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envelope_glycoprotein_H

Euk-Vir

Columbid_alphaherpesvirus_1

envelope_glycoprotein_H__YP_009352929__Columbid_alphaherpesvirus_1__93386

Identity

Accession:
YP_009352929 ↗
Protein ID:
envelope_glycoprotein_H
Kingdom:
euk

Quality

72.1 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Mardivirus› Columbid_alphaherpesvirus_1

TaxID: 93386

Cluster

View cluster (30 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 73-117_119-125
PDB
D2 medium residues 137-148_160-207_294-431
PDB
Domain cluster: representative
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 35.0 4.73e-01 74.7% 93.3%
4od4A02 1.20.120.1780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase 0.66 33.0 4.28e-01 73.2% 80.7%
2d4uB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.66 36.0 4.05e-01 76.8% 67.7%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.66 34.0 4.20e-01 75.8% 78.5%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.63 33.0 4.42e-01 75.8% 95.1%
1j1jA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.63 38.0 4.63e-01 81.3% 90.2%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.63 34.0 3.51e-01 73.2% 56.0%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.61 34.0 4.05e-01 75.8% 78.5%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 33.0 3.82e-01 79.3% 69.8%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.60 28.0 4.19e-01 89.9% 98.9%
3tixA02 6.10.140.1690 Special › Helix non-globular › Helix Hairpins › 0.60 26.0 3.96e-01 73.7% 100.0%
1quuA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 33.0 4.03e-01 75.8% 83.3%
2dnxA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 34.0 4.12e-01 75.8% 85.4%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.59 32.0 4.22e-01 74.7% 95.5%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 35.0 3.76e-01 74.2% 76.9%
4m0mA03 1.20.1270.430 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.52 22.0 3.41e-01 72.7% 100.0%
1io1A01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.51 29.0 3.19e-01 70.7% 65.7%
2hroA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.50 27.0 3.32e-01 89.9% 80.5%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2095476 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.84 80.0 5.55e-01 99.5% 52.6%
1554358 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.82 78.0 5.40e-01 99.5% 54.1%
4971843 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.73 33.0 4.80e-01 75.3% 94.4%
4996069 604.10.1.0 ↗ alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac 0.73 34.0 4.93e-01 75.8% 96.7%
3266118 603.1.1.100 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 0.67 35.0 4.36e-01 75.3% 80.0%
3892492 604.1.1.66 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_1st_PEPL 0.67 34.0 4.53e-01 74.2% 89.1%
3775375 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.64 34.0 3.84e-01 75.3% 66.0%
3586824 601.1.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.63 31.0 2.40e-01 77.3% 21.7%
3243897 3684.1.1.0 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.61 35.0 4.11e-01 77.3% 78.6%
3583302 633.23.1.4 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › Claudin_2 0.59 35.0 4.13e-01 75.8% 82.9%
162404 603.1.1.6 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.59 34.0 4.12e-01 75.8% 85.4%
4020089 6155.1.1.2 ↗ alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.58 35.0 4.04e-01 77.3% 82.1%
3473090 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.57 35.0 4.16e-01 76.8% 86.4%
5041952 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.57 38.0 4.57e-01 86.9% 99.3%
4839189 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.56 35.0 4.24e-01 81.8% 97.5%
3600827 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.56 32.0 4.10e-01 70.7% 96.5%
3318923 603.1.1.124 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE, V-SNARE_C 0.55 40.0 4.52e-01 88.4% 96.8%
3713307 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.53 40.0 4.56e-01 87.9% 99.4%
3341058 6155.1.1.6 ↗ alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › DUF2921 0.53 33.0 3.88e-01 80.8% 88.9%
