104388__D647-783
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17488.8 best Herpes_glycoH_C 34.4 2.40e-08 88.8% 93.6%