3225420 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 30.0 3.31e-01 74.7% 66.3%
3717803 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 43.0 4.04e-01 84.3% 99.6%
3715769 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.52 43.0 3.90e-01 86.4% 98.0%
3481289 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.51 33.0 3.96e-01 81.8% 95.6%
4471031 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 34.0 3.36e-01 78.8% 61.4%
3514283 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.51 32.0 3.65e-01 77.3% 80.6%
5039785 632.22.1.200 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PF26119 0.50 25.0 3.57e-01 71.7% 100.0%
3724188 109.3.1.93 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF6987 0.50 39.0 3.80e-01 84.8% 73.5%
D3 medium residues 208-293
PDB
Domain cluster: rep: envelope_glycoprotein_H__YP_010087581__Cervid_alphaherpesvirus_3__2115790__D207-328
CATH (51)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xqyA01 3.30.500.50 Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › 0.83 63.0 4.87e-01 98.8% 38.8%
5nz7A01 2.70.98.40 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Glycoside hydrolase, family 65, N-terminal domain 0.70 63.0 4.23e-01 100.0% 69.4%
6fmeA03 2.20.220.10 Mainly Beta › Single Sheet › Glycosyl hydrolase fold › alpha-Amylases 0.70 49.0 5.69e-01 89.5% 100.0%
3p24A01 2.40.128.470 Mainly Beta › Beta Barrel › Lipocalin › 0.68 57.0 4.67e-01 90.7% 62.7%
1n9eA01 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.68 60.0 3.71e-01 98.8% 67.2%
7wa9A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.68 47.0 3.99e-01 72.1% 88.7%
3pgbA01 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.67 59.0 3.67e-01 98.8% 66.2%
3rbyA02 2.40.128.310 Mainly Beta › Beta Barrel › Lipocalin › Protein HRI1, C-terminal domain 0.67 45.0 4.41e-01 87.2% 63.2%
1a2vA03 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.66 57.0 3.69e-01 98.8% 78.6%
1nkgA01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.66 58.0 4.20e-01 100.0% 81.7%
1mmuA00 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.65 57.0 3.83e-01 98.8% 89.1%
3w7tA01 2.70.98.50 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › putative glycoside hydrolase family protein from bacillus halodurans 0.64 57.0 4.16e-01 98.8% 67.2%
3eb8B01 3.10.450.460 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › EspG protein, N-terminal domain 0.63 36.0 4.20e-01 83.7% 80.3%
6psyA01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.62 47.0 3.47e-01 80.2% 40.1%
6fopA01 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.62 54.0 4.05e-01 100.0% 65.9%
1vr8A00 3.40.1000.20 Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › TM1622-like 0.61 44.0 3.80e-01 75.6% 68.9%
7jjtA01 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.61 44.0 4.37e-01 74.4% 95.5%
5do8B03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.60 42.0 4.41e-01 73.3% 97.4%
2avtA02 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.59 52.0 4.01e-01 98.8% 92.0%
2ffsA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.59 46.0 3.84e-01 87.2% 49.0%
1cgtA02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.59 42.0 4.15e-01 75.6% 92.6%
5gv0A00 2.40.160.110 Mainly Beta › Beta Barrel › Porin › 0.58 52.0 4.20e-01 97.7% 53.1%
4ktpB02 2.60.420.10 Mainly Beta › Sandwich › Maltose phosphorylase, domain 3 › Maltose phosphorylase, domain 3 0.58 45.0 4.61e-01 82.6% 100.0%
3t0pA02 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.58 51.0 3.97e-01 98.8% 91.7%
5e1qA03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.58 43.0 4.16e-01 79.1% 100.0%
4akmB00 2.40.160.110 Mainly Beta › Beta Barrel › Porin › 0.57 52.0 4.22e-01 98.8% 54.8%
2bklA02 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.57 40.0 2.77e-01 74.4% 81.7%
2qziA00 3.40.1720.10 Alpha Beta › 3-Layer(aba) Sandwich › Streptococcus thermophilus LMG 18311 protein like › Streptococcus thermophilus LMG 18311 protein like 0.57 48.0 4.60e-01 91.9% 97.0%
3imhA00 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.57 45.0 3.14e-01 89.5% 56.9%
5upiA01 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.57 49.0 3.92e-01 100.0% 84.6%
2v7sA00 3.30.2030.20 Alpha Beta › 2-Layer Sandwich › TBP-like › 0.57 45.0 3.54e-01 83.7% 72.8%
4tr6A01 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.56 49.0 3.90e-01 97.7% 88.9%
4ix3A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.56 38.0 3.53e-01 70.9% 77.9%
4h0aA00 3.40.33.10 Alpha Beta › 3-Layer(aba) Sandwich › Pathogenesis-related Protein p14a › CAP 0.55 50.0 3.44e-01 100.0% 47.3%
2f0cA02 2.60.40.1830 Mainly Beta › Sandwich › Immunoglobulin-like › Phage tail base-plate Siphoviridae RBP, head domain 0.55 40.0 3.80e-01 76.7% 96.2%
1yqfB00 3.10.280.10 Alpha Beta › Roll › Mitochondrial Matrix Protein; Chain A › Mitochondrial glycoprotein 0.55 39.0 3.07e-01 86.0% 36.2%
3w9kA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.55 48.0 4.15e-01 97.7% 70.4%
5h9kA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.55 43.0 3.61e-01 87.2% 94.2%
3ge2A00 2.40.128.50 Mainly Beta › Beta Barrel › Lipocalin › 0.54 34.0 3.39e-01 83.7% 60.7%
2ovsA00 2.40.128.380 Mainly Beta › Beta Barrel › Lipocalin › T3SS negative regulator GrlR 0.54 47.0 4.25e-01 97.7% 70.3%
4hbrA00 3.10.450.360 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.54 44.0 3.78e-01 88.4% 55.0%
4fr9A00 3.10.450.360 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.54 45.0 3.87e-01 100.0% 56.7%
2avtB01 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.53 47.0 3.75e-01 97.7% 89.0%
3v8uA04 2.40.160.90 Mainly Beta › Beta Barrel › Porin › 0.53 44.0 3.69e-01 89.5% 90.1%
3dxpA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.53 36.0 3.56e-01 70.9% 73.1%
1x99A00 2.60.270.20 Mainly Beta › Sandwich › Mutm (Fpg) Protein; Chain: A, domain 2 › Cytolysin/lectin 0.52 46.0 3.89e-01 98.8% 87.6%
2ntkB00 3.60.20.20 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Inosine monophosphate cyclohydrolase-like 0.52 45.0 3.42e-01 94.2% 68.3%
2xe4A02 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.51 39.0 2.66e-01 83.7% 49.4%
7snsB01 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.51 41.0 3.32e-01 86.0% 66.7%
3zpmA00 3.15.10.10 Alpha Beta › Super Roll › Bactericidal permeability-increasing protein; domain 1 › Bactericidal permeability-increasing protein; domain 1 0.51 42.0 3.19e-01 91.9% 73.0%
1p32B00 3.10.280.10 Alpha Beta › Roll › Mitochondrial Matrix Protein; Chain A › Mitochondrial glycoprotein 0.51 41.0 3.29e-01 88.4% 48.5%
ECOD (47)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1554358 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.85 80.0 4.68e-01 100.0% 15.3%
2095476 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.84 79.0 4.66e-01 100.0% 15.6%
4956163 71.1.1.0 ↗ beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB 0.84 49.0 3.76e-01 88.4% 28.3%
119302 3146.1.1.0 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain 0.81 64.0 4.19e-01 100.0% 21.7%
5081796 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.75 41.0 3.25e-01 81.4% 27.6%
2095503 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.74 68.0 4.12e-01 100.0% 17.0%
5036898 881.1.1.0 ↗ a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like 0.73 53.0 4.46e-01 76.7% 79.2%
2099578 12.3.1.12 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_transf_36 0.70 63.0 3.98e-01 98.8% 48.5%
3962450 9.27.1.0 ↗ beta barrels › Lipocalins/Streptavidin › LpqH › LpqH 0.69 50.0 4.70e-01 98.8% 61.9%
3799467 4026.1.1.0 ↗ a+b three layers › a+b domain in Rap/Ran-GAP (Pfam 02145) › a+b domain in Rap/Ran-GAP (Pfam 02145) › a+b domain in Rap/Ran-GAP (Pfam 02145) 0.69 43.0 3.52e-01 89.5% 34.8%
3584281 12.3.1.13 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_38C 0.68 61.0 4.23e-01 100.0% 84.8%
3229481 71.1.1.21 ↗ beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › PF25897 0.68 48.0 3.49e-01 88.4% 28.8%
4978331 331.10.2.0 ↗ a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase 0.68 47.0 5.16e-01 72.1% 95.7%
3223040 12.3.1.13 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_38C 0.68 60.0 4.32e-01 100.0% 90.2%
3990496 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.66 45.0 4.97e-01 89.5% 87.1%
2027 12.3.1.17 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › RhgB_N 0.66 58.0 4.21e-01 100.0% 82.0%
2717534 12.3.1.31 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › YgjK_N 0.65 59.0 4.10e-01 100.0% 63.6%
3789058 210.1.4.1 ↗ a+b four layers › Ntn/PP2C › Ntn › (Glycosyl)asparaginase › Asparaginase_2 0.65 57.0 3.90e-01 98.8% 98.7%
3222216 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.64 41.0 4.48e-01 89.5% 80.0%
5044805 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.64 41.0 4.52e-01 88.4% 81.4%
4989818 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.63 56.0 4.19e-01 100.0% 85.9%
2389389 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.63 55.0 4.16e-01 100.0% 75.3%
5014685 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.62 40.0 4.52e-01 89.5% 86.2%
5032559 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.62 51.0 5.03e-01 98.8% 83.3%
3953302 331.2.1.1 ↗ a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.62 42.0 3.98e-01 70.9% 89.4%
3188851 9.14.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Uncharacterized protein YLR301W › Uncharacterized protein YLR301W › HRI1 0.61 50.0 4.60e-01 87.2% 69.1%
3418904 284.1.3.0 ↗ a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.61 42.0 4.02e-01 88.4% 61.0%
4946526 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.61 53.0 3.79e-01 100.0% 93.9%
3590243 6044.1.1.1 ↗ a+b three layers › DUF1827-like › DUF1827-like › DUF1827-like › DUF1827 0.60 47.0 4.43e-01 83.7% 99.0%
3955351 12.6.1.1 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related › Glyco_hydro_65C 0.60 39.0 4.47e-01 77.9% 95.0%
5024359 12.1.1.3 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Alpha-amylase_C 0.60 43.0 4.49e-01 75.6% 98.8%
3596915 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.59 48.0 2.98e-01 90.7% 30.2%
5014277 274.1.1.0 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.59 38.0 3.86e-01 88.4% 65.9%
5021455 4252.1.1.0 ↗ beta barrels › AttH-like › AttH-like › AttH-like 0.58 53.0 4.49e-01 98.8% 83.7%
3638937 220.1.1.195 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_fung_RdRP 0.58 40.0 3.23e-01 72.1% 71.2%
3707133 12.3.1.19 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Gal_mutarotas_2 0.57 47.0 3.60e-01 90.7% 81.4%
3427945 284.1.3.0 ↗ a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.57 40.0 3.80e-01 87.2% 62.0%
184900 6044.1.1.1 ↗ a+b three layers › DUF1827-like › DUF1827-like › DUF1827-like › DUF1827 0.57 48.0 4.60e-01 91.9% 97.0%
185647 3369.1.1.1 ↗ beta meanders › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 › Lamp2-like_luminal 0.57 52.0 4.22e-01 98.8% 55.5%
4942439 4252.1.1.0 ↗ beta barrels › AttH-like › AttH-like › AttH-like 0.57 52.0 4.30e-01 98.8% 81.4%
4014982 7579.1.1.0 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.57 40.0 2.73e-01 73.3% 53.4%
5035423 295.1.1.0 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.54 39.0 4.01e-01 93.0% 77.6%
3613138 12.6.1.1 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related › Glyco_hydro_65C 0.53 39.0 4.28e-01 94.2% 97.1%
3578232 77.3.1.4 ↗ beta meanders › open-sided beta-meander › CPAP G-box domain › CPAP G-box domain › PF28998 0.53 42.0 3.05e-01 84.9% 90.7%
3588455 274.1.1.0 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.51 33.0 3.58e-01 94.2% 80.0%
3782417 883.1.1.18 ↗ a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › PF26545 0.51 45.0 3.54e-01 98.8% 88.1%
4962687 4972.1.1.1 ↗ beta barrels › barrel domain in CV3147-like proteins › barrel domain in CV3147-like proteins › barrel domain in CV3147-like proteins › DUF917_C 0.50 45.0 3.95e-01 97.7% 75.2%
D4 medium residues 432-526
PDB
Domain cluster: rep: envelope_glycoprotein_H__NP_045257__Equid_alphaherpesvirus_4__10331__D432-555
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 21.1 1.60e-04 96.8% 16.0%
CATH (47)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3au3A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.73 66.0 4.60e-01 100.0% 39.5%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 50.0 4.48e-01 72.6% 69.9%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 51.0 5.66e-01 76.8% 97.3%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 63.0 5.41e-01 98.9% 66.9%
6wv5A01 1.20.1440.130 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain 0.71 55.0 4.86e-01 82.1% 66.2%
4cruB00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.71 63.0 4.53e-01 97.9% 35.2%
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 52.0 5.23e-01 77.9% 84.7%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 56.0 4.69e-01 87.4% 65.4%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.69 50.0 5.30e-01 77.9% 89.4%
3n2oA03 1.20.58.930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 55.0 5.57e-01 88.4% 91.7%
4dloB02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.67 61.0 5.68e-01 100.0% 83.8%
5cwkA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.66 60.0 4.93e-01 100.0% 56.5%
1ugoA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.65 47.0 4.71e-01 76.8% 73.7%
2e9xD01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 51.0 4.56e-01 86.3% 75.2%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.64 46.0 4.34e-01 75.8% 93.2%
2d9dA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.64 48.0 4.99e-01 78.9% 84.3%
3oxfA05 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 46.0 5.02e-01 91.6% 96.0%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.64 46.0 3.88e-01 74.7% 77.0%
3kp9A01 1.20.1440.130 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain 0.64 53.0 4.49e-01 92.6% 61.1%
2kmfA01 1.20.58.810 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 0.64 48.0 4.70e-01 81.1% 74.5%
7eq1R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 44.0 3.12e-01 71.6% 72.1%
2qvaA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.62 53.0 4.86e-01 96.8% 79.1%
2zueA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.62 50.0 4.74e-01 92.6% 72.3%
3fnbA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.61 50.0 4.75e-01 94.7% 75.4%
3urzA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 54.0 4.25e-01 98.9% 50.5%
2b1eA02 1.20.1310.30 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › 0.59 52.0 4.51e-01 100.0% 90.1%
2ccyA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.59 43.0 3.91e-01 75.8% 94.5%
4x5mA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.58 42.0 4.42e-01 77.9% 89.5%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.58 42.0 3.99e-01 76.8% 70.9%
2a2fX02 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.57 50.0 4.56e-01 100.0% 84.5%
1vdyA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 49.0 4.41e-01 100.0% 85.7%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.56 44.0 4.11e-01 91.6% 66.9%
1s2xA00 1.20.190.30 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › CAG pathogenicity island protein, CagZ 0.56 47.0 3.90e-01 94.7% 97.2%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.56 39.0 3.75e-01 72.6% 87.2%
3lsjA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 43.0 3.72e-01 84.2% 83.0%
2f07B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 47.0 3.84e-01 100.0% 79.1%
2ip6A00 1.20.1440.140 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.54 38.0 3.95e-01 72.6% 92.0%
1fx8A00 1.20.1080.10 Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. 0.53 46.0 3.47e-01 100.0% 78.7%
2w53B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 44.0 3.68e-01 92.6% 59.0%
1zoyD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.53 42.0 4.14e-01 85.3% 87.3%
1yozA00 1.10.3200.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like 0.52 44.0 4.19e-01 94.7% 96.5%
2fd5A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 40.0 3.72e-01 88.4% 71.2%
4cgrB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 44.0 3.64e-01 100.0% 92.7%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.51 37.0 3.57e-01 76.8% 89.9%
4rflA02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.51 44.0 3.51e-01 96.8% 91.5%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.51 41.0 4.35e-01 94.7% 98.8%
1zk8B02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 41.0 3.68e-01 89.5% 63.6%
ECOD (53)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4003476 109.4.1.1710 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF7627 0.75 64.0 5.18e-01 91.6% 66.9%
3940580 604.6.1.14 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › RasGAP_C 0.75 55.0 5.11e-01 75.8% 80.0%
3743147 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.75 68.0 4.27e-01 100.0% 23.4%
3992675 109.4.1.313 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › UTP20_N 0.75 65.0 4.76e-01 95.8% 40.8%
3191000 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.74 67.0 4.38e-01 100.0% 41.8%
3634660 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.74 67.0 4.19e-01 100.0% 32.5%
4001572 109.4.1.472 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RAI16-like 0.74 68.0 4.14e-01 100.0% 30.4%
3720326 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.73 66.0 4.19e-01 100.0% 39.7%
3697513 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.72 64.0 4.67e-01 100.0% 40.4%
3191797 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 63.0 5.08e-01 100.0% 65.3%
3230272 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 63.0 4.29e-01 100.0% 27.5%
5000552 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.70 60.0 5.99e-01 100.0% 91.0%
3810544 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.69 53.0 4.75e-01 82.1% 86.7%
3390261 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.69 52.0 5.39e-01 80.0% 85.6%
3867624 109.4.1.3415 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28426 0.69 61.0 4.48e-01 100.0% 60.4%
3274991 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 58.0 4.08e-01 100.0% 29.0%
3648543 6155.1.1.16 ↗ alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PF28566 0.68 59.0 4.70e-01 95.8% 53.7%
4016725 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.68 40.0 4.11e-01 71.6% 61.1%
3519581 604.12.1.4 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT1 0.68 50.0 4.49e-01 78.9% 81.5%
3833881 6155.1.1.16 ↗ alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PF28566 0.67 58.0 5.23e-01 95.8% 77.7%
3268163 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 59.0 5.13e-01 98.9% 83.2%
3822496 109.4.1.554 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Neurochondrin 0.67 58.0 4.05e-01 98.9% 40.6%
3530149 6171.1.1.1 ↗ alpha bundles › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › JHD 0.67 53.0 5.02e-01 87.4% 84.3%
4982987 3352.1.1.1 ↗ alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3 0.66 58.0 3.83e-01 96.8% 37.4%
4027659 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 59.0 4.20e-01 100.0% 40.7%
3684480 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 56.0 5.28e-01 95.8% 78.3%
3782487 6155.1.1.2 ↗ alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.66 47.0 4.23e-01 75.8% 57.8%
4969464 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.65 49.0 5.06e-01 81.1% 93.3%
4381845 109.4.1.179 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nro1 0.64 57.0 3.90e-01 100.0% 39.7%
3597076 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 56.0 4.46e-01 97.9% 54.9%
3711015 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 52.0 3.93e-01 100.0% 35.8%
3456183 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 54.0 5.32e-01 95.8% 97.0%
3526105 604.3.1.18 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › PF27519 0.63 44.0 4.58e-01 73.7% 80.0%
4989797 5050.1.1.1 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.63 46.0 3.57e-01 77.9% 68.6%
3788386 109.4.1.486 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RPM2 0.62 54.0 4.20e-01 100.0% 62.2%
5034342 6155.1.1.0 ↗ alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter 0.62 45.0 4.84e-01 77.9% 96.2%
3722749 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 53.0 4.09e-01 98.9% 80.9%
3400801 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.61 54.0 4.84e-01 100.0% 83.0%
3784484 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 54.0 4.06e-01 100.0% 75.3%
4987417 622.1.1.0 ↗ alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain 0.60 42.0 4.63e-01 72.6% 94.7%
3237664 5069.1.1.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.59 42.0 3.98e-01 73.7% 85.2%
5005588 5082.1.1.1 ↗ alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.59 43.0 3.50e-01 78.9% 79.0%
4978840 140.1.1.0 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.58 45.0 3.78e-01 97.9% 46.9%
4647835 4106.1.1.1 ↗ few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.57 44.0 3.39e-01 83.2% 78.7%
3530744 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 43.0 3.22e-01 85.3% 55.0%
3959985 633.6.1.0 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.54 41.0 3.56e-01 80.0% 86.9%
4573776 106.1.1.10 ↗ alpha arrays › Globin-like › Globin-like › Globin-like › BCD_RFX 0.53 40.0 3.47e-01 82.1% 72.5%
4058767 7015.1.1.0 ↗ alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.53 40.0 3.60e-01 82.1% 60.7%
3624667 5001.1.1.63 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab 0.53 45.0 3.16e-01 95.8% 45.7%
3185802 7015.1.1.0 ↗ alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.53 40.0 3.65e-01 83.2% 65.2%
3963837 633.6.1.0 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.52 41.0 3.57e-01 84.2% 60.0%
3741875 3277.2.1.1 ↗ alpha arrays › Thymine dioxygenase JBP1 DNA-binding domain-like › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › CHD1-like_C 0.51 41.0 4.14e-01 97.9% 86.0%
4172479 633.6.1.0 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.50 37.0 3.38e-01 80.0% 79.3%
D5 medium residues 527-641
PDB
Domain cluster: rep: envelope_glycoprotein_H__NP_045337__Bovine_alphaherpesvirus_1__10320__D538-631
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 24.1 1.90e-05 82.6% 9.0%
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5ts9B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.62 43.0 3.82e-01 76.5% 49.7%
6cnzF00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.61 42.0 3.80e-01 73.9% 51.3%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.59 34.0 3.59e-01 81.7% 62.7%
1aj3A00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 34.0 3.67e-01 93.0% 67.3%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.57 33.0 3.08e-01 86.1% 44.9%
3o60A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 43.0 3.74e-01 85.2% 78.6%
7d5qA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.54 41.0 3.53e-01 80.0% 85.2%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.52 36.0 3.46e-01 93.0% 61.5%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.52 39.0 3.97e-01 80.0% 96.6%
1jrrA02 3.30.497.10 Alpha Beta › 2-Layer Sandwich › Antithrombin; Chain I, domain 2 › Antithrombin, subunit I, domain 2 0.50 35.0 2.87e-01 72.2% 44.8%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4997858 1075.1.2.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.67 59.0 5.14e-01 94.8% 89.4%
3952992 1079.1.1.7 ↗ alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › SfLAP 0.59 44.0 3.93e-01 79.1% 85.9%
5077932 1075.1.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.59 48.0 3.74e-01 87.8% 83.6%
4946930 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.57 43.0 3.49e-01 80.0% 80.9%
4486453 1079.1.1.7 ↗ alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › SfLAP 0.56 41.0 3.51e-01 77.4% 84.6%
4013947 5069.1.1.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.56 39.0 3.07e-01 70.4% 61.3%
4052351 1175.1.1.0 ↗ alpha complex topology › Apolipoprotein N-acyltransferase transmembrane domain › Apolipoprotein N-acyltransferase transmembrane domain › Apolipoprotein N-acyltransferase transmembrane domain 0.56 46.0 3.66e-01 91.3% 44.5%
3934709 601.1.2.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.56 33.0 3.40e-01 84.3% 60.0%
5076502 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 39.0 3.24e-01 76.5% 77.2%
3779042 5051.1.1.10 ↗ alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease_2 0.53 45.0 3.08e-01 93.0% 67.0%
3263028 5050.1.1.8 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 0.53 39.0 3.14e-01 76.5% 74.5%
4010186 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 38.0 3.17e-01 74.8% 79.0%
3279420 191.1.1.0 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.51 37.0 3.81e-01 75.7% 81.7%
3735188 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.50 42.0 3.27e-01 90.4% 82.0%
3612290 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 45.0 3.65e-01 100.0% 77.3%
D6 medium residues 642-786
PDB
Domain cluster: rep: UL22__YP_003084400__Anatid_alphaherpesvirus_1__104388__D647-783
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17488.8 best Herpes_glycoH_C 78.5 5.60e-22 95.9% 93.6%